Pedia Tickler
Pedia Tickler
Pedia Tickler
Ascorbic acid
Drops 100mg/mL: Syrup: 100mg/ml
<3mos: 0.3ml/day 2-6y/o: 5ml/day
3-12mos: 0.6ml/day 7-12y/o: 10ml/day
1-2y/0: 1.2ml/day
Vit. B complex + hysine + beclizine (Appebon
syrup)
2-6y/o: 1-2tsp OD
7-14y/o: 2-4tsp OD
Iron wtx5/elem Fe
1mkday OD- prophylactic Hemarate 30/5
3-6mkday BID-therapeutic Iberet 26.25/5
Zinc RD – 10-20mg/day Incremin 30/5
10mgdrops- infant Sangobion 12/10
20mg- >2yo Ferlin 30/15
Folic acid
2.5g/ml
0.2 mkday
Vitamin A
6-11mos: 100,000IU – 1 dose
12-71mos: 200,000IU
<2yrs: drops
10mg/ml=1ml
>2yrs: syrup
20mg/5ml= 5ml
Analgesics/Antipyretic
Paracetamol (Q4h) Mefenamic Acid (q6-8hr)
RD: 10-15mkdose PO RD: 5-8 mkdose
10mkdose IV Susp: 50mg/5ml
15mkdose-BFC 125mg/5ml
Drops: 100mg/ml Cap: 250mg/500
60mg/0.6mk
Syrup: 120mg/5ml Aspirin (Q4-6H)
125mg/5ml RD: 10-15mg/kg/dose
350mg/5ml upto
Tab: 325mg/tab 60-80mg/kg/24h
250mg/tab Anti-inflam:60-
500mg/tab 100mg/kg/24hPO
Amp: 150mg/ml Kawasaki: 80-100mkday
300mg/ml
Nimesulide (BID)
RD: 2.5-5mkdose
100mg/tab
Ibuprofen
RD: 5-10 mg/kg/dose
PO Q6-8H
Susp: 100mg/5ml
Forte: 200ng/5ml
Cap: 200mg
Antacids
Ranitidine (Q8h-12h) Famotidine (Q12h/IV-
Q8h)
RD: 0.75mkose PO RD: 0.2mkdose
0.8-1mkdose IV Amp: 25mg/2ml
Amp: 25mg/ml, 50mg/5ml Tab: 20mg/40
Tab: 150mg/300mg
Cimetidine (Q4-6h) Omeprazole
RD: 10-15mkday 1mgkday
<1y.o: 20mkday
1-12y.o: 20-25mkday
Liquid: 100mg/5ml
Amp: 150mg/ml, 100mg/ml
Tab: 200mg, 400mg
AlMg (Maalox) (Q6h) Ursofalk
2-4 tabs max: 16tabs 10-15mkday
*take 30 minutes 1 hr 200/5ml
after meal at bedtime
Susp: 180ml; 355ml
Tab: chewable
Fw/flatulence-
Almg+dimeticone (Maalox
plus)
Anti-emetic/ Anti-spasmodic
Metoclopramine Nifuroxide (Ercefuryl)
RD: 0.5mkdose PO <6mos- 10ml
0.2mkdose IV >6mos- 5ml
Amp: 10mg/2ml, Adult: 1cap Q6H
5mg/2ml Susp: 220mg/5ml
Syr: 5mg/5ml Cap: 200mg
Tab: 10mg
Dicycloverine HCL Hyosciene N-Butyl
(Q8h) (Bromide) Q6-8h
RD: 2.5-5mg/kg/day RD: 0.15mkdose
6mos-2y.o: 0.5-1ml Amp: 20mg/ml
2y.o-5y.o: 2.5-5ml Tab: 10mg
Drops: 5mg/ml,
15mg/ml
Syr: 2mg/ml, 10mg/ml
Tab: 10mg
Domperidone (Motilium)Q8h*15
RD: 0.3mkdose
Dyspepsia: Adult: 1tab/2tsp Q8h
Children: 2.5ml Q8h Suspension: 1mg/ml
Tab: 10mg
N/V: Adult: 2tab/4tsp Q6-8h
Children: 5ml Q6-8h
Dyspepsia N/V
10kg 2.5ml 5ml
20kg 5ml 10ml
30kg 7.5ml 15ml
Anti-Diarrheals
Paroromycin (Humagel) Erceflora – Bacillus
clausii
RD: 20-30mkday 3-4 dived >1mos: 1-2 vials/day
dose 2-11y.o: 1-2
150mg/cap, 150 vials/day
mg/5ml Adult: 2-3 vials/day
Racecadotril (Hidrasec) Nifuroxamide
(Ercefuryl)
1 mos onwards <6mos: 1tsp BID
RD: 1.5mg/kg/day Q8h >mos: 1tsp TID
BW Hidrasec
Sachet
<9kg 10mg 1
sachet
9-13kg 10mg 1
sachet
13-27kg 30mg 1
sachet
>27kg 30mg 2
sachet
Adult dose: 100mg/cap
Q8h
Antihelminthics
Mebendazole
500mg/tab single dose
100mg/tab or 5ml BIDx3 consecutive days
20mg/ml susp: 5ml BIDx3 consecutive days
50mg/ml susp: 10ml SD
Enterobiasis (100mg or 5mg SDrpt 2 or 4 weeks)
Susp: 20mg/ml, 50mg/ml
Tab: 100mg; 500mg
*deworm @2-4 yrs old
Pyrantel Pamoate
RD: 10-20 mkdose
Susp: 125mg/5ml
Tab: 125mg; 850mg
Albendazole
RD: 75mkday
Susp: 200mg/5ml
Tab: 400mg
Quinolones
Ciprofloxacin - BID
Vial: 100mg/50ml, 200mg/100ml, 400mg/200ml
Amebicide
Metronidazole q6h Furazolidone
RD: 30-50 mkday PO RD: 4-7 mkday
7.5 mkdose IV Liquid: 16.7 mg/5ml
15mkdose – loading Susp: 50mg/ml
dose
Vial: 5mg/ml
IV: 500mg/100
Susp: 125mg/5ml
200mg/5ml
Paramomycin Etofamide (Kitnos)
RD: 20-30 mkday RD: 15-20mkayX3 days
Susp: 150mg/15ml Q12H
Susp: 100mg/5ml
Tab: 200mg; 500mg
Antihistamine
Hydroxyzine Hcl Desloratadine (Aerius)
(Iterax)
