6/29/24, 8:08 PM Numeracy Practice Quiz 1: PHAM01 - Applied Practice: Achieving Optimal Clinical Outcomes (2023/4 - Sunderland - ASUND

Outcomes (2023/4 - Sunderland - ASUND - SEM3)

Attempt Time Score

Attempt 2 120 minutes 13 out of 40

Attempt 1 120 minutes 17 out of 40

Submitted 23 Jun at 18:08


Question 1
1 / 1 pts

An asthma specialist nurse prescribes prednisolone 5mg tablets for an 11 year old patient with an acute asthma exacerbation. The patient weighs
36kg and requires a five-day course at a dose of 1mg/kg once daily.

How many prednisolone 5mg tablets will be required to provide treatment for the five-day course?

Correct!
35

35 (with margin: 0)
Send

Question 2
1 / 1 pts

A diabetic patient who weighs 60kg is prescribed a basal bolus insulin regimen. The fast acting insulin is started at a daily dose of 0.75 units/kg. The
daily dose will be split evenly and given before breakfast, lunch and dinner.

How many units of long-acting insulin should be administered before each meal?

Correct!
15

15 (with margin: 0)

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Question 3
1 / 1 pts

A nurse must prepare a 100mg/mL meropenem solution using one 500mg ampoule and water for injections. The displacement volume for
meropenem is 0.6mL/1g.

What volume in millilitres must be added to the ampoule in order to produce the required concentration?

Give your answer to ONE (1) decimal place.

Correct!

4.7

4.7 (with margin: 0)


Question 4
1 / 1 pts

An elderly gentleman is recovering from an infected hip prosthetic joint and is prescribed ciprofloxacin suspension. He has difficulty swallowing an
requires an oral preparation. You explain that you need to reconstitute the antibiotics and therefore he will need to return to the pharmacy for each
100mL bottle. The prescription is available below.

Given that each bottle has an expiry date of 7 days once reconstituted, how many bottles of ciprofloxacin 250mg/5mL suspension will be
supplied from the above prescription?

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Correct!

6 (with margin: 0)

Question 5
1 / 1 pts

A patient presents with a prescription for a titrating dose of gabapentin 100mg capsules and you are asked to issue the patient with a 28 day supply,
the prescription is written as follows:

“Gabapentin 100mg Capsules – Take ONE capsule DAILY, increasing to take ONE capsule TWICE DAILY after 2 days, then increasing to ONE
capsule THREE TIMES DAILY after 2 days and continue on this dose until next appointment.”

You have 52 capsules in stock in the pharmacy. How many capsules will be owed to the patient?

Correct!

26

26 (with margin: 0)

Question 6
0 / 1 pts

You are working in a specials lab producing a liquid formulation of DRUG-X, which is being used as part of a clinical trial.

A 10mL sample is taken from an initial 5%w/v stock solution and diluted to 100mL with water. A further 50mL is removed from this intermediary
solution and diluted to 100mL, with a further 1 in 5 dilution prepared thereafter to produce the final solution.

How many milligrams of DRUG-X is present in the final solution?

You Answered

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500

250 (with margin: 0)

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Question 7
1 / 1 pts

A 52-year-old woman has been prescribed oral vinorelbine 80mg/m2 once a week for stage 3 non-small cell lung cancer. Each treatment cycle of
vinorelbine takes three weeks. She has a body surface area of 1.45m2.

How many 30mg capsules should this patient be prescribed for the full treatment cycle?

Correct!
12

12 (with margin: 0)
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Question 8
1 / 1 pts

A GP rings the pharmacy asking for some advice, she has a patient who has been taking the maximum daily dose of tramadol and she wants to
convert him onto oral morphine as the pain is still not being controlled. The patient is currently taking 100mg of tramadol four times a day.

How many milligrams of oral morphine would provide the equivalent daily dose to the tramadol currently prescribed to the patient?

Extract from Online BNF

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Correct!
40

40 (with margin: 0)
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Question 9
1 / 1 pts

A patient (72.9kg) was prescribed MST 30mg tablets ONE to be taken TWICE a day for the treatment of pain associated with breast cancer. She
normally also takes 5mL of morphine 10mg/5mL oral solution four times a day, for breakthrough pain. The patient is stable and tolerates opioids well
but needs to be transferred from oral analgesia to a fentanyl patch.

What is the most appropriate Durogesic patch to prescribe?

Extract from Durogesic DTrans SPC

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Correct!
50

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50 (with margin: 0)

Question 10
1 / 1 pts

A randomised and double-blinded study compared vitamin C supplements vs placebo in 200 patients with recurrent UTIs. The event rate for
reporting UTIs was 0.32 in the treatment group and 0.42 in the placebo group.

What is the number needed to treat with vitamin C supplements to prevent one patient having a UTI?

