The comment period just ended for the recent Cannabis Species Inflorescence Proposed Draft Monograph from the USP. The newest proposed monograph tightened the range of THC and CBD to 90 - 110% of the labeled amount. This is in alignment with most drug products but could be a challenge with the inherent variability of plant material. Another change to the monograph is the addition of a second option for microbial limits. The second option has significantly tighter limits for at risk populations such as immunocompromised patients. Not sure if the intent is to label product for different patient populations. Curious to hear thoughts on how this would be implemented! https://lnkd.in/gfGE6F6p
Wendi Young’s Post
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Cannabis education online at its best…👏👏
Enrollment Open in Core Cannabis
higherlearninglv.co
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Did you know there are over 700 known cannabis strains, each with distinct cannabinoid profiles 🌱🧬 Cannabis is often divided into 3 species—sativa, indica, and hybrid. Some fit neatly into one of these strains, but most are crossbred hybrids. #australiangrown #medcan #australianowned #terpenes
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Discover the Superiority of 10-OH-HHC. This cannabionid is born from HHC, a naturally occurring cannabinoid found in the cannabis plant. This transformation is facilitated by enzymes within our bodies, predominantly in the liver, a process that underscores its inherent suitability for human consumption. This natural synthesis within our own biological systems hints at a fundamental compatibility, suggesting that 10-OH-HHC is not just another external supplement but rather a substance in tune with our internal ecosystem. #10OHHHC #HHC #Potent #Cannabionids
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The 25 Most Important Cannabinoids There are two categories of cannabinoids: Phytocannabinoids and endocannabinoids. Phytos are those produced by cannabis/marijuana/hemp, while endocannabinoids are made by the human body. This series covers both.
The 25 Most Important Cannabinoids
higherlearninglv.co
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TFW you realize that you’ve created a monster. What does not kill me makes me smarter #MensaMafia I’ve found a subpar toxicology textbook — subpar because it doesn’t specify context for facts when discussing history of cannabis. E.g. Fu Xi was a mythical Chinese emperor. Fu Xi of the Xia dynasty is like a combination of Noah and Gilgamesh. The text does not specify this … though it does seem to indicate that Fu Xi smoked weed. Am I right? Probably some thirsty Kush valley sativa sticks from Afghanistan? However, the text does cover many different oxidant classes, including the Brown Recluse necrotoxin, which is a bundle of destructive enzymes including: - hyalurinidase: helps prevent restoration of lipids and helps deteriorate lipid boundaries by metabolizing hyaluronic acid (at least one reason why I was using a lotion with hyaluronic acid) - sphyngomyelinase: initiates cell death by lysis and lipid teardown. This causes the toxin to spread to nearby cells. This mechanism is responsible for the delayed & gradual onset of necrosis.
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Understanding the stability of your cannabinoids standards is essential to generating accurate data. In this 30-day study, we evaluated the stability of 16 acidic and neutral cannabinoids in blended working standards that were prepared in different diluents and stored across a range of laboratory conditions: https://lnkd.in/enB9Udfq
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Can you pick the samples with low and high total cannabinoids? While the breeders eye (experience, overall evaluation & observations, ??, TheArt!) is supported by various yield and quantitative trait assays, analytical chemistry often brings surprises…and may have the biggest influence on selection decisions. The range of total cannabinoids in these flowers is 12.9%-27%. All displayed high trichome density and all were worthy of selection, for one reason or another. #australianmade #medicinalcannabis #medicinalplants #acannabis2024 #phenotyping
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CBGVA is synthesized similarly to CBGA but involves olivetolic acid and another compound from the plant called divarinolic acid. It serves as a precursor to cannabinoids like CBCVA, CBDVA, CBGV, and THCVA, which then transform in the plant into more compounds like CBGa does with CBC, CBD, CBG, and THC through oxidization, heat, or time. https://lnkd.in/gFWbsTWU
Nature's Powerful CBGVA Transforms to THCVa: Research Analysis
globalcannabinoidrc.com
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🌿 Breaking Down the Science: THC vs. THCA 🌿 In our latest experiment, we took to the vibrant streets of San Francisco with special guest Lil Wyte to conduct a blind taste test—a "Pepsi Challenge" for cannabis enthusiasts. Participants compared a traditional THC joint with a THCA joint to uncover what truly delivers the better experience. Why THCA? THCA (tetrahydrocannabinolic acid) is a non-psychoactive precursor to THC. Once heated, it converts into THC, offering similar effects. Our goal with this challenge was to explore the potential of THCA and demonstrate how it stacks up against THC. What we found might surprise you! This initiative aligns with our mission at HHEMP.CO to educate consumers and innovate in the hemp and cannabis space. 🔬 Let’s spark the conversation: Have you tried THCA products? What’s your take on how they compare to traditional THC? Watch the video to see the results and share your thoughts in the comments. Together, let’s continue to explore the science behind plant medicine. 🌱💡 #THCA #THC #PlantMedicine #CannabisInnovation #HempEducation #poweredbyHHEMPCO
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Unlocking the Secrets of Strains: Leaf Shape, Color, and Effects Discover the fascinating world of cannabis strains and learn about the correlation between leaf shape, color, and the effects they produce. Understand why the commonly used distinctions between sativa and indica may not be accurate. Find out how cannabinoids and terpenes influence the euphoric or couchlock effects, and how cannabis receptors in our bodies play a role. #CannabisStrains #LeafShape #LeafColor #Cannabinoids #Terpenes #SativaIndica #Euphoria #Couchlock #CannabisEffects #CannabisResearch
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CSO at Medicinal Genomics Corporation
5moCan they present any data on the health risks for TAC and TYM? I’m curious how the USP satisfies Kochs postulates with tests that never identify a pathogen from a beneficial microbe? Seems like they are picking numbers out of thin air? On the other hand one can measure a minimum infective dose of a specific species and prove pathogenicity of the isolated organism.