Shanta Whitaker-Toney,PhD,MPH

Shanta Whitaker-Toney,PhD,MPH

Washington, District of Columbia, United States
3K followers 500+ connections

About

🚀 Eleven years ago, I took a bold leap, shifting from a laboratory based microbiology…

Articles by Shanta

  • How I stopped hating Valentine's Day.

    How I stopped hating Valentine's Day.

    I hated Valentine's Day until I was 30. I would feel sad watching co-workers have flowers delivered to work or seeing…

    4 Comments
  • The (wo) men in the [professional] arena

    The (wo) men in the [professional] arena

    "It is not the critic who counts; not the one who points out how the successful professional stumbles, or where the…

    2 Comments
  • Let your passion fuel your purpose

    Let your passion fuel your purpose

    Choosing to leave my comfortable, well-paying job in 2012 was not an easy step to make. I had it good for the first…

    5 Comments

Experience

  • Continuum Health Group Graphic

    Continuum Health Group

    Washington DC-Baltimore Area

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    Washington, District Of Columbia

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    McLean, VA

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    Columbia, Maryland

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    Baltimore, Maryland Area

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    Remote

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    New Haven, Connecticut

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    Raleigh-Durham, North Carolina Area

Education

Licenses & Certifications

Publications

  • Call to Action: Data Diversity and STEM Education

    Change: The Magazine of Higher Learning

    We face a critical moment. To meet projected labor demands in science and engineering, the workforce of the future must be educated today in increasing numbers. Indeed, science, technology, engineering, and mathematics (STEM) underpin the government’s ability to defend the nation and to assure the vitality of the economy. STEM jobs are the fastest growing occupational category and, by 2020, 65% of all jobs in the U.S. will require a post-secondary degree with STEM literacy skills (Carnevale…

    We face a critical moment. To meet projected labor demands in science and engineering, the workforce of the future must be educated today in increasing numbers. Indeed, science, technology, engineering, and mathematics (STEM) underpin the government’s ability to defend the nation and to assure the vitality of the economy. STEM jobs are the fastest growing occupational category and, by 2020, 65% of all jobs in the U.S. will require a post-secondary degree with STEM literacy skills (Carnevale, Smith, & Strohl, 2013). However, according to the U.S. Department of Education, less than 25 percent of college students pursuing bachelor’s degrees will be specializing in STEM fields (NationalCenter for Education Statistics, 2012). In addition, the currentSTEM workforce is predominantly male and White orAsian, even as women and racial and ethnic minority groups are projected to comprise greater percentages of the U.S. population in the coming decades (Pew Research, 2016). To meet the growing global demand for a STEM workforce, every segment of the U.S. population will need to be engaged
    in a successful STEM education. A first critical step will be for academia, government, and nongovernmental agencies to understand the challenges diverse students face in their quest
    to join the STEM workforce.

    See publication
  • Reorganizing Nigeria’s Vaccine Supply Chain Reduces Need For Additional Storage Facilities, But More Storage Is Required

    Health Affairs

    One of the major problems facing Nigeria’s vaccine supply chain is the lack of adequate vaccine storage facilities. Despite the introduction of solar-powered refrigerators and the use of new tools to monitor supply levels, this problem persists. Using data on vaccine supply for 2011–14 from Nigeria’s National Primary Health Care Development Agency, we created a simulation model to explore the effects of variance in supply and demand on storage capacity requirements. We focused on the segment of…

    One of the major problems facing Nigeria’s vaccine supply chain is the lack of adequate vaccine storage facilities. Despite the introduction of solar-powered refrigerators and the use of new tools to monitor supply levels, this problem persists. Using data on vaccine supply for 2011–14 from Nigeria’s National Primary Health Care Development Agency, we created a simulation model to explore the effects of variance in supply and demand on storage capacity requirements. We focused on the segment of the supply chain that moves vaccines inside Nigeria. Our findings suggest that 55 percent more vaccine storage capacity is needed than is currently available. We found that reorganizing the supply chain as proposed by the National Primary Health Care Development Agency could reduce that need to 30 percent more storage. Storage requirements varied by region of the country and vaccine type. The Nigerian government may want to consider the differences in storage requirements by region and vaccine type in its proposed reorganization efforts.