Q12h x 5 days 6-11 mos: 2ml
RD: 1mg/kg/day or wt/4 1-5 y.o: 2.5 ml
Syrup: 2mg/ml 6-11y.o: 5ml
Tab: 10mg; 25mg >/=12y.o: 10ml
Amp: 5mg/ml Syr: 2.5ml/5ml
Tab: 5mg
Chlorphenamine Maleate Diphenhydramine Hcl
Q8h RD: 3-5 mkdose PO
RD: 0.2mkdose 1mkdose IV
Amp: 10mg/ml Syr: 12.5mg/5ml
Vial: 10mg/ml Cap: 25mg, 50 mg
Syrup: 2mg/5ml IV/IM: 50mg/ml
Tab: 4mg
*20kg-1/2 amp IM
>20kg-1amp IM
Cetirizine diHCL-OD-BID Levocetirizine
RD: 0.25-0.27 mkdose 0.125mkdose
Drops: 10mg/ml
2.5mg/ml
Soln: 1mg/ml
Sry: 5mg/5ml
Tab: 10mg
Mucolytic
Carbocysteine (Q8-12h) Erdosteine (Q12h)
RD: 30-50 mkday RD: 10mkday
Drops: 50mg/5ml 10-20kg, 2-6y.o: 2.5ml
Syr: 100mg/5ml 21-30kg, 7-12y.o: 5ml
Cap: 500mg >30kg, >12y.o:
<3mos: 0.25ml 5mlTID/7.5ml BID
3-5mos: 0.5ml Susp: 115mg/ml; cap:
6-8mos: 0.75ml 300mg
9-12mos: 1 ml
5y.o: 5ml
Ambroxol (Q8h)
D: 1.2-1.8 mkday
Liq: 15mg/5ml; 30mg/ml
Soln for inhalation:
15ml/2ml
Amp: 15mg/2ml
Ped drops: 6mg/ml
Tab: 30mg; retard cap
75
Bronchodilators
Salbutamol TID Procaterol
RD: 0.13-0.15 mkdose >/6: 5ml
Sry: 2mg/5ml </=5y.o: 2.5ml
100mg/5ml
Amp: 1mg/ml Bambuterol
Tab: 2mg
Terbutaline BID TID 6-12y.o: 5mkdose
1-15y.o: 2.5ml Oral soln: 1mg/ml
<3y.o: 0.075mkdose Tab: 10mg
Syr: 1.5mg/5ml
Soln: 2.5mg/5ml Aminophylline/Theophyline
Amp: 0.5mg/ml
Tab: 2.5mg 3-5mkdose
80mg/5ml; 125mg/tab,
175mg/tab
Cephalosporins
1st generation
Cefalexin Q6h Cefuroxime Q6-8h
RD: 30-50 mkday PO RD: 20-40mkday PO;
50-100mkday IV 50-100mkday IV
Drops: 100mg/ml
Susp: 125mg/ml Cefamandol
250mg/ml RD: 50-100mkday
Cap: 250mg; 500mg
Cefprozil
Cefazolin RD: 20-4-mkday
RD: 50-100mkday IV Powder: 125mg/5ml;
x 3dose 250mg/5ml
Vial: 250mg Tab: 250mg; 500mg
Inj: 500mg; 1g
Cefotiam
2nd generation RD: 50-100mkday
Tab: 200mg
Cefaclor Q8h Vial: 0.5g; 1 gm
RD: 20-40mkday
Drops: 50mg/ml Cefixime Q12h UTI: 8
Susp: 125mg/5ml TF: 20
250mg/5ml RD: 3-6mkday PO,
Tab: 315mg; 750mg 15mkday
Cap: 500mg Drops: 20mg/ml
Susp: 100mg/5ml
Cap: 100mg;200mg
Cefdinir
RD: 9-8mkday
Cap: 100mg
Nifedipine Q4-6h
RD: 10mkdose
Max: 10mg/kg/24h
Spironolactone
1.3-3mkday QID PO
Antifungal
Nystatin Q6h Fluconazole – OD
Adult & children: RD: 3-6mkday
4-6ml Vial: 3mg/ml
Infant: 2ml Cap: 50, 150, 300mg
Tab: 500,000 U
Susp:100, 000 U/ml Griseofulvin
Tab: 125mg/500mg
Macrolides
Erythromycin q8h Azithromycin OD-BID
RD: 35-50mkday RD: 15-20mkday
Granules: Susp: 200mg/5ml
200mg/5ml; Tab: 250mg; 500mg
400mg/5ml Vial: 500mg
Drops:
100mg/2.5ml Chloramphenicol q6h
Tab: 250-500mg RD: 50-100mkday;
75mkday (enteric
Clarithromycin fever)
Q12h FT infant>/=2week: 25-
RD: 7.5mkdose; 50mg/kg/day
15mkdose
Susp: 125mg/5ml Cotrimoxazole BID
Tab: 250; 500mg RD: 5-8mkday; 8 UTI;
10 BPN
Roxithromycin OD- Susp: 200mg/40mg/5ml-
BID (40mg/5ml) (wt/2)
Adult: 400mg/80mg/5ml-
150mg/tab; (80mg/5ml)(wt/4)
300mg/tab Q12h Tab: 400mg/80mg;
Children: >40kg 800mg/100mg
Kiddie tab: 100mg
Anti- TB drugs
Anticonvulsants/ Sedatives
Phenobarbital Midazolam
LD: 10mkday RD: 0.2mkdose
MD: 5mkdose (max Tab: 15mg
25mkdose) Amp: 5mg/ml, 5/5,
15/3
Diazepam Phenytoin
RD: 0.2-0.8 mkdose LD: 10mkdose
MD: 5mkday
Susp: 30/5, 12/5
Cap: 30, 100
Steroids
Prednisone – BID Dexamethasone
RD: 1mkday BID; RD: 0.5 – 1mkdose
2mkday OD 0.3mkdose
Susp: 10mg/5ml initial, then 0.1
Syr: 5mg/5ml; mkdose 1-2mg/kg
20mg/5ml Q6h x 4
Tab: 1, 5, 10, 20, *xtubate on 3rd dose
30, 50mg
Hydrocortisone Procaterol (Meptin)
RD: 5mkdose Q6-8h BID-TID
LB: 10mkdose RD: 0.25mkdose or
MD: 5(max 100) 0.25xwt
Vial inj: 100mg; Syr: 5meq/ml
250mg; 500mg Tab: 25meq, 50meq
Erdosteine Aminophylline
(Ectrin/Zertin) LD: 5-7mkdose
175mg/5ml-10mkday MD: 3-5mkdose
