Appendix of Organon145-293

PRESENTED BY
Dr. SHARY KRISHNA .B .S
18th BATCH P.G.T.
Dept. of Organon of Medicine, Homoeopathic Philosophy,
Chronic Diseases & Psychology

Under the guidance of

Dr. SUBHAS SINGH M.D. (HOM.), Ph. D.

H.O.D. Dept. of Organon of Medicine, Homoeopathic Philosophy, Chronic
Diseases, & Psychology

On 02.01.2018

Venue - Dept. of Organon of Medicine

NATIONAL INSTITUTE OF HOMOEOPATHY,
145- 1st edition

 Old chronic diseases not subject to any important change

 Present certain fixed fundamental symptoms
 Sometimes equal homoeopathically suitable remedies may
be employed alternately with advantage

in 1st edition
3rd and 4th edition FN-145

 Only in complicated disease

 eg: in addition to venereal chancre disease the
condylomatous or mayhap the psoric disease dwells in the
body
 It is impossible to complete cure with a single medicine
 Here each appropriate homoeopathic (specific) remedy
for one and other disease must be employed alternately
 Best mercurial preparation the alternation with the best
preparation of Sulphur until both are cured
161- local diseases
 So called local malady arising from internal causes and persisting on a
particular spot
 Cannot be produced with out the consent of the whole of the rest of
the health and without the participation of all other sensitive and
irritable parts,
 Small quantity of homoeopathically adapted medicine put on the
tongue or introduced into the stomach
 Watchful sensitiveness to medicinal forces inherent in all part of the
living body.
 Susceptibility for medicinal stimuli distributed through the
whole organism

 1st edition
189 local malady
 “It could not make its appearance at all without the
consent of the whole of the rest of the health and without
the participation of all the rest of the sensitive and
irritable parts of all the living organs of the whole body.”

 2ed 3ed and 4th edition this clause is differently word

 Idea same as 5th
164
 Every local remedy used alone
 Externally
 Restores health (at it seldom does)
 Unable to do this unless it has at the same time a
homoeopathic curative influence on the internal
morbid state
 IT WOULD HAVE CURED EQUALLY WELL HAD IT BEEN
EMPLOYED INFERNALLY ONLY AND NOT AT ALL
EXTERNALLY.
 1st edition
164 FN 1st edition
eg: of cure in local remedies
 Some eczema- Cantharides
 Exanthemata - application of mercurial
preparations
 Cure occurred only because they are capable
at the same time of removing the internal
morbid state

 Eg'sshowing external remedies had effected

the whole organisms with their curative power
164 FN
2ed and 3rd advantage of the only internal
treatment of local malady
 Disadvantage of local treatment
 Dangerous risk : local remedy on large surface of skins if
divested of its at cuticle
 Shall not be able properly to regulate and moderate the dose
 Danger that the possibly un-homoeopathic remedy may only
burn away or making the unremoved disease thereafter all
worse and still more difficult to cure
 Internal homeopathic remedy in suitable dose is the surest
proof of the complete eradication of the whole disease alone
with local morbid procress
 196
 5th edition idea--–the seat of action ---more rapid change in it.
 1st editions has.
 Medicine are observed to produce a more rapid effect on the
seat of their application than on more remote parts
 Footnote
 Eg: Injection of cherry laurel water in to the anus of animals
shows its spasmodic action first in the lower extremities, later
in the upper parts
 And on the appear parts first when it is introduced into the
stomach
214
 In some chronic diseases this waking up the rest of the symptoms after
the removal of the local malady occurs so gradually that the aggravation
is only observed after a considerable time.
 Foot note
 Chancre – chief symptom representing the greater part of the internal
general venereal disease
 As long as undisturbed-- no presence of other troublesome symptoms
 If burns the chancre away – removes it locally – great injury of the patient
 General disease now burst
 inguinal buboes– soon
 late --- often only after many months – ulceration of the tonsils, eruptions
of papules or spots, Flat, painless smooth, round cutaneous ulcers, rough
growths on the uvula Constant tickling cough etc
 Give place to venereal symptoms of one kind or another.
 Mercurial remedy for a long time
 Never knows if and when the disease has been eradicated
 Continued employement of powerful remedy as mercury (syphilis+
Psora)
 Insidious mercurial disease added to the old malady and two unite to
form MASKED VENEREAL DISEASE
 Which cannot be cured either by Mercury alone or HeparSulphur
alone
 Important local symptom the chancre- the most permanent
unchanging of all venereal phenomena
 internal anti syphilitic Mercurial treatment--entire disease is
perfectly cured by the internal remedy
 Another Eg: of bad effects of local
treatment
 Enucleation of old steatomoas tumors [ observed by BH
and Ricter]
 Follow -– Growth of fresh ones ,Suppuration, Paralysis,
Caries of Bones
 Eg :Old leg ulcer
 death of candidate of ministery who suppressed the
itch before the day of preach
 Great persistence , extreme painfulness of the local
symptom
 Torments the patient of many years grows bigger and
become worse
 eg: Old leg ulcers of aged persons
 terrible and frightful Internal disease
 Alleviating substitute on the least dangerous part of the
organism-the external parts
 Cause of frequent occurrence of rapid death after
destruction of the local affection and treatment of
practitioner of Ordinary medicine
 eg: Drying up ulcers of leg by means of Oxide of Zinc
Different diseases demand different
rules of treatment
 Topical Remedies: Improper and Unjustifiable
 chancres
 venereal buboes
 inguinal ulcers
 Eg: of external remedy with good effect
 Facial Cancers- Arsenic externally- ulcerated surface is
destroyed
 Internal general dyscsasia- lies at root of facial ulcer
cured by internal administration of appropriate
Homeopathic remedy –Perfect cure of the entire disease
Eg: of external remedy with good effect
 Condylomatous disease not cure by mercury (local t/t) caustics, cautery,
cutting, ligature.- No real relief was caused by the one sided destruction
 Local t/t- burst out aggravated in anus, axillae, neck,scalp, buccal
cavity I lips –Serious effect of the body, shortening of tendons

