Labena Slovenia’s Post

🚀 Cutting-Edge Innovation at Revvity Meets #Nobel-Winning Science! 🏆 This year’s The Nobel Prize in #Physiology or #Medicine was awarded to #VictorAmbros and #GaryRuvkun for their groundbreaking discovery of #microRNAs and their role in post-transcriptional gene regulation. This recognition highlights the transformational impact of #miRNAs in #medicine 🔬. 💥 At Revvity, I’m fortunate to work on the next-gen solutions that align with this vision—our #miRNA #NGSlibrary kits. I’m constantly blown away by the #precision and #efficiency of our kits, especially the #NEXTFLEX Small RNA Sequencing Kit V4. We’re not just following the trend; we’re setting the standard! 📈 ✨ What makes this kit a game changer? 🎯 Unparalleled sensitivity for low-input samples 🌍 Wide coverage for miRNA profiling across species ⚡️ Streamlined workflow = Faster & more reliable results 🧬 With these innovations, we’re helping scientists get closer than ever to quantitative insights at the miRNA level. 🔬 Check out our: NEXTFLEX Small RNA-Seq v4 Kit (https://lnkd.in/dT8Yq_JH) 🔗 Learn more about this year’s Nobel Prize: https://lnkd.in/dp5nVz5k #Innovation #NobelPrize #miRNA #NGS #REVVITY #GeneRegulation #Biotech #Precision

🚨 Exciting Research Update! 🚨 We are pleased to share that our latest research article, “Comprehensive alpha, beta, and delta cell transcriptomics reveal an association of cellular aging with MHC class I upregulation,” has been published in Molecular Metabolism. In this study, we examined the age-related changes in gene expression within alpha, beta, and delta cells. Our findings reveal a notable association between islet cell aging and the upregulation of MHC class I. This research was made possible through the collaborative efforts of many dedicated individuals. Thank you to everyone who contributed! For those interested in exploring our findings further, you can read the full article here: https://lnkd.in/ecHDzHiA Additionally, we developed an interactive tool to assess the expression levels of genes of interest in young, adult, and old alpha, beta, and delta cells. We hope this will be a valuable resource for the islet biology community. Check it out on our website: https://lnkd.in/eWqpEcb5 You can find the instructional video below. #DiabetesResearch #VUB #Research #Transcriptomics #MolecularMetabolism #Science

🌟 Exciting news! The 2024 Nobel Prize in Physiology or Medicine has been awarded for groundbreaking research involving 𝘊𝘢𝘦𝘯𝘰𝘳𝘩𝘢𝘣𝘥𝘪𝘵𝘪𝘴 𝘦𝘭𝘦𝘨𝘢𝘯𝘴 (𝘊. 𝘦𝘭𝘦𝘨𝘢𝘯𝘴), a vital organism that has significantly advanced our understanding of genetics, aging, toxicity and disease. At InVivo Biosystems, we take pride in leading the way in 𝘊. 𝘦𝘭𝘦𝘨𝘢𝘯𝘴 research. By harnessing its unique genetic similarities to humans, we drive innovation in drug discovery and development. Our patented gene editing technologies, part of our RapidGen™ preclinical platform, effectively bridge the gap between genetic insights and therapeutic breakthroughs. As we celebrate this prestigious accolade, we eagerly anticipate the transformative potential that 𝘊. 𝘦𝘭𝘦𝘨𝘢𝘯𝘴 hold for the future of research and medicine. 🧬✨ Discover more about the Nobel Prize and 𝘊. 𝘦𝘭𝘦𝘨𝘢𝘯𝘴 as a model organism here: https://lnkd.in/g7wdJ2B8 #NobelPrize #Celegans #InVivoBiosystems #Biotech #Innovation #DiseaseModeling #RNA #Research

Syncell is attending the Single-Cell Genomics Gordon Research Conference in Switzerland, ongoing until May 24th. This event explores how diverse cell types collaborate to enable tissue functions, with a focus on the intricate gene networks within cells. Technological advancements now allow for the detailed characterization of individual cells at the genomic scale within intact tissues. Single-cell and spatial omics methods, including proteomics, have emerged to measure various cellular properties with high spatial resolution. The conference unites life sciences and medical leaders with innovators in single-cell and spatial technologies to discuss recent advancements and their implications for diagnostics, therapeutics, and precision medicine. #GRC #SingleCellGenomics

Lifescience Network Lab Showcase Series: Episode 2 Join us as we highlight the groundbreaking work of Böttger Lab at LMU Munich – Ludwig-Maximilians-Universität München , led by the esteemed Prof. Dr. Angelika Böttger! Research Focus Areas: 1. Multicellularity and Evolution: Exploring how multicellular animals like Hydra vulgaris evolved from single-celled protozoans. 2. Notch Signaling: Investigating Notch signaling in Hydra for insights into stem cell differentiation and boundary formation. 3. Apoptosis Mechanisms: Examining caspase and Bcl-2 regulated apoptosis in Hydra to understand its evolutionary origins. 4. Oxygen and Gene Expression: Studying Jmjd6's role in mRNA splicing and its impact on development and oxygen dependency. Dive deeper into their innovative research here: https://lnkd.in/dKYw__Qf Poster credits: Smrutimayee Prusty #LifeScienceNetwork #ResearchShowcase #CellBiology #DevelopmentalBiology #HydraResearch #LMUMunich #ScientificResearch #EvolutionaryBiology

