NLC Physio JULY 2023 Mcqs

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NLC PHYSIOLOGY TEST MCQS

In a man weighing 70 KG Total body water would be


a. 20-30 L
b. 30-40 l
c. 40-45 L
d. 50-60 L

Glucose is absorbed in intestine by?


a) Primary active transport
b) Facilitated diffusion
c) Simple diffusion
d) Secondary active transport

SGLT - 1 is situated on
a. RBC
b. Intestine
c. Brain
d. Liver

Process of exchange between lung capillaries and alveoli is


a. Active transport
b. Passive diffusion
c. Filtration
d. Facilitated diffusion

Which is correct about function of Antiporter?


a. Both molecules go inside
b. One molecule goes in and other goes out
c. Both molecules go out
d. One molecule goes in and two exit out
The amount of fluid absorbed in the intestine in a day is around

a. 5L
b. 11L
c. 1L
d. 8L

Surfactant is made up of which of the following:


a. Degradable products
b. Mucoprotein
c. Fibrinogen
d. Phospholipid

Which of the following secretes surfactant:


a. Type II pneumocytes
b. Type I pneumocytes
c. Goblet cells
d. Paneth cells

Ventilation-perfusion ratio is max at apex of lung due to:


a. Blood flow is increased considerably more than ventilation
b. Blood flow is decreased considerably more than ventilation
c. Base of lung has high ventilation in relation to blood flow
d. Direct connection with trachea

Vital capacity is:


a. TV+RV
b. IRV+ERV
c. TV+IRV+ERV
d. TV+IRV

FRC is:
a. Dead space volume
b. Volume of air present after normal expiration
c. Volume of air present after forceful expiration
d. Residual volume
Normal functional residual capacity is:
a. 2.3L
b. 1.3L
c. 2.9L
d. 4.5L

Lung diffusion capacity is measured with:


a. CO2
b. CO
c. O2
d. H2

Tidal volume is:


a. Total vital capacity + RV
b. Functional residual capacity - RV
c. TLC-RV
d. Inspiratory capacity – inspiratory reserve volume

High affinity of HbF with O2 due to:


a. Decrease binding with 2,3 DPG
b. Decrease concentration of Hb
c. Increase in the pH
d. Bohr effect

An increase in which of the following parameters will shift the O2 dissociation curve to the left:
a. Temperature
b. Partial pressure of CO2
c. 2,3 DPG concentration
d. O2 affinity of Hb

Decreased O2 affinity of Hb in blood with decreased pH:


a. Haldane effect
b. Double Haldane effect
c. Bohr effect
d. Double Bohr effect

CO2 is transported in blood mainly as:


a. Free CO2
b. Bicarbonate
c. Carbamino compound
d. Plasma protein

Pacemaker of respiration lies at:


a. DRG
b. Pneumotaxiccentre
c. Aponeusticcentre
d. Pre botzinger complex

Central chemoreceptors are most sensitive to:


a. Increase in CO2 tension
b. Decrease in CO2 tension
c. Low O2 tension
d. Increase in H+

4. Peripheral & central chemoreceptors respond to?


a. Increased arterial pH
b. Increased arterial O2
c. Increased arterial CO2
d. Decreased arterial CO2

Physiological dead space is:


a. 150 ml
b. 200 ml
c. 250 ml
d. 100 ml

6. Hypoxia without cyanosis is:


a. Stagnant hypoxia
b. Hypoxic hypoxia
c. Anemic hypoxia
d. All of the above

In which of the following area of the lung the ventilation perfusion ratio is maximum:
a. Apex of lung
b. Base of lung
c. Equal in all areas
d. Right posterior lobe
Muscle of expiration:
a. Diaphragm
b. Internal intercostals
c. External intercostals
d. Biceps

5. Adequate oxygen delivery at cellular level occurs in which type of hypoxia?


a. Hypoxic
b. Anaemic
c. Stagnant
d. Histotoxic

Which of the following has maximum smooth muscle as compared to wall thickness?
a. Respiratory bronchiole
b. Alveoli
c. Terminal Bronchiole
d. Alveolar ducts

During the cardiac cycle, the opening of the aortic valve


takes place at the
a) End of isovolumterc relaxation.
b) Begining of isovolumetric relaxation.
c) Begining of isovolumetric contraction.
d) End of isovolumetric contraction.

First heart sound and second heart sound are respectively


due to
a) Opening of semilunar and atrioventricular valves
b) Closure of semilunar and atrioventricular valves
c) Closure of atrioventricular and semilunar valves
d) Opening of atrioventricular and semilunar valves
‘c’ wave in JVP is seen in
a) Iso-volumetric contraction
b) Slow filling at end of diastole
c) End of systole
d) Start of diastole

The SA Node acts as the pacemaker of the heart because,


it
a) Generates impulse spontaneously
b) Has rich sympathetic innervation
c) Generates impulses at highest rate
d) Has poor cholinergic innervation

In which of the following the conduction velocity is least?


a) AV node
b) Ventricles
c) Bundle of His
d) Purkinje fibers

The AV nodal delay is __(seconds)o


a) 0.2
b) 0.1
c) 0.5
d) 0.01

Which part of the ECG corresponds to ventricular


repolarization?
a) The P wave
b) The QRS duration
c) The T wave
d) The U Wave

If radius of a vessel is doubled, then the blood flow is increased by:


a. 8 times
b. 16 times
c. 32 times
d. 256 times

Starling’s principle is:


a. Muscle fiber length does not affect contraction
b. Contraction is proportional to blood flow
c. Within physiological limits, the force of contraction is proportional to initial length of
cardiac muscle fiber
d. Energy of contraction is proportional to afterload

