MNR HOMOEOPATHIC MEDICAL COLLEGE & HOSPITAL, SANGAREDDY

Recognized by:

NATIONAL COMMISSION HOMOEOPATHY, NEW DELHI.

Affiliated To:

KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES

Intern

SYNOPSIS

“A CLINICAL STUDY IN UNDERSTANDING THE EFFICACY OF 50-

MILLESIMAL POTENCIES IN LEUCORRHOEA.”

By

CH. SRISAI VYSHNAVI

UNDER THE GUIDANCE OF

DR. RAJA SATISH

Associate Professor

Department of Organon of Medicine

MNR HOMOEOPATHIC MEDICAL COLLEGE & HOSPITAL, SANGAREDDY

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From:

CH. SRISAI VYSHNAVI

To,

DR. RAJA SATISH

Associate Professor
Department of Organon of Medicine
MNR Homoeopathic Medical College & Hospital, Sangareddy.

Subject: Application to accept my synopsis for dissertation.

Respected Sir,
I Ch. Srisai vyshnavi, would like to forward my application for the approval of my
synopsis under your guidance for the topic, “A CLINICAL STUDY IN UNDERSTANDING
THE EFFICACY OF 50-MILLESIMAL POTENCIES IN LEUCORRHOEA.”
Hope you will approve the same.

Date:
Place: Sangareddy

Yours Sincerely,

Ch. Srisai Vyshnavi

Department of Organon of Medicine
MNR Homoeopathic Medical College &
Hospital, Sangareddy

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From:

DR. RAJA SATISH

Associate Professor
Department of Organon of Medicine
MNR Homoeopathic Medical College & Hospital, Sangareddy.

To,

CH. SRISAI VYSHNAVI

Sub: Acceptance of synopsis for the dissertation. Dear Doctor,

I have accepted your topic, “A CLINICAL STUDY IN UNDERSTANDING THE

EFFICACY OF 50-MILLESIMAL POTENCIES IN LEUCORRHOEA.” for the
dissertation.
Your synopsis will be forwarded to MNRHMC.

Date:
Place: Sangareddy

DR. RAJA SATISH

Associate Professor
Department of Organon of Medicine
MNR Homoeopathic Medical College & Hospital,
Sangareddy.

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MNR HOMOEOPATHIC MEDICAL COLLEGE & HOSPITAL, SANGA REDDY

1. NAME OF THE CANDIDATE CH. SRISAI VYSHNAVI

AND ADDRESS
PRESENT ADDRESS:

MNR HOMOEOPATHIC

MEDICAL COLLEGE & HOSPITAL,

PERMANENT ADDRESS HNO 3-18,

DESHAIPALLY,
KARIMNAGAR.

2. NAME OF THE INSTITUTION MNR HOMOEOPATHIC MEDICAL

COLLEGE & HOSPITAL

3. COURSE OF THE STUDY INTERN

4. DATE OF ADMISSION TO
COURSE

5. TITLE OF TOPIC A CLINICAL STUDY IN UNDERSTANDING THE

EFFICACY OF 50-MILLESIMAL
POTENCIES IN LEUCORRHOEA

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BRIEF RESUME OF INTENDED WORK:

NEED FOR THE STUDY:

In Gynecological practice, vaginal discharge is the commonest reproductive tract infection among
women in many community-based studies in India.

Most of the time it is normal to experience vaginal discharge. It serves an important function in female
reproductive system and helps maintain a healthy and clean vagina. This is because normal vaginal
discharge is slightly acidic, which repels germs.

Excessive normal vaginal discharge is defined as leucorrhoea. It is a thick, yellowish or white vaginal
discharge. However, the amount of discharge, colour or odour may vary due to vaginal infections.

Homoeopathy is the system of medicine that is based on holistic concept of treatment. It treats a patient
suffering from leucorrhoea according to the specifics of her condition. This is because no two
individuals have same symptoms. Homeopathic medicines treat the symptoms as well as prevent the
recurrence of infection.

In Homoeopathy, when compared to other potencies. 50-Millesimal potency has got great advantages. It
helps to hasten the cure.

