MS - K5 - Nutrition and Bone Health (Gizi)
MS - K5 - Nutrition and Bone Health (Gizi)
MS - K5 - Nutrition and Bone Health (Gizi)
Adequate nutrition is essential for the development and maintenance of the skeleton Bone disease complex etiologies development of disease by providing adequate amounts of nutrients
65 years 25% of the population by 2020 risk osteoporosis and (doubling or tripling) hip fracture
Calcium Metabolism
Calcium Homeostasis
Calcium Intake
Food sources are recommended first for supplying calcium needs because of the coingestion of other essensial nutrients Sources: Calcium from food Calcium from supplement Calcium from fortification food
Effect of supplement
High dose calcium supplement may reduce the absorption of nonheme iron and possibly zinc. Magnesium, and other divalent cations
Vitamin D
Vitamin D intake: adequate vit D intake is important excess need is avoided Sun light exposure for skin Calcium and vitamin D supplements are often given
Rickets
Phosphat intake
Calcium and Phosphat = 1:1 needed for mineralization High phosphorus bone loss Consumption 1000 mg to 1200 mg/day (females), 1200-1400 mg/day (male)
Protein intake
Anabolic effect High dietary proteinno effect Low dietary protein Low serum albuminlow IGF-1 and serum calcium vulnerable fracture 1 g/kg per day Animal protein rise urinary losses of calcium (acid) Plant proteinlittle effect (neutral or basic urin)
Magnesium intake
Little effect, but suggest adequate intakes of Mg improves BMD
Vitamin K intake
Osteocalcin needs vitamin K Vitamin K supplementation retard bone loss
Nutrition management
Adequate calcium intake Adequatevitamin D intake from food, supplement, and sun exposure Avoidance of excess phophorus A balance diet that procides adequate protein, energy, and micronutrients Exercise
Prevention
Three factors influenced (for women): diet, exercise, and estrogen Diet calcium from food (including fortified food), adequate intake of vitamin D either from sun exposure or foods or supplement Engaging in regular weight-bearing exercise Estrogen (before 50)
The end