Proposal New - 060952
Proposal New - 060952
Proposal New - 060952
ON
BY
MAY, 2023
OUTLINE
Chapter One
INTRODUCTION
Through reconstruction and image processing, the imaging technique known as computed
tomography (CT) creates three-dimensional (3-D) images of the interior of the body from x-rays
and a variety of detectors. Computed tomography (CT) has grown in importance as a medical
imaging technology since its inception in the 1970s as a complement to x-rays and medical
ultrasonography. It is now more frequently utilized for illness screening or preventive medicine.
Over the past 20 years, CT usage has substantially expanded in several nations 1. In the United
States, there were reportedly 72 million scans conducted in 2007 2. Cross-sectional imaging
examinations have been used much more frequently over the past two decades, and this rapid
uptake, along with ongoing advancements in their spatial and contrast resolution, have resulted
in a noticeable rise in the number of findings discovered that are unrelated to the examination's
main goals3,4,5.
Furthermore, the development of helical CT has led to numerous significant improvements in the
identification and characterisation of illnesses across the body. The most cutting-edge technology
for evaluating the abdomen is typically regarded as being helical CT 6. It can scan quickly and
acquire scans only when contrast enhancement is at its highest level, allowing for faster scanning
According to estimates, 0.4% of cancer cases in the US now can be attributed to CT scans from
the past, and with the rate of CT usage in 2007, this number could rise to 1.5–2% 8. It is
debatable if CT abdomino-pelvis is worth the expense and risk. Consequently, it is necessary to
Although the use of CT scans as the first line of diagnosis for abdomino-pelvic abnormalities has
scans is lower than that of CT and magnetic resonance imaging (MRI), and they reveal less detail
and fewer structures. The most frequent uses of CT are for tumor staging and the examination of
unanticipated findings that cannot be seen using x-rays or ultrasonic scans. It acts as a
confirming modality for pelvic and abdominal lesions. Although MRI images are more detailed
than CT images, CT is still the modality of choice for patients with metallic devices or implanted
electric devices like pacemakers that may be attracted to the MRI's strong magnetic field.
CT of the abdomen and pelvis is commonly done for a number of symptoms. The liver, kidneys,
pancreas, intestines, spleen, and pelvic organs such as the uterus, bladder, prostate, and rectum
are among the requests that are related to neoplasmic formation, suspected infections,
inflammatory disease, and certain requests that are related to the organs of the abdomino-pelvic
cavity. Even though there are significant commonalities between the various tissues' CT
appearances and clinical presentations, the findings are typically distinctive enough to point to a
particular diagnosis9. Without calming the structures and the surrounding tissues, it can be
This study will provide in-depth analyses of the CT abdomino-pelvic pattern findings and
compare those findings to the distribution of ages and sexes. It will clarify the primary
• To the best of the researcher's knowledge, there is lack of documented research findings
• Following the above problem, documentation and analysis of the age and sex distributions of
• To find out the age and sex distributions of adults referred for CT abdomino-pelvic and
•This work will help to determine the types of suspected leisions that are commonly referred for
CT abdomino-pelvis.
•This research will help to relate the occurrence of certain lesions to age and sex of the patients
•The research result will help in decision making and management of patients with certain
abdomino-pelvic lesions.
•This work would be retrospectively carried out on all the patients that had CT abdomino-pelvis
LITERATURE REVIEW
The bottom portion of the trunk, or abdomen, is located below the diaphragm. A bigger upper
portion, the abdomen proper, and a smaller lower portion, the true or lesser pelvis, are separated
by the plane of the pelvic inlet. The muscles that surround the abdomen in significant part are
easily adaptable to cyclical changes in the size of the abdominal cavity. They can become thinner
to accommodate abdominal distensions brought on by flatus, fat, a fetus, and fluid. The majority
of the gastrointestinal and urogenital systems are located in the belly. It also includes the
suprarenal glands, the spleen, and a large number of lymph nodes, blood arteries, and nerves.