 Juice of Thuja-very small dose of decillion fold

dilution internally
 internal Remedy – Considereble amelioration

 Bathe the condylomata externally with undiluted

juice of Thuja
 Perfect external + internal cure
 This is almost only Chronic miasmatic disease with local
symptom, which, when it has attained a great
height,permits of the employment of the homoeopathic
remedy also externally.
248
Untypical alternating diseases

 Remedy corresponds to all these

alternating states
 Contains almost all of them in its
pathogenesis
 Thus remedy will then specifically rapidly
extinguish the entire disease at once
249
 If morbid alternating states are perfectly opposite to one
another
 Selected remedy seldom corresponds homeopathically to both
states
 If homeopathically suitable for one state, it can only serve in a
palliative manner for the opposite alternating states of the disease
 Administration–
 Immediately after the cessation of the stronger alternating state
 immediately at the commencement of that period of the disease to which the
remedy only corresponds antipathically
 Second dose of sane remedy- Seldom required
 Ist dose –Remove the entire disease even before before the expiry
of its period of action
 241-Duration of the action of Remedy
 Duration of the action on the healthy body, by any remedy in diverse
disease, in patient with different constitutions
 FN --Most acute- Few hours
 Most chronic disease- Same dose need several weeks
 Duration of action of remedy conforms to duration of action of
disease
 3erd edition
 Some remedy exhaust their action even in large doses in 24 hours
 Action of cherry laurel water and naphthas may be shorter
 Other remedies complete their action only in several days, a few
indeed in several weeks
 It can be ascertained from the effect observed in every particular
case but never hypothetically determined
242

 Progressive
improvement continues from
the medicine last administered-
 wetake for granted does the duration of
the action of the helpful medicine
continues-
 No Repetition
243

 Remedy acted in a proper homoeopathic manner

 Improved state remains observable even after
the expiry of its action
 Good work continue even if repeated several
hour after in acute disease
 In chronic disease –Several days after cessation of
action of the former remedy
244

