Amy Schumer on Reaction to Her Looks amid Health Scare: Supporters 'Are Not Going to Care If My Face Is Puffy'

Amy Schumer is responding to the comments she received on her looks earlier this year while dealing with a hormonal disorder.

In an interview with Variety, the actress and comedian opened up about seeing messages about her “puffy” face, admitting that it created some insecurities. However, the 42-year-old said she was quickly able to get over the internet chatter.

“The people who like me are not going to care if my face is puffy,” she told the outlet. “Everyone has moments of self-doubt. I rose up and was like, ‘F--- it, let’s go.’ ”

Schumer revealed in February 2024 that she was diagnosed with Cushing syndrome.  

The condition occurs when too much cortisol (the primary stress hormone) is inside one's body for a long time, according to the Mayo Clinic. Possible symptoms include weight gain, high blood pressure and bone loss. Treatment can involve medication, radiation therapy or surgery.

The I Feel Pretty star shared details about her health just days after fans began questioning why she had a "puffier" face during her promo tour for season 2 of Life & Beth.

"While I was doing press on camera for my Hulu show, I was also in MRI machines four hours at a time, having my veins shut down from the amount of blood drawn and thinking I may not be around to see my son grow up,” Schumer said at the time. “So finding out I have the kind of Cushing that will just work itself out and I'm healthy was the greatest news imaginable.”

Never miss a story — sign up for PEOPLE's free daily newsletter to stay up-to-date on the best of what PEOPLE has to offer, from celebrity news to compelling human interest stories.

The comedian said that "having the internet chime in" on her appearance helped her know something was wrong.

"It has been a crazy couple [of] weeks for me and my family," she said. "Aside from fears about my health, I also had to be on camera having the internet chime in. But thank God for that. Because that's how I realized something was wrong."

When asked why she was open to sharing her "personal medical information," Schumer said she wants to "advocate for women's health."

"The shaming and criticism of our ever-changing bodies is something I have dealt with and witnessed for a long time," she explained. "I want so much for women to love themselves and be relentless when fighting for their own health in a system that usually doesn't believe them."

Schumer expressed that her diagnosis "is a good example of the fact that we never know what is going on with someone."

"Everyone is struggling with something," she added. "Maybe we can all be a little kinder to each other and ourselves."