BID;
300mg/cap BID
Combivent: 200ug Ipatropium
<2y.o: 5-8 drops; 2-3 y.o: 3 drops; >4y.o: 20
drops
IVIG
Dose: 2g/kg in 12H or 400mg/kg/dose x 5d
2.5g/vial, dilute w/ 50ml diluents to make
50mg/ml administer the ffL
Test dose:
0.1 0.5ml/kg/H x 15min
NAHCO3
0.2 1ml/kg/H x 15min BE x wt x 0.3 or
0.4 1.5ml/kg/H x 15min 1meq/kg can be given IV
0.8 2ml/kg/H x 15min push or drip 50mcg/kg
2.5ml/kg/H x 15min NA>1-2 meq/kg
3ml/kg/H x 15min
3.5ml/kg/H x 15min
4ml/kg/H x 15min
*if tolerated in fuse the rest at ____cc/h for 10hr
watch out for headache, flushing, hypotension,
fever and chills
Aminosteril
0.5/kg-inc until 3g/kg
Wt x RD x 100/6%/24 or wt x RD/0.694
*start 1g x 48H then resume at 2g
Conversion of Hyponatremia
1ml=2.5 meqs NaCL
Wt: 1.8 kg
S.Na: 131.4
D-A x wt x 0.6 (140-131.4 x 1.8 x 0.6 = 9.2 meqs)+
wt x 3= maintenance (1.8 x 3=5.4)
1st Shift
HYOPCALCEMIA
D5W- 6.6 K/K (?) – 0.1 to 0.3 meqs/k/H
D5IMB- 50 NK of Body= 50meqs
NaCl- 2.5 (?) K/R –meqs KCL/#Hrs/wt
Hypokalemia
D-A x wt x 0.3 + (Wt x 2) ?
Wt x 0.2 x 8 x 3 x 2 x wt
Sk- <3-5% -0.05
<2.5-10%-0.10
Wt X 0.05 x 50 /wt x (2/maintenance)
RESPONSE TO PHOTOTHERAPY
*check rebound B2 for 12-24H after discharge
CARDIAC OUTPUT
Newborn: 180-240ml/kg/min or 4ml/beat
DOPAMINE DRIP
(200mg/250-800conc) 0.0375/26.6
(400mg/250ml-1600conc) 0.075/13.3
Wt x RD x 60 (0.075)
LEVOPHED
4mg/4ml; 2mg/ml
e.g 2ml/ml
2/100 x 1000= 20 conc
DRIP FORMULA
6 x wt (kg)x mcg/kg/min – mgin100ml of D5NSS
MI/H
ISOPROTERENOL/EPINEPHRINE/NOREPINEPHRINE
0.6 x wt (kg) = mgin100ml O
*1ml/H will deliver 0.1 mcg/kg/min
DOPAMINE/ DOBUTAMINE
6 x wt (kg) = # mg to add to diluents to make 100ml
volume
DOBUTAMINE DRIP
2.5 – 15mcg/kg/min (max: 40mcg/kg/min)
Peak effect: 10-20min
Prep: 12.5 mg /ml x 20ml/vial= 250mg/250ml (vial)
Premix: 1000mcg/ml in 250= 250/250 (1mg/ml)
2000mcg/ml in 250 ml= 500mg/250 (2mg/ml)
Dobu-premix
0.06-1000=250/250
D%W
0.03-2000
Wt x dose x
0.06/0.03
Wt x RD x 60 or wt x RD x 1400/12500 or 6 x wt in kg=
____mg in
2000
100ml(1mcg/kg/min)
Ex: 250mg in D5W 250cc(1mg/ml) 500mg in
D5W250cc(2mg/ml)
Mcgtt/min= (Wt x DD)/16.6 ugtts/min=(wt x
DD)/33.2
= Wt x DD x 0.06 = Wt x DD X 0.03
*to check: 7.5 – actual x 2000/ 60 /wt
actual x conc/60/wt
FUROSEMIDE DRIP
20 mg/2ml
**4ml + 20cc PNSS to run @ 1cc/h
(wt)15 x (dose) 0.1 x 24
36 x 2/20 = 3.6
3.6/4ml = 0.9 or 1cc
EPINEPHRINE DRIP
Wt x 0.6 mg = mg added to 100mgD5W
1cc/H = 0.1 ug/kg/min
5cc/H = 0.5 cc/min ml/H= wt x dose x 60
10cc/H = 1mg/kg/min conc
0.1mkd/0.1cc/kg/dose
INSULIN DRIP
0.1 – 1 cc or ml/H
Wt x 0.1 x 24 = # of ml/cc of insulin to be added
to NSS to make 24 ml soln to run for 24H
MIDAZOLAM DRIP
Prep: 5mg/ml amp
Dose: intermittent: 0.05 – 0.15mg/kg/dose
Continuous: 1-2mcg/kg/dose
AMIODARONE DRIP
Prep: 50mg/ml amp
Dose: infant and child: 5mg/kg over 30 min ff by
infusion starting at 5mcg/kg/min
Max dose: 10mcg/kg/min or 20 mg/kg/H must be
diluted in D5W
infusion concentration should not
exceed 2 mg/ml
wt(kg)x dose x 60 x 50 = mg in 50mlD5W
1000
To make: 1ml/H= 1mcg/kg/min
INSULIN DRIP
Prep: 1U/ml amp
Dose: Infant and Child 0.1Ukg/H (titrate to
clinical effect)
Glucose drop: 80-110mg/dl/H
NICARDIPINE DRIP
Prep: 2.5mg/ml= 5mg/10ml ampule
Dose: Child: 0.5-5mcg/kg/min (titrate to clinical
effect)
Adult: start with 5mg/H, increase dose as
needed by
2.5mg/H Q 5 -15 min (Max dose: 15mg/H)
decreased by
3mg/H as needed to maintain desired response
AMINOPHYLLINE DRIP
LD: 5mg/kg BW in 30cc 5W in a soluset (if px is not
maintained
on oral theophylline) or
25mg/vial dilute 1ml + 4ml NSS to make 5 mg/ml
so;ution.