 Itis improper, useless and irrational to give

another dose of remedy when improvement
from first dose is happening
245 if interfered
 If even one dose of same remedy repeated before the
improvement has begun to stand still in every
direction-only aggravate the state
 Medicinal disease mixed up with the rest of the
symptoms of the disease
 A kind of complicated and aggravated disease.
 We disturb the amelioration affected and still to be
expected from the first dose, if we give a second dose
of the same originally well chosen remedy before the
expiry of the period of the first, we thereby delay the
recovery.
246-improvement stop + no perfect cure
 If improvement now comes to a stop
 Not yet attained to perfect cure
 careful Investigation of what remains of the
improved disease
 Small alternations in the group f symptoms
 fresh dose of the hitherto efficacious remedy
no longer Homeopathically suitable
 But other more appropriate for those
remaining symptoms
246 FN
Repetition and administration of remedy
 Forms the part of the preface by Hahnemann to Bonninghausen’s Repertory of Antipsoric in 1833
 Remainder of the preface is in the note to 288 aph. It is found only in 5th edition
 Hahnemann's latest practice with respect to administration and repetition of fee medicine is
thus described in the preface for the third part of tf his work on chronic disease published in
1837
 If a small globule of one of the highest dynamisation of a medicine laid dry on the tongue, or
moderate olfaction in a phial containing once or several of such globules show itself to be
smallest weakest dose of the shortest duration of action {though there are plenty of patients of
such an excitable mature as to be affected thereby to a sufficient extent for the cure of slight
acute diseases, for which the remedy has been homoeopathically selected }
 We can easily understand that the incredible variety in patients as regards their excitability
their age, their mental and corporeal development, their vital force and especially the nature of
their disease (which in one case may be natural and simple and of recent origin, in another
natural, simple but of long standing, in another complicated - the union of several miasms -, in
another, and this is the commonest and worst case, ruined by wrong medicinal treatment and
burdened with medicinal diseases) demands a great variety in their treatment, as also in the
regulation of the doses of medicine needful for them".
Solution in divided dose and their repetition
 "Experience has taught me, as it has also, doubtless, the best of my followers,
that it is more useful in diseases of any importance (the most acute not
excepted, and all the more in the subacute, chronic and the most chronic) to
give to the patient the powerful homoeopathic medicinal globule or globules
in solution only, and this solution in divided doses;
 for example, a solution formed with from seven to twenty table-spoonfuls of
water, without any addition, given to the patient
 in acute and very acute diseases, every six, four or two hours, and
 when the danger is very great, even every hour or every half-hour, a table-
spoonful at a time, or
 in the case of delicate persons and children only a small part of a table-
spoonful (one or two teaspoonfuls)".
 "In chronic diseases I found it best to allow a dose (to wit, a spoonful) of such
a solution of the appropriate medicine to be taken no seldomer than every
two days, but more generally every day".
To avoid spoiling the solution

 "But as water (even when distilled) begins to spoil after a few days, whereby
also the power of the small quantity of medicine it contains is destroyed, the
addition of a small quantity of spirits of wine was requisite, or where this was
impracticable or could not be borne, I allowed instead a few small bits of
hard-wood charcoal to be put in the aqueous solution, whereby my object was
accomplished; only in the latter case the fluid becomes after a few days of a
blackish colour, from the shaking which is necessary before taking each dose,
as will presently be seen".
Vital force will not admit repetition of
unaltered dose of medicine
 "Before going farther I must make the important observation that our vital
principle does not well admit of the same unaltered dose of medicine being
given to the patient even twice, still less several times in succession. For then
either the good effects of the former dose will be partly done away with, or
there appear new symptoms and sufferings dependent on the medicine, and
that were not formerly present in the disease, which obstruct the cure; in a
word, the medicine, though it may have been chosen accurately
homoeopathic, acts awry, and attains the end in view either imperfectly or
not at all. Hence the many contradictions of homoeopathists among
themselves in respect to the repetition of the dose"
Shaking the phial with 5 or 6 jerks of the
arm
 "But if, for the repeated administration of one and the same medicine (which
is indispensable in order to obtain the cure of a great chronic disease), the
dose be each time changed and modified, although but slightly so, in its
degree of dynamisation, the vital force of the patient accepts quietly and as
it were willingly the same medicine, even at short intervals, an incredible
number of times, with the best result, and each time to the increased
advantage of the patient".
 "This small alteration of the degree of dynamization may be effected by
shaking the phial in which is the solution of the single
globule (or several of them) with five or six smart jerks
of the arm before each time of taking it".
 If aggravation then go to lower potency
at longer intervals
 "When the physician has allowed the several table-spoonfuls of such a solution to be
taken successively in this manner (yet so that when the remedy has one day produced
too powerful an action he lets the dose be omitted for a day),
 he then, if the medicine continues to show itself useful, takes one or two globules of
the same medicine of a lower potency (e.g. if he have previously employed the
thirtieth dilution he now uses one or two globules of the twenty-fourth), dissolves them
in about the same number of table-spoonfuls of water by shaking the bottle, again adds
a little spirits of wine or a few pieces of charcoal, and allows this solution to be
used to the end in the same way or at longer intervals, and even somewhat less
at a time, but each time only after shaking it five or six times,
 as long as the remedy continues to effect improvement and no new symptoms of the
medicine (never experienced by other patients) appear, in which case another medicine
must be employed.
 But if only the symptoms of the disease appear, but increase considerably under the
continued and even moderated use of the medicine then it is time to discontinue for
one or two weeks or even longer, and we way expect to see striking improvement
from it". 1
in acute disease- FN
 (1) "In the treatment of cases of acute disease the homoeopathic physician goes to work in a
similar manner.
 He dissolves one or two globules of the highly potentized well-selected medicine, in seven,
ten or fifteen table-spoonfuls of water (without any addition) by shaking the bottle, and lets
the patient,
 according as the disease is more or less acute, more or less dangerous, take a whole or half
table-spoonful (or even less if it is a child), every half, whole, or every two, three, four or six
hours (after well shaking the bottle each time).
 If the physician observe the occurrence of no new symptoms, he goes on with it at these
intervals, until the symptoms at first present begin to increase; then he gives it more rarely
and in smaller doses".
 "In the cholera, as is well known, the suitable remedy must often be given at much shorter
intervals".
 "Children should get these solutions always only out of their ordinary drinking mugs; a table
or tea-spoon for drinking with is something quite unusual and suspicious to them, and for
that reason they reject this tasteless liquid. Some sugar, may, however, be added to it for
them".
If repetition of same potency
 "After such a portion has been taken and the same
medicine is still found to be necessary, if the physician
wishes to prepare a fresh portion of the same degree
of potency for the patient,
 it is requisite first to shake the new solution as
many times as the number of succussions given to
the former one amount to, and a few times more,
before the patient takes the first dose of it;
 at the subsequent does, however, only five or six times
again".
Rubbed in externally in an aqueous solution
 "But if the diseased organism be acted upon by the physician with the same
medicine at the same time on other sensitive parts besides the nerves of the
mouth and alimentary canal-
 if, I say, the same medicine which is found salutary be at the same time
rubbed in externally in an aqueous solution (even in but a small quantity)
 on one or more parts of the body which are most free from morbid affections
(e.g. , on an arm or a leg or a thigh unaffected by any skin disease, pains or
cramps),
 by this means, the salutary action will be much increased;
 the limbs to be rubbed in this manner may be, moreover, changed
 . In this way the physician gains much more advantage from the
homoeopathically suited medicine for the patient affected by a chronic
disease, and
 can cure him much more rapidly than by merely administering it by the
mouth".
Rubbed in –idea of cure
proof seen in mineral bath of patients with healthy skin
 "This mode of employing the medicine (that has been
found useful internally), by rubbing it into the skin of the
surface of the body, which has been very much tested by
me and is uncommonly efficacious, and is attended by the
most strikingly happy results,
 explains those rare miraculous cures in which patients
with a sound skin, who had long been cripples,
recovered rapidly and forever by bathing a few
times in a mineral water the medicinal constituents of
which were by accident homoeopathically suited for their
chronic disease“2.
FN-Mineral bath for diseased skin-wrong

