Orchitis (Eng)

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EPIDIDYMITIS AND

ORCHITIS
Anita Suhadi, dr.
Definition

Epididymitis and orchitis are inflammation of the epididymis


and testes, respectively, with or without infection

American Family Physician, 2009


Epidemiology

2002 1 in 144 outpation visits (0.69 percent)

In men 18 to 50 years of age

Epididymitis is more common than orchitis

Isolated orchitis is rare and is generally associated with

MUMPS infection in prepubertal boys (13 years or younger)

American Family Physician, 2009


Risk Factor
Sexual activity

Bicycle or motorcycle riding

Prolonged periods of sitting

Urinary tract surgery

Instrumentation (patient with prostatic obstruction)

Anatomic abnormalities (meatal stenosis, posterior


urethral valves)

American Family Physician, 2009


Etiology and Pathophysiology

In men 14 to 35 y.o.a most commonly caused by sexually

transmitted Neisseria gonorrhoeae, or Chlamydia


trachomatis infection

Younger than 14 y, or Older than 35 y, generally caused

by infection with common urinary tract pathogens, such


as E. coli.

Mycobacterium tuberculosis, fungal and viral etiologies

can occurred in HIV patients


UK national guideline for the management
of epididymo-orchitis, 2010
Mumps give rise to inflammation of the testis which

causes sperm antigens to be released into the blood


circulation, resulting the anti-sperm antibodies in
circulation

Certain medication Amiodarone


Sign
Tenderness to palpation on the affected side

Palpable swelling of the epididymis

There may also be:

Urethral discharge

Secondary hydrocoele

Erythema and/or oedema of the scrotum on the affected side

Pyrexia

Prehn sign, the relief of pain with the elevation of the testis

Normal cremasteric reflex


Differential Diagnosis

American Family Physician, 2009


Diagnostic Testing
Gram stain and culture of swabbed urethral discharge

(recommended to detect urethritis and gonococcal


infection)

Urinalysis and urine culture

PCR assays for C. trachomatis and N. gonorrhoeae

Color Doppler ultrasonography (to rule out testicular

torsion by documenting blood flow)


Management
General Advice

Appropriate rest

Abstain from sexual intercourse until completed treatment and

follow up

Patient should given a detailed explanation of their condition with

particular emphasis on the long term implication for the health of


themselves and their partner.

UK national guideline for the management


of epididymo-orchitis, 2010
Treatment
For epididymo-orchitis most probably due to any sexually
transmitted pathogen:

Ceftriaxone 500mg IM single dose, plus


Doxycycline 100mg by mouth twice daily for 10-14days

If most probably due to Clamydia or other non-gonococcal


organism (no intracelullar diplococci)

Doxycycline 100mg by mouth twice daily for 10-14 days


or
Ofloxacin 200mg by mouth twice daily for 14days
UK national guideline for the management
of epididymo-orchitis, 2010
For epididymo-orchitis most probably due to enteric
organisms:
Ofloxacin 200mg by mouth twice daily for 14 days or

Ciprofloxacin 500mg by mouth twice daily for 10 days

UK national guideline for the management


of epididymo-orchitis, 2010
Complication
Reactive hydrocoele

Abscess formation and infarction of the testicle (rare)

Infertility in bilateral orchitis (13%)

An ongoing (chronic) inflammation

Managing epididymo-orchitis in general


practice, Walker 2013
Prognosis
With treatment, pain typically improves within 1-3 days

Take 2-4 weeks for induration to fully resolve

Prepubescent boys with epididymitis need a urology

referral because of the high incidence of urogenital


abnormalities

British Association for Sexual Health and


HIV, 2011)
Thankyou

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