Aspirate ____mL give per iv infusion for 30 min
as LD
(5mg/kg)
D5W250cc + Aminophylline 250mg/amp at ____ugtts/min
COMPLICATIONS:
Vascular embolism
Infection
Cardiac arrhythmia vol overdose
CP arrest
Electrolyte imbalance
Neurotoxicity
Cisplatin – ototoxocity, p. neuropathy
Paclitaxel – p. sensory, neuropathy
Vinca Alkaloids- motor , sensory,
autonomic neuropathy, adynamic ileus,
urinary bladder atony
Cardiac Toxicity
Doxorubicin, Daunomycin – cardiomyopathy
Pulmonary Toxicity
Bleomycin – interstitial
Alkylating agent pneumonistis w pulmonary
fibrosis
Gastrointestinal Toxicity
Mathotraxate – hepatic fibrosis
Vinca Alkaloids- adynamic ileus, urinary
bladder atony
Genitourinary Toxicity
Cisplatin – azotemia, Mg wasting
Methotrexate – oliguria RF
Cyclophosphamide/ Ifosfamide – chronic
hemorrhagic cyctitis
Dermatologic Toxicity
Doxorubicin Skin necrosis,
sloughing
from
Actinomycin – D drug extravasation
Vincristine
Gonadal Dysfunction
Azospermia recovery is uncommon
Hematologic toxicity
Granulocytopenia/neutropenuia
- 6-12 days after administration
- Recovery in 21-24 days
ANC= (WBC count)(%segmenters)
- Must be ≥ 1500 for chemo to proceed
Thrombocytopenia
- Recovers 4-5 days later than
granulocytes
- ≥ 100,000/mm3 for chemo to proceed
Absolute Contraindications to BF
Galactosemia
Tyrosinemia
Relative Contratindications to BF
Psychosis
Active TB
WATERLOW CLASSIFICATION
WT for Age: Actual WT x
> 90 no PEM
100%
75-90 MILD
Wt at P50
60-74 MODERATE
<60 SEVERE
HT WT
>95 - no stunting >90 – no wasting
90-95 –mild 80-90- mild
85-89- moderate 70-80- moderate
<85- severe <70- severe
ET SIZE BY AGE
Premature 2.5mm
0-3 mo 3.0mm
3-7 mo 3.5mm
7-15 mo 4.0mm
15-24 mo 4.5mm
2-10 yrs Age (yrs)+16/4 or Age(yrs)+ 4/4
10-20 yrs 6-8mm
Laryngoscope Blade
Size
Term/Newbor Size 1
n
2-11 yrs Size 2
>12yrs Size 3
Electrolyte Computation:
I. Potassium
N= 4-5.6 meq
N K deliuence: 0.1-0.4meq/kg
Deficit = (KD - KA)x wt x 0.6
Maintenance K: 2 x wt
Total K deficit: deficit + maintenance
Full Incorporation: 40meq/L or 20 meq/500cc
K infusion rate:
N= 0.2meq – 0.4meq/kg
IV rate x amt of K (meq)
Vol of IVF x Wt
Deficit: Wt x 50 x __K__
Maintence – 2 x wt
Creatinine Clearance:
1. Based on ht
*0.33 = pretem; lbw, <1 yr
0.45 = term, infant, <1yr
0.55 = children, adolescent female
0.7 = adolescent male
* X ht (cm)
Serum creatinine(mg/dl)
2. Adult *male: 72
Female: 85
140-age x wt
* x Creatinine (mg/dl)
Values:
80-120: normal
50-80: renal impairment
20-50: renal insufficiency
5-20: renal failure
<5: uremia
PHOTOTHERAPY
Indication: PT 10mg% Bilirubin
PT 15mg% Bilirubin
Kramer’s Classification
ZONE JAUNDICE EST. LEVELS
1 Head/neck 6-8mg/dl
2 Upper trunk 9-10mg/dl
3 Lower trunk to thigh 12-14mh/dl
4 Arms/legs/elbow/knees 15-18mg/dl
5 Hands/feet >18mg/dl
B1 – uncongugated/ indirect
B2 – conjugated/ direct Bilirubin
CREATININE CLEARANCE*
(140-age) (wt in kg) x 0.85 (F) 1(m)
Creatinine (mg/dl) x 72
* ÷ 88.4 → mg/dl
STAGING
1 Kidney damage with >90
NGFR
2 Mild ↓ GFK 60-90
3 Moderate ↓ GFK 30-59
4 Severe ↓ GFK 15-24
5 Kidnet failure <15
DEFICITS
Na= 135-150/3-4meq/kg/day
Na deficit= (Desired 140-actual) X TBW
TBW (L)= 0.6 x BW (kg) + Maintenance
FFP- 20cc/k
PLT conc- 1 uint/10kg
TPR
BP
02 stat
SCE, CBS
(-)DOB
CP status assessed, may transfuse 1 unit PRBC,
type-specific, after proper reverse typing x 4hrs.
Monitor VS q 15mins on the 1st hr then q30mins
thereafter once stable ↓ IVF rate to ___ cc/hr (or
KVO) watch out for any BT reactions
Refer PRN
Thank you
PPE: awake, conscious, not in CPD, anicteric
sclera, pinkish conjunctivae, non hyperemic, non-
enlarged tonsils, (-) CLAD, (-)NVE
SCE, CBS
AP, NCRRR (-)murmur
Flat, soft, NABS, Nontender, tympanitic, grossly N
ext, full pulses CRT < 2 sec.
