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    Immuno-Serology & Blood Banking Case Study

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    Romie Solacito
    This case report describes a 20-year old female who presented with bruising, joint pain, fatigue, and tingling fingers. Her lab work showed low platelet count, hemoglobin and hematocrit along with a positive ANA test. She was given a platelet transfusion which increased her count. Further testing showed no evidence of hepatitis B but supported a diagnosis of systemic lupus erythematosus given her symptoms and lab abnormalities. SLE can cause low platelet and blood cell counts due to autoimmune destruction.

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    Immuno-Serology & Blood Banking Case Study

    Uploaded by

    Romie Solacito
    295 views8 pages
    This case report describes a 20-year old female who presented with bruising, joint pain, fatigue, and tingling fingers. Her lab work showed low platelet count, hemoglobin and hematocrit along with a positive ANA test. She was given a platelet transfusion which increased her count. Further testing showed no evidence of hepatitis B but supported a diagnosis of systemic lupus erythematosus given her symptoms and lab abnormalities. SLE can cause low platelet and blood cell counts due to autoimmune destruction.

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    Medical Technology: Internship Program

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    This case report describes a 20-year old female who presented with bruising, joint pain, fatigue, and tingling fingers. Her lab work showed low platelet count, hemoglobin and hematocrit along with a positive ANA test. She was given a platelet transfusion which increased her count. Further testing showed no evidence of hepatitis B but supported a diagnosis of systemic lupus erythematosus given her symptoms and lab abnormalities. SLE can cause low platelet and blood cell counts due to autoimmune destruction.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    295 views8 pages

    Immuno-Serology & Blood Banking Case Study

    Uploaded by

    Romie Solacito
    This case report describes a 20-year old female who presented with bruising, joint pain, fatigue, and tingling fingers. Her lab work showed low platelet count, hemoglobin and hematocrit along with a positive ANA test. She was given a platelet transfusion which increased her count. Further testing showed no evidence of hepatitis B but supported a diagnosis of systemic lupus erythematosus given her symptoms and lab abnormalities. SLE can cause low platelet and blood cell counts due to autoimmune destruction.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
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    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE

    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1


    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    CASE REPORT
    A 20-year old female consulted her
    physician because of the presence of
    pigment-sized reddish-purple spots on her
    lower legs and on her face these physical
    symptoms was accompanied with weight
    loss, joint pain, headache, severe fatigue
    and her fingers turning white and tingling
    when cold.
    Physical Examination
    Temperature 37 Celsius Normal
    Pulse Rate 115 BPM Increased
    Blood Pressure 140/90 Increased
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    HEMATOLOGY REPORT
    Hemoglobin 82 (120 – 140) Low
    The physician requested for Hematocrit 0.22 (0.37 – 0.43) Low
    White Blood Cells 6.9 (5 - 10) Normal
    Complete Blood Count with Platelet Count, - Neutrophil 0.78 (0.55 – 0.65) High
    Reticulocyte Count, RBC Indices, Chemistry - Lymphocyte 0.13 (0.25 – 0.35) Low
    Test – Albumin, BUN, Creatinine, SGPT, - Eosinophil 0.01 (0.02 – 0.05) Low
    - Monocyte 0.07 (0.02 – 0.05) High
    Electrolytes, and Bilirubin, Coagulation Test - Basophil 0.01 (0.0 – 0.06) Normal
    – PT and APTT and Immunology – ANA, and Platelet Count 14 (150 - 500) Low
    DsDNA. Reticulocyte Count 0.7 (1.1 – 2.7) Low
    MCV 96.2 (81 - 99) Normal
    MCH 35.5 (28 - 33) High
    MCHC 36.9 (32 - 36) High
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    CHEMISTRY REPORT
    COAGULATION REPORT
    Albumin 35.5 (35 - 52) Normal
    Prothrombin Time Control 13.9
    BUN 6.2 (2.8 – 7.2) Normal
    Prothrombin Time Test 14.9
    Creatinine 82.7 (44 - 96) Normal
    INR 1.087
    SGPT/ALT 25.8 (0 - 34) Normal
    % Activity 80.5
    Electrolytes:
    APTT Control 31.8
    - Sodium 133.9 (135 - 148) Normal
    APTT Test 50.2
    - Potassium 3.7 (3.5 – 5.5) Normal
    IMMUNOLOGY REPORT
    - Chloride 101.9 (97 - 119) Normal
    ANA 1.11
    - Calcium 2.2 (2.1 – 2.7) Normal
    DsDNA 0.37
    Bilirubin
    - Total Bilirubin 201.6 (2 - 21) High
    - Direct Bilirubin 14.3 (0.1 – 3.4) High
    - Indirect Bilirubin 187.7 (1.9 – 18.6) High
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    HEMATOLOGY REPORT
    Bilirubin Panel was its abnormal
    Reticulocyte Count 1.6 (1.1 – 2.7) Normal
    state to trace the cause of its abnormality MCV 97.9 (81 - 99) Normal
    the physician requested for another MCH 35.7 (28 - 33) High
    laboratory tests: Hematology – Retic Count, MCHC 36.5 (32 - 36) High
    CHEMISTRY REPORT
    RBC Indices, Chemistry – Liver Enzyme SGOT/AST 26.5 (0 - 34) Normal
    Panel, Microscopy – Urinalysis, ALP 46.3 (38 – 126) Normal
    Immunology – Direct Coomb’s Test and SGPT/ALT 25.8 (0 - 34) Normal