Now explore signaling pathways in 3D organotypic models combined with quantitative proteomics and phosphoproteomics approaches! https://lnkd.in/gDVSmrZV This latest research work by Zilu Ye, Hans H Wandall, and Sally Dabelsteen at Københavns Universitet - University of Copenhagen delve into the TGF-β pathway using CRISPR-Cas9 engineered human keratinocytes in a 3D organotypic skin model. ✨ This innovative approach combines genetic engineering with quantitative proteomics and phosphoproteomics mass spectrometry, providing unparalleled insight into human tissue signaling. 🌟 From embryonic development to disease progression, understanding these pathways is crucial. Also, the approach can be applied to other gene targets and 3D cell and tissue models. So click on the link 🔗, explore and adapt it to your research work! Bio-protocol sincerely thanks Philipp Wörsdörfer and Siyin (Hsih-Yin) Tan for reviewing this work. #CRISPR #Proteomics #TGFbeta #CellularSignaling Have a protocol that can contribute to scientific clarity and reproducibility ? Visit us at https://lnkd.in/dt_igxRi and explore publishing with Bio-protocol at https://lnkd.in/gR3QGYz6! #openaccess #reproducibility #lifesciences #research

Ingrida Olendraite, PhD will be attending Healthcare 2.0 Cell and Gene Therapy conference, in London, UK 🇬🇧, on October 14, 2024! This event, uniting experts from the UK, Europe, and beyond, focuses on practical strategies, upcoming challenges, and innovative solutions in healthcare. ☕️ Get in touch with Ingrida Olendraite, PhD if you would like to meet, connect and discuss how bioinformatics at VUGENE can support your research! #VUGENE #bioinformatics #research #healthcare

Greetings Everyone! 🌟 Breaking News: Nobel Prize in Medicine 2024! 🌟 A huge congratulations to Victor Ambros and Gary Ruvkun for receiving this year’s Nobel Prize in Medicine for their groundbreaking discovery of microRNA! 🧬 Their work has revolutionized our understanding of gene regulation and its role in disease. MicroRNAs, tiny but powerful molecules, control how genes are expressed, and this discovery has opened new doors in genetic research and therapeutic development. 🧠💡 From cancer treatment to heart disease, their discovery has had far-reaching implications, creating pathways for personalized medicine and novel drug therapies. 💊🧑⚕️ This marks a huge leap forward in biotechnology, showing how even the smallest elements of our biology can have an enormous impact on health and disease. As we celebrate this achievement, we’re reminded of how much is still possible in the world of life sciences. Their research continues to inspire scientists, researchers, and healthcare innovators to push the boundaries of what’s possible. 🔬🚀 Let’s take a moment to recognize the immense value of this work and look forward to the future breakthroughs it will inspire! #NobelPrize #Medicine #microRNA #HealthcareInnovation #LifeSciences #Pharma #Biotech #Genetics #PersonalizedMedicine #ScientificBreakthrough

Join our upcoming webinar on The Power of DNA Mutant Libraries: Accelerating Revolution in Research! 🚀 Our new informative webinar focuses on the revolutionary impact of DNA mutant libraries in biomedical research and development. Register here, https://bit.ly/3WGiqbn, to find out: 🧬 How DNA mutant libraries are revolutionizing biomedical research 🧬 The impact and application of DNA mutant libraries on gene and cell therapy (e.g., sgRNA library, CAR-/TCR-T libraries etc.), protein and antibody engineering and AI-driven drug design 🧬 Real-world case studies on applying DNA mutant libraries to enhance research and applications 🧬 The latest advancements and future possibilities in biomedical research Don't miss out on hearing from Dr Xing Gao, our Global Product Manager for Molecular Biology, and finding out how GenScript's years of experience and varied capabilities could help make your research easier! #Biotech #Research #DNA #Webinar #Innovation #ScienceTalk #freewebinar

RNAscope (by ACDbio a Bio-Techne brand) and COMET (by Lunaphore a Bio-Techne brand) seminar at UMR 7365 CNRS-UL IMoPA in Nancy today. With RNAscope You can visualize ANY gene expression (in) ANY tissues/cells/organoïds/whole-mount (in) ANY species Especially when you don't have (reliable) antibodies for your targets of interest (cytokines, GPCR, ion channels, splice variants isoforms, point mutations, ASO, siRNA, miRNA, lncRNA...) and to validate in situ transcriptomic datas (qPCR, scRNAseq, spatial transcriptomic) at the cellular and subcellular resolution. COMET is the first universal, end-to-end, spatial biology solution enable researchers to visualize up to 40+ proteins on a single tissue sections at the subcellular resolution. It is also possible to detect up to 12mRNA by RNAscope and 20+ proteins on the same sample with the platform. #RNAscope #RNA #acd #comet #lunaphore #multiomics #spatialtranscriptomic #spatialproteomic #spatialbiology #codetection