Bicycle Therapeutics

As November comes to a close, we recognize our resident “Mo Bros” who spent the month supporting #Movember and raising awareness of men’s health issues, including #cancer. We are proud of our team for their commitment at work and in their personal lives to making a difference for patients.

At #SABCS24, we look forward to presenting updated clinical data in #breastcancer for our lead investigational therapy zelenectide pevedotin. We’ll also provide data updates for zele in other #cancers and host a webcast for investors to review the data. More info: https://bit.ly/4eN1B5u. 

Antimicrobial resistance is a great global health challenge. We are proud to contribute to research in this area, including our recent discovery and optimization of novel Bicycle® inhibitors of E. coli penicillin binding protein 3 (EcPBP3). With further development, this could lead to a new class of antimicrobial medicines. Read our pre-print publication here: https://bit.ly/3CDPevz. #WorldAMRAwarenessWeek

Members of our executive team will participate in a fireside chat at the Jefferies London Healthcare Conference next week. Tune in to hear how we’re using our Bicycle® technology platform to develop potential therapies for #cancer, and our milestones ahead. https://bit.ly/3O5dzg5

A warm welcome to the new hires who joined #TeamBicycle in October. We are happy to have you join our Development, Finance and Research teams! Learn more about our careers and culture: https://bit.ly/3TS7ZA8.

We recently held our Second Annual Macmillan Coffee Morning in support of Macmillan Cancer Support, one of the UK’s leading #cancer charities. Our team baked a slew of sweet treats for colleagues to enjoy with their coffee and tea, raising a total of £1,400 to help provide practical, emotional and financial support to those living with cancer.

A big congrats to our #TeamBicycle colleague Mike Hannay on his appointment to the BioIndustry Association (BIA) Board of Directors! 👏 We are proud to have him work alongside UK #biotech leaders to advance initiatives and foster an ecosystem that enable companies to grow and deliver world-changing #innovation. https://lnkd.in/e4mss7iK

Today we reported recent business progress and third quarter 2024 financial results. Read our press release here: https://bit.ly/3YvOr6S.

October marks Black History Month in the UK and Ireland. For our #TeamBicycle colleague Yasmin Kinobe MPH, the month provides an opportunity to reflect and reconnect with her family’s roots on the African continent. "My mother first stepped foot in the UK in her twenties with a scholarship to London School of Economics to study her master’s degree, and yet the odds were stacked against her as she came from humble beginnings. Having lost her mother at 3 years old and been brought up by extended relatives, it is in the UK she met my father in the 1980s who was also Ugandan but working and living in Nigeria as an expat. The rest was history as they married and had me and my sisters soon after. She maintained a career in social work for 30+ years and continues to give back to her community, opening a transit home for children in Uganda. "Growing up as Black British in London has been a rich experience, being surrounded by a melting pot of nationalities regardless of race. Within the Black community alone, we represent numerous countries from Africa and the Caribbean and have made great contributions to the Commonwealth. "This year, the theme of Black History Month is 'Reclaiming Narratives,' highlighting the part played by the Black community in British life and bringing untold histories to the forefront. Children across the nation are being educated on the Windrush generation of emigrants from Jamaica who were brought to the UK in the 1940s, and Mary Seacole who rivalled Florence Nightingale in her assistance to wounded military personnel during the Crimean war. These were things I was never taught in school, so the efforts made to recognise and build pride as well as awareness are truly admirable."

Today we announced first human imaging data for our Bicycle Radionuclide Conjugate® targeting MT1-MMP, a novel tumor antigen, and outlined our strategy to develop next-generation #radiopharmaceuticals. Read more here: https://bit.ly/3UlNAoe.