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    Agus Syarifudin, S.Si Klinik Psikoneurologi Hang Lekiu

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    Ryan Ade Sudarlan
    The document discusses several topics related to aging including the definition of aging, the aging process, gut microbiota and its relation to neuropsychiatric disorders, and anti-aging treatment. It provides definitions of aging from various sources and categorizes levels of being considered old based on physical capacity. It also outlines some principles and questions around anti-aging treatment.

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    Agus Syarifudin, S.Si Klinik Psikoneurologi Hang Lekiu

    Uploaded by

    Ryan Ade Sudarlan
    8 views20 pages
    The document discusses several topics related to aging including the definition of aging, the aging process, gut microbiota and its relation to neuropsychiatric disorders, and anti-aging treatment. It provides definitions of aging from various sources and categorizes levels of being considered old based on physical capacity. It also outlines some principles and questions around anti-aging treatment.

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    Belajar dan belajar

    Original Title

    ANTI AGING

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    The document discusses several topics related to aging including the definition of aging, the aging process, gut microbiota and its relation to neuropsychiatric disorders, and anti-aging treatment. It provides definitions of aging from various sources and categorizes levels of being considered old based on physical capacity. It also outlines some principles and questions around anti-aging treatment.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    8 views20 pages

    Agus Syarifudin, S.Si Klinik Psikoneurologi Hang Lekiu

    Uploaded by

    Ryan Ade Sudarlan
    The document discusses several topics related to aging including the definition of aging, the aging process, gut microbiota and its relation to neuropsychiatric disorders, and anti-aging treatment. It provides definitions of aging from various sources and categorizes levels of being considered old based on physical capacity. It also outlines some principles and questions around anti-aging treatment.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 20

    Agus Syarifudin, S.

    Si
    Klinik Psikoneurologi Hang Lekiu
    AGING
    Ageing process (‘normal ageing’) represents
    the universal biological changes that occur
    with age and are unaffected by disease and
    environmental influences. Not all of these
    age-related changes have adverse clinical
    impacts (WHO, 1999).

    Process of ageing is strongly influenced by


    the effects of environmental, lifestyle and
    disease states that, in turn, are related to or
    change with ageing but are not due to ageing
    itself

    “a persistent decline in the age-specific fitness


    components of an organism due to internal
    physiological degeneration.”
    AGING DEFINITION
    1. Progressive, generalised
    impairment of function
    resulting in a loss of adaptive
    response to stress and in a
    growing risk of age associated
    disease.
    2. Process of growing older
    without growing old through
    the maintenance of physical,
    social, and spiritual activities
    throughout a lifetime’
    Definition of Old
     Based on this physical capacity to
    work, the old are placed in three
    categories:
     (1) Recent old who are still active
    and undertake normal activities
    without support;
     (2) Old who work with difficulty
    and hence have reduced
    activities;
     (3) Very old who work with
    difficulty in the home or not at
    all.
    GUT MICROBIOTA
    GUT MICROBIOTA &
    NEUROPSYCHIATRIC DISORDER
    Anti Aging Treatment
    Anti-aging treatment reveals some
    weaknesses in this standard view, involving
    the following questions.
    1. Is there a real distinction between age-
    related disease and aging?
    2. Where should one draw the line
    between anti-aging treatment and
    conventional treatments for late-life
    diseases?
    3. To what extent do treatments that
    extend lifespan in animal models slow
    aging?
    4. Which is a better defining
    characteristic of anti-aging treatments:
     that they inhibit the central process of
    aging, or that they prevent age-related
    diseases?
    Anti Aging Treatment Definition
    Aging is the set of
    endogenously generated
    pathologies that increase in
    later life, and that anti-aging
    treatments are best defined as
    those that prevent one or more
    pathologies of aging.
    Anti Aging Treatment Principle
    1. A drug or treatment that
    mimics the effect of dietary
    restriction, and inhibits aging
    itself and, thereby, all age-
    related disease.
    2. A treatment or treatment that
    blocks a subset of age-related
    pathology
    3. A drug or treatment that
    protects against a single age-
    related disease
    Reference
    Flatt, T. (2012). A new definition of aging? Frontiers in
    Genetics, 3(148):1-2
    Gems, D. (2014). What is an anti-aging treatment?
    Experimental Gerontology,58(2014) 14–18.
    WHO. (1999). Men ageing and health: Achieving health
    across the life span. WHO: Geneva

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