    HBsAg.
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    CLINICAL MICROSCOPY REPORT: Urinalysis


    Macroscopy Based on the Laboratory Report –
    Color Light Amber
    -
    - Transparency Clear
    Day 2 the Direct Coomb’s Test shows that
    Chemistry
    - Leukocyte Negative
    the Platelet Concentration Transfusion was
    - Blood 3+ successful and the cause of its high level of
    - Nitrite Negative
    - Specific Gravity 1.010 Bilirubin Panel is not caused by Hepatitis B
    -
    -
    Urobilinogen
    Ketone
    Normal
    Negative
    Virus but in support to that the Liver
    - Protein Trace Enzyme test result was in its range. To
    - Bilirubin Negative
    - Ph 7.00 check if her platelet count was in range the
    - Sugar Negative
    Microscopy physician requested for another
    -
    -
    Pus Cells
    Epithelial Cell
    0-2/HPF
    Rare
    Hematology Report – Complete Blood
    IMMUNOLOGY REPORT Count with Platelet Count.
    Direct Coomb’s Test Negative
    HBsAg Non-Reactive
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

    Systemic Lupus Erythematosus may include cardiac


    involvement with pericarditis, tachycardia, or
    HEMATOLOGY REPORT
    ventricular enlargement; pleuritis with chest pain;
    Hemoglobin 92 (120 – 140) Low neuropsychiatric manifestations such as seizures,
    Hematocrit 0.27 (0.37 – 0.43) Low mild cognitive dysfunction, psychoses, or depression;
    White Blood Cells 13.2 (5 - 10) High
    or hematologic abnormalities such as anemia,
    - Neutrophil 0.74 (0.55 – 0.65) High
    - Lymphocyte 0.17 (0.25 – 0.35) Low leukopenia, thrombocytopenia, or lymphopenia. In
    - Eosinophil 0.00 (0.02 – 0.05) Low order for a clinical diagnosis of lupus to be made,
    - Monocyte 0.08 (0.02 – 0.05) High four of eleven specific criteria must be present: malar
    - Basophil 0.01 (0.0 – 0.06) Normal
    Platelet Count 8 (150 - 500) Low rash, discoid rash, photosensitivity, oral ulcers,
    arthritis, serositis, renal disorders, neurological
    disorders, hematologic disorders, immunologic
    disorders, and presence of antinuclear antibodies.
    THROMBOCYTOPENIC AUTOIMMUNE DISEASE OF A 20-YEAR OLD FEMALE
    IMMUNO-SEROLOGY BLOOD BANKING | GROUP 1

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