SPECT

Preclinical Imaging Systems

SPECT/MRI
SPECT/CT
 MEDISO Medical Imaging Systems

Tradition in research and development

Mediso is a global company with headquarter in the European Union in Budapest Hungary. Mediso is a dynamic manufacturer
of nuclear medicine and modern hybrid imaging equipment, which it supplies and supports to healthcare, research institutes
and industry worldwide. The company was founded in 1990 and is world leading in R&D and commercialization of cutting
edge preclinical and clinical medical imaging systems.

Latest awards

2012 - Frost & Sullivan 2012 European Preclinical Imaging

New Product Innovation Award
2011 - Grand Prize of Innovation 2010
2008 - Frost & Sullivan 2008 European Medical Imaging
Entrepreneurial Company of the Year Award
2006 - Grand Prize of Innovation 2006

University and clinical diagnostic partners

Mediso have developed special partnership with pre-clinical imaging contract research organizations and leading molecular
imaging centers in both preclinical and clinical field around the world.

Partnership with Karolinska Institutet ( Sweden), King’s College London (UK), Semmelweis University and CROmed in preclinical
imaging field. University of Debrecen Medical School, Hungarian National Institute of Neuroscience and Scanomed in clinical
area represents a key drive to Mediso’s research and developments.

www.cromedresearch.com www.scanomed.hu

Customer focused support

Mediso-affiliated subsidiaries and world-wide distributor network with strong factory support ensure direct contact
with our customers and quick, professional response to their requests not only in technical but also in application related
issues. We at Mediso are proud to serve physicians and researchers at sites with more than 100 preclinical and 900 clinical
installed systems in 86 countries.

Pursuit of perfection in technology to serve perfection in science

Always eager to find an even better solution, Mediso constantly strive to develop the highest level
medical imaging technologies possible.

We wish to serve the scientific community with our core value: supreme image quality with
2 accurate quantification.
nanoScan® SPECT/MRI and SPECT/CT

Overview
Preclinical SPECT/MRI and SPECT/CT combine the best of ultra-high SPECT resolution and ultra-high anatomical resolution
with soft tissue contrast. Mediso’s nanoScan® SPECT is highly sensitive with the ability to also perform simultaneous
multiisotope imaging (i.e. the ability to probe two or more molecular pathways simultaneously by detecting isotopes
with different emission energies). SPECT’s relatively long-lived radioisotopes render SPECT/MRI and SPECT/CT ideal for
pharmacokinetic studies of peptides and antibodies, which are readily radiolabelled, and easily translated in to the clinic.
Mediso’s nanoScan® SPECT/MRI is the only commercial fully integrated scanner. The nanoScan® SPECT/MRI is high
throughput, easy to use and virtually maintenance free with the advantage of enabling automatic co-registration of SPECT
with MRI – a challenge to achieve with two independent non-integrated systems. The sensitivity of the ultra-high resolution
Mediso nanoScan® SPECT/MRI and SPECT/CT make them ideal for 3D quantitative dynamic in vivo molecular imaging.

nanoScan® SPECT/MRI and nanoScan® SPECT/CT

With the nanoScan® Family concept Mediso provides unique and flexible solution for the demands of your imaging facility.
Members of the nanoScan® Family share the similar easy to use, software platform (Nucline™ acquisition software) for all
modalities, with intuitive workflow and incorporated effortlessly customizable protocols.

For analysis both InterView™ FUSION and VivoQuant™ can co-register and analyze multiple images across all modalities.

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 Under the hood SPECT/MRI

Touchscreen interface

- Shared interface for SPECT and MRI

- Bed movement control through touchscreen
interface or from the acquisition workstation
- Online animal vital function monitoring
- SPECT persistence scope function

SPECT Detector

- up to 250 mm transaxial FOV

- 300 µm spatial resolution
- 13 000 cps/MBq sensitivity
- Patented M3 multipinhole technology
- Up to 144 pinholes

Animal handling

- Direct access possibility to the animal during scan

- Zero dead space: easy manipulation of the animal
(injection, blood sampling, etc.)
- Automated bed positioning
- Integrated heating and gas anaesthesia possibility
- Physiology monitoring
- ECG/respiratory gating

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 MRI Magnet
- 1 Tesla permanent magnet
- Gradient strength: 450 mT/m
- < 5 ppm homogenity
- 100 μm spatial resolution
- Integrated gradient coil
- Integrated RF shielding

