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INTRODUCTION

• Vitamins are organic compounds that people need in


small quantities. Most vitamins need to

come from food because the body either does not


produce them or produces very little, A

vitamin is an organic compound, which means that it


contains carbon. It is also an essential

nutrient that the body may need to get from food.


CLASSIFICATION:
• One major difference between water-soluble and fat-soluble vitamins is the way they are

• absorbed in the body. Water-soluble vitamins are absorbed directly from the small intestine

• into the bloodstream. Fat-soluble vitamins are first incorporated into chylomicrons, along

• with fatty acids, and transported through the lymphatic system to the bloodstream and then

• on to the liver. The bioavailability (i.e., the amount that gets absorbed) of these vitamins is

• dependent on the food composition of the diet. Because fat-soluble vitamins are absorbed

• along with dietary fat, if a meal is very low in fat, the absorption of the fat-soluble vitamins

• in that meal may be impaired.
1-Water Soluble Vitamins
Thiamine (vitamin B1)
• S a water-soluble vitamin that acts as an essential cofactor for various
pathways of
carbohydrate metabolism. Thiamine also acts as a cofactor in the
metabolism of glyoxylic
acid. It is absorbed rapidly after oral, intramuscular, or intravenous
administration. However,
parenteral administration is recommended for initial management of
thiamine deficiency

syndromes.
Food sources
Mechanism of Action:
• Thiamine exerts it`s action by influencing carbohydrate metabolism.

• It combines with ATP to form thiamine pyrophosphate in the body.
Thiamine pyrophosphate

• acts as a coenzyme for carbohydrate metabolism, decarboxylation of
ketoacids, and hexose

• monophosphate shunt. It also has played some role in neuromuscular
transmission.
Function
• Carbohydrate metabolism and energy production, Vitamin B1 regulates the

• functioning of the nervous system, heart and brain, it is also prescribed to AIDS
patients to

• partly compensate for the loss of immunity caused by the disease, Vitamin B1 is
important to

• maintain mental health. It may also reduce the likelihood of memory
impairments and

• diseases like Alzheimer’s.
Vitamin B1 Deficiency Symptoms:

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