Hence the present study of A CLINICAL STUDY IN UNDERSTANDING THE EFFICACY OF 50-
MILLESIMAL POTENCIES IN LEUCORRHOEA has been undertaken.

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REVIEW OF LITERATURE:

There are many patients with leucorrhoea who really do not have knowledge about its complications
and its ill effects on day to day life.

Its prevalance in India is about 60% in low socio-economic people.

DEFINITION

Leucorrhoea is strictly defined as excessive normal vaginal discharge

VAGINAL DISCHARGE

PHYSIOLOGICAL PATHOLOGICAL

• Sexual arousal
INFECTIOUS NON-INFECTIOUS
• Pregnancy
• Pre-menses • Detergents e.g., Nonoxynol 9
• Foreign bodies e.g., cervical caps
Vaginal causes
• Viral antiseptics e.g., Policresulin
• Trichomoniasis • Traditional herbal preparations e.g., Snuff
• Bacterial vaginosis • Tumours e.g., carcinoma of the cervix
• Candidiasis
Cervical causes

Endocervicitis / Ectocervicitis
mucopurulent cervicitis

• Herpes simplex virus

• Neisseria gonorrhoeae • Trichomoniasis
• Chlamydia trachomatis
• Herpes simplex virus

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PHYSIOLOGICAL LEUCORRHOEA:

Physiological leucorrhoea is the term used to describe the white discharge that occurs throughout
puberty, pregnancy, and in female babies. It is a typical process without any associated symptoms.

PATHOLOGICAL LEUCORRHOEA:

Pathological kind of leucorrhoea is defined as vaginal discharge that has changed in colour,
consistency, and smell as a result of infections or disorders of the female reproductive system. It
frequently also comes with itchiness, discomfort, and swelling around the labia.

CLINICAL FEATURES:

1. Excess vaginal discharge which is persistent.

2. Change in colour, consistency and odour, yellow/green, thick,milky discharge with a bad odour.
3. Undergarments stain
4. Pain while micturition
5. Weakness and lethargy
6. Pain pelvic region and calves
7. Itching

Types of Vaginal Discharge:

Colour Consistency Amount Odour Problem cause

Less to Normal ovulation,
Clear Mucoid moderate None emotional tension,
Less to None Cervictis, Corynebacterium
Milky Viscid moderate to acrid vaginitis
Thin Less to
White with modera Fusty Vaginal mycosis
flakes te
Less to
Yellow Frothy very high Foetid Trichomonas vaginitis
green
Less to Hypoestrogenism, non-specific
Pink Serous moderate None infection
Less to Vaginitis, cervicitis, cervical
Brown Watery very high Musty neoplasm
Gray, blood Less to Vaginal ulcer, pyogenic vaginitis,
steaked Thin Foul neoplasm of vagina
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very high

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HOMOEOPATHIC MANAGEMENT:
Homoeopathy treats the sick individual as a whole but not the sickness. There are many pioneers who
proved many homoeopathic drugs which are useful in treating leukorrhea.Sepia, Borax,Bovista,
Pulsatilla, Alumina, etc.

50- MILLESIMAL POTENCIES:

50-millesimal potencies or LM potencies are mentioned in the book "Organon of Medicine" by Dr.
Samuel Hahnemann. He introduced this method of dilution and succussion in the 6th editionof his
book, which was published in 1921.

However, the most comprehensive explanation of this method can be found in Aphorism 270 to 279. In
these aphorisms, Hahnemann discusses the preparation of the LM potency, how it differs from the
centesimal (C) potency, and its advantages and limitations. In Aphorism 270, Hahnemann mentions the
starting point for the LM potency, which is one part of the original substance combined with 50,000
parts of diluent. Throughout these aphorisms, Hahnemann provides a detailed step-by-step process of
how the LM potency is prepared, and his reasoning behind this method, as well as practical advice for
its use in clinical practice.