Maximum peripheral resistance is at:


a Arterioles
b Capillaries
c Small arteries
d Aorta

Vagal stimulation causes increase in:


a) Heart rate
b) Diastole duration
c) Cardiac output (CO)
d) Force of contraction

QRS complex indicates which of the following:


a. Atrial repolarization
b. Ventricular repolarization
c. Atrial depolarization
d. Ventricular depolarization

Atrial repolarization normally occurs during the:


a. P wave
b. QRS complex
c. ST segment
d. T wave
Mean arterial pressure is equal to:
a. Systolic + diastolic pressure/2
b. Diastolic + 1/3rd Pulse pressure
c. Systolic + diastolic pressure/3
d. Systolic + 1/4th diastolic pressure

Pressure on carotid sinus leads to:


a. Tachycardia
b. Increased blood pressure
c. Reflex bradycardia
d. Bain bridge reflex

86. Best Autoregulation is seen in


a. Liver
b. Muscles
c. Kidneys
d. Brain

Stimulation of baroreceptors lead to


a. Increase in BP & HR
b. Decrease in BP & HR
c. Increased intracranial tension
d. All of the above

Pulmonary wedge pressure corresponds to which of the following:


(a) Right ventricular pressure
(b) Left ventricular pressure
(c) Left atrial pressure
(d) Right atrial pressure

What is the effect of sympathetic stimulation on GFR?


a) increase GFR with afferent arteriolar dilation
b) increase GFR with efferent arteriolar dilation
c) decrease GFR with afferent arteriolar constriction
d) decrease GFR with Efferent arteriolar constriction
In a patient, urine flow rate is 10 ml-I min; plasma inulin
is 2 mg/mL; and urine inulin is 25 mg/ml-. Which of the
following is true assuming GFR to be normal?
a) Inulin clearance = GFR
b) Inulin clearance > GFR
c) Inulin clearance < GFR
d) GFR cannot be calculated

Potassium is maximally absorbed in


a) PCT
b) DCT
c) Collecting duct
d) Loop of henle

A dehydrated patient is excreting hypertonic urine.


Absorption of water in which part of the nephron causes
this?
a) Collecting duct
b) PCT
c) Ascending loop
d) Descending loop

A patient with diabetes insipidus is prescribed vasopressin.


This drug has its maximum effect on which part of the
renal tubule?
a) Proximal tubule
b) Distal tubule
c) Loop of henle
d) Collecting duct

The most important neurotransmitter of reward pathway is


a) Dopamine
b) Serotonin
c) Noradrenaline
d) Acetylcholine
Fast vibration sense is mediated by
a) Merkel's disc
b) Meissner's corpuscle
c) Pacinian corpuscles
d) Ruffini's end organ

A patient comes to you for his annual health checkup, He


lost his vision due to an accident a few years ago, He now
experiences the world through touch. Which of the
following Brodmann's areas processes this tactile
stimulation?
a) 3,1,2
b) 4,6
c) 44,45
d) 41,42

Somatosensory area has the largest representation for


a) Lips
b) Hand
c) Thumb
d) Back

A man was rushed to the casualty after getting stabbed in


the back with a knife. On MRI, a complete transection of
one side of the spinal cord is suspected, Which of the
following is likely to be seen in this patient?
a) Pain and temperature loss on the opposite side
b) Fine touch lost on the opposite side
c) Pain and temperature lost on the same side
d) Only pain lost on the same side

Itch is carried by
a) Dorsal column
b) Spinocerebellar tract
c) Anterolateral system
d) Corticospinal tract
Which form of vitamin A combines with opsin to make
rhodopsin in DARK?
a) All trans retinaldehyde
b) 11-cis -retinaldehyde
c) All trans retinol
d) 11-cis- retinol

Which is the first-order neuron in the optic pathway?


a) Rods and cones
b) Ganglion cells
c) Cells in lateral geniculate body
d) Bipolar cells

Umami taste is evoked by


a) Glucose
b) Quinine
c) Glutamate
d) Sodium chloride

A lady presents with vascular injury to the inferior


frontal gyrus. Which functional area is likely to be
affected?
a) Motor speech area
b) Wernicke's area
c) Auditory area
d) Visual area

Most of the C02 transported in the arterial blood is in the form of


HCO3-
Attached to haemoglobin
Carbamino compounds
Carbonic acid (H2CO3)

The oxygen-haemoglobin dissociation curve is sigmoid shape because


Binding of one 02 molecule increases the affinity of binding of subsequent O2 molecules
Binding of one 02 molecule decreases the affinity of binding of subsequent O2 molecules
Bohr effect
Haldane effect

Bohr effect
Facilitates O2 release
Facilitates CO2 transport
Facilitates chloride transport
None

Haldane effect is
Binding of O2 to Hb favours release of CO2
Binding of CO2 to Hb favours release of O2
HCO3- leaving RBC in exchange for Cl-
None of the above

A nurse in the pulmonology clinic administered a test using the following instrument in a patient
Which of the following parameters cannot be measured?

Tidal volume
Residual volume
Vital capacity
Inspiratory reserve capacity

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