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    Table 7-13 Antidepressants For Geriatric Patients

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    Table 7-13 Antidepressants For Geriatric Patients

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    147 views2 pages

    Table 7-13 Antidepressants For Geriatric Patients

    Uploaded by

    Dragutin Petrić
    a

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Essentials of Clinical Geriatrics, 7e >Chapter 7.

    Diagnosis and Management of Depression


    Robert L. Kane, Joseph G. Ouslander, Itamar B. Abrass, Barbara Resnick+
    Table 7–13. Antidepressants for Geriatric Patients

    Drug group generic name (brand name) Drug group side effects Special concerns with older adults

    Tricyclic antidepressants

    Dry mouth
    Amitriptyline (Elavil)
    Blurred vision
    Amoxapine (Asendin)
    Clomipramine (Anafranil) Constipation
    Desipramine (Norpramin or Pertofrane) Difficulty urinating
    Doxepin (Sinequan or Adapin) Increased heart rate These drugs are best avoided because of the side effects
    Imipramine (Tofranil) Loss of sex drive and erectile failure Amoxapine can cause extrapyramidal effects
    Maprotiline (Ludiomil) Increased sensitivity to the sun
    Nortriptyline (Pamelor or Aventyl) Weight gain
    Protriptyline (Vivactil)
    Drowsiness
    Trimipramine (Surmontil)
    Dizziness and nausea

    MAOIs

    Light-headedness upon standing


    Dizziness
    Phenelzine (Nardil) Insomnia
    All foods and drinks containing tyramine must be avoided, or the
    Tranylcypromine (Parnate) Weight gain
    patient may experience a hypertensive crisis, stroke, or myocardial
    Isocarboxazid (Marplan) Headaches
    Selegiline (Emsam) infarction
    Insomnia
    Sexual problems such as impotence
    Sleepiness

    SSRIs

    Nausea
    Insomnia
    Anxiety and restlessness SSRIs can cause an increase in suicidal thoughts and behaviors
    Decreased sex drive SSRIs also carry a risk for increased hostility, agitation, and
    Fluoxetine (Prozac)
    Fluvoxamine (Luvox) Dizziness anxiety
    Sertraline (Zoloft) Weight gain or weight loss SSRIs should not be taken at the same time as MAOIs
    Paroxetine (Paxil) Tremors Taking an SSRI within 2 weeks of an MAOI can cause a fatal
    Escitalopram (Lexapro) Sweating reaction
    Citalopram (Celexa) Drowsiness or fatigue In adults 65 and older, SSRIs increase the risk for falls, fractures,
    Duloxetine (Cymbalta) Dry mouth and bone loss
    Mirtazapine (Remeron)
    Diarrhea or constipation Mirtazapine causes significant sedation and weight gain so is
    Headaches effective for those with sleep disorders and weight loss
    Nausea
    Nervousness

    Atypical antidepressants

    Sexual dysfunction
    Bupropion (Wellbutrin) Dry mouth Venlafaxine should not be used in those with hypertension
    Trazodone (Desyrel) Fatigue Duloxetine may be effective in those suffering from both
    Venlafaxine (Effexor) Sleepiness depression and pain
    Nefazodone (Serzone) Weight gain Nefazodone may cause hepatotoxicity
    Blurred vision

    MAOIs, monoamine oxidase inhibitors; SSRIs, selective serotonin reuptake inhibitors.


    Date of download: 12/29/22 from AccessMedicine: accessmedicine.mhmedical.com, Copyright © McGraw Hill. All rights reserved.

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