RF Coils

- Back door access for easy coil exchange

- Multiple solenoid coils available
- 35 mm Tx/Tr for mouse whole body imaging
- 60 mm Tx/Tr for rat whole body imaging
- Custom coils available upon request

Fast, Easy Instrument Installation

- Cryogen-free design
- Compact size: 1136 x 2177 x 1550 mm
- Weight: 1880 kg
- Zero magnetic fringe field
- No need for additional RF shielding in the lab

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 Under the hood SPECT/CT

Touchscreen interface

- Shared interface for SPECT and CT

- Bed movement control through touchscreen
interface or from the acquisition workstation
- Online animal vital function monitoring
- SPECT persistence scope function

Animal handling

- Direct access possibility to the animal during scan

- Zero dead space: easy manipulation of the animal
(injection, blood sampling, etc.)
- Automated bed positioning
- Integrated heating and gas anaesthesia possibility
- Physiology monitoring
- ECG/respiratory gating

High Precision Gantry

- Precise and robust rotational bearing and drive

- Exceptionally stable gantry with 3 axis movements
- Large bore size up to 200 mm
- Touchscreen interface
- Vibration free rubber pads

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 SPECT Detector

- up to 250 mm transaxial FOV

- 300 µm spatial resolution
- 13 000 cps/MBq sensitivity
- Patented M3 multipinhole technology
- Up to 144 pinholes

Upgrade with PET subsystem to an integrated

triple modality nanoScan® SPECT/CT/PET

PET Subsystem

Coincidence based full LYSO ring PET subsystem with various

detector configurations (module / block): 8/1, 8/2, 12/1, 12/2

Full functionality Tera-Tomo™ 3D PET reconstruction software

with embedded corrections for accurate quantification with
high resolution up to 0.7 mm and high sensitivity 9%

For further details on this option please refer to the PET based
preclinical imaging system brochure or contact your local
sales representative.

X-Ray CT System

- 80 W/1 mA X-ray tube power

- <10 mGy exposure CT dose
- 2-12 cm variable TFOV
- x 7,6 zoom
- < 10 µm isotropic voxel size

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 SPECT subsystem
Mediso, world leaders in SPECT R&D
Mediso as manufacturer and developer with more than 20 years of expertise in clinical and preclinical SPECT technology offers
its newest design that fine tunes SPECT performance from detection through collimation to reconstruction. This results in high
resolution and high sensitivity at the same time.

Detectors
The ultra high performance (UHP) detector technology is
the key component of the SPECT system. The option UHP
to choose different crystal thickness allows for the Detector
study of a wide range of isotopes including high Technology
energy isotopes (20-600 keV).

Reconstruction
The Tera-Tomo™ 3D SPECT reconstruction Wide range
is a 3D iterative SPECT reconstruction
software which includes various of dynamic FOV
corrections such as MRI or CT
based attenuation, scatter and with high resolution
real time Monte Carlo based Tera-TomoTM & high sensitivity M3 pinholeTM
detector modeling. 3D SPECT
Collimator
The list mode data collection Reconstruction
Technology
makes the data processing even Technology
more accurate and flexible with
unprecedented results in image
quality and quantification.

Collimators
Mediso developed the new Multifocus, Multisize, Multi-pinhole (M3) apertures where the projections are linked to the best
intrinsic resolution of the detector area. The novelty of the technology, using the multi-size holes combined with multiple
focusing pinholes allows for optimization for any given specific application. The M3-pinhole technology also allows for the
fine tuning of the imaging parameters to maximize the resolution-efficiency tradeoff. Various apertures are available from
whole body to organ, from ultra high sensitivity to ultra high resolution in addition to a number of parallel hole collimators.