Albumin Transfusion
Wt x 1cc x 50% = amount in CC
Kg 12.5
KAWASAKI DSE
Fever= 5 days
1. Bilateral bulbar conjunctival injection
with limbic sparing (-)exudates
2. Erythematous mouth and pharynx, strawberry
tongue, red, cracked lips
3. Polymorphous, generalized erythematous
rash
4. Changes in peripheral extremities
consisting of induration of hands and feet
5. Acute nonsuppurative cervical
lymphadenopathy (uni/bilateral) ~1.5 cm
MENINGITIS
<1mo: GBS, enterobacteriaceae, listeria,
monocytogenes
Tx: Ampicilin & Cefotaxime
Alt: Ampicilin & gentamycin
(nosocomial- Ampi + gentamycin)
AMINOSTERIL COMPUTATION
Wt x 1gm x 100 = ___ cc to run for 22hrs, rest for
4hrs
6
EX. Wt: 900gms 0.9x 1gm x 100 = 15cc
6
1. Order: Aminosteril 6% 15cc to run for 22 hrs;
rest for 4 hrs x 2 cycles
(TFI 150- 1gm AA - FFP)
ex: FFP x 2 units 18cc/unit
150-15cc-15cc-18cc+18cc x wt = 84 ÷ 24 = 3-4cc/hr
IVF rate
24H
CEFEPIME
Term and preterm infants greater than 28 days
of age: 50mg/kg per dose every 12 hrs
Term and preterm infants 28 days of age and
younger: 30 mg/kg per dose every 12 hrs
Meningitis and severe infections due to
Pseudomonas aeruginosa or Enterobacter spp:
50mg/kg per dose every 12 hrs
Administer via IV infusion by syringe pump over
30 minutes or IM.
To reduce pain at IM injection site, cefepime
may be mixed with 1% Lidocaine without
epinephrine
CEFOTAXIME
50 mg/kg dose IV infusion on syringe pump over 30
minutes, or IM.
Dosing Interval Chart
PMA (Weeks) PostNatal (day) Interval
(hours)
≤29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
> 7 8
≥45 All 6
Disseminated Gonococcal Infections: 25 mg/kg per
dose IV over 30 minutes or IM every 12 hrs for 7
days with a duration of 10 to 14 days if meningitis
is documented.
CEFTAZIDIME
30 mg/kg per dose IV infusion by syringe pump
over 30 minutes or IM.
To reduce pain at IM injection site,
Cfetazidime may be mixed with 1% Lidocaine
without epinephrine.
Dosing Interval Chart
PMA (Weeks) PostNatal Interval
(day) (hours)
≤29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
> 7 8
≥45 All 6
RANITIDINE
Oral: 2mg/kg per dose every 8 hrs.
IV: Term: 1.5 mg/kg per dose every 8 hours slow
push
Preterm: 0.5 mg/kg per dose every 12 hours slow
push
Continuous IV infusion: 0.0625 mg/kg per hour; dose
range. 0.04 to 0.1 mg/kg per hour
FLUCONAZOLE
Invasive Candidiasis: 12 to 25 mg/kg loading
dose, then 6 to 12 mg/kg per dose IV infusion
by syringe pump over 30 minutes or orally.
Consider the higher doses for treating severe
infections or Candida strains with higher MICs
(4 to 8 mcg/ml). Extended dosing intervals
should be considered for neonates with renal
insufficiency (serum Creatinine greater than
1.3 mg/dl)
NOTE: the higher doses are based on recent
pharmacokinetics data but have not been
prospectively tested for efficiency or safety
Prophylaxis: 3 mg/kg per dose via IV infusion
twice weekly or orally. A dose of 6 mg/kg twice
weekly may be considered if Candida strains
with higher MICs (4 to 8mcg/ml). Consider
prophylaxis only in VLBW infants at high risk
for invasive fungal disease.
Thrush: 6mg/kg on day 1 then 3mg/kg per dose
every 24 hrs orally.
OXACILLIN
Usual Dosage: ____mg/kg per dose IV over at least
10 minutes
Meningitis: 50 mg/kg per dose
DOSING INTERVAL CHART
PMA (Weeks) PostNatal Interval
(day) (hours)
≤29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
> 7 8
≥45 All 6
MEROPENEM
Sepsis: 20mg/kg per dose IV
Less than 32 weeks GA: less than or equal to 14
days PNA, every 12 hrs, greater than 14 days PNA,
every 8 hrs
32 weeks and older GA: less than or equal to 7 days
PNA, every 12 hours; greater than 7 days PNA, every
8 hours
Meningitis and infections caused by Pseudomonas
species, all ages: 40mg/kg per dose every 8 hours.
Give an IV infusion over 30 minutes, longer
infusion times (up to 4 hrs) may be associated
with improved therapeutic efficacy.
METRONIDAZOLE
Loading dose: 15mg/kg orally or IV infusion by
syringe punp over 60 minutes
Maintainance dose: 7.5 mg/kg per dose orally or IV
infusion over 60 minutes. Begin one dosing interval
after dose.
10 x 8 ÷
24 = 3 [IVF – 3 = 8]
15 x 8 ÷
24 = 5 [IVF – 5 = 6]
20 x 8 ÷
24 = 6 [IVF – 6 = 5]
30 x 8 ÷
24 = 10 [IVF – 10 = 1]
feeding q3H → 24h ÷ 3h = 8
DC CBG monitoring once 20cc feeding is
tolerated.