    Other authors
    See publication
  • The Association Between Educational Attainment and Diabetes among men in the United States

    Few studies have examined the relationship between education and diabetes among men in the United States and whether this relationship differs by race/ethnicity. This study examined whether racial disparities in diabetes existed by educational attainment in 336,746 non-Hispanic White, non-Hispanic Black, and Hispanic men 18 years of age and older in the United States. Logistic regression models were specified to examine the odds of reporting diabetes by educational attainment. Within…

    Few studies have examined the relationship between education and diabetes among men in the United States and whether this relationship differs by race/ethnicity. This study examined whether racial disparities in diabetes existed by educational attainment in 336,746 non-Hispanic White, non-Hispanic Black, and Hispanic men 18 years of age and older in the United States. Logistic regression models were specified to examine the odds of reporting diabetes by educational attainment. Within race/ethnicity, both White and Hispanic men who had less than a high school education (odds ratio [OR] = 1.42, 95% confidence interval [CI] = [1.19, 1.69], and OR = 1.64, 95% CI = [1.22, 2.21], respectively) had consistently higher odds of diabetes than men with a bachelor's degree or higher level of educational attainment. Educational attainment did not appear to be associated with reporting a diagnosis of diabetes in non-Hispanic Black men. Identifying why educational attainment is associated with diabetes outcomes in some racial/ethnic groups but not others is essential for diabetes treatment and management.

    Other authors
    See publication
  • Leishmania pifanoi proteoglycolipid complex P8 induces macrophage cytokine production through Toll-like receptor 4.

    Infection and Immunity

    The P8 proteoglycolipid complex (P8 PGLC) is a glyconjugate expressed by Leishmania mexicana complex parasites. We previously have shown that vaccination with P8 PGLC provides protection against cutaneous leishmaniasis in susceptible BALB/c mice. However, the biological importance of this complex remains unknown. Here we show that P8 PGLC localizes to the surface of Leishmania pifanoi amastigotes and that upon exposure to macrophages, P8 PGLC binds and induces inflammatory cytokine and…

    The P8 proteoglycolipid complex (P8 PGLC) is a glyconjugate expressed by Leishmania mexicana complex parasites. We previously have shown that vaccination with P8 PGLC provides protection against cutaneous leishmaniasis in susceptible BALB/c mice. However, the biological importance of this complex remains unknown. Here we show that P8 PGLC localizes to the surface of Leishmania pifanoi amastigotes and that upon exposure to macrophages, P8 PGLC binds and induces inflammatory cytokine and chemokine mRNAs such as tumor necrosis factor alpha and RANTES early after stimulation. Our studies indicate that cytokine and chemokine induction is dependent upon Toll-like receptor 4 (TLR4). Interestingly, key inflammatory cytokines and chemokines (such as interleukin-6 [IL-6], macrophage inflammatory protein 1beta, and beta interferon [IFN-beta]) that can be induced through TLR4 activation were not induced or only slightly upregulated by P8 PGLC. Activation by P8 PGLC does not occur in the presence of TLR4 alone and requires both CD14 and myeloid differentiation protein 2 for signaling; this requirement may be responsible for the limited TLR4 response. This is the first characterization of a TLR4 ligand for Leishmania. In vitro experiments indicate that L. pifanoi amastigotes induce lower levels of cytokines in macrophages in the absence of TLR4; however, notably higher IL-10/IFN-gamma ratios were found for TLR4-deficient mice than for BALB/c mice. Further, increased levels of parasites persist in BALB/c mice deficient in TLR4. Taken together, these results suggest that TLR4 recognition of Leishmania pifanoi amastigotes is important for the control of infection and that this is mediated, in part, through the P8 PGLC.

    Other authors
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Projects

  • White paper on the Cardiovascular Disease Risk Factors among Medicare Beneficiaries: Review of Disparities and Opportunities

    Diabetes, smoking, obesity, and hypertension are cardiovascular disease (CVD) risk factors that significantly add to Medicare expenditures. The disparities associated with the aforementioned CVD risk factors and the current initiatives designed to improve CVD health outcomes for Medicare beneficiaries.

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  • The Business Case for Reducing the Most Prevalent Medicare Chronic Conditions

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    Presented data describing the economic burden of chronic disease disparities within Medicare.
    Special populations discussed: rural vs. urban, racial/ethnic minorities, dual eligibles, and males.
    Chronic conditions analyzed: mood disorders, congestive heart failure, and diabetes.

    Other creators
    • Alex Shangraw
  • National Alliance on Mental Illness (NAMI) Metropolitan Baltimore

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    NAMI is the nation’s largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness.
    I worked as a community consultant for the Metropolitan Baltimore branch to help revitalize its advocacy program. In addition, I assisted with the Smarts for Advocacy Training in mid January.

    See project

Honors & Awards

  • 2017 40 under 40 awardee

    Leadership Center for Excellence

    The Leadership Center for Excellence recognizes 40 emerging leaders under the age of 40 who demonstrate impact personally and/or professionally through their exceptional leadership in the DC metropolitan region. 40 Under 40 is an opportunity to show support for and invest in this next generation of trailblazers.

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