ARC = the absolute risk of events in the control group

ART = the absolute risk of events in the treatment group
ARR (absolute risk reduction) = ARC – ART
NNT (number needed to treat) = 1 / ARR

Correct!

10

10 (with margin: 0)

Question 11
1 / 1 pts

You are advised that ranitidine 75mg/5mL solution contains ethanol at a concentration of 1.4%v/v. You wish to counsel patients about this.

You decide to explain the alcohol content in the equivalent amount in millilitres of beer (4% ABV) contained in a 10mL dose of the solution.

How many millilitres of 4% ABV beer would the alcohol content in a 10mL dose of ranitidine be equivalent to?

Give your answer in millilitres to ONE (1) decimal place.

ABV = mL of ethanol in 100mL of solution

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Correct!
3.5

3.5 (with margin: 0)


Question 12
1 / 1 pts

A 24-month-old child weighing 12.7kg has a urinary tract infection and is prescribed treatment with nitrofurantoin 25mg/5mL suspension at a dose of
3mg/kg/day in four divided doses.

What is the total in millilitres of nitrofurantoin 25mg/5mL suspension that should be given for each dose?

Give your answer to ONE (1) decimal place.

Correct!

1.9

1.9 (with margin: 0)

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Question 13
1 / 1 pts

Baby O is 15 weeks old and weighs 7.2kg. Baby O is admitted to hospital and diagnosed with bacterial meningitis. The consultant on duty
prescribes meropenem IV for 7 days. You have meropenem 500mg ampoules available in the dispensary.

Using the recommended dose in the SPC extract, how many ampoules will the pharmacy need to deliver to the paediatric ward in order to
complete the 7 day course?

Extract from SPC

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Correct!

21

21 (with margin: 0)

Question 14
1 / 1 pts
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6/29/24, 8:08 PM Numeracy Practice Quiz 1: PHAM01 - Applied Practice: Achieving Optimal Clinical Outcomes (2023/4 - Sunderland - ASUND - SEM3)

You are a foundation trainee working at a community pharmacy and one of your responsibilities is conducting a weekly CD balance check. The
balance of methadone 10mg/mL liquid in the CD register is stated as 60mL, however when you have calculated the actual volume in the CD cabinet
you have measured a volume of 56mL.

In the last week 20mL of methadone 10mg/mL liquid has been dispensed.

The SOP for controlled drugs states that you should calculate a percentage difference between the CD register balance and actual volume
measured in the CD cabinet using the following equation:

Difference (%) = (Difference in mL / Total amount dispensed since last balance check in mL) x 100

What is the percentage difference between the CD register balance and actual volume measured?

Correct!

20

20 (with margin: 0)

Question 15
1 / 1 pts

If a child who weighs 20kg is receiving 10mL twice a day of a 40% solution, what is the mg/kg daily dose?

Give your answer in mg/kg.

Correct!

400

400 (with margin: 0)

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Question 16
1 / 1 pts

A mother rushes her 13 month old son weighing 8kg to A&E with an alleged history of consumption of 8 ferrous sulphate 200mg tablets (each tablet
containing 65mg of ferrous iron). The tablets were prescribed to his mother for iron deficiency anaemia during her pregnancy. The child has
recurrent haematemesis and increasing irritability. The serum iron levels obtained were 320ug/dL (normal range 50-150ug/dL) and an IV infusion of
desferrioxamine is prescribed, at the following dose:

15mg/kg/hour for hours 1-4

10mg/kg/hour for hours 5-8

5mg/kg/hour for hours 9-12

After 7 hours, the patient’s serum iron levels are measured as 130ug/dL and the desferrioxamine is stopped.

How many milligrams of deferoxamine have been given to the patient over the course of the treatment?

Correct!
720

720 (with margin: 0)


Question 17
1 / 1 pts

A 55-year-old man is prescribed rifaximin 550mg twice a day for the management of chronic hepatic encephalopathy. He is unable to swallow
tablets and requires an oral suspension which is imported. Each 60mL bottle of the imported rifaximin oral suspension contains 100mg in 5mL and
costs £59.40. All the medicine in each original pack is used.

What is the exact total cost to provide 7 days of treatment? The liquid will be supplied in original packs.

Correct!

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415.8

415.8 (with margin: 0)


Question 18
1 / 1 pts

Bevacizumab is prescribed for metastatic colon cancer at a dose of 15mg/m2 given once, and the course is to be repeated every 3 weeks. The
maximum cumulative dose is 200mg/m2. You are reviewing a patient who is measured prior to treatment commencing and his height recorded as
179cm and weight as 68kg.

How many cycles could the patient be given safely before reaching cumulative dose?

Round your answer to the nearest number of cycles.

