Model Questions Biology For Engineers
Model Questions Biology For Engineers
Model Questions Biology For Engineers
Set-2
1. Bacteria Cannot Be Seen With the Naked Eyes, but These Can Be Seen With the Help of
a Microscope. If You Have to Carry a Sample from Your Home to Your Biology
Laboratory to Demonstrate the Presence of Microbes Under a Microscope, Which Sample
Would You Carry and Why?
Ans. A sample, Curd, can be used for the study of microbes. Numerous lactic acid bacteria
(LAB) or Lactobacillus are present in Curd. Acids are produced by these bacteria that coagulate
and digest milk proteins.
In the research laboratory, a tiny low drop of curd is carried because it contains multitudes of
bacteria, which might be easily observed under a microscope which are of varied shapes and
sizes.
2. Give Examples to Prove That Microbes Release Gases During Metabolism.
Ans. For the release of gases during metabolism, the examples are:
(a) A puffed appearance is seen in dough which is used for making idli and dosa . This is Due to
the action of bacteria; carbon dioxide is released. This CO₂ released from the dough gets caught
within the dough, hence giving it a puffed appearance.
(b) During wastewater treatment, the digestion of sludge produces a bacteria which is a mixture
of gases such as methane, hydrogen sulphide and carbon dioxide.
3. In Which Food Would You Find Lactic Acid Bacteria? Mention Some of Their Useful
Applications.
Ans.Lactic acid bacteria is present in curd.
Their useful applications are as follows:
(i) Formation of milk into curd is produced by this bacterium.
(ii) Multiplication of the bacterium increases its number, which converts the milk into curd.
(iii) The content of vitamin B12 increases in the curd.
(iv) Presence of lactic acid bacteria in the stomach keeps a check on the disease- causing micro-
organisms.
4. Name Some Traditional Indian Foods Made of Wheat, Rice and Bengal Gram (or Their
Products) Which Involve Use of Microbes.
Ans.
(i) In the making dosa and idli, rice powder is fermented by bacteria and for creating bread (from
wheat), yeast (Saccharomyces cerevisiae) is employed.
(ii) Gutta (made from black gram) also uses bacteria.
(iii) Microbes are accustomed to ferment fish, soya bean and bamboo shoots to create foods.
5. In Which Way Have Microbes Played a Major Role in Controlling Diseases Caused by
Harmful Bacteria?
Ans.
(i) Several microorganisms are used for preparing medicines. In order to kill other disease-
causing microorganisms antibiotics were developed which are produced by certain
microorganisms.
(ii) Medicines are usually obtained from bacteria and fungi. Either they get killed or the growth
gets stopped by disease-causing microorganisms.
(iii) For the treatment of life-threatening diseases such as plague, whooping cough (kali khansi),
diphtheria (galghotu) and leprosy (kusht rog) and for many other common infections different
antibiotics were used which are Streptomycin, tetracycline, and penicillin are common ones .
(iv) Growth of Staphylococci bacteria in the body was checked by chemical penicillin produced
by Penicillium notatum, a fungus.
(v) Bacteria were destroyed by weakening their cell walls by antibiotics. Due to this weakening,
certain immune cells such as the white blood cells enter the bacterial cell and cause cell lysis.
The process of destroying cells such as blood cells and bacteria is cell lysis.
6. Name Any Two Species of Fungus, Which are Used in the Production of Antibiotics.
Ans.
Antibiotics are drugs produced by certain microorganisms to fight disease-causing
microorganisms. These medications are frequently derived from microbes and fungus.
The following fungi are used in the production of antibiotics.
Removal of large and small particles from the sewage It includes the biological digestion
through filtration and sedimentation by physical means. of organic matter by microbes.
9. Do You Think Microbes Can Also Be Used as a Source of Energy? If Yes, How?
Ans.Yes, microbes can be used as an energy source. Bacteria like Methane bacterium are
employed for the generation of gobar gas or biogas.
(i) In a biogas plant, the generation of biogas is an anaerobic process which consists of a concrete
tank (10-15 feet deep) with sufficient outlets and inlets.
(ii) Slurry is formed by the mixture of dung and water and is further thrown into the tank. The
digester of the tank contains numerous anaerobic methane-producing bacteria, which produce
biogas from the slurry.
