DTU Biotech Lifelong Learning

Over the next two years, we are adding cutting-edge courses focusing on Biosynthesis, Mass Spectrometry, and Proteomics to the Biotech Lifelong Learning course catalogue. Here DTU researchers will share the latest advances in these areas and showcase how they can be applied in optimizing biotech processes. Scott Jarmusch, Assistant Professor at DTU Bioengineering is an expert on Mass spectrometry (MS) and one of the course instructors of the new courses, and he shares how MS is revolutionizing the way we can analyze molecular interactions: “MS acts as a molecular scale, offering unparalleled precision in measuring chemical compounds. Whether identifying contaminants in environmental samples or unravelling the chemical ecology of microbial interactions, MS provides insights that were previously out of reach. My research focus on a group of bacteria called Streptomyces, the main source of antibiotics for the last 100 years. But instead of studying them as drug discovery candidates, I investigate how chemical compounds are used in interactions between microbes. By using mass spectrometry and other omics techniques we can ask questions like: If two microbes are near each other, how are they communicating? And what compounds are they using to communicate?  And one of the most powerful techniques we have is something called mass spectrometry imaging (MSI) which enables us to spatially visualize compound distributions and thereby to pinpoint how different compounds drive microbial interactions. The new frontier in biotech is the integration of multi-omics data. Traditionally, omics data—such as transcriptomics, proteomics, and metabolomics—have been analyzed independently and combined post-analysis. Now, we’re integrating the data points. By linking for instance, an upregulated gene in one dataset to an increased compound production in another, we can identify key genes responsible for specific biochemical pathways. This integrative approach is more prevalent in medical research, but its application in industrial biotechnology is expanding, promising to unlock new levels of functional understanding. Mass spectrometry, proteomics, and biosynthesis aren’t just theoretical tools—they are highly practical solutions for industry challenges. Companies can leverage MS to monitor biomanufacturing processes with unmatched sensitivity, detecting products and byproducts in real-time. These techniques also provide essential insights for enzyme discovery, optimization, and the development of sustainable bioprocesses. I’m looking very much forward to helping participants from the industry gain foundational knowledge in MS, proteomics, and biosynthesis to address their unique challenges.” #LifelongLearning #Biotechnology #MassSpectrometry #Proteomics #Biosynthesis #Innovation #Sustainability

Are you incorporating all three pillars of sustainability into your assessments and decision-making? Not many companies are currently doing so. But this approach represents the future of measuring the sustainability performance of bio-based technologies. In this video experts from the Sustainability Innovation Office at DTU - Technical University of Denmark introduce the three pillars of sustainability and highlight some of the quantifiable key indicators you will learn to identify and integrate in your assessments if you join the DTU Biotech Lifelong learning course. 🌿 Sustainability Assessment of Bio-Based Products, 4-6 March 2025 at DTU. Learn how to measure economic, environmental and social impact of bio-based products. Course Instructors: Sumesh Sukumara, Catharina Wolff von Bülow, Samir Meramo, Michael Hauschild, Eleonora Pasutto, Ólafur Ögmundarson, PhD, & Anders Bjørn 👉 For more information about the course visit: https://lnkd.in/dB6URDpE Limited seats available! #Sustainability #Biomanufacturing #LCA #COURSE #Lifelonglearning