BICARBONATE CORRECTION
(15 – initial HCO3) x Vol x Kg BW
FLUID LIMITATION
EPINEPHRINE DRIP:
6 X Wt in Kg x mcg/K/min = ____mg in 100ml of
D5W/NS
mL/Hr
Set your own rate: ex: 4ml/hr
6 x wt x 0.1 mcg/kg/min
4ml/h
If wt is 40 kg: 6 x 40 x 0.1 = 6mg in 100ml D5W
4
Order: Start epinephrine drip: 6mg epinephrine
+ 100cc D5w x 4cc/Hr (0.1 mcg/k/min)
BEVV
BEVV x 0.6 x Wt
- (1/2 push then ½ to run for _____) or
- Desired –actual x 0.3 x wt
DRUGS RD PREPARATION
Tab: 30mg,
1.2 – 1.6
Ambroxol Syr: 15mg/ml
mkdose(BID-TID)
Drops: 6mg/ml
Amikacin
10mkdose (LD) Amp/Vial:
(Amikin,
15mkdose (MD) 50mg/mlx2ml
Amikacide,
15mg/kg/day (BID) 250mg/mlx2ml
Onikin)
Cap: 250mg;
500mg
Syr:
Amoxicillin 250mg/5ml,
30-50 mkday (TID)
(Pediamox) Ped drops:
125mg/1.25ml,
100mg/ml
Vial: 500mg
Amphotericin 50-100mkday (IV), Vial:
B 30-50mkday (PO), 50mg/10ml
1mg/kgBW (alternate
day)
Cap: 250mg;
500mg
Syr:
125mg/5ml,
50-100mkday (IV),
Ampicillin Forte Syr:
30-50mkday (PO),
(Ampicin, 250mg/5ml,
1mg/kgBW (alternate
Pensyn) Ped Drops:
day)
125mg/1.25ml,
100mg/ml
Vial: 500mg
Tab: 4mg,
Amp: 5mg/ml
Antamin 0.2-0.3mkdose Vial:
5mg/mlx10ml
Syr: 2mg/5ml
Tab: 375mg;
625mg
Susp:
156.25/5ml;
20-40mkday (BID- 228.5/5ml;
Augmentin
TID) 312.5mg/5ml;
457mg/5ml, IV
Vial: 300mg;
600mg
Tab: 1g
Tab: 250mg.
500mg
ASA 75-100mkday (TID)
Enema: 4mg
Susp: 250mg
Aztreonam 30-50mkday
Cap: 25mg,
3-5mdose (PO TID- 50mg
Benadryl QID) Syr:
1mkdose (IV OD) 12.5mg/5ml
Inj: 50mg/ml
0.01mkdose q6h Tab: 10mg
Buscopan
0.02-1.5mkday Amp: 20mg
Cap: 500mg,
Carbocistein 10-20mkday(infant)
Syr: 100mg/5ml
e (TID-QID)
Susp: 250mg/ml
Caterizine 0.25mkday
Cap: 250mg,
500mg
Cefaclor 20-40mkday (TID) Susp:
125mg/5ml,
250mg/5ml
Cap: 500mg
Cefadroxil 25-50mkday (TID)
Syr: 125mg/5ml
Cefetamet 20mkday (BID)
Cefotaxime 50-100mkday (BID) Vial: 1g
Vial: 500mg;
Cefepime 50mkday q 8h
2g
Vial: 500mg;
Ceftazidime 50-100mkday
1g
Vial: 500mg;
Cefazolin 50-100mkday
1g
Vial: 250mg,
50-100mkday (TID- 500mg, 1mg
Ceftriaxone
QID) plus 10ml
diluent
Tab:
500mg/500mg
Susp:
50-100mkday (IV); 125mg/5ml,
Cefuroxime
20-40mkday(oral) 250mg/5ml
Vial: 250mg,
750mg,
1.5g
Cap: 250mg,
30-50mkday (PO), 500mg
Cefalexin
50-100mkday (IV) Susp:
125mg/5ml
Drpos:
100mg/ml
Cap: 250mg,
500mg
Chlorampheni
50-100mkday Susp:
col
125mg/5ml
Vial: 1g
Cap: 250mg,
400mg
Syr: 100mg/5ml
Cimetidine 50-100mkday
Amp:
200mg/2ml,
300mg/2ml
Tab: 250mg,
Ciprofloxaci
500mg
n 7.5mkday (BID)
Susp:
(Klaricid)
125mg/5ml
Cap: 250mg,
500mg
Cloxacillin
50-100mkday (BID) Oral soln
(Pharex)
powder:
125mg/5ml
Tab:
400mg/80mg;
Cotrimoxazol
8-12mkday (BID) 800mg/180mg
e
Susp:
200mg/40mg/5ml
Tab: 2mg, 5mg
Diazepam 0.2mkdose
Amp: 10mg/ 2ml
Cap: 50mg;
Diflucan 6-13mkday 150mg; 250mg
Vial: 2mg/ml
Tab: 500mg
Diloxanide 20mkday (TID) Susp:
125mg/5ml
Doxycyxline 204mkday Cap: 100mg
Cap: 250mg;
Erythromycin 30-50mkday
500mg
Susp:
200mg/5ml;
400mg/5ml
Drpos:
100mg/2.5ml
Tab: 400mg;
Ethambutol 15mkday
200mg
Cap: 250mg
Ferrous 1mkday (MRD)4- Syr: 220mg/5ml
Sulfate 6mkday (Txc) Drops:
75mg/0.6ml
LD:12-20mkday
Fluconazole
MD: 6-12mkday
Tab: 100mg
Furazolindon
4-7mkday Amp: 50mg/5ml
e
Tab: 20mg,
Furosemide 0.5-1mkdose 40mg
Amp: 10mg/ml
Vial: 40mg/ml;
Gentamycin 5-8mkday
80mg/2ml
Tab: 25mg
Hydralazine 0.15mkdose (IV)
Amp: 20mg/2ml
Vial: 259mg
Hydrocortiso
5mkdose Amp: 100mg,
ne
250mg, 500mg
0.01mkdose; 0.02- Tab: 100mg;
Hyoscine
0.15mkday Amp:20mg
Tab: 200mg;
Ibuprofen 5-10mkdose 400mg; 600mg
Syr: 100mg/5ml
Tab: 300mg
INH 5-10mkday (Premeal)
Syr: 100ml/5ml
Tab: 500mg
Isoprinosine 50mkday
Syr: 250mg/5ml
Meclizine 12.5-50mkday
Mefenamic Cap: 250mg,
6.5mkdose (Q6h)
Acid 500mg
Susp: 50mg/5ml
Meperidine 6mkday; 0.5mkdose
Syr: 5mg/5ml
Amp: 5mg/ml,
Metocloprami 0.25mkdose (IV, IM)
10mg/ml
de 1mkday(PO)
Tab: 250mg,
500mg
Susp:
Metronidazol 125mg/5ml
30-50mkday TID
e Inj: 500mg
Infusion:
500mg/100ml
Vial: 5mg/ml
Nafcillin 50-100mkday TID
