𝗧𝗢𝗗𝗔𝗬! Mammalian synthetic biology is tricky, often requiring complex cloning strategies that can be difficult without modern DNA synthesis techniques. The Gao Lab at Stanford have had to overcome these challenges in the development of the innovative Retained Endoplasmic Cleavable Secretion (𝗥𝗘𝗟𝗘𝗔𝗦𝗘) platform, which allows protein secretion systems to achieve the same tuning capabilities seen in gene circuits but focused solely on proteins. It’s a great example of what enzymatic DNA synthesis can enable researchers to do, and we’re excited to highlight it in our next webinar. 🗓️ Tuesday, Dec. 10, 12pm ET 🔗 Sign up to watch live, or to get the recording: https://lnkd.in/egZEGwWH #DNAsynthesis #longDNA #Ansamers #biotech #synbio #SyntheticDNA #DNAInnovation #complexDNA #customDNA #AnsamerAnswers
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Join us on June 18th at 6 PM CEST for the upcoming Coffee break with TRANSFAC devoted to the topic of pathway analysis and identification of master regulators. Event details and joining link https://lnkd.in/eUqsKqSU In this webinar Dr. Alexander Kel, the CEO and CSO of geneXplain GmbH, will introduce you the Upstream Analysis approach that combines robust TRANSFAC TF binding site search with the fine pathway database TRANSPATH for reconstructing the key pathways and finding master regulators in them. You will learn how to use easy online tools that will automatically analyze your gene list, build specific gene regulatory and signal transduction pathway, find master regulators, and produce nice network visualizations ready for your paper. The following main questions will be in the focus of this seminar: Master regulators controlling the activity of transcription factors Walking pathways: pathway rewiring Integrated transcriptomics and proteomics analysis of Myc-induced U2OS cells (data from PMID: 26538417) Visualization of signalling pathways and networks #bioinformatics #SystemsBiology #geneXplain #TRANSFAC #TRANSPATH #HumanPSD #geneXplain_platform #CoffeeBreakWithTRANSFAC #GeneRegulation #Transcription #TranscriptionRegulation #TranscriptionFactors #Genes #research #Biology #PromoterAnalysis #TFBS #TranscriptionFactor #DNA #BindingMotif #PWM #PositionalWeightMatrix #TranscriptionFactorBindingSite #freeseminar #QandA #seminar #webinar #freewebinar #PathwayAnalysis #Pathways #MasterRegulator #MasterRegulators #Network #Networks #Reactome #KEGG #BioCyc
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Stuck with Pathway Analysis? Tools not working? Or it’s just you? Let’s break & understand, Save the date & Join us for a free online coffee break with Alexander Kel from geneXplain & get it sorted. Yes, you read it right, it’s free. . . . #bioinformatics #genexplain #transfac #Pathway #biotechnology #Industry #Seminars #biology #Free #
Join us on June 18th at 6 PM CEST for the upcoming Coffee break with TRANSFAC devoted to the topic of pathway analysis and identification of master regulators. Event details and joining link https://lnkd.in/eUqsKqSU In this webinar Dr. Alexander Kel, the CEO and CSO of geneXplain GmbH, will introduce you the Upstream Analysis approach that combines robust TRANSFAC TF binding site search with the fine pathway database TRANSPATH for reconstructing the key pathways and finding master regulators in them. You will learn how to use easy online tools that will automatically analyze your gene list, build specific gene regulatory and signal transduction pathway, find master regulators, and produce nice network visualizations ready for your paper. The following main questions will be in the focus of this seminar: Master regulators controlling the activity of transcription factors Walking pathways: pathway rewiring Integrated transcriptomics and proteomics analysis of Myc-induced U2OS cells (data from PMID: 26538417) Visualization of signalling pathways and networks #bioinformatics #SystemsBiology #geneXplain #TRANSFAC #TRANSPATH #HumanPSD #geneXplain_platform #CoffeeBreakWithTRANSFAC #GeneRegulation #Transcription #TranscriptionRegulation #TranscriptionFactors #Genes #research #Biology #PromoterAnalysis #TFBS #TranscriptionFactor #DNA #BindingMotif #PWM #PositionalWeightMatrix #TranscriptionFactorBindingSite #freeseminar #QandA #seminar #webinar #freewebinar #PathwayAnalysis #Pathways #MasterRegulator #MasterRegulators #Network #Networks #Reactome #KEGG #BioCyc
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How to identify master regulators in signal transduction networks? What molecules might be responsible for gene up-regulation in your experiments? Just two steps could help to get the results, promoter analysis to identify TFBSs and then pathway analysis to compute master regulators.