(iii) Biogas can be used as a source of energy after removal through the pipe, while the spent
slurry is removed from the outlet and is used as a fertilizer.
10. Microbes Can Be Used to Decrease the Use of Chemical Fertilizers and Pesticides.
Explain How This Can Be Accomplished.
Ans.Organisms that enrich the nutrient quality of the soil are the microbes which can be
employed as acterium zers .Bacteria, fungi and cyanobacteria are the main sources of
acterium zers . By this, fertility of the soil is increased in many ways
(i) Nodules on the roots of leguminous plants (a symbiotic association) that is formed by
Rhizobium fixes the atmospheric nitrogen into organic form, which is used by the plant as a
nutrient.
(ii) Fixing atmospheric nitrogen by Azospirillum and Azotobacter , while living freely, and
enhancing the nitrogen content of the soil.
(iii) Symbiotic association is formed by the many members of the genus Glomus (fungi) with
vascular host plants known as mycorrhiza that:
a. Helps within the absorption of phosphorus from soil and pass it to the plant.
b. Resistance to root-borne pathogens are developed within the plants.
c. Overall increase in plant growth and development can be done by increasing their
tolerance to salinity and drought.
(iv) Cyanobacteria autotrophic microbes, e.g., Anabaena, Nostoc, Oscillatoria can fix
atmospheric nitrogen, in aquatic and terrestrial environments and also add organic matter to the
soil and increase its fertility.
11. Three Water Samples Namely River Water, Untreated Sewage Water and Secondary
Effluent Discharged from a Sewage Treatment Plant Were Subjected To BOD Test. The
Samples Were Labelled A, B and C; but the Laboratory Attendant Did Not Note Which
Was Which. The BOD Values of the Three Samples A, B and C Were Recorded as 20
mg/L, 8 mg/L and 400 mg/L, Respectively. Which Sample of the Water Is Most Polluted?
Can You Assign the Correct Label to Each Assuming the River Water is Relatively Clean?
Ans.The amount of oxygen required by micro-organisms to decompose the waste present in the
water supply is determined using the Biological Oxygen Demand (BOD) method. When the
water supply contains high levels of organic wastes, the number of decomposing bacteria also
increases, leading to a higher BOD value. Consequently, water supplies that are more polluted
tend to have higher BOD values. Sample C, with a BOD value of 400 mg/L, is the most polluted
among the three samples. The discharge of secondary effluent from a sewage treatment plant is
more polluted than river water, which explains why sample A has a higher BOD value of 20
mg/L compared to sample B, which has a BOD value of 8 mg/L and is sourced from a river.
Hence, the correct label for each samples are:
14. Arrange the Following in the Decreasing Order (most Important First) of Their
Importance, for the Welfare of Human Society. Give Reasons for Your Answer.
Biogas, Citric acid, Penicillin and Curd
Ans.Penicillin > Biogas > Curd > Citric acid
Penicillin is the most crucial product for human welfare in society. It is an antibiotic that
is used to treat a variety of bacterial infections.
Biogas is the second most important product. It is an environmentally friendly form of
energy as it is non-polluting decent fuel that is produced as a byproduct of sewage
treatment.
Curd, a food item produced by the action of lactobacillus bacteria on milk, it has
excellent nutrient value, providing vitamin-B12 and replaces unfavourable bacteria of
the stomach.
Citric acid, which is acteriu as a food preservative, is the next most important product.
2. If a marine fish is placed in a freshwater aquarium, will the fish be able to survive? Why
or why not?
Ans: If a marine fish is placed in a freshwater aquarium, then its possibilities of survival will
diminish. This is often because their bodies are adapted to high salt concentrations of the marine
environment. In water conditions, they are unable to control the water entering their body
(through osmosis). Water enters their body due to the hypotonic environment outside. This ends
up in the swelling up of the body, eventually resulting in the death of the marine fish.
3. Most living organisms cannot survive at temperatures above 45°C. How are some
microbes able to live in habitats with temperatures exceeding 100°C?
Ans: In hot water springs and deep sea hydrothermal vents, archaebacteria (thermophiles) grow.
They are able to survive in high temperatures (which far exceed 100°C) because their bodies
have adapted to such environmental conditions. Organisms that withstand high temperatures
contain enzymes with specialized thermal-resistance in order to perform metabolic functions.
