4 - 5 Weeks AOG 3 Trimester: Period
4 - 5 Weeks AOG 3 Trimester: Period
4 - 5 Weeks AOG 3 Trimester: Period
MATERNAL DEVELOPMENT
6 Weeks AOG Within the 6mbryonic period
No obvious signs of abdominal enlargement
After 8 Weeks Fetal period
12 Weeks AOG 12etal period
Fetus is at fetal period
20 Weeks AOG Midp20int pregnancy
Fundus = level of umbilicus
22 Weeks AOG 2 (Congenital anomaly ultrasound performed) 2
28 Weeks AOG 2 + 8 = 1kg
Fetus approximately 1kg
37 Weeks AOG Delivery is possible
39 Weeks AOG 3version of the N9vel
40 Weeks AOG Used to compute the Naegele’s rules
PHYSIOLOGICAL CHANGES
By 12 Weeks - UTERUS Globular & Spherical
The ovarian ligaments are attached slightly above the middle
of the corpus
HORMONES IN PREGNANCY
B-hCG Maintains corpus luteum
Estrogen Prepares maternal body for delivery by increasing oxytocin receptors in the uterus
Progesterone SM relaxant & maintains uterine lining
PHYSIOLOGIC CHANGES
Respiratory System Intra-abdominal Pressure -> more diaphragmatic breathing ->
Hyperventilation & Tidal volume
Cardiovascular Changes in Cardiovascular Output (HR & SV)
Systemic Vascular Resistance = SV
34 Weeks H3m4tological Change: peak in plasma volume (40%) that contributes to
edema
Red Cell volume (25%)
Anemia in Pregnancy Red Cell volume (25%): Net less RBC / volume
peak in plasma volume (40%)
due to larger % increase in plasma volume
Hypercoagulable state in Clotting factors
Pregnancy DEEP VEIN THROMBOSIS
UNCHANGED
1. RR
2. Gastric Emptying (prolonged during labor)
3. Upper Extremity Venous Pressure
4. Excretion of Na & Potassium (there is increased tubular reabsorption)
5. B lymphocyte number
6. Ratio of CD4 to CD8 lymphocytes
DECREASED
1. IL2
2. INF-Y Pregnancy suppresses humoral & cell-
3. TNF-B mediated immunological function
4. T helper 1
5. T cytotoxic cell
6. Factors XI, XIII