2chain of Disease

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Chain

of
Disease
Learning Objectives
 Discuss chain of infection and different types of mode of
transmission
 Define isolation precautions and describe different types
isolation precautions.
 Describe standard precautions procedures and conditions
under which to use standard precautions
 Describe contact precautions and conditions under which
to use contact precautions.
 Describe conditions under which to use droplet
precautions.
 Describe conditions under which to use airborne
precautions.
Mode of Transmission
A microorganism may be spread by a single
or multiple routes.
 Contact, direct or indirect
 Droplet
 Airborne
 Vector-borne (usually arthropod) and
 Common environmental sources or vehicles
- includes food-borne and waterborne,
medications e.g., contaminated IV fluids
Contact transmission
1. Direct-contact
 Direct body surface-to-body surface contact and
 Physicaltransfer of microorganisms between a
susceptible host and an infected or colonized
person.
2. Indirect-contact
 Contactof a susceptible host with a contaminated
intermediate object, usually inanimate, such as
contaminated instruments, needles, or dressings,
or contaminated hands or gloves
Droplet transmission
Droplet generation
coughing,
sneezing,
talking,
 procedures
such as suctioning and
bronchoscopy
Droplet transmission
Droplet deposited on the host’s conjunctivae,
nasal mucosa, or mouth.
Airborne transmission
 Small-particleresidue {5µm or
smaller} of evaporated droplets
containing microorganisms
 Suspended in the air for long
periods of time
 Dispersed by air currents
 Inhaledby a susceptible host
within the same room or over a
longer distance
Definition of Isolation Precautions
Source: Mosby's Medical Dictionary, 8th edition. ©
2009, Elsevier.
Special precautionary measures,
practices, and procedures used in
the care of patients with
contagious or communicable
diseases
7 Categories Recommended in Isolation
 1. Strict Isolation – to prevent highly contagious or virulent
infections.
 2. Contact Isolation – to prevent the spread of infection
primarily by close or direct contact.
 3. Respiratory Isolation-to prevent transmission of
infectious diseases over short distances through the air.
 4. TB Isolation- for TB patients with positive smear or with
chest-xray which strongly suggests active tuberculosis.
 5. Enteric Isolation –is for infectious with direct contact
with feces.
7 Categories Recommended in Isolation
Drainage/ Secretion precaution- to
 6.

prevent infections that are


transmitted by direct or indirect
contact with purulent materials or
drainage from an infected body site.
7. Universal Precaution – which is
applied when handling blood and body
fluids.
1996 CDC
Guidelines for
Isolation
Precautions in
Hospitals
Hospital infection
control practices
advisory
committee
(HICPAC)
Fundamentals of isolation precautions
 Handwashing and gloving
 Personal protective equipment :
 Masks, respiratory protection, eye protection,
face shields, gowns and protective apparel
 Patient-care equipment and articles
 Linen and laundry
 Routine and terminal cleaning
 Patient placement
 Transport of infected patients
Isolation Precautions
Types of Isolation
Precautions

Standard precautions
Transmission-based

precautions
Contact precautions
Airborne precautions
Droplet precautions
Definition of standard precautions

 Apply to all patients receiving care in hospitals


regardless of their diagnosis or presumed
infection status.
 Apply to (1) blood; (2) all body fluids, secretions,
and excretions except sweat, regardless of
whether or not they contain blood; (3) nonintact
skin; and (4) mucous membranes.
Standard Precaution - Hand hygiene
 Handwashing with either plain or antiseptic
 containing soap and water, and use of alcohol-based
 products (gels, rinses, foams) that do not require the
 use of water

 Perform hand hygiene:


 Before and after patient contact
 After removing gloves or any other PPE item
 Aftertouching blood, body fluids, secretions, excretions,
and contaminated items, whether or not gloves are worn
Standard precautions
Personal protective equipment (PPE)
 The selection of PPE based on
 The nature of patient interaction and/or
 The likely mode(s) of transmission
 Designated containers for used disposable or
reusable PPE should be placed in a convenient to
the site of removal
 Handhygiene is always the final step after
removing and disposing of PPE
Standard precautions - prevent HCWS
Exposure to Bloodborne Pathogens
 Preventneedles and other sharps
instrument injuries
 Prevent mucous membrane exposures
 Safe
work practices and PPE to protect
mucous membranes and non-intact skin
Standard precautions: Environmental
measures
 Cleanand disinfect non-critical surfaces in
patient-care areas are part of SP.