Skin, superficial fascia, muscles, layers of fascia like the diaphragmatic fascia, fascia
transversalis, fascia iliaca, pelvic fascia, extra-peritoneal connective tissue, and the peritoneum
all provide a slick surface for the movements of the abdominal viscera against one another 10. The
abdominal cavity is substantially larger than what the anterior abdominal wall inspection would
have you believe. Since the domes of the diaphragm arch far over the costal margin, a large
portion of it is hidden by the lower ribs. The upper poles of the kidneys, both suprarenals, much
of the stomach, the liver, and spleen are all concealed by the lower ribs. There is a sizable
amount of abdominal cavity that extends into the pelvis in the back. just behind the buttocks 11.
Along with housing the rectum, uterus, prostate, and bladder, the pelvic cavity also has a sizable
portion of the intestine. The Latin word for pelvis is "basin," and when tilted forward into the
anatomical position, the bony pelvis does resemble a pudding bowl, although one with a large
portion of the front wall missing. The lower portion of the front abdominal wall fills in this
deficit11. The 'real pelvis' and the 'false pelvis' are separated by the pelvic brim. The Obturator
Intermus, Piriformis, Levator Ani, and Cocygeus are the pelvic muscles. The hip bones, which
are covered in the Obturator Intermus and its fascia, create the lateral wall of the pelvis. The
sacrum forms the curving posterior wall, and Piriformis enters the larger sciatic foramen
laterally.
The abdomen can be split into either four quadrants or nine regions to describe the placement of
perpendicular planes were to be drawn through the umbilicus and through the abdomen. The
umbilicus, which on most people is located at the level of the intervertebral disc between L4
and L5, is where one plane would be transverse through the abdomen. The umbilicus and the
symphysis pubis would be located in the vertical plane, which would also be the mid-sagittal
plane. The abdomino-pelvic cavity would be divided into four quadrants by the two planes:
NINE ABDOMINAL REGIONS can also be created by dividing the abdominal cavity into two
transverse and two vertical planes. The trans-tubercular plane and the trans-pyloric plane are the
two transverse planes. The lateral planes on the left and right are the two vertical planes. The
transtubercular plane is level with L5, while the transpyloric plane is level with the lower border
of L1. The mid-sagittal plane and each anterior superior iliac spine are where the right and left
lateral planes are situated; they are parallel to the mid-sagittal plane 12.
The nine areas that are thusly delineated are positioned in three zones: the median, the right, and
the left. The medium areas are the epigastric, umbilical, and hypogastric from above to below.
Hypochrondriac, lumbar, and iliac are the same regions on the right and left in the same
sequence.
Diagnostic x-rays are converted into a digital topographic image by computed tomography (CT).
In order to back-project an image using a mathematical technique, the basic idea of CT entails
digitizing an image obtained from a slit scan projection of the patient's body. Despite the fact that
CT scanning is often carried out transversely, sagittal and coronal sections can be created
digitally by processing the information. The image contains less scatter radiation because the CT
x-ray beam is constrained to a narrow slit13. An image of a much higher quality than what is
An image storage unit, computer, display console, couch, gantry, and x-ray tube are all
The mobile CT unit's frame is known as the gantry. The CT unit's most noticeable component, it
houses the x-ray tube and detectors. The gantry frame keeps the tube and detectors aligned and
houses the tools required to carry out the scanning motions. The gantry has a large aperture and
is used to position light sources like low-powered lasers and strong white halogen lights.
The first CT scanner was the original Electro-Musical Instrument Ltd (EMI) head scanner, which
intended solely for head inspection. It has a straightforward stationary tube and two sodium
transversely. After each transverse through 1800 with 10 rotations each scan, each linear
transverse provides 160 verticle values. The scan takes between 4.5 and 5 minutes.
projection fan-shaped beam rather than a pencil slit. It runs through 6 linear transverse scans,
THIRD GENERATION: To create a single projection, this uses a broader fan-shaped beam and
a curved array of 250–750 detectors. The linear scan and rotate system was eliminated because
the fan-shaped beam revolved 3600 times within the gantry and was wide enough to capture the
complete body in a single shot. The scan took between one and twelve seconds to complete13.
employs a single projection fan-shaped beam. The lack of movement caused by the detector ring
reduces the need for calibration. It is possible to scan for as little as 0.5 seconds or as long as 10
seconds. Helical/spinal CT units are one of the other contemporary CT unit designs.
technique. An electronic detector measures the strength of the emerging beam after an x-ray
beam passes through the patient. The x-ray tube and detectors are installed at the frame's
opposite ends, and the entire assembly was spun around the patient to collect measurements from
various angles.