 (2) they were proportionately injurious to patients who suffered from ulcers and
cutaneous eruptions, which, as happens from other external remedies, they
repelled from the skin, whereupon, after a transient restoration of the patient's
vital force.
 the internal, uncured disease settled in another part of the body much more
important for life and health,
 Eg:s in place of these affections the crystalline lens grew opaque, the optic nerve
became paralysed, the hearing was lost, pains of countless kinds tormented the
patient, his intellectual organs suffered, his spirits became affected, spasmodic
asthma threatened to suffocate him, a fit of apoplexy carried him off, or some
other dangerous or intolerable ailment appeared in their stead.

 Hence the rubbing in of the homoeopathic internal

medicine should never be employed on spots that are
affected by an external disease.
 Rubbed in-in several limbs

 "The limb to be sujected to friction for this purpose

must be free from cutaneous disease;
 if several limbs are free from cutaneous diseases,
 one limbs after another, alternately, on different days
(by preference on the days when no internal medicine
is taken) should be rubbed by means of the hand with
a small quantity of the medicinal solution, until it
becomes dry.
 For this purpose also the bottle must previously have
been shaken five or six times".
 for scrupulous patients
 From a mixture composed of about five table-spoonfuls of pure water and as many of French
brandy - which should be kept in readiness in a stoppered bottle –
 two, three or four hundred drops (according as it is desired to have a stronger or weaker medicinal
solution) should be dropped into a phial, which it should fill about half full, wherein the small
medicinal powder or the globule or globules lie; this should be corked up and shaken until the
medicine is dissolved.
 Of this, one, two, three or, if the irritability and vital powers of the patient seem to require it, a
few drops more, should be dropped into a cup containing a table-spoonful of water, which should
be briskly stirred and given to the patient and, where greater caution is requisite, the half of it
only should be given, and a similar half-spoonful may very well be used for rubbing in, in the way
described".
 "On the days when the latter only is employed, the small drop-phial must be each time shaken
strongly five or six times, just as when the medicine is used internally, and the medicinal drop or
drops, together with the table-spoonful of water, should likewise be well stirred up in the cup".
 "It is better, instead of a cup, to use a phial containing a table-spoonful of water, and to drop the
required number of drops of medicine into it; it is then in like manner to be shaken five or six
times, and the whole or half of it drunk".
 "In the treatment of chronic diseases it is often more useful that the ingestion, and also the
rubbing in, should be done in the evening shortly before going to bed, for then there is less
chance of any disturbance from without than when it is performed in the morning".
Number of jerks
 "As long as I gave the medicines undivided, each all at
once in a little water, I found that potentizing the dilution
bottles with ten succussions acted too strongly
(their medicinal powers became too highly developed),
 and hence I advised but two shakes to be given.
 But for the last few years, since I can now distribute each
dose of medicine, but in an indestructible solution, over
fifteen, twenty, thirty days, and even a longer period, no
potentizing of the dilution phials is too strong for me, and
I again prepare each with ten jerks of the arm. I must,
therefore, herewith retract what I said three years since
in the first part of this work, p. 186".
 Olfaction

