Rosario Ligresti MD FASGE

Apremilast Benefits and Risks in PsA Dr. Akhil Sood discusses abstracts 1466, 2583, 0598 and 2640 discussing the use of apremilast in PsA, presented at #ACR24. https://buff.ly/491Nc4b

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Maintenance dialysis for chronic kidney failure is associated with high mortality and frequent complications. This Review summarizes the pathophysiology, diagnosis, and management of dialysis-dependent chronic kidney failure. https://ja.ma/4gLfpzR

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Study of AutoAbs in 141 pts w/ systemic sclerosis overlap syndrome (SSc OS). Most common Abs: Ro-52, centromere (ACA) & anti-Scl-70. Scl-70 was assoc w/ ILD & SSc renal crisis (SRC); while ACA is protective factor of ILD. SRC & pulm HTN assoc w/ incr mortality

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Great work by my colleague Ankur Sethi MBBS FACC, published in Structural Heart and featured in Cardiovascular Business, that highlights the need for timely #TAVR in order to improve patient outcomes and reduce costs. Key findings: - Delaying TAVR in severe #aorticstenosis (AS) patients increases healthcare costs by $10,000 per year.** - Delays due to incomplete evaluations, referral issues, and systemic barriers lead to higher costs and increased mortality risk. [Cardiovascular Business Article](https://lnkd.in/g8-Fw3bZ.) [Publication] (https://lnkd.in/gJkU96tj) Rutgers Robert Wood Johnson Medical School Robert Wood Johnson University Hospital #Cardiology #TAVR #HealthcareEconomics #HeartHealth #StructuralHeart #PatientOutcomes #HeartValveDisease #HealthPolicy #ClinicalResearch #Echocardiography #Medicare

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JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management of patients with acute lower GI bleeding. https://ja.ma/3yAOFRa

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NSQIP-Pediatric criteria should be considered the gold-standard for severity assessment in children with appendicitis, finds cohort study of 80k+ children from 148 hospitals participating in NSQIP Pediatric. https://ja.ma/3XRxxiW

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Lowering serum urate to below 6 mg/dL in gout patients with chronic kidney disease stage 3 is not inferior to those who do not achieve this level with urate-lowering therapy. https://ja.ma/3CInyWj

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Review summarizes current evidence regarding the diagnosis and treatment of interstitial lung disease. https://ja.ma/3UcOfY6

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This cost-effectiveness study evaluated population-wide chronic kidney disease (CKD) screening at different ages and found that initiating screening at age 55, combined with SGLT2 inhibitors, was cost-effective. https://ja.ma/3UIrFrB

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Maintenance dialysis for chronic kidney failure is associated with high mortality and frequent complications. This Review summarizes the pathophysiology, diagnosis, and management of dialysis-dependent chronic kidney failure. https://ja.ma/3O2oO8X

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Preoperative use of GLP-1 receptor agonists in patients undergoing emergency surgery was not associated with a higher risk of postoperative respiratory complications compared with patients not using GLP-1 receptor agonists. https://ja.ma/3Uoz7It

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Excellent new pathway for management of acute HF hospitalization - from ACC. https://lnkd.in/eUu9fwtx

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Study results do not support the systematic use of a magnetic resonance imaging-guided treat-to-target strategy among patients with #RA who are in #remission. https://brnw.ch/21wJp8v

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This Special Communication discusses case-referenced consensus and evidence-based guidelines to inform clinical practice in unresectable locally advanced NSCLC. https://ja.ma/4cNAoz6

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In this comparative effectiveness study of patients with HFrEF requiring hemodialysis, sacubitril-valsartan therapy was associated with beneficial effects in all-cause mortality and all-cause hospitalization. https://ja.ma/4fK05Tw

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Helpful analysis - routine stress testing a year post heart attack is not helpful in predicting risk.

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Narrative review evaluates biological factors associated with multiple sclerosis in pediatric and late-onset populations. https://ja.ma/3MPVJx8

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A 2-surgeon team approach during ovarian cancer cytoreductive surgery that required a bowel resection lead to better outcomes and reduced anastomotic leak rate. Results suggest that team-based care improves surgical outcomes. https://ja.ma/40AcB2Q

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