The computer is supplied the received radiation measurement. Each area of the body's
attenuations is shown; bone often appears white and air as a black region. Due to the thinness of
the slices, it seems like a cross-section across the patient; there are no organs that would overlap
and obscure the image detail. As a result, some tiny structures that would not be visible with
conventional modalities can be resolved by the CT scan. For later usage, the image is saved on
Before the patient is positioned supine on the table with the arms raised, all metallic objects
from the belly and pelvis area must be eliminated. To enable the radiographer to choose the
appropriate scan range for the procedure, a scanogram or scout is acquired. Routine pelvis CT
protocols frequently include scanning from the iliac crest to the symphysis pubis, also in 7 - to
10-mm slices, while an abdomen CT protocol typically includes scanning from the diaphragm to
the iliac crest in 7 to 10 mm slices. Thicker slices may then be used to scan any questionable
areas that were visible. Faster exposure times have enhanced CT picture quality by reducing
peristaltic motion artifacts. Volume scanning has also practically eliminated anatomic mis-
registration, which happened when the patient took a separate inspiration for each slice in
procedure. They inhale deeply for two or three breaths, and are then instructed to hold their
breath for the needed 20 to 30 seconds for the scan. A full abdominal and pelvis scan may need
two volume acquisitions—one for the abdomen and one for the pelvis—depending on the
scanner and the patient's health. Between the two exposures, the patient can be given a little rest
period to regain their breath. The protocol specifies the pitch needed for the scan; it is
determined by the exam sought and the clinical history. The table speed and slice thickness are
correlated with the pitch. To guarantee that the anatomy is best pictured, the choice of pitch is
crucial.
Fig ia:CT abdomen: axial image through upper liver and spleen14
Fig ib: Axial anatomy through upper liver and spleen (T10/T11 approx)14
In abdominal and pelvic CT, oral/or rectal contrast media are necessary to separate the
gastrointestinal system from nearby structures. Large and tiny bowel segments that are not
Before the exam, oral contrast materials must be consumed in a way that will allow them to be
dispersed throughout the CT tract. The patient typically takes three doses of oral contrast. 1) The
evening before the test. (2) An hour prior to the test, and (3) Right before the test. This pattern
occurs because the contrast administered the previous evening will be in the large bowel, the
contrast administered an hour prior will be in the small bowel, and the contrast administered just
If oral contrast has not reached the rectum, contrast media may be placed rectally. Barium sulfate
suspensions and non-ionic water soluble solutions are the two forms of positive contrast agents
used to calm the gastrointestinal tract. Each has been demonstrated efficient in particular
applications.
Many delicious sulfate suspensions designed specifically for CT abdomen are available. Barium
sulfate suspension must have a low concentration (1% to 3%) in order to be beneficial in
abdominal CT and avoid streak artifacts on the image. If imaging is delayed after ingestion of the
contrast, beam hardening (streak) artifact may also develop because a large amount of the water
Abdominal CT frequently needs non-ionic iodinated intravenous contrast media, like Pamiray,
especially for the examination of the liver and pancreas 16. In the abdomen, vessel opacification is
useful for separating vessels from masses, determining vessel pathology, and integrating.
Abdomen
Lymphoma,
metastatic lesions of the liver, pancreas, kidney, adrenals, GIT, and spleen are among the
Trauma
Pelvis
Trauma;
Different people/groups of people have conducted research to examine the precise pattern of
study attempted to ascertain the results of a multi-detector CT scan. 47 abnormal scans were seen
in 58 patients with probable abdominal TB. They came to the conclusion that liver involvement
was least common and ascites was the most prevalent sign in patients with abdominal TB.