 "In cases where, along with extreme weakness, there was great
irritability on the part of the patient, and only smelling at a
phial
 in which were a few small globules of the required
medicine was admissible,
 when it was necessary to continue the medicine for several days,
 I let the patient smell daily in a different phial containing
globules of the same medicine,
 but every time in a lower degree of potency, once or twice
with each nostril, according as I wished to make a smaller or
greater impression".
 Posology
 The note to #246 is remarkable as containing Hahnemann's direction to give all medicines in the
thirtieth dilution in both chronic and acute diseases. This potency he elsewhere informs us he
adopted for the sake of uniformity.
 Previous to recommending this uniform dose, Hahnemann had advised different doses for different
medicines according as they varied from one another in power and energy.
 The variations in Hahnemann's posology at different periods of his life may be seen in an article by
Dr. Hughes in the 36th vol. of the Brit. Journ of Hom., p. 113.
 But that Hahnemann did not stick to the thirtieth dilution as the proper dose in all cases is evident
from various passages in his writings.
 Thus, in the last edition of the Chronic Diseases, he directs that when a medicine requires to be
repeated it should invariably ge given in a lower dilution.
 Eg:s He says in the same work that nitric acid should be given for condylomata in the sixth dilution,
 thuja in the thirtieth, twenty-fourth, eighteenth, twelfth and sixth dilutions,
 petroselinum in drop doses of the fresh juice.
 In 1836 he writes to Dr. C. Hering (Hom. World, xxvi, 77) to send him the third trituration of
lachesis and crotalus.
 In 1841 he begs Dr. Lehmann, of Coethen, who prepared all his medicines, to send him the third
trituration of some medicines, a list of which he encloses (see facsimile letter, Lesser Writings).
 On the other hand, he seems also to have occasionally given medicines in higher dilutions (v. #287,
third note).
Potency
 In short, Hahnemann's practice shows great variations at
different periods of his life in respect of the doses he
gave.
 Generally, where he has previously used lower, he
subsequently gave higher dilutions, but that was not
always so, for he says in the first edition of the Chronic
Diseases that though he formerly gave the sixth
attenuation of stammum he now finds the third trituration
the best dose; and
 it is noteworthy that in the last edition of the Materia
Medica Pura, published in 1833, he gives as specimens and
models of homoeopathic practice two cases which had
already appeared in the first edition, published in 1816,
where the doses given were respectively the pure juice of
bryonia and twelfth dilution of pulsatilla".
248 Aph -Urgent case + no improvement=new remedy
 before the expiry of the period of action of a dose of medicine,
 the state of an urgent disease has,
 on the whole, not improved,
 but rather become aggravated - though may be only slightly - by
new symptoms,
 when, consequently the medicine has not been selected
homoeopathically corresponding to the case in its characteristic
effects,
 a dose of a medicine more precisely suited for the morbid state now
present must be given,
 even before the expiration of the period of action of the medicine
last administered".
 In chronic diseases –Same medicine
twice in succession –is improper
 Fourth edition.- "#250.
 Even in chronic diseases
 it is very seldom or never the case that nothing better can be
done, especially at first,
 than to prescribe the same medicine twice in succession, even
after the expiration of the period of action of the first dose; for
even when it has done good the improvement effected by it must go
on for some time, and usually there is no indication for the
repetition of the same medicine,
 WHAT CANNOT BE IMPROVED BY THE FIRST DOSE, A
SECOND OR LARGER DOSE IS EQUALLY UNABLE TO CURE".
Intercurrent remedy
 Third edition.- "#270.
 When, therefore, a thoroughly suitable specific
(homoeopathic) remedy cannot at once be found on
account of the deficiency of medicines whose pure effects have
been ascertained,
 there will usually be one or two next best medicines for the
characteristic original symptoms of the disease,
 one or other of which - according to the morbid state in each case -
may be useful as an
 So that its administration in alternation with the chief
medicine promotes the recovery much more palpably than giving
only the chief medicine, most, though still imperfectly, suited
amongst all those we possess, two or three times in succession".
Repetation =after expiry of the period of action
of the preceding dose
 "#271.
 The most beneficial procedure is to give solely and alone the best
adapted homoeopathic chief medicine in uninterrupted succession (in
which rare case it must correspond very closely to the chronic disease
 a smaller dose ought to be given every time, after the expiry
of the period of action of the preceding dose
 in order not to disturb the improvement
 (seeing that the medicine becomes ever less and less
necessary),
 To conduct the case to the desired end in the most direct and natural
way.
Retetation in chronic disease
272
 As soon as the chronic disease has for the time yielded to a
thoroughly suitable homoeopathic remedy,
 i.e. , specific or nearly specific for this case, if the disease is a very
chronic one (ten, fifteen or twenty years old),
 a dose of the chief remedy must be given for three or six months,
 at ever longer and longer intervals, at last at intervals of several
weeks (the intervals being varied according to circumstances),
 Always in smaller and smaller doses until all tendency of the organism
to the chronic dyscrasia has completely disappeared and is
extinguished
 The neglect of this provision leaves the best treatment incomplete
and in ill-repute".
273. Repetation=Orginal symptoms aggravate
Infirst 4 editions
The time for the repetition of the dose
The appearance of some slight traces of
one or other original symptom of the old
malady".
 To #252: In the first three editions the first part of this
paragraph runs thus:
 "But should we find that such ever-decreasing doses
do not suffice to attain the desired end, and that the
patient must continue to have equally large or even
larger and frequently repeated doses of the still
indicated homoeopathic remedy in order to avoid a
relapse, this is a sure sign, "..etc
 Idea seen in 215 of first edition
 To #253, note 2: Hahnemann generally uses the terms
"low" and "lowest" when he talks of increased degrees
of "dilution or attenuation", but the corresponding,
"potencies" he calls "high and highest".
Order of symptoms in proving corresponds to order in cure
Third edition - 279