7. An orchid plant is growing on the branch of a mango tree. How do you describe this
interaction between the orchid and the mango tree?
Ans: An orchid growing on a mango tree branch is an epiphyte. Epiphytes are plants growing on
other plants which however, do not derive nutrition from them. This relationship therefore exists
as commensalism . There is a commensalism between a mango tree and an orchid, where one
species benefits from the other while the other remains unaffected. The orchid is benefited by the
above interaction because it receives support, while the mango tree remains unaffected.
8. What is the ecological principle behind the biological control method of managing pest
insects?
Ans: Variable biological control methods are based on a concept known as predation. In
predation, the predator feeds on the prey. Hence, predators regulate the population of prey in a
habitat, helping in the control of pest insects.
Bears and squirrels inhabiting cold regions are Fishes and snails are examples of
examples of animals that hibernate during winters. organisms aestivating during summers,
Ectotherm Endotherm
Ectotherm are cold blooded animals, Endotherms are warm blooded animals. They maintain
their temperature varies with their a constant body temperature. Birds and mammals are
surrounding endothermic animals.
Water deficiency is another factor that forces animals to undergo certain adaptations to suit their
natural habitat. Animals found in deserts such as desert kangaroo rats, lizards, snakes, etc. are
well adapted to stay in their habitat. The kangaroo rat found in the deserts of Arizona never
drinks water in its life. It has the ability to concentrate its urine to conserve water. Desert lizards
and snakes bask in the sun during early morning and burrow in the sand as the temperature rises
to escape the heat of the day. Such adaptations can be used to stop the loss of water.
Soil: The nature and qualities of soil vary greatly depending on where you are. It is mostly
determined by the following factors
The weather
The weathering procedure
The process of soil growth
The soil's water holding capacity and percolation are determined by a variety of factors,
including soil chemistry, grain size, and aggregation. The sort of plants that can grow in a
particular habitat is determined by these qualities of soil, as well as its pH, mineral content,
topography, and other factors.
Water: Water is known to have given birth to life on Earth, and it is impossible to survive
without it. The pH, chemical composition, and temperature of water are all vital to aquatic
creatures. They are also affected by water salinity, which ranges from less than 5 parts per
thousand in inland water to 30-35 parts per thousand in the sea and 100 parts per thousand in
some hypersaline lagoons. Euryhaline organisms can tolerate a large range of salinity, whereas
stenohaline organisms can only tolerate a narrow range. Because of osmotic difficulties induced
by high salt, many freshwater creatures cannot thrive in sea water for long periods of time, and
vice versa. A range of factors, including soil chemistry, grain size, and aggregation, influence the
water retention capacity and percolation of the soil. These properties of soil, as well as its pH,
mineral content, topography, and other elements, affect the types of plants that can flourish in a
given habitat. Stenohaline creatures can only survive a narrow range of salinity, but euryhaline
species can withstand a wide range of salt. Many freshwater organisms cannot survive in sea
water for lengthy periods of time due to osmotic issues caused by excessive salt levels, and vice
versa.
Light: The importance of light stems from the fact that all autotrophs rely on it as a source of
energy for photosynthesis, which involves the release of oxygen. Because they are obscured by
towering, canopied trees, small shrubs and plants growing in forests have adapted to
photosynthesis at very low light intensities. The majority of plants rely on sunshine to survive.
Many animals use diurnal and seasonal light intensity variations as cues to time their feeding,
reproductive, and migratory activity. Because the sun is the source of both, the availability of
light on land is directly tied to that of warmth. The environment is constantly gloomy in deep
oceans (> 500m). Solar radiation's spectrum purity is also critical for life.
For marine plants living at different depths of the ocean, different components of the visible
spectrum are available. UV light is harmful to many organisms. As a result, distinct species of
algae, such as green, brown, and red algae, can be found at the upper, middle, and deep layers of
the sea, respectively.
14: Define the following terms and give one example for each:
(a) Commensalism
(b) Parasitism
(c) Camouflage
(d) Mutualism
(e) Interspecific competition
Ans:
(a) Commensalism: Commensalism is an interaction between two species in which one species
gets benefited while the other remains unaffected. An orchid growing on the branches of a
mango tree and barnacles attached to the body of whales are examples of commensalisms.
