About Liver Function Test

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About Liver Function Test (LFT)

The Liver Function Test (LFT or Hepatic Function Test) is a blood test panel that includes
several tests that measure specific proteins and liver enzymes to get an overall sense of how
well the liver is working.

What is the Liver Function Test?

The Liver Function Test checks for the following:

 Alanine aminotransferase (ALT/SGPT) - ALT is an enzyme found


predominantly in the cells of the liver. When the liver is damaged, ALT is
released into the blood.
 Albumin - Albumin is a protein made by the liver. Measuring levels of
albumin is helpful in diagnosing liver disease. An albumin test measures how
well your liver is making the proteins that your body needs.
 Albumin/Globulin Ratio (calculated) - The A/G ratio is calculated from
measured total protein, measured albumin, and calculated globulin (total
protein - albumin) to help diagnose diseases.
 Alkaline phosphatase (ALP) - In conditions affecting the liver, damaged liver
cells release increased amounts of ALP into the blood.
 Aspartate aminotransferase (AST/SGOT) - AST is a liver enzyme that is
useful in helping to diagnose liver diseases.
 Bilirubin, Total - This test measure direct and indirect levels of bilirubin for a
total bilirubin value. In cases of an obstruction or inflamed liver, the liver
cannot eliminate excess bilirubin. When the body has too much bilirubin,
your skin and the whites of your eyes will start to yellow causing a condition
called jaundice.
 Bilirubin, Direct - Bilirubin is made in the body when old red blood cells are
broken down. Bilirubin attached to sugar is called “direct” or “conjugated”
bilirubin.
 Bilirubin, Indirect - Bilirubin that is not attached to sugar is called “indirect”
or “unconjugated” bilirubin.
 Globulin (calculated) - Globulin is a protein made in your liver and helps the
immune system fight infections. Low globulin levels can be a sign of liver
damage or other conditions.
 Total Protein - Total protein measurements can help diagnose liver
diseases. Total Protein measures the amount of protein in your blood. The
two main proteins found in the blood are globulins and albumin

 How is a Liver Function Test Administered?


 It is important to note that fasting is not required to take this test. A small
amount of blood will be drawn, and your blood will be tested for a
combination of different chemicals.

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