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    Multiple Choice Questions: C Minimal-Change Nephropathy

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    This document contains 12 multiple choice questions about glomerulonephritis and kidney diseases. The questions cover topics such as the characteristics and causes of different types of glomerulonephritis, associations between diseases and histological findings, recurrence of glomerulonephritis after transplantation, and features of conditions like minimal-change nephropathy and myeloma kidney.

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    Multiple Choice Questions: C Minimal-Change Nephropathy

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    IM CT
    2K views3 pages
    This document contains 12 multiple choice questions about glomerulonephritis and kidney diseases. The questions cover topics such as the characteristics and causes of different types of glomerulonephritis, associations between diseases and histological findings, recurrence of glomerulonephritis after transplantation, and features of conditions like minimal-change nephropathy and myeloma kidney.

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    Renal Dz MCQs

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    This document contains 12 multiple choice questions about glomerulonephritis and kidney diseases. The questions cover topics such as the characteristics and causes of different types of glomerulonephritis, associations between diseases and histological findings, recurrence of glomerulonephritis after transplantation, and features of conditions like minimal-change nephropathy and myeloma kidney.

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    © All Rights Reserved
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    2K views3 pages

    Multiple Choice Questions: C Minimal-Change Nephropathy

    Uploaded by

    IM CT
    This document contains 12 multiple choice questions about glomerulonephritis and kidney diseases. The questions cover topics such as the characteristics and causes of different types of glomerulonephritis, associations between diseases and histological findings, recurrence of glomerulonephritis after transplantation, and features of conditions like minimal-change nephropathy and myeloma kidney.

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    © All Rights Reserved
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    of 3

    Multiple Choice Questions

    Question 1. In which one of the following types of glomerulonephritis is the serum C3 level
    characteristically normal?

    A Early acute post-streptococcal nephritis.


    B Active systemic lupus erythematosus nephritis.
    C Minimal-change nephropathy.
    D Membranoproliferative glomerulonephritis type II.

    Question 2. Which one of the following is the commonest cause of the nephrotic syndrome in
    children?

    A Henoch-Schönlein nephritis
    B Minimal-change nephropathy
    C Membranoproliferative glomerulonephritis
    D Acute post streptococcal glomerulonephritis
    E IgA nephropathy

    Question 3. Which one of the following conditions does NOT typically lead to rapidly
    progressive glomerulonephritis (RPGN)?

    A Goodpasture's syndrome.
    B Membranous glomerulonephritis.
    C Nephritis of Granulomatosis with polyangiitis (formerly Wegener's granulomatosis)
    D SLE

    Question 4. Direct immunofluorescent examination of a renal biopsy shows linear deposition of


    IgG along the glomerular basement membrane. Which one of the following is the most likely
    diagnosis?

    A Minimal-change nephropathy
    B Membranous nephropathy
    C Membranoproliferative glomerulonephritis
    D Amyloid disease
    E Anti-GBM nephritis

    Question 5. In acute post-streptococcal glomerulonephritis, which one of the following


    statements is true?
    A It only occurs following upper respiratory tract infection.
    B It typically follows within 5 days of streptococcal infection.
    C The anti-DNAse B titre is a better indicator of streptococcal skin sepsis than the ASO titre.
    D It is consistently associated with a normal C3 level in the early phase.
    E The clinical course is usually one of complete recovery in only 10% of children.

    Question 6. Which one of the following statements about glomerulonephritis is FALSE:

    A Membranous nephropathy is linked to HLA-DR3 in Caucasians.


    B In Goodpasture's syndrome, pulmonary haemorrhage is more common in smokers.
    C IgA nephropathy is a cause of 10?20% of cases of end-stage renal failure.
    D Glomerulonephritis recurs clinically in all allografted kidneys.

    Question 7. Which one of the following statements about C3 NeF is FALSE?

    A C3 NeF is produced by the kidneys.


    B C3 NeF is an IgG class autoantibody.
    C C3 NeF is characteristic of membranoproliferative glomerulonephritis (type II).
    D C3 Nef is just a marker and is not directly pathogenic.
    E C3 NeF may be transferred across the placenta into the foetal circulation.

    Question 8. Following cadaveric renal transplantation, which one of the following conditions is


    most likely to be associated with recurrence of glomerulonephritis in the allograft?

    A Minimal-change nephropathy
    B Membranoproliferative glomerulonephritis type II
    C Henoch-Schönlein nephritis
    D Polycystic disease
    E Post-streptococcal glomerulonephritis

    Question 9. Antibodies to neutrophil cytoplasmic antigens are characteristically found in which


    one of the following pathologies?

    A Pauci-immune crescentic glomerulonephritis


    B Goodpasture's syndrome
    C Amyloidosis
    D IgA nephropathy

    Question 10. Which one of the following histological terms means an increase in the number of
    cells within the glomerular tuft?

    A Focal
    B Cresentic
    C Membranous
    D Segmental
    E Proliferative

    Question 11. Minimal-change nephropathy is associated with highly selective proteinuria:

    A True
    B False

    Question 12. The presence of monoclonal free light chains (Bence Jones protein) in the urine is
    diagnostic of myeloma kidney.

    A True
    B False

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