 Cleanand disinfect all frequently touched


surfaces in patient-care areas

 EPA-registered disinfectants or detergents


Standard precautions: Patient Care
equipment and instruments/devices

 Cleanand
maintain medical
equipment and
instruments/devi
ces according to
the
manufacturers’
instructions
Standard Precautions: Textile and
Laundry
 Key principles for handling of soiled laundry:

 Don’t
shaking items or handle them in any way that
may aerosolize infectious agents

 Avoid contact with one’s body and personal clothing

 Contain soiled items in a laundry bag or designated


bin
Standard Precautions – 2007 guidelines
for isolation precautions

 Three new elements added to standard precautions:

 Respiratory hygiene/cough etiquette

 Safe injection practices

 Use of masks for insertion of catheters or injection into


spinal or epidural areas
Respiratory hygiene and cough
etiquette
 Three elements include:
 Educate healthcare workers, patients, and visitors
 Post signs in appropriate language(s)
 Source control measures:
 Cover the nose/mouth when coughing or sneezing
 Use tissue paper respiratory secretions and dispose in the waste
receptacle
 Perform hand hygiene after contact with respiratory secretions and
contaminated objects
 Place a surgical mask on the coughing person when tolerated and
appropriate
 Spatial separation, ideally >3 feet
Safe injection practices
 Largeoutbreaks of HBV and HCV among
patients in the United States
 The primary breaches
 Reinsertion of used needles into a multiple-
dose vial or solution container (e.g., saline
bag)
 Useof a single needle/syringe to
administer intravenous medication to
multiple patients.
Masks for special lumbar puncture
procedures or central line placement
 Facemasks limit dispersal of oro-
pharyngeal droplets during:
 central venous catheters placement
 Placement of catheter or injection to
epidural space
 HICPAC recommends the use of a face mask
when placing a catheter or injection to
epidural space.
TRANSMISSION-BASED PRECAUTIONS
TRANSMISSION-BASED PRECAUTIONS -
Patient Placement
 Single
patient rooms - always indicated for
patients placed on airborne precautions
and preferable for those who require
contact of droplet precautions

 Cohort patients with same organism


TRANSMISSION-BASED PRECAUTIONS -
Management of visitors
 Visitorsas sources of healthcare associated
infections – e.g., pertussis, influenza,
tuberculosis
 Cough etiquette
 Use of barrier precautions by visitors
 Educate patients and family members
 Follow signs for isolation precautions
TRANSMISSION-BASED PRECAUTIONS -
Contact Precautions
Infections
 spread by direct or indirect contact with patients or
patient-care environment – shigellosis, C. difficile, MRSA
Limit patient movement

Private/SINGLE room or cohort with patients with same infection

Wear disposable gown and gloves when entering the patient room

Remove and discard used disposable gown and gloves inside the

patient room
Wash hands immediately after leaving the patient room

Clean patient room daily using a hospital disinfectant, with

attention to frequently touched surfaces (bed rails, bedside
tables, lavatory surfaces, blood pressure cuff, equipment
surfaces)
Use dedicated equipment if possible (e.g., stethoscope)

Contact Precautions cont.
GLOVES
 Use gloves when entering the room.
 Change gloves after contact with infective material.
 Remove gloves before leaving the room.
 Wash hands or use appropriate gel after glove removal.
 Do not touch infective material or surfaces with hands.
 Clean, non-sterile gloves are usually adequate.

GOWN
 Use protective gown when entering the room if
 direct contact with patient or
 potentially contaminated surfaces or
 equipment near patient is anticipated or
 if the patient has diarrhea or
 colostomy or wound drainage that is not covered by a dressing.
Droplet Precautions
 Reduce the risk of transmission by large particle droplets
(larger than 5 m in size).

 Requires close contact between the source person and the


recipient

 Droplets usually travel 3 feet or less

 E.g.,influenza, rubella, parvovirus B19, mumps, H.


influenzae, and Neisseria meningitidis
Droplet Precautions
 A private/single room or

 Cohort with patient with active infection with same


microorganism

 Use a mask when entering the room and definitely if within 3


feet of patient

 Limit movement and transport of the patient. Use a mask on


the patient if they need to be moved and follow respiratory
hygiene/cough etiquette

 Keep at least 3 feet between infected patient and visitors


Airborne Precautions
 Tuberculosis, measles, varicella

 Place the patient in an airborne infection isolation room (AIIR)

 Pressure should be monitored with visible indicator

 Useof respiratory protection (e.g., fit tested N95 respirator) or powered air-
purifying respirator (PAPR) when entering the room

 Limit
movement and transport of the patient. Use a mask on the patient if they
need to be moved

 Keep patient room door closed.

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