"Filamentous fungi already play an important role in biomanufacturing, but I believe it could be even greater, says Jakob Blæsbjerg Hoof Associate Professor at DTU Bioengineering and head of the world-class fungal collection, the IBT Culture Collection. “With advancements in sequencing, metabolomics and proteomics technologies, automation solutions and new genetic tools, the time required to utilize a new fungus for industrial purposes has drastically decreased, opening up completely new possibilities”, Blæsbjerg explains. “I started at DTU - Technical University of Denmark to become a brewmaster, but when I met filamentous fungi and understood how much they could be used for and how fascinating they are, I ended up with a PhD in Aspergillus nidulans, and I've worked with filamentous fungi ever since. Some products are easier to produce in filamentous fungi because of their physiology. However, controlling this physiology is essential to fully leverage their behavior and production potential. As complex multicellular organisms, they branch out to explore all possible resources in a territory. To consume, they secrete enzymes that degrade complex materials. Additionally, some fungi produce active molecules that may protect their environment or act as signals. You need to understand the benefits of fungal biology—why they are so efficient at what they do—as well as their challenging characteristics. This helps determine whether to use a particular fungus, or whether modifications are necessary. These are some of the topics we cover in our Industrial Mycology course. Our course includes sessions on: 👉 Fermentation Technology 👉 Strain Engineering 👉 Fungal Physiology 👉 Fungal metabolites and products 👉 Fungal applications We also provide fundamental lab training in observing fungi both macroscopically and microscopically because identifying the fungus is, of course, the first step. https://lnkd.in/eNT_y3Y7 At DTU Bioengineering, we house a unique collection of fungi isolated by DTU researchers from various environments like soil, buildings, food products, and geographical locations in Denmark and worldwide. This collection includes over 38,000 fungal isolates/strains, and we continuously expand it. We're open to collaboration with both academia and industry to harness this incredible resource. We can explore applications in contaminant degradation, pathogen challenges, or the utilization of industrial side streams. The possibilities are practically limitless, and that's what makes this work so exciting.” Visit the IBT Culture Collection at: https://lnkd.in/d6N4j4TK or directly at: https://dtu.bio-aware.com

DTU - Technical University of Denmark's 2025 DTU Biotech Lifelong Learning course program is now live on our web shop! Explore the fundamentals of bioprocessing, upstream, digitalization, finance, and more. Elevate your career in biotech with our short courses (1-5 days) that are designed for industry professionals. We also offer tailor-made courses to meet your company's specific needs. Join us in shaping the future of biotechnology. Enroll now and stay ahead in your field: https://lnkd.in/exEsSujS Don't miss out on this opportunity for professional growth! #Biotech #Biomanufacturing #LifelongLearning #Sustainability #Highereducation

“The practical part of the course was very relevant for me. Installing and inoculating a bioreactor, calibrating probes and performing welds I don’t usually get to do as a scientist, but it's incredibly helpful to understand these processes when writing MPRs and supporting technicians in production”,  says Emilie Kjellerup Bryde Petersen from AGC Biologics, when asked about her experience in the Introduction to Mammalian Bioprocessing course at DTU - Technical University of Denmark. “I am working as an upstream scientist in Manufacturing Product Support. I am responsible for batch production, including creation of MPRs and supporting our technicians when facing challenges in production.   My motivation to join this course was the opportunity to gain hands-on experience in a training environment. The combination of theory and lab work was especially appealing.   The course was very well organized, blending lectures with practical work and allowing time for questions and discussions. This approach was beneficial not only in terms of research but also in understanding how research can be scaled up for manufacturing. I will apply what I learned on the course in my daily work, improving my ability to support and guide the technicians when facing challenges in the production.   It was also fascinating to learn about new research in the field, as well as potential challenges in manufacturing and how they might be mitigated in the future.” Learn more about the course: “Introduction to Mammalian Bioprocessing”:  https://lnkd.in/d3VN-F-y #MammalianCells #Fermentation #biopharmaceuticals #Proteins #handson

Our 2025 course line-up is here! Whether you're looking to expand your skills in biomanufacturing, digitalization, upstream processing, or bio-based product sustainability, we have something tailored for every biotech professional. New 2025 Courses Include: - Biosynthesis of Natural Products – January 13-17 - Bio-Based Technologies for Waste and Side Stream Valorization – 15-17 September - Microbial Biofilm Techniques – August 2025 Secure your spot now and take the next step in your biotech career! Explore the full schedule & course details: https://lnkd.in/ddUP_Cjb #Biotech #LifelongLearning #ProfessionalDevelopment #DTU #2025

Join Our November Biotech Seminar (free event)! Don't miss the next seminar of the Autumn 2024 Biotech Seminar Series, a collaboration between DTU Biotech Lifelong Learning and NC State BTEC! 🗓️ Date & Time: 14 November 2024 @ 15:00 CEST // 09:00 EST 📍 Location: Online via Zoom 💡 Topic: " Research-Centric Data Management: Enhancing Infrastructure and Skills" 👨🔬 Speaker: Dr Ajuna Azad, Research Data Manager, DTU Bioengineering This seminar is free to attend and open to everyone! Register here: https://lnkd.in/ecV4aNQu The Biotech Seminar Series is organized under the AIM-Bio Program, a collaboration between DTU - Technical University of Denmark and North Carolina State University (NC State BTEC, DTU Bioengineering and DTU Chemical and Biochemical Engineering), generously funded by the Novo Nordisk Foundation.