(b) Parasitism: It is an interaction between two species in which one species (usually smaller)
gets positively affected, while the other species (usually larger) is negatively affected. An
example of this is liver fluke. Liver fluke is a parasite that lives inside the liver of the host body
and derives nutrition from it. Hence, the parasite benefits as it derives nutrition from the host,
while the host is negatively affected as the parasite reduces the host fitness, making its body
weak.
(c) Camouflage: is a strategy adapted by prey species to escape their predators. Organisms are
cryptically coloured so that they can easily mingle in their surroundings and escape their
predators. Many species of frogs and insects camouflage in their surroundings and escape their
predators.
(d) Mutualism: It is an interaction between two species in which both species involved are
benefited. For example, lichens show a mutual symbiotic relationship between fungi and blue
green algae, where both are equally benefited from each other.
(e) Interspecific competition: It is an interaction between individuals of different species where
both species get negatively affected. For example, the competition between flamingoes and
resident fishes in South American lakes for common food resources i.e, zooplankton.
15: With the help of a suitable diagram describe the logistic population growth curve.
Ans: Yeast cells grown under laboratory conditions commonly exhibit the logistic population
growth curve. There are five phases: the lag phase, the positive acceleration phase, exponential
phase, negative acceleration phase, and stationary phase.
Lag Phase: Initially, the population of the yeast cell is very small. This is because of the
limited resources present in the habitat.
Positive Acceleration Phase: In this phase, yeast cells adapt to the new environment and
start to multiply. However, at the beginning of this phase, the growth of the cell is very
limited.
Exponential Phase: During this phase, the population of the yeast cell increases
suddenly due to rapid growth. Due to sufficient food resources, a constant environment,
and the absence of interspecific competition, the population grows exponentially. As a
result, the curve rises steeply upwards.
Negative Acceleration Phase: During this phase, environmental resistance increases and
the population growth rate decreases. This occurs because of an increased completion
among the yeast cells for food and shelter.
Stationary Phase: During this phase, the population becomes constant. A population's
number of cells equals its number of cells that die. Additionally, the species is said to
have reached the carrying capacity of its habitat.
(Image will be uploaded soon)
Parasitism is an interaction between two species, in which one species (parasite) benefits from
the other. The other species (host) is harmed. For example, ticks and lice (parasites) can be found
on the body. This means there is an interaction between parasites and the human body, from
which ticks and parasites receive benefit (as they are Feeding on human blood). On the other
hand, these parasites reduce host fitness and cause harm to the human body.
19. In which way has the study of biology helped us to control infectious diseases?
Ans: In the field of biology, various advancements once a person starts taking alcohol or drugs
have helped us in gaining a better understanding to fight against various infectious diseases.
Biology has helped us in studying the life cycle of various parasites, pathogens, and vectors
along with their modes of transmission and controlling measures. Vaccination programs against
several infectious diseases such as smallpox, chickenpox, tuberculosis, etc. have helped nearly
eradicate these diseases. In the preparation of newer or safer drugs and vaccines, biotechnology
has helped a lot. In treating infectious diseases the antibiotics have also played a very important
role.
20. How does the transmission of each of the following diseases take place?
(a) Amoebiasis
(b) Malaria
(c) Ascariasis
(d) Pneumonia
Ans:
Causative
Disease Mode of Transmission
Organism
(c) Ascaris It spreads via contaminated food and water through faecal-
Ascariasis lumbricoides oral transmission.
24. The following are some well-known abbreviations, which have been used in this
chapter. Expand each one to its full form:
(a) MALT
(b) CMI
(c) AIDS
(d) NACO
(e) HIV
Ans: The abbreviations with their full forms are as follows:
(a) MALT – Mucosa – Associated Lymphoid Tissue
(b) CMI – Cell-Mediated Immunity
(c) AIDS – Acquired Immunodeficiency Syndrome
(d) NACO – National AIDS control organization
(e) HIV – Human Immunodeficiency Virus
25. Differentiate the following and give examples of each:
(a) Innate and acquired immunity
Ans:
It is inherited from parents and protects It does not remain present in the individual from birth
the individual from birth. but is acquired after birth.
This type of immunity provides barriers It operates by providing primary and secondary
against the entry of foreign infectious responses, which are mediated by B-lymphocytes and
agents. T-lymphocytes.
Microbes are injected inside the body through The transfer of antibodies that are present in
the process of vaccination. This is an example the mother’s milk, to the infant is an example
of active immunity. of passive immunity.