Hepatocellular carcinoma accounts for 80% to 90% of all liver malignancies and most frequently
affects adults in their 50s and 60s, according to Pan et al 18 in their investigation to identify the
prevalent CT abnormalities secondary to liver tumors. Hepatocellular carcinoma is the fifth most
frequent cancer worldwide, and colon cancer patients have a significant likelihood of liver
metastases. The most frequent primary liver tumor is a carvernous hemangioma, which can occur
anywhere between 0.4% and 20% of the time in the general population, according to research by
Karhunen et al19. on benign hepatic tumors and tumour-like disorders in men. Research on the
treatment of advanced hepatocellular carcinoma in the era of targeted therapy was done by Yan
et al20. According to their research, hepatocellular carcinoma is the most prevalent primary
Pancreatic cancer is the fourth and fifth most frequent cancer in both men and women, according
ductal adenocarcinoma. The ratio of men to women is 20:1. The majority of patients are above
pancreatitis, there are roughly 17 new instances of acute pancreatitis per 10,000 people in the
United States each year. 20% of acute pancreatitis cases were severe, whereas the other 80%
were mild. According to Remer et al23. examination of the imaging of chronic pancreatitis, there
are between 1.6% and 23% cases of the condition per 100,000 people worldwide each year. In
the United States, chronic pancreatitis prompts more than 122,000 outpatient visits. Prostate
cancer is the most prevalent non-cutanous cancer in men, according to research by Theodorescu 24
on prostate cancer diagnosis and staging, incidence, and death. In men under 40, it was hardly
ever diagnosed. 10% of male cancer-related deaths were attributable to it. Radiation dosages
were compared to patient age and disease severity by Morgan et al 25. They believed that patients
with severe acute pancreatitis got abdomino-pelvic CTs and were exposed to higher radiation
Smith et al26. came to the conclusion that non-contrast CT had 97% sensitivity and 96%
specificity for detecting renal calculi in their investigation to evaluate the specificity and
sensitivity of CT in the diagnosis of renal calculi. In order to support the use of pelvic CT scan as
a standard staging image study, Alvarado et al 27 performed a retrospective analysis to assess the
prevalence of pelvic metastases as the initial site of metastases in patients with head and neck
original melanomas. 146 patients met the requirements for inclusion. The median age was 59.5
years, and 73% of people were men. Primary melanomas were found in 40% of cases of scalp,
32% of face, and 16% of sinus, mouth, and conjunctiva. Recurrence metastases developed after a
49-month interval, although none of the patients had pelvic metastases as the initial location of
recurrence. They expressed the opinion that individuals with head and neck primary melanoma
may not require a pelvic CT scan as part of a routine staging evaluation. Berg et al 28. used CT
scans of 59 individuals with pelvic injuries to test the sensitivity for identifying pelvic disease
and instability. 86% of all pelvic injuries were discovered during the abdominal and pelvic CT
scan. The sensitivity of the trauma CT scan for detecting pelvic instability was 93%. According
to the results, a high-quality CT scan should be able to sensitively detect both pelvic instability
the remaining 5% of tumors. The efficacy of abdominal ultrasound scans, CT scans, and MRIs
for the diagnosis of inferior vena cava (IVC) tumor thrombus in renal cell carcinoma was
investigated by Hong-feng et al30. 25 patients had IVC tumor thombus and renal cell carcinoma
25. They came to the conclusion that abdominal ultrasonography was less effective in diagnosing
IVC tumour thrombus in renal cell carcinoma than CT and MRI. The presence of regenerating
nodules in individuals with liver cirrhosis at CT during arterial portography was studied by Lim
et al31. Included were 28 patients with hepatocellular carcinoma. Cirrhosis was discovered in the
resected liver in 20 patients, chronic hepatitis in 4, and a normal liver in 4. They demonstrated
that at CT arterial portography, regeneration nodules in cirrhotic liver were seen as enhancing
nodules surrounded by narrow, lower attenuation septa. When a patient with an abdominal
gunshot wound was chosen for non-operative treatment (NOM), Velmahos et al 32 analyzed the
results of an abdominal CT scan. There were 100 individuals with abdominal gunshot wounds
(AGWs). Forty individuals had their management changed as a result of the CT findings. They
came to the conclusion that choosing AGWs patients for NOM using abdomen CT scanning was
a safe and effective procedure. The CT scan has a sensitivity and specificity of 90.5% and 96%,
respectively.
