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It helps in the detection of Spinocerebellar Ataxia (SCA). It is a progressive, degenerative genetic disease with different types. There is a CAG trinucleotide repetition in chromosome 12q that gets affected resulting in the production of abnormal Ataxin 2 protein.
Software composition analysis (SCA) is an automated process that identifies the open source software in a codebase. This analysis is performed to evaluate security, license compliance, and code quality.
What to expect during the Spinocerebellar Ataxia Panel? A healthcare professional will collect blood sample. The sample will be sent to a laboratory where PCR fragment analysis will be performed to detect genetic mutations associated with spinocerebellar ataxias. The test report will be available on the 7th day.
Patient DNA is analyzed to determine the number of CAG trinucleotide repeats located within each allele of the five causative genes; an abnormally large number of CAG repeats is diagnostic for the disease. Two categories of tests are available: Spinocerebellar Ataxia Panel includes testing for all five types of SCA.
Diagnosing SCA Neuroimaging, using computed tomography (CT) and magnetic resonance imaging (MRI), can show atrophy of the cerebellum and other brain structures. Other forms of imaging can show changes in brain function. A definitive diagnosis of SCA can only be made with a genetic test.
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This test assesses for CAG repeat expansions within the ATXN1, ATXN2, ATXN3, CACNA1A, and ATXN7 genes, associated with spinocerebellar ataxia (SCA) type 1, SCA2, SCA3, SCA6, and SCA7. Additionally, testing for ATXN1 assesses for CAT trinucleotides that interrupt the CAG repeat tract.
A compliance-based assessment to determine if a systems security and privacy controls are implemented correctly.

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