In diagram
(a) Antigen binding site
(b) Light chain
(c) Disulphide bridges
(d) Constant region
(e) Heavy chain
(f) Variable region of light chain
(g) Constant region of light chain
(h) Disulphide bonds
27. What are the various routes by which transmission of the human immunodeficiency
virus takes place?
Ans: AIDS (Acquired Immunodeficiency Syndrome) is caused by the Human Immunodeficiency
Virus (HIV). The various modes of transmission of this virus are:
a. Making unprotected sexual contact with an infected person.
b. Transfusion of an infected person’s blood to a healthy person.
c. Sharing of infected needles and syringes.
d. Through the placenta from an infected mother to a child.
28. What is the mechanism by which the AIDS virus causes deficiency of the immune
system of the infected person?
Ans: AIDS (Acquired Immunodeficiency Syndrome) is caused by the human immunodeficiency
virus (HIV) through sexual or blood-blood contact. After entering the human body, HIV attacks
and enters the macrophages. The RNA of the virus replicates with the help of enzyme reverse
transcriptase and gives rise to viral DNA, inside the macrophages. After this, the viral DNA is
incorporated into the host DNA and directs the synthesis of virus particles. Simultaneously, HIV
enters into the helper T-lymphocytes. There it replicates and produces viral progeny. Now, these
newly formed progeny viruses get released into the blood, attacking other healthy helper T
lymphocytes in the body. As a result, the number of T-lymphocytes in the body of an infected
person decreases progressively and hence decreases the immunity of a person.
31. Do you think that friends can influence one to take alcohol/drugs? If yes, how may one
protect himself/herself from such an influence?
Ans: Yes, I think that friends can highly influence a person to take drugs or alcohol. Following
steps should be taken by a person for protecting himself/herself against drug abuse:
(a) Increase your willpower to stay away from alcohol and drugs. For curiosity and fun, one
should not experiment with alcohol.
(b) Avoid the company of drug-taking friends.
(c) Seek help from parents and peers.
(d) Take proper knowledge and counseling about drug abuse and devote your energy to other
extracurricular activities.
(e) If symptoms of depression and frustration become apparent, seek immediate professional and
medical help from psychologists and psychiatrists.
32. Why is it that it is difficult to get rid of this habit once a person starts taking alcohol or
drugs? Discuss it with your teacher.
Ans: Drug and alcohol consumption has an inherent addictive nature related to euphoria and a
short-lived feeling of well-being. Repeated intake of medicine increases the tolerance level of the
body’s receptors, resulting in more consumption of medicine.
33. In your view what motivates youngsters to take to alcohol or drugs and how can this be
avoided?
Ans: Many factors are liable for motivating youngsters towards alcohol or drugs. The initial
causes of motivation are curiosity, the need for adventure and excitement, experimentation.
Some youngsters start consuming drugs and alcohol to beat negative emotions (such as stress,
pressure, depression, frustration) and to excel in various fields. Several mediums like television,
the internet, newspaper, movies, etc. are also responsible for promoting the idea of using alcohol
for fun to the younger generation. Among these factors, reasons such as unstable and
unsupportive family structures and peer pressure can also lead an individual to depend on drugs
and alcohol. Preventive measures that work against addiction to alcohol and drugs too are given
below:
(a) Parents should motivate and try to increase the willpower of their children.
(b) Parents should educate their children regarding the ill effects of alcohol. They should provide
them with proper knowledge and counselling regarding the consequences of addiction to
alcohol.
(c) It’s the responsibility of the parent to discourage a toddler from experimenting with alcohol.
Youngsters should be kept far away from the company of friends who consume drugs.
(d) Children should be encouraged to devote their energy to other extra-curricular and
recreational activities.
(e) Proper professional and medical help should be provided to the child if sudden symptoms and
depression and frustration are observed.
34. Mention the advantages of selecting pea plants for experiments by Mendel.
Ans: The pea plant (Pisum sativum) was chosen by Mendel for the following reasons:
1. The pea is an annual plant with a brief growing season. As a result, the findings can be
achieved in a short amount of time.
2. Pea has seven distinct features with easily distinguishable traits such as tall and short
stature, round and yellow seeds, and so on.
