Validation Test No. 1 in Grade 10 Science Quarter 3 Week 1-4

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Republic of the Philippines

Department of Education
REGION I
SCHOOLS DIVISION OFFICE I PANGASINAN
PANGASINAN SCHOOL OF ARTS AND TRADES
ALVEAR ST., POBLACION, LINGAYEN, PANGASINAN

VALIDATION TEST NO. 1 IN GRADE 10 SCIENCE


QUARTER 3 WEEK 1–4
Direction: Read each question carefully and write only the letter of your answer in one whole sheet of paper or in your Zipgrade Answer Sheet (if
available). DO NOT WRITE ANYTHING ON THIS TEST PAPER.

1. The reproductive system among humans become active when an individual ____________________.
A. grows taller B. is in high school C. is in college D. reaches puberty
2. Which structure is responsible in producing sperm cells?
A. penis B. prostate gland C. scrotum D. testis
3. Which term describes an egg cell?
A. chromosome B. gamete C. gonads D. zygote
4. Which gland regulates the blood sugar level?
A. pancreas B. parathyroid C. pituitary D. thyroid
5. Which system contains a group of glands that release hormones in the body?
A. circulatory system B. endocrine system C. nervous system D. respiratory system
6. It is known as the emergency hormone.
A. adrenalin B. androgen C. estrogen D. progesterone
7. What happens during ovulation?
A. A sperm can fertilize an egg. C. An ovum is released from the ovary.
B. A zygote becomes an embryo. D. A follicle releases the hormone FSH.
8. What results to the disintegration of the endometrium?
A. menarche B. menopause C. menstruation D. miscarriage
9. A biologist made a hypothesis that the pituitary and the ovary both influence the uterine cycle in females. Which observation would best
support this hypothesis?
A. The removal of pituitary is followed by death.
B. The removal of the ovary can greatly affect the menstrual cycle.
C. The removal of the ovary is followed by a non-functioning pituitary.
D. The uterine development takes place only when both pituitary and ovary are present.
10. A woman’s unsafe period is the day near or during ____________________.
A. fertilization B. menstruation C. ovulation D. sexual intercourse
11. What signals the beginning of cyclic changes in the ovary?
A. menarche B. menopause C. LH D. FSH
12. In a typical 28-day menstrual cycle, on which day following the beginning of the menstrual period is the level of luteinizing hormone most
likely to be the highest?
A. day 7 B. day 14 C. day 21 D. day 28
13. It is the central control system of the body.
A. brain B. neurons C. neurotransmitter D. spinal cord
14. Complete this sentence: ____________________ carry all impulses throughout the body to and from the brain.
A. Cerebrum B. Medulla oblongata C. Pons D. Spinal cord
15. Comparing a computer to a neuron, what part could the neuron be?
A. CPU B. keyboard C. monitor D. mouse
16. Describe a synapse.
A. It carries messages to the cell body.
B. It carries messages away from the cell body.
C. It is a gap between the axon and the dendrites of another neuron.
D. It is a gap between the axon and the axon terminal of another neuron.

17. What is an Alzheimer’s disease?


A. a problem within the nerve cells of the brain that controls movement
B. a growth in the brain that leads to increased pressure inside the skull
C. a disease that brings pain and loss of feeling in the feet, legs, and hands
D. a brain damage that causes loss of memory, or problems with speaking and thinking
18. Which disease manifests pressure inside the skull or destruction and compression of the normal brain tissue that leads to function loss?
A. aphasia B. brain tumor C. epilepsy D. meningitis
19. According to the central dogma, which of the following represents the flow of genetic information in cells?
A. protein to DNA to RNA C. RNA to DNA to protein
B. DNA to RNA to protein D. DNA to protein to RNA
20. Protein synthesis refers to the ____________________.
A. process of formation of amino acids from mRNA
B. process of formation of mRNA from DNA template
C. process of duplicating DNA required for protein synthesis
D. process of formation of amino acids directly from a DNA template
21. Which molecule contains the genetic code?
A. rRNA B. tRNA C. DNA D. mRNA
22. What is the complementary messenger-RNA sequence for the DNA template sequence shown below?
C-A-A-G-G-T
A. GTTCCA B. CAAGGU C. GUUCCA D. CAAGGT
23. Which statement is correct?
A. Termination codon has no tRNA
B. CTP is required for amino acid activation
C. There is only one amino acid acyl-tRNA synthetase in a cell
D. Activated amino acid binds to the 5’ end of respective tRNA molecule
24. Which is NOT a requirement for protein synthesis?
A. ribosomes B. peptidyl transferase C. spliceosome D. amino acid tRNA synthase
25. Which types of mutation can result in a frameshift?
A. Insertions and deletions B. Missense and deletions C. Nonsense and insertions D. Nonsense and missense
26. Which type of mutation does NOT change the overall function of the protein?
A. Insertion B. Missense C. Nonsense D. Silent
27. Which karyotyping technique is used to detect abnormalities?
A. amniotic fluid B. blood and urine C. chromosomes D. ribosomes
28. Which of the following is a possible result of chromosomal breakage that a fragment can be reattached to the original chromosome in a
reverse orientation?
A. deletion B. disjunction C. inversion D. translocation
29. In a family, a father is having a disease and the mother is normal. The disease is inherited to only daughters and not to the sons. What type
of disease is this?
A. autosomal dominant B. autosomal recessive C. sex-linked dominant D. sex-linked recessive
30. Down’s syndrome is characterized by:
A. 19 Trisomy B. 21 Trisomy C. Two X and one Y chromosome D. Only one X chromosome

Prepared by:

ORLAN V. SISON ALIZA MARIE S. SAGUN, PhD MA. ESTER BERLIESE F. DE VERA
Teacher III Teacher III Teacher I

Recommending Approval: Approved:

VERGIE V. JORDA ROSARIO C. FERRER, EdD


Head Teacher VI (Science Department) Principal IV

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