 As some primary-action symptoms of medicines on the

healthy human body appear several days later than others,
 The corresponding symptoms in diseases cannot disappear
sooner than at this period of the treatment, even though
the other symptoms have yielded to the medicine; which is
not surprising". (1)
 FN: "For example, mercury, which exhibits its tendency to develop round ulcers
with elevated, inflamed, painful borders only after several days, in some persons
only after several weeks, can, on that account, when administered internally in the
venereal disease, cure the chancre only after the lapse of several days".
 280 – medicine of longer duration of action
and medicine of shorter duration of action

 If we have the choice, we should prefer for the

cure of chronic diseases medicines of longer
duration of action;
 for the cure of more rapid acute diseases- that is
to say, such diseases as have a tendency to change
their state frequently - medicines of short duration
of action".
 To #257: In the first edition "rational" is generally used in place of "true".
Solution
 Fourth edition.- 269
 acts most precisely and
As every medicine
effectually in solution,
 the sensible practitioner will give in solution
 (1) medicines which do not require to be administered in the
form of powder.
 (2) All other forms in which they have hitherto been used
(pills, electuaries, ..etc.) are to be rejected because the
action of the medicine on the living fiber is thereby rendered
uncertain and determinate". (3)
Dr Aegidi=mixing two highly diluted
medicines
 To #272 - 274: As the suggestion of Dr. Aegidi, Hahnemann
was induced to try the effect in diseases, especially
chronic ones, of mixing two highly diluted
medicines and giving them in one dose.
 He was at first greatly pleased with the results obtained,
and intended to recommend this plan in the fifth edition
of the Organon,
 but was dissuaded from this by some of the most
influential of his disciples; instead of doing so he merely
alludes to the proposal, mildly denouncing it in the note
to 272 5th edition FN
Excessive quantity of the medicine-increased
intensity of homoeopathic aggravation

 "#238. For if this greater alteration in the organism, caused by the excessive
quantity of the medicine, be too violent, owing to the dose selected being
stronger than necessary, though it may be very similar to the original disease,
besides the increased intensity of the homoeopathic aggravation (#157, fifth
edition), there ensues, at the very least, an unnecessary weakening after the
expiry of the period of action of the medicament, and, if the dose was very
excessive, there occur, in addition to the increased primary medicinal symptoms,
some symptoms of its secondary action, a kind of medicinal after-disease
opposite in character to the first".
large dose =serious ailments
239.
 Now, moreover, as scarcely any medicine can be selected so perfectly
homoeopathic that it shall correspond with mathematical accuracy and
completeness in every point to the totality of the disease symptoms (#156,
fifth edition), the new symptoms which, when the dose was suitably small,
were inconsiderable, are increased to serious ailments of many kinds if the
quantity of medicine given was excessively large".
Homoeopathic aggravation