3. Self-pollination and cross-pollination are both viable options for pea propagation. Mendel
was able to create pure lines as well as carry out various crosses between plants with
contrasting features as a result of this.
4. Each generation of the pea plant produces a great number of seeds. As a result, it can
provide a vast volume of data that can be statistically more reliably analyzed, for
example.
Dominance Recessive
1. A trait that counteracts the effects of 1. A trait that is suppressed as a result of the effect
another trait, such as tallness suppressing of another attribute. Dwarfness, for example, is
dwarfism. suppressed by height.
2. A trait that will manifest itself even if 2. A trait that only manifests when the dominant
the recessive trait is present. trait is absent.
3. A trait that manifests in both 3. A trait that can only be expressed in homozygous
homozygous and heterozygous individuals.
individuals.
Homozygous Heterozygous
1. For a trait, a genotype is made up of alleles that are 1. For a trait, a genotype with
similar. TT (for tall) or tt are examples of abbreviations different alleles. e.g. Tt.
(for short).
2. The person could be dominant or recessive. Individuals 2. The person is usually dominant or
with the TT genotype, for example, will be tall plants, but partially dominant, but never
those with the tt genotypes will all be short plants. recessive.
3. Individuals will only create one type of gamete. T or t 3. The person will create two
for example different types of gametes. Both T
and t gametes, for example.
Monohybrid Dihybrid
2. A monohybrid cross is a cross between 2. A dihybrid cross occurs when two parents are
two parents that are homozygous for homozygous for opposing features in two different
opposing character characteristics. For characters, such as seed shape and seed color. A
example, a cross between tall TT and cross between RRYY (round and yellow seeds) and
short (S) tt. rryy, for example (wrinkled and green seeds).
40. When a cross is made between tall plants with yellow seeds TtYy and tall plant with
green seed TtYy, what proportions of phenotype in the offspring could be expected to be
(a) Tall and green. (b) Dwarf and green.
Ans: When tall plants with yellow seeds (TtYy) are crossed with tall plants with green seeds
(TtYy), The phenotypic proportion in the progeny should be three tall and green, one dwarf and
green.
TY Ty tY ty
41. Two heterozygous parents are crossed. If the two loci are linked what would be the
distribution of phenotypic features in F1 generation for a dihybrid cross?
Ans: When two genes are inherited together, they are referred to as linked genes, and linkage is
the term used to describe this process. There will be no segregation of alleles if two genes are
connected, and the alleles will be inherited together as a single gene. If two genes are connected,
the phenotype of the F1 generation will solely contain parental features and no recombinants.
There may be few recombinants in the case of inadequate linkage, but the proportion of parental
phenotypes will be higher.
43. What is pedigree analysis? Suggest how such an analysis can be useful.
Ans: Pedigree Study is a type of genetic analysis in which the inheritance of a specific gene is
traced through a person's lineage. It is accomplished by the use of a pedigree chart, which is a
scientific chart of ancestors produced using precise symbols to identify male, female, carrier,
disease, and so on. The following are some of the benefits of pedigree analysis:
1. Determine whether the gene is homozygous or heterozygous or homozygous or
heterozygous for heterozygous or homozygous or heterozygous or homozygous or
heterozygous for homozy
2. Examination of the gene's inheritance over successive generations of the same family.
3. Determine whether a particular genetic condition is caused by a dominant or recessive
gene.
4. To look into the origins of the sickness in the family and try to figure out what caused it.
5. To determine whether or not this gene will be passed down via future generations, as well
as the likelihood of this happening.
6. To provide genetic counseling to families who are at high risk for various genetic
disorders such as hemophilia, sickle cell anemia, and so on.
47. Mention any two autosomal genetic disorders with their symptoms.
Ans:
a.Sickle Cell Anemia - When glutamic acid is replaced by valine in the sixth position of the beta
globin chain of hemoglobin due to a point mutation, the biconcave shape of hemoglobin
transforms into a sickle shape. This causes a reduction in blood oxygen delivery, as well as
weakness and fatigue.
b.Phenylketonuria - Phenylketonuria is a condition in which a person lacks an enzyme that
transforms amino acids and phenylalanine to tyrosine. The phenylalanine then builds up and is
converted to phenyl pyruvic acid and other derivatives. Mental retardation is a symptom of this
disease. They are eliminated in the urine due to inadequate renal absorption.