Here are some advantages and disadvantages of 50-millesimal potency, as described by Hahnemann in
the Organon of Medicine:

Advantages:
1. Faster onset of action: This is because the dilution process involves more succussion (vigorous
shaking), which is thought to release the healing potential of the substance more effectively.
2. Precise dosing: LM scale allows for a more precise adjustment of the dose for individual patients
based on their sensitivity and response to the remedy.
3. Safety: They are non-toxic and devoid of any side-effects. They are safe to use for long term
treatment.
4. Cost-effectiveness: they are consideredmore cost-effective than the C potencies.

Disadvantages:
1. Complexity of preparation: It involves multiple steps of dilution and succussion, which can
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make them costlier to produce.
2. Limited availability: LM potencies are still not widely available in many parts of the world.
3. Need for training: It is a newer and less understood method of potency in homeopathy.
4. Potency confusion: Sometimes the use of 0/1 potency is interchanged with 1C potency in the LM
scale leading to mistakes in prescribing the correct potency.

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AIM:

To understand the efficacy of 50-Millesimal Potency in leucorrhoea.

OBJECTIVE

To study the efficacy of 50-Millesimal Potency in treating leucorrhoea.

HYPOTHESIS

RESEARCH HYPOTHESIS
50-Millesimal Potencies are efficient in treating leucorrhoea

NULL HYPOTHESIS
50-Millesimal Potencies are not effective in treating leucorrhoea

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 MATERIAL AND METHODS:

STUDY SETTING:

The subjects of the study will be selected from the patients attending the OPD, IPD, peripheral centers
of MNR Homoeopathic Medical college and Hospital as per inclusion criteria.

STUDY SUBJECTS:Subjects suffering from leucorrhoea will be given the medicine.

STUDY PERIOD: 6 months

SAMPLE SIZE: 20 cases

INCLUSION CRITERIA:

Females of all age group

Females experiencing leucorrhoea
Patients willing to take homoeopathic treatment
EXCLUSION CRITERIA:

Already under treatment by other Homoeopathic practitioner or under any other system of medicine.

MATERIALS:

20 patients selected in MNRHMC OPD basis

Homoeopathic remedies in 50 Millesimal Potencies from Homoeopathic Pharmacy

METHOD OF COLLECTION OF DATA:

From a population a sample of 20 cases will be selected based on inclusion and exclusion criteria. It
will be ensured that patients are made aware of the study in their own language and an informed
consent will be taken from every individual. The symptom totality is taken from every individual and
according to the totality of symptoms, a remedy is selected and give in 50- Millesimal Potency in a
dram bottle.

SELECTION OF MEDICINE:

Medicine is selected according to the totality of symptoms of every individual by case taking.

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LIST OF REFERENCES:

1. De Dutta's Textbook of gynaecology Enlarged & Revised Reprint of Sixth Edition, 2013
November. New Delhi: Jaypee brothers medical Publishers (P) Ltd.

2. Hahnemann, S. (2021). Organon of medicine: Sixth edition. B Jain.

3. Boericke, W. (2008). Pocket Manual of Homeopathic Materia Medica. B Jain.

4. Clarke, J. H. (2013). A dictionary of practical Materia medica volume 1. Theclassics.

5. Naik, K. (2012). Handbook of homoeopathic therapeutics on obstetrics and gynaecology. B Jain.

6. Mohammad Abid, Jyoti, Kapil Kumar, Roomi khan, Salman Ali, Phool Chandra, Renu Rani,
Najam Ali Khan. (2016). Assessment of Leucorrhoea diseases in female students. Journal of
Scientific and Innovative Research; 5(4): 116-118, 5(4): 116-118.

7. Prof. Tewiri, P.V. Dr. Neelam, Dr. kba suliw Kulkarni, mo., (2001). a study of lukol in
leucorrhoea, pelvic inflammatory diseases, and dysfunctional uterine bleeding.

8. Arthy et al. 05 March 2021Evaluation of prevalence, cause, risk factors associated with
leucorrhoea in reproductive age group women.

9. Uma Devi. S October 2013 A study on Prevalence of Leucorrhoea in Women Attending in OPD
of Gynaecology and Obstetrics Department in a Tertiary Hospital International Journal ofResearch in
Health Sciences, 2013,1,3,239-243.

