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    Tablet Machine

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    Anonymous yBhOAi5UH
    Tablet compression machines produce tablets by pressing granules between an upper and lower punch in a die. The basic principle is hydraulic pressure, which allows for multiplying force as needed. There are four stages to the compression process: filling the die cavity with granules, metering to control the granule weight, compression as the punches come together to form the tablet, and ejection where the tablet is removed from the die. Modern machines can produce over 500,000 tablets per hour and use automatic weight control for consistent results.

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    Tablet Machine

    Uploaded by

    Anonymous yBhOAi5UH
    418 views3 pages
    Tablet compression machines produce tablets by pressing granules between an upper and lower punch in a die. The basic principle is hydraulic pressure, which allows for multiplying force as needed. There are four stages to the compression process: filling the die cavity with granules, metering to control the granule weight, compression as the punches come together to form the tablet, and ejection where the tablet is removed from the die. Modern machines can produce over 500,000 tablets per hour and use automatic weight control for consistent results.

    Original Description:

    principle based

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    Tablet compression machines produce tablets by pressing granules between an upper and lower punch in a die. The basic principle is hydraulic pressure, which allows for multiplying force as needed. There are four stages to the compression process: filling the die cavity with granules, metering to control the granule weight, compression as the punches come together to form the tablet, and ejection where the tablet is removed from the die. Modern machines can produce over 500,000 tablets per hour and use automatic weight control for consistent results.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    418 views3 pages

    Tablet Machine

    Uploaded by

    Anonymous yBhOAi5UH
    Tablet compression machines produce tablets by pressing granules between an upper and lower punch in a die. The basic principle is hydraulic pressure, which allows for multiplying force as needed. There are four stages to the compression process: filling the die cavity with granules, metering to control the granule weight, compression as the punches come together to form the tablet, and ejection where the tablet is removed from the die. Modern machines can produce over 500,000 tablets per hour and use automatic weight control for consistent results.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Tablet compression machine makes the tablets by pressing the

    granules in die with lower and upper punch.


    Ankur Choudhary | Equipment | Production | PrintBe the first to comment!

    Tablets are being formed by compressing the granules using the


    compression
    machines.
    Different
    innovations
    to
    tablet
    compression machines are being done to improve the production
    rates and now it is possible to produce more than 500,000 tablets
    per hour. A tablet formation takes place by the combined pressing
    action of two punches and a die.

    Principle of Tablet Compression Machine:


    The basic principle behind the tablet compression machine is
    hydraulic pressure. This pressure is transmitted unreduced
    through the static fluid. Any externally applied pressure is
    transmitted via static fluid to all the directions in same proportion.
    It also makes it possible to multiply the force as needed.

    Different Stages of Compression Process:


    The tablet compression procedure that is used in different
    pharmaceutical companies is divided into four distinct stages.
    These are named as filling, metering, compression and ejection.

    These
    all
    four
    steps
    are
    explained
    below:
    1. Filling: This procedure of the tablet compression machine
    involves transfer of the granules into position for tablet
    compression. The ultimate product is then blended for
    homogeneous blend. Then the mixture flows to thecompressing
    tool punch-die cavity. The punch-die cavity is made of punch-die
    and lower punch. Then the position of lower punch in the die is
    responsible for the volume of the cavity. This volume must be

    appropriately adjusted for weight of granules to be compressed to


    make
    the
    tablets.
    2. Metering: The metering procedure for the tablet compression
    procedure involves removal of excess granules from the
    compression machine. At this stage the required weight (volume)
    of granules to be compressed into tablets is controlled by the
    height of the lower punch in the die and the height of the lower
    punch is controlled by the metering cam. The lower punch is
    raised to the required level in the die to get the required weight of
    granules in the punch-die cavity. The excess granules are scraped
    from the surface of the die table. The metering method is similar
    to the process used to determine the weight of flour during the
    making
    of
    a
    cake.
    3. Compression: During compression stage the top and bottom
    punches come together by pressure within the die to form the
    tablet. As the punches enter into the compression stage, the top
    and bottom punches move between two large wheels called
    compression rolls. These compression rolls push the punches to
    words the die to form the product. So, distance between the top
    and bottom punches determines the thickness and the hardness
    of the tablets. When the punches are so close together, a thin and
    hard tablet is created. Today AWC (auto weight control) machine
    is
    used
    for
    better
    result.
    4.
    Ejection: The
    ejection
    procedure
    for
    the tablet
    compression process involves removal of the tablet from the
    lower punch-die station. In this stage, the upper punch retracts
    from the die cavity and rises above the turret table. Then the
    lower punch rises in the die, which in turn pushes the tablet
    upward to the top surface of the die table and out of the die
    cavity. Then by a scrapper tablets are collected in the container.
    There are different types of compression machines are available
    for tablet manufacturing and these have their identification on the
    basis of the number of tablet compression stations as 25 station,
    35 stations, 55 stations etc.

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