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    Chest DZ: Multiple Choice Questions

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    IM CT
    This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

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    Chest DZ: Multiple Choice Questions

    Uploaded by

    IM CT
    12 views3 pages
    This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

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    Chest Dz

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    This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    12 views3 pages

    Chest DZ: Multiple Choice Questions

    Uploaded by

    IM CT
    This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    of 3

    Chest Dz

    Multiple Choice Questions


    Question 1. Recurrent or severe bacterial pneumonia does NOT usually complicate which one
    of the following conditions:
    A Complement C3 deficiency.
    B Primary antibody deficiencies
    C Secondary immunodeficiency.
    D Splenectomy.
    E Immunosuppression following renal transplantation.
    Question 2. Which one of the following statements about bronchial eosinophilia due to
    Aspergillus fumigatus is true?
    A Patients usually have chronic asthma.
    B The fungus is nearly always seen on chest X-ray.
    C Serum IgE levels are usually low or normal.
    D Precipitating antibodies to Aspergillus fumigatus are rarely found.
    E Eosinophils are never found in mucus plugs.
    Question 3. The presence of which one of the following cell types defines a granuloma on
    routine histology:
    A T lymphocytes
    B Basophils
    C Erythrocytes
    D Epithelioid cells
    E Giant cells
    Question 4. Which one of the following statements about idiopathic fibrosing alveolitis
    (cryptogenic fibrosing alveolitis) is true?
    A Patients are usually young.
    B Antineutrophil cytoplasmic antibodies are positive in 90% of patients at presentation.
    C A chest X-ray can show a ‘ground-glass’ appearance.
    D 50% of patients die within 6 months of diagnosis.
    E Lung transplantation is never effective in such patients.
    Question 5. Sarcoidosis is characteristically associated with a positive Mantoux test.
    A True
    B False

    Question 6. Extrinsic allergic alveolitis [EAA] is characteristically caused by


    exposure to an organic dust.
    A True
    B False
    Question 7. Kawasaki's disease often causes aortic aneurysms:
    A True
    B False
    Question 8. Hypercalcaemia in sarcoidosis, due to abnormal vitamin D metabolism, is a
    common feature.
    A True
    B False
    Question 9. The Churg-Strauss syndrome is associated with peripheral blood eosinophilia.
    A True
    B False
    Question 10. A first line treatment in granulomatosis with polyangiitis (formerly Wegener's
    granulomatosis) is cyclophosphamide and corticosteroids.
    A True
    B False
    Question 11. Which one of the following statements about Th responses is FALSE?
    A Th2 cells produce cytokines that favour the production of IgE
    B Th1 cells can be found in atopic eczema lesions.
    C Th2 cells characteristically express the Foxp3 gene product
    D Th2 cells produce IL-4.
    E Th1 cells are associated with the transcription factor T-bet.
    Question 12. Mast cells are not found in which one of the following sites?
    A Dermis
    B Gastrointestinal mucosa
    C Epidermis
    D Muscles
    E Respiratory mucosa
    Question 13. Which one of the following statements about skin prick testing is FALSE?
    A A useful diagnostic test for respiratory allergy
    B Is good for food allergy
    C Can cause an anaphylactic reaction
    D Is more reliable than specific IgE tests for hypersensitivity to an allergen
    E Detects type I hypersensitivity reactions

    Question 14. Which one of the following statements is NOT thought to be involved in asthma?

    A Activation of Th1cells
    B Epithelial cell activation occurs
    C Upregulation of VCAM-1 results in infiltration of eosinophils
    D Adrenaline is always used to reverse bronchoconstriction in mild asthmatics
    E Blocking activation of mast cells with a monoclonal antibody to IgE can give clinical benefit

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