Correct!
13

13 (with margin: 0)

Question 19
1 / 1 pts

Recently published data highlights the prevalence of patients over 18 years old with asthma is 1 in 20 and the prevalence of patients over 18 years
old with COPD is 1 in 30.

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6/29/24, 8:08 PM Numeracy Practice Quiz 1: PHAM01 - Applied Practice: Achieving Optimal Clinical Outcomes (2023/4 - Sunderland - ASUND - SEM3)

Your surgery has 5000 patients currently enrolled. How many more patients aged over 18 would you expect to have asthma over COPD?
Round your answer to the nearest whole number.

Correct!
83

83 (with margin: 0)

Question 20
1 / 1 pts

A prescriber asks you to prepare 80g of a 1 in 4 dilution of clobetasol 0.05% ointment. You use emulsifying ointment as the diluent. How much
clobetasol 0.05% ointment is required to make this preparation?

Give your answer in grams.

Correct!
20

20 (with margin: 0)

Question 21
1 / 1 pts

What quantity of 78% stock solution is required to make 250mL of 3% solution for application to the skin?

Give your answer in millilitres.

Give your answer to TWO (2) decimal places.

Correct!
9.62

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9.62 (with margin: 0)


Question 22
1 / 1 pts

A patient is supplied with 100mL of a mouthwash from their dentist and told to dilute it 1 in 4 with water prior to using. After diluting, the mouthwash
concentration is 5%v/v.

What is the strength of the original mouthwash in %v/v?

Correct!
20

20 (with margin: 0)

Question 23
1 / 1 pts

How many millilitres of a 20% v/v solution should you use to make 100mL of a product such that 10mL diluted to 50mL will give a 0.2% solution?

Give your answer in millilitres.

Correct!
5

5 (with margin: 0)

Question 24
1 / 1 pts

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6/29/24, 8:08 PM Numeracy Practice Quiz 1: PHAM01 - Applied Practice: Achieving Optimal Clinical Outcomes (2023/4 - Sunderland - ASUND - SEM3)

A patient with severe pulmonary oedema is prescribed IV furosemide 10mg/mL at a dose of 120mg. The maximum recommended infusion rate is
4mg/minute.

If the infusion is started at the maximum rate, how long will it take for the prescribed dose to be administered?

Give your answer in minutes.

Correct!

30

30 (with margin: 0)

Question 25
1 / 1 pts

A palliative patient is being cared for at home by the Macmillan nursing team. She is prescribed oxycodone 120mg to be given subcutaneously over
24 hours at home using a McKinley syringe driver. Oxycodone 30mg/mL 1mL ampoules are prescribed and the final syringe is made up to a final
volume of 17mL with sodium chloride 0.9%.

What is the correct infusion rate in mL/hour that the syringe driver should be set at?

Give your answer in mL/hour and to ONE (1) decimal place.

Correct!
0.7

0.7 (with margin: 0)


Question 26
1 / 1 pts
A patient has been recently diagnosed with type 2 diabetes and is currently undergoing a trial of lifestyle interventions. Her BMI is currently 32kg/m2
and she has a height of 158cm. How many kilograms would the patient need to lose to reach a ‘healthy’ BMI of 25mg/m2? Give your answer

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to the nearest whole number.

Correct!
17

17 (with margin: 0)

Question 27
1 / 1 pts

A 37-year-old man requires insulin for type 2 diabetes. He is prescribed Toujeo (insulin glargine 300 units/mL) 38 units in the evening as his basal
insulin. His GP prescribes one box of five 1.5mL injection pens.

How many full days will this prescription last?

Assume a single injection from the pen device will be used to provide each dose.

Correct!
55

55 (with margin: 0)

Question 28
1 / 1 pts

You are working as a pharmacist for the CCG and have identified potential cost effective branded generic switches in oral contraceptive drugs.

Yasmin® – 63 tablets £14.70

Lucette® – 63 tablets £6.38

Across the CCG, there are 180 patients prescribed Yasmin®.

What would be the cost savings per 63 tablets if all patients were switched from Yasmin® to Lucette®.

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Give your answer to the nearest pound (£).

Correct!

1,498

1,498 (with margin: 0)


Question 29
1 / 1 pts

An elderly patient is admitted to hospital with signs of phenytoin toxicity. He is currently prescribed phenytoin and the junior doctor on duty orders a
plasma phenytoin level. The measured phenytoin level comes back within range as 18mg/L, however the patient also has low albumin, which is
recorded as 24g/L.

Calculate the corrected phenytoin concentration for the patient.

Give your answer to ONE (1) decimal place.

Correct!
29.3

29.3 (with margin: 0)


Question 30
1 / 1 pts
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6/29/24, 8:08 PM Numeracy Practice Quiz 1: PHAM01 - Applied Practice: Achieving Optimal Clinical Outcomes (2023/4 - Sunderland - ASUND - SEM3)

A child (age 12 years) is prescribed Peptac Suspension, 5mL four times a day. Peptac Suspension contains 1.9mmol of Na+/5mL.