Join us on June 18th at 6 PM CEST for the upcoming Coffee break with TRANSFAC devoted to the topic of pathway analysis and identification of master regulators. Event details and joining link https://lnkd.in/eUqsKqSU In this webinar Dr. Alexander Kel, the CEO and CSO of geneXplain GmbH, will introduce you the Upstream Analysis approach that combines robust TRANSFAC TF binding site search with the fine pathway database TRANSPATH for reconstructing the key pathways and finding master regulators in them. You will learn how to use easy online tools that will automatically analyze your gene list, build specific gene regulatory and signal transduction pathway, find master regulators, and produce nice network visualizations ready for your paper. The following main questions will be in the focus of this seminar: Master regulators controlling the activity of transcription factors Walking pathways: pathway rewiring Integrated transcriptomics and proteomics analysis of Myc-induced U2OS cells (data from PMID: 26538417) Visualization of signalling pathways and networks #bioinformatics #SystemsBiology #geneXplain #TRANSFAC #TRANSPATH #HumanPSD #geneXplain_platform #CoffeeBreakWithTRANSFAC #GeneRegulation #Transcription #TranscriptionRegulation #TranscriptionFactors #Genes #research #Biology #PromoterAnalysis #TFBS #TranscriptionFactor #DNA #BindingMotif #PWM #PositionalWeightMatrix #TranscriptionFactorBindingSite #freeseminar #QandA #seminar #webinar #freewebinar #PathwayAnalysis #Pathways #MasterRegulator #MasterRegulators #Network #Networks #Reactome #KEGG #BioCyc
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Tomorrow marks the final session of our NanoString Technologies, Inc. / Bruker GeoMx Data Analysis Masterclass series is tomorrow! Throughout this series, we've covered essential topics like QC, AOI and gene removal, and custom normalization. Now, it's time to tackle the big question: identifying regulated genes in your experiment! This isn’t your typical RNA-seq dataset, so understanding the unique statistical methods required is key. Let our in-house expert Jessica Noll guide you through the right approaches to achieve reliable insights. Last chance to register: https://lnkd.in/dqXrQjyy Missed any sessions? Catch up on recordings at https://lnkd.in/dnMVHZKr Let’s make the most of this final session. See you there! #SpatialTranscriptomics #GeoMx #DataAnalysis #NanoString #Masterclass #Rosalind #Transcriptomics #Bioinformatics
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💡 Enzymatic DNA synthesis is set to revolutionize #biotechnology by overcoming the limitations of traditional chemical methods. This innovative approach allows the creation of longer and higher-quality DNA strands, which are crucial for gene therapy, vaccine development, and synthetic biology. Companies are developing technologies that promise faster, more efficient, and environmentally friendly #DNAsynthesis, potentially driving the next wave of scientific breakthroughs. At Blikka Genomics, we are proud to be at the forefront of these advancements. Our TdT Synthesis Panel features six proprietary Terminal deoxynucleotidyl transferase (TdT) enzymes, developed as a powerful starting point for synthesis workflows. These enzymes are meant to be evolved to precisely fit specific needs, in collaboration with our Protein Engineering team. 🔗 Discover more here: https://lnkd.in/ei3vu5w2 #Genomics #EnzymaticSynthesis #Biotech #ProteinEngineering