Nalbuphine 0.1-0.2mkdose 10mg/ml
Tab: 5mg,
0.25mkdose (IV, IM)
Nifedipine 10mg, 20mg,
1mkday (OP)
30mg, 60mg
400,000U/day NB
Nystatin Oint: 5g
1.2M U/day
Tab:200mg,
Ofloxacin 20-30mkday 400mg IV Soln:
200mg/100ml
Tab: 500mg
Susp:
120mg/5ml,
Paracetamol 5-25mkdose q4h
250mg/5ml
Drops:
100mg/ml
50-100,00U/mkday,
Penicillin G 200,000-
1.2M U
(Penadur) 400,000U/mkday
(meningitic dose)
Tab: 15mg,
Phenobarbita 10mkdose (LD)
30mg, 60mg,
l 5nkdose (MD)
90mg
Amp: 130mg/ml
Phenoxymethy Adult: 250-500mg
lpenicillin QID
K Child: 50mkd QID
Piperacillin Vial: 2.25,
100-300mkday
(Tazocin) 4.5g
Prednisone
Tab: 5mg,
(Oracort,
1-2mkday 10mg, 20mg
Orasone,
Susp: 10mg/5ml
Prolix)
Tab: 500mg
Susp:
Pyrazinamide 15-30mkday
500mg/5ml,
250mg/5ml
Tab: 150mg,
1-2mkdose BID q8- 300mg
Ranitidine
12h Amp: 25mg/ml;
50mg/2ml
Cap: 300mg;
10-15mkday 450mg; 600mg
Rifampicin
(premeal) Susp:
200mg/5ml
Tab: 2mg
Syr: 2mg/5ml
Salbutamol
MDI:
(Ventolin,
0.15mkdose TID-QID 100mcg/dose
Asmalin,
Nebule:
Combivent)
2.5mg/5ml,
5mg/ml
Tab: 25mg,
Spironolacto
1-3mkday 50mg,
ne
100mg
Streptomycin 20-40mkday Vial: 1g
Sucralfate
1g/dose QID
(Iselpin) Tab: 1g
Terbutalin Tab: 2.5mg,
(Bricanyl, 5mg
0.075mkdose BID-TID
Terbulin, Syr: 1.5mg/5ml
pulmoxcel) Neb: 5mg/2ml
Tetracycline 20-50mkday QID Cap: 250mg
Tab: 125mg
Theopylline 20mkday q6h SR tab: 250mg
Syr: 80mg/15
DOPAMINE
Wt x ug/min ÷26.6
Ex: 40kg x 15ug/min or 10ug/min ÷ 26
DOBUTAMINE
Wt x ug/min ÷ 16.6
DOPAMINE DRIP
(5-8mg/k/min)
100cc 6 x wt x dose = 21mg of Dopamine
Rate___
1.6
79cc D5W + 21mg of Dopamine
HEMODIALYSIS PRESCRIPTION
KAWASAKI DISEASE
Febrile, examthematous, multisystem vasculitis
Fever for at least 4 days
+ clinical features (at least 4/5)
1. Bilateral bulbar conjuctival injection w/o
exudates w/ lumbar sparing
2. Erythematous mouth & pharynx, strawberry
tongue and red, cracked lips
3. Polymorphous, generalized erythematous
rash (morbilliform, maculopaular or
scarlatiniform )
4. Changes in peripheral extremities
(induration of hands and feet w/
erythematous palm & soles later
w/periungual desquamation)
5. Acute, nonsuppurative, unilateral cervical
lymphadenopathy at least 1.5cm in diameter
or if w/ coronary actery aneurysims
Treatment
IVIg high dose within 10 days
Aspirin
IVIg: 2g/kg as single dose over 10-12hrs
Aspirin: 80-100mg/kg/day x 4 doses
After fever is controlled, ↓ Aspirin to 3-5
mg/kg/day, discontinue after 6-8 weeks if
no heart problems
Improvemen No
O2 to Correct Improvement
t Acidosis
Hematocrit
Adjust IVT Hematocrit ↑↑
↓↓
DOPAMINE DRIP
200mg in D5W 200cc
mcgtt/mins = wt x DD/13.3
= wt x DD x 0.75
WEIGHT
6MOS-12MOS AGE in mos + 9 ÷ 2
1 YR-6YRS Yrs x 2 + 8
7YRS-12YRS Yrs x 7 - 5
HEIGHT
Ht in cm AGE in yrs x 5 + 80
Ht in inches AGE in yrs x 2 + 32
Light index
D2 diameter of collapsed lung
DH diameter of hemithorax on the collapsed side
% of pneumothorax= 100-(D23/DH3 x 100)
DOBUTAMINE DRIP
6 X WT in Kg = ______mg in 100ml
Nasal Cannula
5-6 40%
6-7 50%
7-8 60%
Sodium
The needed to infuse
DNa-Ana
0.5 meqs / hr
L
Amount of PNSS needed =
Computed Na deficiency ÷ 154
Drip rate = amount of PNSS needed
Time needed to infuse
Methylmed
30mkdose + 100cc D5W x 2h q 24H via
infusion pump x 3 doses
SCLEREMA NEONATORUM
- In an infant, fat has higher saturated-to-
unsaturated fatty acid ration compared to adult
fat and thus a higher melting point.
Prematurity, hypothermia, shock and metabolic
abnormalities have been postulated to further
increase this ratio, possibly as a result of
enzymatic alteration allowing precipitation of
fatty acid crystals within the lipocytes. This
condition has been suggested to result in the
dramatic clinical findings in affected skin. X-
ray diffraction techniques have confirmed that
infants with sclerema neonatorum have an
increase in saturated fats and that the crystals
within the fat cells are composed of
triglycerides.