10. Kulkarni. R.M, Durge. P.M 2005 A Study of Leucorrhoea in Reproductive Age Group Women
of Nagpur City

11. Vaginal Discharge Assessment form for Utilization by Primary Health Care Workers in a
Community Setting Ilankoon IMPSI Biochemistry, University of Sri Jayewardenepura, Sri Lanka
Submission: March 06, 2018

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12. Dr. Shivram, Dr. Anjana kumari, Dr. Priyanka Kapoor, august 9 2019 An overview of
leucorrhoeaand its homoeopathic therapeutics

13. Dhiman, K. (2014). Leucorrhoea In Ayurvedic Literature - A Review. Ayurpharm Int J Ayur
AlliSci.,3,73-78.

14. Raphaël Abauleth, Serge Boni, Alphonsine Kouassi-Mbengue, Joachim Konan, Salomon Deza.
(2006). Causation and treatment of infectious leucorrhoea at the Cocody University Hospital
(Abidjan, Côte d'Ivoire). Cahiers d'études et de Recherches Francophones, 6.

15. Dr. Aastha Singh, 2020 Leucorrhoea and its homoeopathic management. 12. Dr. Babitha
RaniJamiwal, 9 august 2018, Medicines for Leucorrhoea of different colour, From Boericke

16. Dr. Manisha Bhatia August 31, 2015, Homeopathy treatment for leucorrhoea, white
vaginaldischarge.

17. Kumar, S., Padubidri, V. G., & Daftary, S. N. (Eds.). (2018). Shaw's textbook of
gynaecology(17th ed.). Elsevier.

18. Kumar, S., Padubidri, V. G., & Daftary, S. N. (Eds.). (2022). Howkins & Bourne: Shaw’s
Textbook of Gynaecology, 18th Edition-E-Book (18th ed.). Elsevier.

19. 9. Chaudhury .m, Chatterjee. Bd, Banerjee. M, 1998 February, A clinic bacteriological study on
leucorrhoea

20. Dr. Shivram, Dr. Anjana kumari, Dr. Priyanka Kapoor, august 9 2019 An
overview of leucorrhoea and its homoeopathic therapeutics

21. Kerkar, P., FFARCSI, & DA. (2017, December 29). What is Leukorrhea & How is it Treated?
Epainassist. https://www.epainassist.com/women/what-is- leukorrhea-and-how-is-it-treated

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22. A Sikarwar – Int J Hom Sci, 2020-homoeopathicjournal.com, Leucorrhoea and Homoeopathy
https://www.homoeopathicjournal.com/articles/ 141/4-1-23-754.pdf

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 9. SIGNATURE OF CANDIDATE

10. REMARKS OF THE GUIDE

11. NAME AND DESIGNATION OF DR. RAJA SATHISH

Associate Professor
11.1 GUIDE
Department of Organon of Medicine
MNR Homoeopathic Medical College
&Hospital, Sangareddy.

11.2 SIGNATURE

11.3 HEAD OF DEPARTMENT

NAME/ SEAL

11.4 SIGNATURE

12. PRINCIPAL

SIGNATURE

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 ANNEXURE – 1
INFORMED CONSENT

I have read and understood the information/ it has been read to me and explained in an understandable language
about the research project:
………………………………………………………………………………………………
Name of Participant

Signature of Participant

Date (DD/MM/YY)

If illiterate

A literate witness must sign (if possible, this person should be selected by the participant and should have no

connection to the research team). Participants who are illiterate should include their thumb-print as well.
I have witnessed the accurate reading of the consent form to the potential participant, and the individual has had

the opportunity to ask questions. I confirm that the individual has given consent freely.

Name of witness AND Thumb print of participant

Signature of witness

Date (DD/MM/YY)

Statement by the researcher/person taking consent

I have accurately read out the information sheet to the potential participant, and to the best of my ability made

sure that the participant understands the procedures to be done:

I confirm that the participant was given an opportunity to ask questions about the study, and all the questions

asked by the participant have been answered correctly and to the best of my ability. I confirm that the individual

has not been coerced into giving consent, and the consent has been given freely and voluntarily.

A copy of this ICF has been provided to the participant

Name of Researcher/person taking the consent

Signature of Researcher /person taking the consent

Date (DD/MM/YY

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