HB LSHBB WLDTRBT DHT LLQ
HB LSHBB WLDTRBT DHT LLQ
HB LSHBB WLDTRBT DHT LLQ
disorders
Disorders of sebaceous glands and
Rosacea
Fig 3
Perifollicular
Hyperkeratosis histology
Seborrhoea is a common feature between
patients with acne.
Fig 8
Hydrolytic enzymes released from the
activated complement antibodies complex
together with exoenzymes produced from
P acne cause rupture of follicular wall
Fig 9
Once the wall is damaged Various agents
(prostaglandin-like substance, amino acid,
short chain fatty acids) that are produced by
the inflammatory cells and P acne extrude to
the dermis causing more inflammation
Clinical features: (Acne and acne
related Disorders)
1. Acne Vulgaris:
Papules: (Less than 0.5 cm)
Comedones (Open Blackheads or closed
Whiteheads)
Open Comedones (Blackheads)
Fig 10 Fig 11
Open Comedones
Closed Comedones (Whitehead)
Fig 12 Fig 13
Closed Comedones
Inflammatory papules
Fig 14 Fig 15
Inflammatory
papules
Pustules :
Fig 16 Fig 17
Pustules
Nodule (more than 0.5 cm)
Fig 18 Fig 19
Nodule
Cystic acne: the cysts are usually
large 1-4cm
Fig 20
Fig 21
2. The nodules and cysts could be
associated with sinuses as in Acne inversa
Fig 27
7. Acne Agminata (Lupus Milliaris Disseminatus
Faciei)
Sanchez-Yus E, DejRb E, Simon P, Requenal A, Vazquez H.[ The histopathology of close and open Comedones of Favre-Racuchet
.disease]. Arch dermatol 1997 Dec. 133 (12) 1592
.Zugerman C. [ Chloracne, clinical manifestation and etiology]. Dermatol clin. 1990 jan. 8 (1) 209-13
.Khorsow Mehrany, Josedh M, Kist Roger H, Weenig, Patricia M, Witman. [ Acne Fulminana]. Inter. J. Dermatol 2005. 44 132
.Charles N, Ellis, Kent J, Krach. [ Uses and complications of isotretinoin therapy]. J Am Acad. Dermatol. 2001. 45: S1. 150-7
Bedlow A J. Otter M. Marsder R A. [ Axillary acne agminata ( lupus Miliaria Desseminatus Facies)]. Clin. Exp. Dermatolo 1998 May. 22
(3) 125-8
Ogunbiyi A, George A. [ Acne keloidalis in female: Case report and review of literature]. Nati. Med assoc. 2005 Aug. 97 (8) 1178
Alfred L, Knable Jr, C William Hanke, Rene Gonin. [ Prevalence of acne Keloidalis Nuchae in Football players ]. J Am Acad Dermatol
1997. 37. 570-4
Shenefelt PD. [ Using hypnosis to facilitate resolution of psychogenic excoriation in Acne Excoriee]. Am. J. Clin. Hypn. 2004 Jan. 46
(3) 239-45
Griffiths WA. [The red face-an overview and delineation of the MARSH syndrome]
Clin. Exp. Dermatol. 1999 Jan. 24(1):42-7
Thomas B Fitzpatreick, Richard Allen Johnson, Klaus Wolf, Dick Suurmond, [Disorders of Sebaceous and Apocrine glands]. Color Atlas
of Synopsis of Clinical Dermatology by McGraw-Hill. 2001 . Page 2-17
Diane Thiboutot, MD Hershey, Pennsylvania [Acne: 1991-2001] . J Am Acad Dermatol July 2002 Volume 47 Number 1 p109
to p117
Carolyn I. Jacob, MD,* Jeffrey S. Dover, MD, FRCPC, and Michael S. Kaminer, MD [Acne scarring: A classification system and review
of treatment options] J Am Acad Dermatol 2001; 45:109-17
Susan C. Taylor, Fran Cook-Bolden, Zakia Rahman, and Dina Strachan. [Acne vulgaris in skin of color] J Am Acad Dermatol 2002;
46:S98-106
Jerry K. L. Tan, Kirsten Vasey, Karen Y. Fung, [Beliefs and perceptions of patients with acne] J Am Acad Dermatol 2001;44:439-45
Lindsay Frazier, Walter C. Willett, Michelle D. Holmes. [High school dietary dairy intake and teenage acne]. J Am Acad A.
Dermatol 2005; 52:207-14
Brian B. Adams, MD, Viziam B. Chetty, MD, and Diya F. Mutasim, MD Cincinnati. [Periorbital comedones and their relationship to
pitch tar: A cross-sectional analysis and a review of the literature] J Am Acad Dermatol 2000;42:624-7
V. Goulden, G. I. Stables,W. J. Cunliffe. [Prevalence of facial acne in adults] J Am Acad Dermatol 1999; 41:577-80
Lowell A. Goldsmith, Jean L. Bolognia, Jeffrey P. Callen, Suephy C. Chen, Steven R. Feldman Henry W. Lim, Anne W. Lucky, Barbara
R. Reed Elaine C. Siegfried, Diane M. Thiboutot, onald G. Wheeland.[American Academy of Dermatology Consensus
Conference* on the Safe and Optimal Use of Isotretinoin: Summary and recommendations ] J Am Acad Dermatol 2004 june.
Volume 50 number 6
Marvi Iqbal, Michael S. Kolodney, [Acne fulminans with synovitis-acne-pustulosishyperostosis- osteitis (SAPHO) syndrome treated
.with infliximab] . J Am Acad Dermatol 2005;52:S118-20
Harold P. Lehmann, MD, PhD, Karen A. Robinson, MSc, John S. Andrews, MD,Victoria Holloway, MD, and Steven N. Goodman, MD,
MHS, PhD. [Acne therapy: A methodologic review]. J Am Acad Dermatol 2002;47:231-40
Harald Gollnick, MD, and William Cunliffe, Diane Berson, Brigitte Dreno, Andrew Finlay, James J. Leyden, Alan R. Shalita, Diane
Thiboutot. [Management of Acne A Report From a Global Alliance to Improve Outcomes in Acne]. J AM ACAD DERMATOL JULY
2003. VOLUME 49, NUMBER 1
Gary M. White. [Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris]. J Am Acad Dermatol
1998;39:S34-7
John Y. M. Koo, Jennifer H. Do, Chai Sue Lee. [Psychodermatology]. J AM ACAD DERMATOL NOVEMBER 2000. VOLUME 43,
NUMBER 5
Sharam S Yashar, Ali Moiin, .[ TREATMENT OF PSYCHODERMATOSES WITH SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS]. J
AM ACAD DERMATOL MARCH 2004. P 33
Wilkin J et al: Standard classification of rosacea: Report of the National Rosacea Societv Exoert Committee on the
classification and staging of rosacea J Am Acad Dermatol 46:584, 2002
Plewig C, Kligman A: Acne and Rosacea, 3rd ed. Berlin, Springer-Verlag, 2000, p 455
Wilkin J et al: Standard grading system for rosacea: Report of the National Rosacea Society Expert Commiittee on the
classification and staging of rosacea J An Acad Dermatol 5O:907,2004
Crawford C, Pelle M, James W: Rosacea: I. Etiology, pathogenesis, and subtype classification J Am Acad Dermatol 5L:327,2004
BogeEEPi et al: Surgical treatmen! of rhinophyma: A comparison of techniques Aesth Plast Surg 26:57, 2002