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**National Dimples Day: Unveiling the Genetic Magic Behind Beautiful Smiles** 💡 At BMKGENE, a part in the field of biotechnology and gene sequencing, we are excited to join you in celebrating National Dimples Day on July 9th. 🌟 Dimples, those charming indentations that grace our smiles, have always held a special place in our hearts. But have you ever wondered about the genetic code that gives rise to this captivating feature? With the development of gene sequencing technology, we believe that we can unlock the mysteries hidden within our DNA and gain a deeper understanding of the genetic factors that contribute to the formation of dimples. 🧬Our research not only enhances our knowledge of human genetics but also paves the way for potential advancements in healthcare and personalized beauty. As we celebrate the beauty of dimples today, we are reminded of the incredible complexity and diversity of our genetic makeup. 💪 Let's come together on this special day to appreciate the unique charm that dimples bring and embrace the beauty that lies within each of us. At #BMKGENE, we are committed to exploring the genetic wonders that shape our lives and using this knowledge to create a brighter future. #NationalDimplesDay #GeneSequencing #Biotechnology #HumanGenetics
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**National Dimples Day: Unveiling the Genetic Magic Behind Beautiful Smiles** 💡 At BMKGENE, a part in the field of biotechnology and gene sequencing, we are excited to join you in celebrating National Dimples Day on July 9th. 🌟 Dimples, those charming indentations that grace our smiles, have always held a special place in our hearts. But have you ever wondered about the genetic code that gives rise to this captivating feature? With the development of gene sequencing technology, we believe that we can unlock the mysteries hidden within our DNA and gain a deeper understanding of the genetic factors that contribute to the formation of dimples. 🧬Our research not only enhances our knowledge of human genetics but also paves the way for potential advancements in healthcare and personalized beauty. As we celebrate the beauty of dimples today, we are reminded of the incredible complexity and diversity of our genetic makeup. 💪 Let's come together on this special day to appreciate the unique charm that dimples bring and embrace the beauty that lies within each of us. At #BMKGENE, we are committed to exploring the genetic wonders that shape our lives and using this knowledge to create a brighter future. #NationalDimplesDay #GeneSequencing #Biotechnology #HumanGenetics
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Calling bio #datascientists: sure, you know about #knowledgegraphs, but have you met our biomedical knowledge bases? Here’s a prelude to what you get with our #BiomedicalKBs ⏯️ Learn more about Python-based ‘omics #datamining, #targetvalidation and gene set enrichment with our on-demand webinar 👉 https://lnkd.in/gTwNXnTJ
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❓In search of the optimal #scRNA-seq technology? In this rapidly evolving field, comparative studies are crucial for guiding the choice of the optimal tool, especially when handling challenging samples like #FFPE. Careful selection is essential to achieve the best outcomes. 🆚 In our latest article, we unveil the benchmarking results of a direct comparison study on FFPE samples between our #randomprimer-based #VITA platform and one of the few available alternatives. We are thrilled to present its remarkable performance: ✔ Exceptional sensitivity and detection ✔ Enhanced coverage at the gene and genome level ✔ Unique capabilities in capturing non-coding RNAs ✔ Precise cell type annotation 🔎Access the full details here: https://lnkd.in/eAscEH2F #M20 #scRNAseq #FFPE #biotechnology #innovation #rnasequencing #transcriptome #transcriptomics
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Have you heard about the latest #CRISPR breakthrough? Scientists tackle off-target effects with the revolutionary new tool, CRISOT. This innovative computational framework uses RNA-DNA fingerprints & machine learning to predict and minimize CRISPR errors. Read more about how CRISOT is making gene editing safer and more precise in today's blog: https://lnkd.in/ezVvk7v4 #GeneEditing #Bioinformatics #Science #Innovation
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