 "#240. For these and other reasons the rational practitioner (who always
adopts the best method in his practice because it is the best, and does not
suffer himself to be deterred from doing so by the dictates of blind custom)
will select the remedy that is suitable for the disease in such a well-adapted
dose that it shall hardly be able to excite a semblance of aggravation of the
disease, that is to say, shall hardly be able to dominate in the slightest degree
as a counter-disease force over the disease to be cured".
 "#241. This apparent aggravation and increase of the disease under
treatment by the homoeopathic remedy should be scarcely perceptible, and
the only in the first two or three hours after its ingestion".
Smallest possible dose : minimum
aggravation
 242. One of the chief maxims of the homoeopathic medical system is the
following: The counter-disease force (the remedy), chosen as appropriate as
possible for the cure of the natural disease, should be made only strong
enough to effect our purpose, and should not injure the body in the least by
unnecessary strength".
 243. Now, as the smallest quantity of medicine naturally deranges the
organism least, we should choose the very smallest doses, provided always
they are a match for the disease".
size of the dose

 To #279: The corresponding aphorism in the first edition says with regard to
the size of the dose (#244)-

 "Hardly any dose of the homoeopathically selected

remedy can be so small that it shall not be stronger than the natural
disease, and that it shall not be able to overcome it".
 In the second and subsequent editions this aphorism is the same as we see in
the fifth edition, and differs from the first edition in that it makes the
diminution of the dose to be limited by its power of causing a primary
aggravation of the patient's symptoms.
Sensiveness of the organism to medicine is
increased if employed homoeopathically

 245.
 In diseases the sensitiveness of the organism to medicines, especially those
employed homoeopathically, is immensely increased.
 Of this the ordinary observer has no conception; it is only known to the careful
observer. It is beyond all belief when the disease has attained a great height". (1)
 Eg: Opium
 FN: "A patient struck down with typhus, insensible and comatose, with burning hot
skin bathed in perspiration, with stertorous respiration coming from his open
mouth in a jerky interrupted manner, ..etc. is restored to consciousness and in a
few hours to health by the smallest dose of opium, even if it be a million times
smaller than ever was administered by any physician in the world.
 Eg: Animal magnetism
Limitation up to 30th
 To # 280: The following note occurs here in the fourth edition. "My labours in
this matter, recorded in the prefaces to the medicines in the Materia Medica
Pura, have anticipated the wants of homoeopathic physicians, and saved
them the trouble of instituting thousands of trials on themselves by indicating
for some medicines the dilution required for homoeopathic practice; though
since then I have been constrained by more recent experience to carry the
dilution of most of the medicines still lower, in order to attain nearer to
perfection in this incomparable healing art, as will be found in the
introduction to the second part of my book on Chronic Diseases".
 This was of course written before Hahnemann had definitely fixed on
the thirtieth dilution as the most suitable dose for all medicines and
all diseases. In the places indicated in the earlier editions of the Mat. Med.
Pura he endeavours to fix the proper dilution for many of the medicines
which varies from the crude substance to the thirtieth dilution.
Criticising old school about crude combination of drug
 To #281: This paragraph is followed in the first edition by the subjoined note:
 "Let not the often enormous doses of medicines given in ordinary practice be urged against
this truth.
 These medicines have seldom any homoeopathic relation to the disease (when that is the case
the medicines are much more efficacious in altering the health than when they are given on
other principles).
 Moreover they are always given either in combination with other strong drugs, or other
violently acting medicines are given besides or between the doses of the first.
 Mixed up in this way each medicine can no longer exercise its peculiar action, but is altered by
the action of the second, third, or fourth ingredient.
 The so that they can often be taken without producing any great effect.
 A single one of these very powerful ingredients, if it be genuine and in full possession of its
powers, is given alone in the same dose would often cause death - a dreadful possibility,
 they are ignorant less dangerous by mixing a number of them together in one prescription. (This
proceeding seems to be vaguely indicated by the expression "corrigentia".]
 almost termed a piece of good luck that in ordinary practice may medicines, especially the
extracts, become almost absolutely powerless by the mode of preparing them hitherto in vogue
I cannot set forth in tabular form the weights and measures of the
medicines for the reason that the medicines differ so much in power.
 To #283: The degree of culture of their minds people have very different standards of
measurement for estimating the great and the small;
 Persons of such limited intelligence are to be met with who can appreciate nothing
that they cannot grasp with their hands, and who estimate things not according to
their real inherent power, but by their coarse commercial weight.
 The smallest weight of medicine they will hear of must be not less than a grain; a
tenth of a grain is for them an unconsidered trifle.
 How can we suppose that these people, with their restricted standard of
measurement, can have a conception of the necessary division and diminution of the
medicinal doses for homoeopathic purposes into smallest fractions of grains? It were
vain to expect it!
 Short-sighted man! how can you assign limits to the marvellous, almost spiritual
power of medicines? How with your coarse mechanical scales can you determine the
exact weight at which they will cease to have any effect?"
 Doctrine of divisibility
 "The doctrine of the divisibility of matter teaches us that
we cannot make a part so small that it shall cease to be
something, and that it shall not share all the properties of
the whole.
 And what is the use of larger doses of medicines if the smallest possible quantities given on the
homoeopathic principle suffice for the cure of diseases in the most rapid and permanent
manner? And why should there be doubts about the powerfulness of such small but still material
doses of homoeopathic remedies, though their calculated weight is extremely small,
 Imponderable
 the power of electricity and galvanism
 power of animal magnetism in altering man's health?
 the magnet
 north pole of a large magnet capable of lifting ten or twelve times its own weight
 experiments of trust, worthy observers on healthy persons have taught us (v. Andry and
Thouret, Beob. u. Unters. üb. d. Gebr. d. Magn., Leipzig, 1785, p. 155)" This is followed by the
subjoined paragraphs which appear in the first edition only:
248 DIVIDING THE DOSE