The recommended daily allowance (RDA) of salt for a 12 year old is 3.8g (1.5g of sodium) per day.

The atomic mass of sodium is 23.

What percentage of this child’s recommended daily salt allowance is contained in the total daily dose of Peptac Suspension?

Round your answer to the nearest whole number.

Correct!
12

12 (with margin: 0)

Question 31
1 / 1 pts

A child has been recently diagnosed with Type I Diabetes. They are prescribed lidocaine 4%w/w cream to numb the surface of the skin prior to
insulin injections. The instructions state to apply 2.5cm (120mg of lidocaine) of cream to the area and then cover with an occlusive dressing.

If the patient injects insulin twice a day, how many full days will a 30g tube last?

Correct!
5

5 (with margin: 0)

Question 32
1 / 1 pts

A patient with vitamin D deficiency is advised to take 60,000 units of ergocalciferol weekly for 12 weeks. What is the total dose of ergocalciferol
that the patient will receive during the full treatment course?

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Give your answer in milligrams

Ergocalciferol conversion: 1 unit = 25 nanograms

Correct!
18

18 (with margin: 0)

Question 33
1 / 1 pts

An elderly gentleman is recovering from an infected knee prosthetic joint and is prescribed ciprofloxacin suspension 500mg twice daily. He has
difficulty swallowing and requires an oral preparation.

Ciprofloxacin 250mg/5mL suspension is available in bottles of 100mL and lasts 14 days once reconstituted. The product is being dispensed in
original bottles and the patient has a review appointment at the hospital in 22 days.

How many bottles of ciprofloxacin 250mg/5mL suspension should be dispensed in order that it lasts until the review appointment?

Correct!
5

5 (with margin: 0)

Question 34
1 / 1 pts
A 7-year-old patient who weighs 24.5kg is prescribed levetiracetam at a dose of 15mg/kg twice a day. To aid compliance, each dose is rounded to
one decimal place. How many millilitres of levetiracetam 100mg/mL suspension should be prescribed for each day? Give your answer to
ONE (1) decimal place.
Correct!
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7.4

7.4 (with margin: 0)


Question 35
1 / 1 pts

A 61 year old male patient has renal impairment. He has skeletal metastases as a result of multiple myeloma and his oncologist decides to
prescribe sodium clodronate at a dose of 1.6g daily. You decide to check the patient's renal function: his serum creatinine is found to be
132micromol/litre. His weight is 62kg.

Calculate an appropriate daily dose of sodium clodronate for Mr J.

Give your answer in milligrams.

Constant: 1.04 (women); 1.23 (men)

Extract from Online BNF

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Correct!
1,200

1,200 (with margin: 0)


Question 36
0 / 1 pts

A nurse must prepare a 10mg/mL solution of morphine hydrochloride. She has a 20mg vial of morphine hydrochloride. The displacement volume for
morphine hydrochloride is 0.08mL/5mg.

What volume in millilitres must be added to the vial in order to produce the required concentration? Give your answer to TWO (2)
decimal places.

You Answered
1.84

1.68 (with margin: 0)

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
Question 37
1 / 1 pts

You are working in the pharmacy technical services department making total parental nutrition (TPN) for the neonatal unit.

You are asked to add a total of 20mmol of sodium ions to a 500ml batch of feed. How many mL of sodium chloride injection 5% do you
need to add?

Give your answer to one decimal place.

(Atomic weight of sodium = 23, chloride = 35.5)

Correct!

23.4

23.4 (with margin: 0)


Question 38
1 / 1 pts
A patient, who weighs 61.6kg, has been prescribed azathioprine for the treatment of Crohn’s disease at a dose of 2.5mg/kg daily in 2 divided doses.
He is given a prescription for an 8-week supply and has been informed to attend for appropriate monitoring within this time. How many 25mg
tablets of azathioprine tablets will the patient require for 28 days treatment?
Correct!

168

168 (with margin: 0)


Question 39
1 / 1 pts

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A paediatrician prescribes Nutramigen Lipil 1® infant milk for a 6-week-old infant weighing 4.1kg to manage a cow’s milk protein allergy. Based on
the instructions for preparation provided by the manufacturer, how many 400g cans are required for a 14-day supply, based on the baby
taking the maximum number of feeds recommended?

The Nutramigen® product literature is available below:

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Correct!

4 (with margin: 0)

Question 40
1 / 1 pts

A patient is to receive a 0.8g dose of a drug at a rate of 80mL/hr. The reconstituted solution is mixed with sodium chloride 0.9% to produce a
concentration of 5mg/mL.

Calculate the minimum time in minutes that the dose can be given over.

Correct!
120

120 (with margin: 0)

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