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    FIX SIMULASI - Numerical Simulation From Mathematical Modelling of HIV Transmission

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    Kurnia Febri Hermawan
    1. The document describes a mathematical model and numerical simulation of HIV transmission between four compartments: susceptible people (S), undiagnosed HIV positive people (I), diagnosed but untreated people (D), and diagnosed and treated people (T). 2. The model is represented by a set of differential equations that describe the flow of people between compartments over time based on transmission and treatment parameters. 3. The results of the numerical simulation show the susceptible population (S) increasing over time while the infected, diagnosed, and treated populations (I, D, T) decrease, indicating a non-endemic transmission scenario where the virus does not spread between compartments.

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    FIX SIMULASI - Numerical Simulation From Mathematical Modelling of HIV Transmission

    Uploaded by

    Kurnia Febri Hermawan
    23 views19 pages
    1. The document describes a mathematical model and numerical simulation of HIV transmission between four compartments: susceptible people (S), undiagnosed HIV positive people (I), diagnosed but untreated people (D), and diagnosed and treated people (T). 2. The model is represented by a set of differential equations that describe the flow of people between compartments over time based on transmission and treatment parameters. 3. The results of the numerical simulation show the susceptible population (S) increasing over time while the infected, diagnosed, and treated populations (I, D, T) decrease, indicating a non-endemic transmission scenario where the virus does not spread between compartments.

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    1. The document describes a mathematical model and numerical simulation of HIV transmission between four compartments: susceptible people (S), undiagnosed HIV positive people (I), diagnosed but untreated people (D), and diagnosed and treated people (T). 2. The model is represented by a set of differential equations that describe the flow of people between compartments over time based on transmission and treatment parameters. 3. The results of the numerical simulation show the susceptible population (S) increasing over time while the infected, diagnosed, and treated populations (I, D, T) decrease, indicating a non-endemic transmission scenario where the virus does not spread between compartments.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    23 views19 pages

    FIX SIMULASI - Numerical Simulation From Mathematical Modelling of HIV Transmission

    Uploaded by

    Kurnia Febri Hermawan
    1. The document describes a mathematical model and numerical simulation of HIV transmission between four compartments: susceptible people (S), undiagnosed HIV positive people (I), diagnosed but untreated people (D), and diagnosed and treated people (T). 2. The model is represented by a set of differential equations that describe the flow of people between compartments over time based on transmission and treatment parameters. 3. The results of the numerical simulation show the susceptible population (S) increasing over time while the infected, diagnosed, and treated populations (I, D, T) decrease, indicating a non-endemic transmission scenario where the virus does not spread between compartments.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 19

    Numerical Simulation from

    Mathematical Modelling of HIV


    Transmission

    Kurnia Febri Hermawan


    081711233076
    Background

    Source : WHO
    IDENTIFICATION PROBLEM
    • How the result of numerical simulation and interpretation from
    mathematical models of HIV transmission?
    Purpose
    • Knowing the result of numerical simulation and interpretation
    from mathematical models of HIV transmission
    Benefit
    • The benefit of this research is to know and understand the spread
    of HIV transmission so we can control the spread of HIV in
    humans
    Scope of Problem
    TRANSMISSION DIAGRAM
    and
    MATHEMATIC MODEL
    COMPARTMENTS

    𝐷𝑒𝑠𝑐𝑟𝑖𝑝𝑡𝑜𝑛 𝑆𝑦𝑚𝑏𝑜𝑙
    Susceptible people S
    Undiagnosed HIV positive people I
    People who are diagnosed of HIV but are D
    not in a treatment program
    People who are diagnosed of HIV and T
    enrolled in a treatment program
    Transmission Diagram
    MATHEMATIC MODEL
    𝑑𝑆 𝑆
    = ʌ − λ − 𝑑𝑆 𝑆 (1)
    𝑑𝑡 𝑁
    𝑑𝐼 𝑆
    = λ − 𝑑𝐼 𝐼 − 𝛼𝐼 (2)
    𝑑𝑡 𝑁
    𝑑𝐷
    = 𝛼𝐼 − γD − 𝑑𝐷 𝐷 + 𝜌𝑇 (3)
    𝑑𝑡
    𝑑𝑇
    = γD − 𝑑 𝑇 𝑇 − 𝜌𝑇 (4)
    𝑑𝑡
    λ = 𝛽𝐼 𝐼 𝑡 + 𝛽𝐷 𝐷 𝑡 + 𝛽𝑇 𝑇 𝑡
    𝐷𝑒𝑠𝑐𝑟𝑖𝑝𝑡𝑜𝑛
    PARAMETER
    𝑆𝑦𝑚𝑏𝑜𝑙 𝑉𝑎𝑙𝑢𝑒

    Transmission rate for compartement I 𝛽𝐼 0.214

    Rasio of transmission rate for D and I 𝛽𝐷 0.75


    𝑎=
    𝛽𝐼

    Rasion of transmission rate for T and I 𝛽𝑇 0.1


    𝑏=
    𝛽𝐼
    Death rate for compartement S 𝑑𝑆 0.007

    Death rate for compartement I 𝑑𝐼 0.063

    Death rate for compartement D 𝑑𝐷 0.0427

    Death rate for compartement T 𝑑𝑇 0.0652

    Trearment drop-out rate 𝜌 0.0169

    Influx of suspectible by birth and ʌ 276


    emigration
    Time-dependent diagnoseis rate 𝛼(𝑡) 0.0602t-120.585, t>2010

    Time-dependent treatment enrolment rate γ(𝑡) 0.01886t-37.807, t>2005


    PROGRAM
    RESULT
    and
    INTERPRETATION
    CHART OF SUSPECTIBLE HUMAN
    CHART OF INFECTION HUMAN

    Figure 1 Figure 2
    CHART OF DIAGNOSED HUMAN

    Figure 1 Figure 2 Figure 3


    CHART OF TREATMENT HUMAN

    Figure 1 Figure 2 Figure 3


    Conclusion
    From the four figures, it can be concluded that the population of
    S(Suspectible Humans) is increasing and the three other figure
    IDT(infections,Diagnosed and Treatment) transmitting
    populations tend to decrease, so the choice of parameters in the
    journal is a case of non-endemic
    It’s mean no transmission between compartement S and three
    other compartement (IDT).

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