Yoran M. Hummel

Yoran M. Hummel

Groningen, Groningen, Nederland
2K volgers Meer dan 500 connecties

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Over 20 year of experience in healthcare and echocardiography.
Obtained a PhD in the…

Artikelen van Yoran M.

  • Big data in medicine and privacy: Feeling uncomfortable yet?

    Big data in medicine and privacy: Feeling uncomfortable yet?

    Some time ago, most of us witnessed Mark Zuckerberg (CEO of Facebook) do a testimony before US congress on the delicate…

    2 commentaren
  • EuroEcho 2018, Milan-Italy

    EuroEcho 2018, Milan-Italy

    Super excited and honored that I was invited to give 2 lectures at EuroEcho in December 2018 in Milan on my favorite…

    3 commentaren

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Publicaties

  • Echocardiographic estimation of left ventricular and pulmonary pressures in patients with heart failure and preserved ejection fraction: a study utilizing simultaneous echocardiography and invasive measurements.

    Eur J Heart Fail

    AIMS:

    Although echocardiography is generally used for the diagnosis of heart failure with preserved ejection fraction (HFpEF), invasive measurements of filling pressures are the gold standard. Studies simultaneously performing echocardiography and invasive measurements in HFpEF are sparse.

    METHODS AND RESULTS:

    Invasive haemodynamic and echocardiographic measurements were simultaneously performed in 98 patients with heart failure New York Heart Association class ≥II, left…

    AIMS:

    Although echocardiography is generally used for the diagnosis of heart failure with preserved ejection fraction (HFpEF), invasive measurements of filling pressures are the gold standard. Studies simultaneously performing echocardiography and invasive measurements in HFpEF are sparse.

    METHODS AND RESULTS:

    Invasive haemodynamic and echocardiographic measurements were simultaneously performed in 98 patients with heart failure New York Heart Association class ≥II, left ventricular ejection fraction (LVEF) ≥45%, and suspected pulmonary hypertension on a previous echocardiogram. Multivariable linear regression analyses were used to establish echocardiographic predictors of pulmonary artery wedge pressure (PAWP), left ventricular end-diastolic pressure (LVEDP), and mean pulmonary arterial pressure (mPAP). Mean age of the study patients was 74 ± 9 years, 68% were female, mean LVEF was 57 ± 5%, and 30% had atrial fibrillation at the time of measurement. Mean PAWP, LVEDP and mPAP were 17.2 ± 6.2, 16.7 ± 5.8 and 30.9 ± 10.2 mmHg, respectively. Isovolumetric relaxation time (IVRT) and left atrial reservoir strain could moderately estimate PAWP (r = 0.656; P < 0.001). LVEDP was only modestly predicted by IVRT and right ventricular wall thickness (r = 0.548; P < 0.001). Surprisingly, a low correlation was found between E/e'mean and PAWP (r = 0.240; P = 0.019), E/e'mean and LVEDP (r = 0.081; P = 0.453). Correlation coefficients were similar in patients with and without atrial fibrillation.

    CONCLUSION:

    In patients with HFpEF, echocardiographic measurements, including the E/e' ratio, have a poor to moderate predictive value for the estimation of invasively acquired LVEDP and PAWP. This limitation should be taken into account for the diagnosis and evaluation of patients with HFpEF.

    Publicatie weergeven
  • Book chapter diastolic LV function - 'praktische echocardiografie'

    Authored text book chapter on diastolic Left ventricular function in 'praktische echocardiografie' 3rd press

  • Clinical examination, critical care ultrasonography and outcomes in the critically ill: cohort profile of the Simple Intensive Care Studies-I.

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    Clinical examination, critical care ultrasonography and outcomes in the critically ill: cohort profile of the Simple Intensive Care Studies-I.

    Hiemstra B, Eck RJ, Koster G, Wetterslev J, Perner A, Pettilä V, Snieder H, Hummel YM, Wiersema R, de Smet AMGA, Keus F, van der Horst ICC; SICS Study Group.