Fluids and Electrolytes
Maintenance (24 H)
0-3 kg 75cc/kg
3-10 kg 100cc/kg
10-20kg 75cc/kg
20-30kg 60cc/kg
30-40kg 50cc/kg
>40kg 40cc/kg
Newborn
0-1 day 80cc/kg/hr
old
2 90cc/kg/hr
3 100cc/kg/hr
4 110cc/kg/hr
5 120cc/kg/hr
6 130cc/kg/hr
7 140cc/kg/hr
8 150cc/kg/hr
Mild Dehydration
30-50cc/kg/6h D50.3Nacl
Moderate Dehydration
60-90cc/kg/6h
¼ of computed deficit give D5LRX2hrs then ¾
to be given for the next 6hrs D50.6Nacl
Severe Dehydration
>100cc/kg/6h
1/3 with D5LRX2H then 2/3 with D50.3Nacl X
6H
Medical Prophylaxis
Diphtheria – update DPT immunization status
for all age
groups and Erythromycin 4-050mkd in 4
days divided doses X 10 days (max
2g/day).
Alternative: Benzathine Pen G IM single
dose
<30kg – 600,000 units
>30kg – 1.2 Million units
Hepatitis B
Newborn with HBsAg (+) mother
- HBIG 0.5mL and Hep B vaccine 0.5ml
IM at birth or w/in 12 hrs followed
by Hep B vaccine at 6 weeks after
and after 6 months.
Premature & HbsAg (-) mother
- Hep B vaccine delayed until child ≥
2000 gm
Sexual contact with HBsAg (+) partner,
exposure to blood/ body fluids
- Hep B vaccine + HBIG 0.06ml/kg IM
(not later than 14 days from
exposure from sexual contact and
with in 7 days for percutaneous
exposure)
Household/Sexual Contact with Chronic
Causes
- Hap B vaccine only
Malaria
Mefloquine (250mg/tab) to start 1 week
before travel then weekly until 4 weeks
after leaving endemic area as ff:
< 45kg = 5mg/kg (max: 250mg)
>45kg = 1 tab once a week
Doxycycline daily to start 2-3 days
before travel then daily until 4 weeks
after leaving endemic area
8 years old = 2mg/kg up to adult
dose of 100mg/day
Meningococcemia
Rifampicin in 2 divided doses X 2days
≤ 1 month – 5mkdose every 12 hrs
≥ 1 month – 10mkdose every 12 hrs (max
600mg)
Alternative: Ceftriaxone single IM dose
< 15 years old – 125mg
≥ 15 years old – 250mg or
Rheumatic Fever
Benzathine Penicillin 1.2 Million U IM
every 4 weeks
- <27kg (60lbs)- 600,000 U IM or
- Penicillin V 250mg PO twice daily for
patients allergic to Penicillin:
Erythromycin 250mg PO BID
Duration:
RF, (-) carditis: 5 years since last
episode ao ARF or until 21 years old
whichever is longer
RF, (+) carditis w/o residual heart
disease (no valvular disease): 10
years or until 21 years old whichever
is longer
RF, (+) carditis, (+) residual heart
disease:
10 years since last episode or at
least until 40 years old whichever is
longer
VACCINATION
Absolute Contraindications
Severe anaphylactic/allergic reaction to
previous vaccine
Moderate – severe illness ± fever
Encephalopathy within 7 days of vaccine
(pertussis)
Immunodeficiency (Congenital – all live
vaccines ) or households contact (OPV)
Pregnancy (MMR, OPV/IPV )
Relative Contraindications
Immunosuppressive therapy (all live vaccines)
Egg allergy (MMR)
Seizure w/in 3 days of last dose (Pertussis)
Shock w/in 48 hrs of last dose (Pertussis)
Fever >40.5°C w/in 48hrs of last dose
(Pertussis)
Not Contraindications
Mild illness ± low grade fever
Current antibiotic therapy
Positive PPD
Prematurity
Nursery
Please admit to NICU under the service of
Dr. _____
TPR Q15minutes until stable
Breastfeeding
Labs: CBC, APC, BT, RH typing, NBS at 24h
old
Medications:
1. Terramycin ophthalmic ointment OU
2. Vit. K 1mg IM
3. Hep B vaccine 0.5mL IM
S/O:
Routine newborn care
Gastric lavage
Suction secretion PRN
Thermoregulate at 36.5-37.5°C
Daily cord care w/70% IPA
Watch out for tachypnea, tachycardia,
alar flaring, retractions
Refer PRN
IVF:
TFR x wt/24h/20% (if with
phototherapy)
TFR x wt/24h-fdg-Aminosteril (use
formula if w/ Aminosteril & fdg)
eg: wt: 3kg TFR: 80
80x3/24/20%= 20 or
80x3=240x0.2= 48, next
240/48= 288/24h= 12cc/hr
Preterm
Please admit
TPR q15 minutes until stable
NPO
D10W 250ccx7cc/hr
Labs:
CBC, APC @24HDL
Blood & RH typing
Na, K, Ca
BUN, Creatinine 24HDL
NBS
ABG, Blood C/S, CBG q6H
CXR, APL
Vit. K 1mg IM now
Hep B 0.5 ml Im now
Terramycin/Erythromycin ophthalmic
ointment
Ampicillin – q12h
Oxygen
Attach to pulse oximeter
Seizure Disorder
Please admit
TPR q4h and record
NPO temporarily
Labs: CBS, APC, Urinalysis, fecalysis,
CBG now then q6h while on NPO
IVF: D50.3Nacl 500cc+2meq KCL/150ccIVF
post voiding
Meds:
S/O:
MIO qshift & record
Monitor VS q4h & NVS qhour &
record
Seizure precaution at bedside
Standby O2, padded tongue
depressor at bedside
Replace GI loses volume/volume
w/ PLR as sidedrip
Refer PRN
Dopamine
0.5-4µgm/kg/min – renal vasodilation
>10µgm/kg/min – vasodilation & decreased
peripheral and renal perfusion
5-10 µgm/kg/min – increase inotropic
effect and cardiac output = increase BP