Lile Wellness’ Post

As public health initiatives evolve, we need to begin to incorporate new initiatives such as genomic testing in order to move forward and make an impact for our aging population. Implementing genomics into public health can help lengthen patient health lifespans by being proactive instead of reactive. Nine out of the 10 leading causes of death and disease in the U.S. can be overridden with our genome. That’s why I’m advocating for pharmacists to be credentialed genomic consultants. It starts with education; We must embrace innovative strategies and integrate them into the medical curriculum. Universities need to take the lead by incorporating these innovative concepts into their curricula and establishing pilot programs to test and refine the new model. #PersonalizedMedicine #Genomics #PharmD #HealthcareInnovation #PatientCare #PracticeOfTheFuture #FutureOfMedicine 

I personally love nothing more than looking at genomic data and pondering over the nuances of interpretation....🤓 However, if the plan is "mainstream" pharmacogenomics and apply it into routine practice, most healthcare professionals (HCPs) spearheading this implementation will (quite appropriately) not have the time or inclination to obsess over results. It will not be geneticists or clinical pharmacologists delivering pharmacogenomics on a routine basis. So how do we ensure HCPs have the requisite level of knowledge to use pharmacogenomics as part of their daily practice? Plus, how do we do this without burdening already overstretched HCPs with yet another thing they need think about. There are many potential solutions, lots of which were excellently summarised by Jessica Keen in her talk at our British Pharmacological Society event last week. A dedicated information solution is key, but that's a separate post! One tool that can be accessed immediately is the Genomics Education Programme's GeNotes platform. This houses "just-in-time" resources which are designed to deliver clear and concise packages of information at the point of need. • In clinic and need to know more about CYP2C19 genotyping for Mavacamten? - You can find a dedicated resource on our "In the clinic" section. • Want to find out more about genetic testing to avoid hearing loss from aminoglycosides? - Take a look at our knowledge hub. With colleagues from around the country, we've developed over 30 resources and many more are in development. The site is free to access and constantly undergoing curation. Take a look and please get in touch if you have any thoughts or feedback about the system. https://lnkd.in/dAGaFF-J

Dear PGx advocates, I wanted to share an invaluable resource for all things PGx knowledge. Whether you're diving deeper into pharmacogenomics or looking to stay updated on the latest research, this resource has you covered. Check it out and let's continue advocating for personalized medicine together!

Implementation science is important to improving translation of evidence into practice. Read our newly released chapter in Cardiovascular Outcomes Research: A Clinician’s Guide to Cardiovascular Epidemiology and Clinical Outcomes Trials titled Implementation Science: Strategies to Improve Adoption and Adherence to Clinical Practice Guidelines. We explain step-by-step how to include implementation science into your practice. Mitchell Sarkies Michael Gionfriddo #MyCompany https://lnkd.in/e5PeQxvj

#Statistics #Bayesian In practising medicine, physicians often face uncertainty in diagnosis, prognosis, and therapy recommendations. Skilled physicians use probabilistic reasoning to navigate this uncertainty, progressively reducing it with accumulated information. Similarly, the Bayesian statistical framework views clinical research as a process of progressively reducing uncertainty about a hypothesis. While frequentist statistics, dominant in the 20th century, introduced concepts like p-values and confidence intervals, they often remain abstract and counterintuitive. Bayesian statistics, on the other hand, offers a more intuitive approach. It combines prior information with new data to update probabilities, providing a flexible and informative method for clinical research. Modern computing advancements have made Bayesian methods increasingly feasible in medical research. Bayesian analysis allows for a more nuanced understanding of clinical data, facilitating better design, analysis, and interpretation of clinical trials. This approach can sometimes yield markedly different conclusions from frequentist analysis, highlighting its potential to transform clinical research. Read the Review published in The Lancet. #BayesianStatistics #ClinicalResearch #MedicalResearch #DataAnalysis #Probability #FrequentistStatistics #Healthcare #UncertaintyReduction #StatisticalMethods #MedicalInnovation #ResearchDesign #HealthcareAnalytics #EvidenceBasedMedicine #ClinicalTrials #DecisionMaking

🌟 Call for Papers: Journal of Advanced Research in Medical and Health Science (ISSN: 2208-2425) 🌟 Are you working on groundbreaking research in medical and health sciences? The Journal of Advanced Research in Medical and Health Science (JARMHS) invites high-quality, original manuscripts for publication in upcoming issues. 📌 Key Areas of Interest: Clinical and experimental medicine Healthcare management and policy Epidemiology and public health Biomedical innovations Nursing and allied health sciences Cutting-edge medical technology 📌 Why Publish with Us? ✅ Global Reach: Open-access platform ensures your work reaches a worldwide audience. ✅ Rapid Review: Efficient peer-review process for timely publication. ✅ Indexed Journal: Enhance your academic visibility and citation impact. ✅ Experienced Editorial Board: Guidance from esteemed experts in the field. 💡 Submission Deadline: Ongoing 30 November 2024 💡 Article Processing Charge: Currently offering an exclusive 30% fee waiver for a limited time! 🔗 Submit Now: https://lnkd.in/gW3ZUSMt 📢 Let your research shape the future of healthcare! Join a community of leading researchers and practitioners advancing knowledge and innovation. 📩 For queries, feel free to contact us at [email protected] 🔬 Your research deserves to shine. Let us help you make it impactful. #MedicalResearch #HealthScience #CallForPapers #OpenAccess #MedicalJournals

The US leads the world in medical research and innovation. The US government is also the largest funder of medical research. Pragmatic US government leadership is even more critical at this juncture, when we are on the cusp of enormous progress in medical science driven by a combination of technologies. Most known diseases will be preventable or curable soon. Human life and health spans will see a huge boost in the coming decades. Jay Bhattacharya's appointment to lead NIH is an important move to grab the opportunity to help and accelerate the process. https://lnkd.in/g7ptuZ3j

Integrating Genomics into Clinical and Public Health Practices Research Forum: Need for Better Understanding among Health Care Practitioners.

BePRECISE Issues Guidelines for Accuracy and Equity in Precision Medicine The BePRECISE consortium has published guidelines aimed at improving the accuracy, safety, and health equity in precision medicine. These are all critical issues in the field that have been largely overlooked. The paper appears in Nature Medicine and the lead author is Siew S. Lim, of Health Systems and Equity at Monash University. https://hubs.li/Q02JTc_80

🍃Kratom and adverse events? Maybe. Yet the National Institute Of Health asks, are you sure it’s conclusive? When people report adverse reactions after taking kratom, it's easy to assume that kratom caused the problem. This assumption is based on the logical fallacy "post hoc ergo propter hoc," which means "after this, therefore because of this." Just because one event follows another doesn't mean the first event caused the second. In medical news, this kind of faulty reasoning can lead to false conclusions and mislead the public. The National Institutes of Health (NIH) emphasizes that it's crucial to be careful with such assumptions because they can lead to faulty medical conclusions. To avoid these errors, researchers and journalists need to carefully evaluate data and distinguish correlation from causation. The linked article from the NIH explains why it's crucial to use rigorous research methods to understand the real effects of substances like kratom. By avoiding assumptions and focusing on solid evidence, we can get a clearer picture of the risks and benefits involved.