In their study to compare plain radiograph and CT scan, Gill et al 33. examined 25 patients who
had double vertical pelvic ring fractures and evaluated the pelvis using both plain radiograph and
CT scanning. They provided some CT scan suggestions and came to the conclusion that routine
CT screening was not necessary for all pelvic ring injuries due to the increased expense and
radiation exposure. In their study to assess the staging of renal cell carcinoma, Vikram et al 34.
estimated that 2%–3% of the visceral malignancies were renal cell carcinomas. Men had a 1.6
In a study on the effects of CT in patients with their first episode of suspected nephrolithiasis, Ha
et al35 found that men were more frequently affected than women and that the prevalence rose
with age until the age of 60. In order to determine if the pelvic component of a standard
pathology, Ackermann et al36. looked into this. individuals with multiple organ involvement,
such as those with cancer and tuberculosis, were eliminated from the 133 individuals who
underwent CT scans. They came to the conclusion that, with staging renal mass and calculi
excluded, it was not required to include the pelvis in the radiation field when scanning a certain
upper-abdominal pathology.
According to Rana et al37., Renal cell carcinoma (RCC) accounts for 80–85% of all primary
renal cancers in adults and is the seventh most prevalent type of cancer. According to Rumpett et
al38., 0.4% to 2.6% of all renal carcinomas are collecting duct carcinomas (CDC), also known as
Bellini duct carcinomas, which develop from the conducting duct epithelium of the kidney. The
patient was typically 53 years old. When patients with non-traumatic stomach complaints visit
the emergency room, Abujudeh et al 39 aimed to ascertain how CT affects doctors' diagnostic
confidence and treatment choices. 584 patients who had non-traumatic stomach complaints were
included in them. Fisher's exact test and the log likelihood ratio were used to evaluate changes.
The two most frequent diagnoses were renal colic and intestinal obstruction (119 out of 584, or
20.4% and 13.7%, respectively). In 49% of patients, CT altered the primary diagnosis. The main
conclusions were that CT scanning enhanced diagnostic confidence from 70% to 90% and
correlation and their findings allowed for the full delineation of the tumor's area as well as the
identification of local invasion and distant metastases. Hakan et al 41. conducted a study to
examine the computed tomography (CT) and magnetic resonance imaging (MRI) results of
gastrointestinal system lipomas. They came to the conclusion that a lipoma can be accurately
planning.
By retrospectively reviewing the abdominal CT scans of 28 patients who had undergone barium
examinations for this condition, Florian et al 42. characterized the CT findings of jejunal
diverticulosis and came to the conclusion that jejunal diverticula had characteristics findings on
CT, appearing as discrete round or avoid contrast collection or air-containing structure outside
with expected lumen of small bowel with smooth wall and no-recognizable small-bowel fold. In
this investigation, Kim et al43. used two pneumatosis cystoids coli patients to examine computed
tomography colonographic findings. Multiple gas-filled cysts were visible in the colon's wall on
a CT scan.
The accuracy of computed tomography (CT) in differentiating between the three patho-
physiological types of cecal volvulus was assessed by Eric et al 44. by analyzing the computed
tomography (CT) features of cecal volvulus. They included 10 patients who had cecal volvulus
that had been surgically verified. The findings demonstrated that CT was a good diagnostic tool
for identifying the three patho-physiological kinds of cecal volvulus in addition to diagnosing
In order to establish a standard for this CT research and to determine the efficacy of CT in the
diagnosis of abdominal wall hernias, Hoejer et al45. conducted a study. The examination of 24
patients with probable abdominal wall hernias. All underwent surgery. Two radiologists
evaluated the CT scans to determine the interobserver variation. The accuracy of the two
radiologists' CT diagnosis was 83% and 79%, respectively. Both CT examinations' sensitivity
and specificity were 0.83 and 0.67, respectively. Positive CT results had a 0.94 and 0.88
predictive value, while negative CT results had a 0.63 and 0.57 predictive value. The variation
between observers was 0.87. The study concludes that while a negative CT finding does not rule
out the diagnosis, a positive finding of an abdominal wall hernia is trustworthy. The CT
CT conducted before the occurrence of bowel obstruction (pre-CT) is helpful in predicting the
presence of post-surgical intestinal obstruction, Obuchi et al 46. explored this. The pre-CT results
of 33 patients with post-surgical intestinal blockages were examined. The pre-CT findings were
compared to the post-CT findings in 16 patients who had intestinal obstruction and to the
a disparity in the bowel's caliber, the existence of two adjacent collapsed loops, the appearance
of the gut as if it were beaked, focal distention and/or wall thickness of the loops, and twisted
mesentery. Of 33 patients, 23 (or 70%) exhibited one or more of these pre-CT abnormalities. On
both the pre- and post-CT, all patients with a surgically shown closed loop obstruction had two
contiguous collapsed loops. Conservative therapy was shown to be ineffective in six (86%) of
seven patients who had focal dilated bowel loops and twelve (71%) of seventeen individuals who
had twisted mesentery on pre-CT. Pre-CT revealed a number of important discoveries. In light of
the fact that these findings can indicate the presence of post-surgical bowel obstruction and that
two adjacent collapsed loops on pre-CT are a marker of the presence of post-surgical closed loop
obstruction, they came to the conclusion that attention should be paid to these findings.