    BMJ Open. 2017 Sep 27;7(9):e017170. doi: 10.1136/bmjopen-2017-017170

  • Correlation with invasive left ventricular filling pressures and prognostic relevance of the echocardiographic diastolic parameters used in the 2016 ESC heart failure guidelines and in the 2016 ASE/EACVI recommendations: a systematic review in patients wi

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    Correlation with invasive left ventricular filling pressures and prognostic relevance of the echocardiographic diastolic parameters used in the 2016 ESC heart failure guidelines and in the 2016 ASE/EACVI recommendations: a systematic review in patients with heart failure with preserved ejection fraction.


    Nauta JF, Hummel YM, van der Meer P, Lam CSP, Voors AA, van Melle JP.

    Eur J Heart Fail. 2018 Sep;20(9):1303-1311. doi: 10.1002/ejhf.1220. Epub 2018 Jun 7

  • Diabetes Mellitus and Right Ventricular Dysfunction in Heart Failure With Preserved Ejection Fraction.

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    Diabetes Mellitus and Right Ventricular Dysfunction in Heart Failure With Preserved Ejection Fraction.


    Gorter TM, Streng KW, van Melle JP, Rienstra M, Dickinson MG, Lam CSP, Hummel YM, Voors AA, Hoendermis ES, van Veldhuisen DJ.

    Am J Cardiol. 2018 Mar 1;121(5):621-627. doi: 10.1016/j.amjcard.2017.11.040. Epub 2017 Dec 11

  • Diastolic Dysfunction is Common in Survivors of Pediatric Differentiated Thyroid Carcinoma.

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    Diastolic Dysfunction is Common in Survivors of Pediatric Differentiated Thyroid Carcinoma.


    Klein Hesselink MS, Bocca G, Hummel YM, Brouwers AH, Burgerhof JGM, van Dam EWCM, Gietema JA, Havekes B, van den Heuvel-Eibrink MM, Corssmit EPM, Kremer LCM, Netea-Maier RT, van der Pal HJH, Peeters RP, Plukker JTM, Ronckers CM, van Santen HM, van der Meer P, Links TP, Tissing WJE.

    Thyroid. 2017 Dec;27(12):1481-1489. doi: 10.1089/thy.2017.0383.
    PMID: 29132262

  • Effect of isolated ultrafiltration and isovolemic dialysis on myocardial perfusion and left ventricular function assessed with 13N-NH3 positron emission tomography and echocardiography.

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    Effect of isolated ultrafiltration and isovolemic dialysis on myocardial perfusion and left ventricular function assessed with 13N-NH3 positron emission tomography and echocardiography.


    Assa S, Kuipers J, Ettema E, Gaillard CAJM, Krijnen WP, Hummel YM, Voors AA, van Melle JP, Westerhuis R, Willemsen A, Slart RHJA, Franssen CFM.

    Am J Physiol Renal Physiol. 2018 Mar 1;314(3):F445-F452. doi: 10.1152/ajprenal.00368.2017. Epub 2017 Nov 8.
    PMID: 29117996

  • Markers of left ventricular systolic dysfunction when left ventricular ejection fraction is normal.

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    Markers of left ventricular systolic dysfunction when left ventricular ejection fraction is normal.


    Nauta JF, Jin X, Hummel YM, Voors AA.

    Eur J Heart Fail. 2018 Dec;20(12):1636-1638. doi: 10.1002/ejhf.1326. Epub 2018 Oct 17. Review

  • Right Heart Dysfunction in Heart Failure With Preserved Ejection Fraction: The Impact of Atrial Fibrillation.

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    Right Heart Dysfunction in Heart Failure With Preserved Ejection Fraction: The Impact of Atrial Fibrillation.


    Gorter TM, van Melle JP, Rienstra M, Borlaug BA, Hummel YM, van Gelder IC, Hoendermis ES, Voors AA, van Veldhuisen DJ, Lam CSP.

    J Card Fail. 2018 Mar;24(3):177-185. doi: 10.1016/j.cardfail.2017.11.005. Epub 2017 Nov 29

  • What have we learned about heart failure with mid-range ejection fraction one year after its introduction?

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    What have we learned about heart failure with mid-range ejection fraction one year after its introduction?


    Nauta JF, Hummel YM, van Melle JP, van der Meer P, Lam CSP, Ponikowski P, Voors AA.

    Eur J Heart Fail. 2017 Dec;19(12):1569-1573. doi: 10.1002/ejhf.1058. Epub 2017 Oct 24. Review.

    PMID: 29067761

Talen

  • English

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  • Dutch

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  • German

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