Our latest advertorial in Ingeniøren dives into the hands-on experience provided by DTU - Technical University of Denmark’s “Hands-On Introduction to Biomanufacturing Operations” course. This unique 3-day course, held at DTU Chemical and Biochemical Engineering’s pilot plant, allows participants to get involved in every step of modern biotech production—from operating bioreactors to practical fermentations.   Expert instructors like John Woodley, Julian Kager, Gerd Seibold and Krutika Bavishi, Ph.D. ensure that course participants gain both theoretical knowledge and practical skills, offering an unparalleled opportunity for professionals outside of direct production roles to understand biotech processes up close.   Read the advertorial here: https://lnkd.in/dxS-evTE   🗓 Next course dates: 11-13 November 2024 and 17-19 February 2025 ⏳ Availability: Limited seats remaining—act fast! 🔗 Register here: https://lnkd.in/dHdVWugR   This DTU - Technical University of Denmark course was developed in the framework of the AIM-Bio Project, in collaboration between DTU Bioengineering, and DTU Chemical and Biochemical Engineering, and NC State BTEC. The project is funded by the Novo Nordisk Foundation.   #Biomanufacturing #Biotech #LifelongLearning #ProfessionalDevelopment #HigherEducation #ContinuingEducation

💡 Why you need to understand mammalian bioprocessing With more complex biopharmaceuticals coming into the market, mammalian cells have become essential in biomanufacturing today. These therapeutic proteins are designed to closely mimic molecules naturally found in the human body and mammalian cells are uniquely capable of producing proteins that match those, thanks to their ability to perform specific post-translational modifications, such as glycosylation. While efforts are underway to engineer yeast and bacterial cells to do the same, mammalian cells remain the go-to system for these critical modifications. This is why we have developed the course "Introduction to Mammalian Bioprocessing". Whether you’re transitioning from bacterial or yeast fermentation or working adjacent to the field, this course offers a good foundation. It provides hands-on exposure to the machinery and processes while covering the unique challenges of working with mammalian cells compared to more traditional fermentation methods. 🔗 See more course details at: https://lnkd.in/d3VN-F-y Participants will meet course lead Lasse Ebdrup Pedersen, and we asked him to share some of the new exciting advancements in the field: “One of the exciting new developments is the rise of cell therapy, where the cells themselves become the therapeutic product like T-cell therapy for cancer. Instead of harvesting the substances secreted by the cells, these therapies use the cells themselves. This brings with it unique challenges. The methodologies for growing, optimizing, and handling these cells are becoming increasingly vital. It’s relatively early stages still evolving from an academic pursuit to an industrial one, but companies are waking up to the need for scalable manufacturing processes to ensure these potentially life-saving treatments reach a broad patient population. Another focus of my research at DTU Bioengineering is on improving the stability of the mammalian cells used in drug production. The cells we most commonly use, like the #CHO cells, have been industry standards for decades. While they are highly adaptable, they are also quite unstable, which means that after introducing a gene into billions of cells, each one can behave differently. This variability leads to long processes of selecting the best cells and optimizing the conditions for production. However, recent advancements in our research have shown promising ways to reduce this variability, ensuring that cells consistently produce the same results. This not only accelerates the development of bioprocesses but also offers the potential for a more streamlined path from gene introduction to drug production. #Biomanufacturing #MammalianCells #CellTherapy #Bioprocessing #PharmaceuticalInnovation #LifelongLearning

We had the privilege of attending the The Fermentation Based Biomanufacturing Initiative Symposium on October 22nd, where our course instructors actively engaged with sessions on cutting-edge topics such as: ▪ Scaling, Gradients, and Heterogeneity ▪ Innovation in Biomanufacturing ▪ Non-conventional Biomanufacturing It was truly inspiring to witness leading scientists from academia and industry come together, all driven by a shared passion for advancing fermentation and biomanufacturing. The day was filled with insightful discussions that reinforced how essential collaboration is for pushing innovation in this rapidly evolving field. We’re excited to take these insights back to our courses and continue shaping the future of biomanufacturing!