 Dividing the dose (giving it at several

intervals) has a much more powerful effect
than the whole dose administered all at
once".
249 DIVIDING DOSE
Eg:

 Eightdrops of the tincture of any medicine

in one dose have four times less effect than
these eight drops given in doses of one drop
at eight different times every hour or every
two hours".
250: Dilution

 If we employ dilution the dose

also (whereby
gains a greater capacity for expansion)
 we may easily produce an excessive effect;
 but the effect will be slightly different,
 whether the mixture with the diluting fluid is merely
superficial, or
 so uniform and intimate that the smallest part of the
fluid has become permeated with a proportionate part
of the dissolved medicine.
 The former will be much less powerful than the latter".
251 dilution + shaking + dividing dose
eg:

 Thus a single drop of the tincture

 intimately mixed by vigorous shaking
with a pound of water, and
 two ounces of it given every two
hours,
 will have four times as much effect as
eight drops given at once
252 : Mixture with larger volume of fluid

 The power of the fluid medicine is

considerably increased by its intimate
mixture with a larger volume of fluid
 In order to make the dose of the homoeopathic
remedy as small as possible, and as is
requisite,
 It must be given in the smallest possible volume,
 so as to come in contact with as few nerves as
possible when it is ingested". (1)
287 FN second note : Dilution beyond 30th
 This allusion to the employment of dilutions beyond the thirtieth occurs first in the fifth
edition.
 In the earlier parts of the second edition of the Chronic Diseases nothing is said about dilutions beyond
the thirtieth, which is recommended as the normal dose except when the medicine is repeated, when
less diluted preparations are advised. Thus after the thirtieth, then the twenty-fourth, then
the eighteenth, then the twelfth, sixth, and so on.

 But in the preface to the third part of the Chronic Diseases, published in 1839, there is an
approving allusion to the fiftieth dilution.
 (See the concluding paragraph of preface given above p. 296). In this passage Hahnemann departs from
the caution he gave in his letter to Dr. Schreter, of the 13th September, 1829 (see Brit. Journ. of Hom.,
v, p. 398):
 "I do not approve of your potentizing the medicines higher (as, for instance, up to thirty-six and sixty).

 There must be some limit to the thing; it cannot go on to infinity. By

laying it down as a rule that all homoeopathic remedies be diluted
and potentized up to thirty, we have a uniform mode of procedure in
the treatment of all homeopathists, and when they describe a cure we can repeat it,
as they and we operate with the same tools".
 Again, in 1832, when commenting on von Korsakoff's new-
fangled mode of attenuating drugs, Hahnemann says,
 "I must say that these procedures chiefly seem to show how
high one can go with the potentized attenuation of
medicines without their action on the human health
becoming nil.
 For this these experiments are of inestimable value; but, for
the homoeopathic treatment of patients, it is expedient in
the preparation of all kinds of medicines to remain
stationary at the decillionfold attenuation and
potency, in order that homoeopathic practitioners
may be able to promise themselves uniform results in
their cures". (Arch., xi, 2, 99).
292 FN- first edition- employment of other than
homoeopathic remedies
 indigestible or foreign or hurtful substances have been taken into the stomach or bowels.
Sometimes the employment of some undynamic remedies is needful.
 Such as fatty matters, which mechanically or physically loosen the connection and
compactness of the fibres; tannin, which solidifies the living fibres almost as much as it does
the dead fibres; charcoal, which diminishes the bad smell of unhealthy parts in the living
body, just as it destroys that of dead things; chalk, alkalies, soap and sulphur, which can
chemically decompose, neutralize and render innocuous the corrosive acids and metallic
salts in or on the human body;
 acids and alkalies which are able to dissolve different kinds of urinary calculi in the bladder;
the physically destructive red-hot iron, chemical escharotics of various sorts, ..etc.
Thank you