Localized intra-hepatic bile duct dilatation without a visible tumor or stone as shown on CT
scans was studied by Poortman et al 47. to determine the parameters that can indicate the existence
of a malignancy. The study comprised a total of 29 patients (male: 16, female: 13) with localized
intrahepatic bile duct dilatation without a visible mass, stone, or damage as shown on CT
imaging. Review of tumor marker levels, CT scan results of the intra-hepatic bile duct, and
related findings, as well as a history of extra-hepatic malignancy and biliary stone disease, were
conducted. The results were divided into two groups (patients with a malignancy and patients
with a benign condition) for analysis at a later time. 11 patients out of 29 had malignant lesions
Retrospective analysis of the abdomen CT results of 120 patients, whose CTs were performed
under the clinical impression of pancreatic disorders, was done by Han et al 48. Included in this
group are 20 people with acute pancreatitis, 12 people with chronic pancreatitis, and 41 people
with pancreatic tumors. 47 people were still found to have healthy pancreas. 108 out of 120
patients had the proper diagnosis made thanks to CT, which had 91% diagnostic accuracy, 95%
sensitivity, and 79% specificity. Positive CT diagnoses had a 93% predictive value, while
negative diagnoses had an 82% predictive value. Diffuse pancreatic enlargement (75%),
obliteration of peripancreatic fat planes (70%), peripancreatic "Dirty fat" (50%), and renal fascial
thickening (50%), were the most often seen CT findings of acute pancreatitis. The consequences
of acute pancreatitis included fluid accumulation, phlegmon, abscess formation, and pseudocyst
formation.
To the best of the researcher's knowledge, only a small number of studies have been conducted
Additionally, the justifications for referring patients for CT abdomen/pelvis are not conclusively
in eastern Nigeria (ESUTH and POSH), relate the findings to the age and sex distribution of the
patients, and define the primary indications for referral for CT abdomino-pelvis, this work has
several objectives.
CHAPTER THREE
RESEARCH METHODOLOGY
This study will be done in two radiography department in Enugu state i.e. Enugu State
The study will be carried out in different hospitals within Enugu metropolis
Request cards and radiologist reports of patients available and within the selected
hospitals.
Request cards and radiologist reports of patients above the ages of 20 years.
Request cards and radiologist reports of patients outside the selected hospitals.
Request cards and radiologist reports of patients below the age of 20 years.
The sample size that will be used in the study will be based on the available data during the
Ethical approval will be gotten from the human research and ethics committee of the selected
hospitals. All data will be treated will discretion, and used only for the research purpose.
The data collected will be secondary data. It will be collected by the researchers from involved
facilities.
The instrument for data collection will be patient request cards and radiologist reports.
Information from the request cards and reports will be extracted and analyzed by the researchers.
The data will be analyzed using the Statistical Package for Social Sciences (SPSS) version 23.
Descriptive statistics like percentages and frequencies will be used in the analysis. Spearman’s
correlation will be applied to ascertain if any correlation exists between gender, and age and the
findings from the request cards and report. The results will be presented using tables and figures.
A p-value less than or equal to 0.05 will be used as a criterion for statistical significance.
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