Worksheet 1 - Endocrine - 2022 (11th Ed)

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Human Anatomy & Physiology

Endocrine Topics: Biochemistry, Secretion, & Transport of Hormones


Name_______________________________________________ Section_____________ Date__________________

Based upon Human Anatomy & Physiology, 11th edition, Marieb & Hoehn, Pearson, 2019
Updated - December 28, 2022

Enter the responses on a Scantron Answer Sheet (if used for submission in the class room setting).

1. The two major control systems of the body are the: (602)
A. Autocrine & the Endocrine
B. Autocrine & the Nervous
C. Autocrine & the Paracrine.
D. Endocrine & the Nervous
E. Endocrine & the Paracrine
2. The more rapid of the two major control systems of the body, usually responding in milliseconds, is the: (602)
A. Autocrine
B. Endocrine
C. Nervous
D. Paracrine
E. Neither of the two major control systems control that fast
3. The chemicals released by the nervous system are called: (396, 413-415)
A. Autocrines
B. Hormones
C. Neurotransmitters
D. Paracrines
E. None of the above
4. Chemicals that exert their effects on the same cells that secrete them are called: (603)
A. Autocrines
B. Hormones
C. Neurotransmitters
D. Paracrines
E. None of the above
5. Chemicals that exert their effects locally, affecting cells other than those that released them, are called: (603)
A. Autocrines
B. Hormones
C. Neurotransmitters
D. Paracrines
E. None of the above

Using the key: A. Lipid-soluble


B. Water-soluble
Indicate the solubility of each of the following chemicals. (603)
6. A B Peptides
7. A B Steroids
8. A B Thyroid hormone

9. Steroids are made from the molecule (603)


A. Cholesterol
B. Ethanol
C. Glucose
D. Glycerol
E. Sucrose
Using the key: A. Amino-acid based hormones
B. Eicosanoids
C. Steroids or Steroid hormones
Indicate the class into which each of the following chemicals falls. (603, 623, 626)
10. A B C Cortisol
11. A B C Epinephrine
12. A B C Leukotrienes
13. A B C Prostaglandins

14. T F Fat-soluble hormones, e.g. thyroid hormone, can directly enter the plasma membrane to activate target cells. (603)

15. Second-messenger signaling systems are needed for (604)


A. Fat-soluble hormones
B. Thyroid hormones
C. Water-soluble hormones
16. G-proteins are used in connection with (604)
A. Fat-soluble hormones
B. Thyroid hormones
C. Water-soluble hormones
17. Intracellular receptors and Direct gene activation are associated with (606)
A. Fat-soluble hormones
B. Thyroid hormones
C. Water-soluble hormones
D. All of the above
E. A and B only
18. What types of stimuli control the secretion of many, most, hormones? (607)
A. Hormonal
B. Humoral
C. Neural
D. All of the above
E. A and B only

19. T F The half-life of a chemical is the time it takes for the concentration to be reduced to one half if its initial value. (608)

20. The situation in which one hormone cannot exert its full effects without another hormone being present is called: (609)
A. Antagonism
B. Permissiveness
C. Synergism
21. The situation that occurs when more than one hormone produces the same effects at the target cell and their combined effects are
amplified. (609)
A. Antagonism
B. Permissiveness
C. Synergism
22. The situation in which one hormone opposes the action of another hormone. (609)
A. Antagonism
B. Permissiveness
C. Synergism
23. Peptide hormones (such as ACTH) are often synthesized on ribosomes as large precursor molecules called (616)
A. DNA
B. mRNA
C. Preprohormones
D. Prohormones
E. tRNA
24. Thyroid hormone contains the special (trace) element (617)
A. Cobalt
B. Chromium
C. Iodine
D. Iron
E. Zinc
25. Thyroid hormone actually includes two molecules (618)
A. Diiodotyrosine and Monoiodotyrosine
B. Diiodotyrosine and Triiodothyronine
C. Monoiodotyrosine and Thyroxine
D. Monoiodotyrosine and Triiodothyronine
E. Thyroxine and Triiodothyronine

Thyroglobulin (619)
26. T F has tyrosine as one of its important amino acids
27. T F is made in the thyroid follicle cells

28. Tyrosine (619)


A. Can bind only 1 iodine atom
B. Always binds 2 iodine atoms
C. Binds either 1 or 2 iodine atoms
D. Doesn’t bind iodine atoms
29. The thyroid gland releases (620)
A. About equal amounts of T3 and T4
B. More T3 than T4
C. More T4 than T3
30. The activity level of T3 and T4 is (620)
A. T3 and T4 are about equally active
B. T3 is less active than T4
C. T3 is more active than T4
31. Produced by the inner portion of the adrenal cortex (623)
A. Cholesterol
B. Cortisol
C. Epinephrine
D. Norepinephrine
32. Cells of the adrenal medulla are modified forms of what part of the sympathetic nervous system? (627)
A. First-order sensory neurons
B. Lower motor neurons
C. Postganglionic neurons
D. Preganglionic neurons
E. Upper motor neurons

Using the key: A. Adrenal medulla cells


B. Sympathetic postganglionic neurons
C. Both A and B
D. Neither A nor B
Answer the following questions.
33. A B C D Lack axons (542)
34. A B C D Produce epinephrine (542)
35. A B C D Primarily produce norepinephrine (421, 535)
36. A B C D Produce catecholamines (423, 627)
37. A B C D Product is released into a synapse
38. A B C D Release product into the blood stream
39. A B C D Product functions as a neurotransmitter
40. A B C D Product functions as a hormone
41. A B C D Triggered by preganglionic sympathetic fibers (540)

42. The smallest peptide is made from a chain of how many amino acids? (48)
A. 2
B. 3
C. 4
D. 5
E. None of the above
43. A polypeptide is a chain of at least how many amino acids? (48)
A. 5
B. 10
C. 25
D. 50
E. 100
44. A protein is defined as a chain of more than how many amino acids? (48)
A. 10
B. 25
C. 50
D. 100
E. 500
45. Proteins are made from chains of amino acids that can contain more than how many amino acids? (48)
A. 50
B. 200
C. 500
D. 3,000
E. 10,000
46. The biogenic amines called the catecholamines are derived from the amino acid (423)
A. Alanine
B. Arginine
C. Asparagine
D. Glycine
E. Tyrosine
47. Which of the following hormones is not a catecholamine? (423)
A. Dopamine
B. Epinephrine
C. Norepinephrine
D. Serotonin
48. Insulin is what kind of a molecule? (630)
A. Amine
B. Amino acid
C. Peptide
D. Protein
E. Saccharide
49. Insulin is made in what organ? (630)
A. Duodenum (small intestine)
B. Liver
C. Mouth
D. Pancreas
E. Stomach
50. Insulin is made in what cells? (630)
A. á-cells
B. â-cells
C. ã-cells
D. ä-cells
E. F cells

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