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    Cutaneous Mycoses

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    Anand Janagond
    This document summarizes cutaneous mycoses, including dermatophytoses caused by fungi that infect the skin, hair, and nails. It describes the morphology and characteristics of common dermatophyte genera and species. The pathogenesis and clinical presentations of different dermatophyte infections are outlined. Laboratory methods for diagnosing dermatophytoses and mucocutaneous candidiasis are also summarized, along with treatment approaches.

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    Cutaneous Mycoses

    Uploaded by

    Anand Janagond
    341 views34 pages
    This document summarizes cutaneous mycoses, including dermatophytoses caused by fungi that infect the skin, hair, and nails. It describes the morphology and characteristics of common dermatophyte genera and species. The pathogenesis and clinical presentations of different dermatophyte infections are outlined. Laboratory methods for diagnosing dermatophytoses and mucocutaneous candidiasis are also summarized, along with treatment approaches.

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    Fungi causing human skin infections

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    This document summarizes cutaneous mycoses, including dermatophytoses caused by fungi that infect the skin, hair, and nails. It describes the morphology and characteristics of common dermatophyte genera and species. The pathogenesis and clinical presentations of different dermatophyte infections are outlined. Laboratory methods for diagnosing dermatophytoses and mucocutaneous candidiasis are also summarized, along with treatment approaches.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    341 views34 pages

    Cutaneous Mycoses

    Uploaded by

    Anand Janagond
    This document summarizes cutaneous mycoses, including dermatophytoses caused by fungi that infect the skin, hair, and nails. It describes the morphology and characteristics of common dermatophyte genera and species. The pathogenesis and clinical presentations of different dermatophyte infections are outlined. Laboratory methods for diagnosing dermatophytoses and mucocutaneous candidiasis are also summarized, along with treatment approaches.

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    © All Rights Reserved
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    Download as pptx, pdf, or txt
    of 34

    CUTANEOUS

    MYCOSES

    Mycoses - Fungal Infections


    Superficial Mycoses
    Surface Mycoses Dead layers of skin & its

    appendages
    Pityriasis versicolor, Tinea nigra, Piedra
    Cutaneous Mycoses Full thickness of skin
    Dermatophytosis
    Muco-cutaneous Candidiasis
    Subcutaneous Mycoses
    Systemic Mycoses
    Opportunistic Mycoses

    DERMATOPHYTOSES
    DERMATOPHYTES
    Filamentous fungi infecting superficial

    keratinised tissues - Skin, Hair and Nail


    Dermatomycosis v/s Dermatophytosis
    Dermatophytoses = Tinea,Ringworm
    GENUS

    SKIN

    NAIL

    HAIR

    TRICHOPHYTON

    EPIDERMOPHYTO
    N

    MICROSPORUM

    Dermatophytes - morphology
    In Tissues Hypahe

    & Arthrospores
    In Culture
    Thin, septate,

    branching hyphae
    Microconidia Small
    asexual spores
    Macroconidia Large
    asexual spores

    Dermatophytes morphology.
    GENUS

    TRICHOPHYTO
    N

    COLONY

    Powdery/
    Abundan Relatively
    velvety / waxy t
    less
    Elongated,
    Pigmentation
    blunt ends

    Cottony /
    MICROSPORUM velvety/
    powdery
    White / brown
    Powdery,
    EPIDERMOPHY
    TON

    MICROCON MACROCONIDIA
    IDIA

    Greenish
    yellow

    Scanty

    Numerous
    Spindle
    shaped

    Absent

    Many
    Pear-shaped
    in clusters

    Dematophyte species
    Trichophyton
    T. rubrum
    T. violaceum
    T. mentagrophytes
    T. verrucosum
    Microsporum
    M. gypseum
    M. canis
    M. nanum
    Epidermophyton floccosum

    Trichophyton
    mentagrophytes

    Microsporum canis

    Epidermophyton
    floccosum

    Microsporum gypseum

    Trichophyton rubrum

    PATHOGENESIS
    SOURCE
    Patient - Anthropophilic
    Animal - Zoophilic
    Soil Geophilic
    Grow only in keratinised tissues
    Do not penetrate living tissues
    Fungal products Local inflammation
    Hypersensitivity Distant lesions

    CLINICAL
    PRESENTATIONS

    Ringworm Scaly erythematous lesion with

    central clearing

    CLINICAL
    PRESENTATIONS
    Tinea capitis

    Tinea corporis

    CLINICAL PRESENTATIONS
    Tinea barbae
    (Barbers itch)

    Tinea cruris
    (Jock itch)

    CLINICAL
    Moccasin type of
    PRESENTATIONS
    Tinea pedis
    (Athletes foot)

    Tinea pedis

    Tinea unguium

    Tinea imbricata

    Kerion
    Favus

    Dermatophyte Hair Infection


    Ectothrix

    Endothrix

    ID Reaction (Dermatophytid)
    Dermatophyte

    infection
    Hypersensitivity ID
    reaction at a distant
    site
    ID lesions sterile
    Disappear after

    treating the primary


    lesion

    LAB DIAGNOSIS
    SPECIMENS: in

    sterile paper packets


    Skin scrapings
    Nail clippings
    Plucked Hair
    WOODs Lamp

    MICROSCOPY
    KOH 10% - Digest

    keratin
    Calcofluor white
    Fluorescent technique
    CULTURE
    On Sabouraud

    Dextrose Agar
    Microscopic study of
    growth

    TREATMENT
    Limited infection Topical antifungals
    Extensive /widespread lesions Oral

    antifungals
    AZOLES Itraconazole, Clotrimazole,

    Ketoconazole, Fluconazole
    Griseofulvin Oral drug of choice
    Terbinafine

    MUCOCUTANEOUS
    CANDIDIASIS

    CANDIDA
    Candida albicans
    Non-albicans

    Candida spp
    Yeast-like fungus
    Pseudohyphae
    Infection of skin &
    mucosa; rarely of
    internal organs

    Pathogenesis
    Candidiasis/ Candidosis/ Moniliasis
    Normal inhabitant of skin and mucosa
    Diabetes mellitus MC risk factor
    Other risk factors AIDS, Steroids,

    Immunosuppression
    Cutaneous Candidiasis
    Mucosal Candidiasis
    Systemic Candidiasis - rare

    CUTANEOUS
    INTERTRIGINOUS
    Skin macerated by

    perspiration
    Groin, perineum,
    axillae,
    inframammary fold
    PARONYCHIA
    Frequent immersion

    of hands in water

    Mucosal candidiasis
    Oral Thrush
    Bottlefed, elderly,

    etc

    Vaginal candidiasis
    Balanoposthitis
    Intestinal candidiasis
    Bronchopulmonary

    Lab Diagnosis
    SPECIMENS:
    Scrapings, swabs, sputum, blood, etc
    Microscopy budding yeast cells,

    pseudohyphae
    Culture
    Germ tube test
    Cornmeal agar Chlamydospore
    Sugar assimilation & Fermentation tests
    Antifungal susceptibility test

    CULTURE
    Sabouraud Dextrose

    Agar Creamy white,


    yeasty odour

    Germ tube test in

    plasma

    Chlamydospores on Cornmeal agar


    Reynold Braude phenomenon

    TREATMENT
    Removal of predisposing factor
    TOPICAL
    Nystatin
    Azoles
    SYSTEMIC
    Amphotericin B
    5 Fluorocytocine
    Azole

    Thank you

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