MIP image of a whole body helical mouse

scan. 35 MBq 99mTc MDP, 180 min p.i.
0.35 0.30

0.40 0.25

Imaging performance with Tera-Tomo™

3D SPECT Reconstruction software using
60 MBq 99mTc-pertechnetate SPECT acquisition in 0.50 0.60
8
a micro Derenzo phantom.
Size of the rods: 0.25 mm – 0.60 mm
 Why choose nanoScan® SPECT?
- Wide range of FOV from mouse organ to rabbit or even monkey whole body
- Largest multi-pinhole field of view without the need for bed movement
- Full stationary ultra-fast dynamic imaging capabilities
- Highest volume sensitivity with single bed position even with large FOV
- Unprecedented uniformity in projections and detector coverage by 4 detector heads
- The only SPECT system to be fully integrated with MRI
- Application specific apertures with ultra high sensitivity and ultra-high resolution for whole body to organ specific imaging
- Fast and intuitive workflow with built in and semi-automated functions into the acquisition hardware and software (e.g.
video & vital monitoring, temperature control, respiratory and cardiac gating).
- Easy to use animal handling accessories that can be customized to specific user requirements
- Unique versatility in upgrade possibilities including field upgrade, add-on upgrade and split upgrade that allows
customized growth in imaging capacity.
Dynamic Kidney
DynamicStudy
Kidney Study 3 sec
40

Activity Concentration
35

Full stationary ultra-fast dynamic SPECT3imaging

40
sec time frame
30

Activity Concentration
35

(MBq/ml)
VOI selection VOI selection Sum of all time Sum
frames
of all 40
time frames 25
3 sec time frame 30
Activity Concentration

35 20
MIP image of uptake in mouse

(MBq/ml)
3D visualization40of 25
3 sec time frame 30 kidney,
15 sum of all time frames.
Activity Concentration

VOI selection for

35 20 18.3 MBq 99mTc MAG3 was
(MBq/ml)

40 TAC evaluation 25 10
3 sec time frame 30 15 injected.
Activity Concentration

35 20 5
(MBq/ml)

25 10
time frame 30
20
15 0
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(MBq/ml)

25 0 100 200 300

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10 0 100 200 300 400
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Kidney500Cortex Elapsed Ti
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Kidney CortexTime (s) 800 Pelvis
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(MBq/ml)

25 0 100 200 300 400Vein 500 R Kidney R Kidney Pelvis

600 700 800 900 L Kidney Cortex
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R Kidney CortexTime (s)
R Kidney Pelvis L Kidney Cortex L Kidney Pelvis
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200 courtesy
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at European InstituteatforEuropean
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Elapsed Time (s)
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VeinCurve of full stationary
R Kidney ultra-fast dynamic
Cortex imaging
R Kidney Pelvis L Kidney Cortex L Kidney Pelvis

Tera-Tomo™ 3D SPECT reconstruction software

Tera-Tomo™ 3D SPECT reconstruction incorporates various corrections to further enhance quantification of the SPECT data.
Real time Monte Carlo based detector modeling, attenuation and scatter correction based on MRI or CT images, detector
crystal modeling and accurate geometric calibration adds to the supreme accuracy and resolution of the reconstructed
images. Furthermore the iterative Tera-Tomo™ 3D SPECT reconstruction is implemented on GPU cluster to further speed up
the reconstruction process.

Monte Carlo Regularized

Photon transport High precision,
based Monte Carlo based OSEM
modeling quantitativ,
pinhole edge crystal interaction reconstruction
(attenuation, fast 3D SPECT
penetration modeling implemented
scatter) reconstruction
modeling on multi GPU
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 SPECT subsystem

Wide range of customizable collimator field

of views to meet all your application needs

One bed position FOV

Application Type of collimator
(diameter x length)

Mouse organ (focused) multi-pinhole 12 x 7 mm

Mouse whole body and rat organ multi-pinhole 30 x 12 mm

Rat whole body multi-pinhole 58 x 20 mm

Monkey brain* multi-pinhole 80 x 45 mm

Rabbit whole body* parallel hole 160 x 250 mm

Monkey whole body parallel hole 220 x 250 mm

And many more

Basic multi-pinhole collimators

Illustration of field of view:
M3 High Resolution, High Sensitivity Mouse Whole Body Whole body mouse, Monkey head,
- 16 pinhole / aperture Monkey whole body respectively
- Resolution 0.85 mm
- Sensitivity 7500 cps / MBq
- FOV: Ø 30 x 300 (with helical scanning)

M3 High Resolution, High Sensitivity Rat Whole Body

- 16 pinhole / aperture
- Resolution 1.1 mm
- Sensitivity 3000 cps / MBq
- FOV: Ø 58 x 300 (with helical scanning)

Optional multi-pinhole collimators

- M3 High energy Mouse Whole Body aperture
- M3 High energy Rat Whole Body aperture
- M3 High resolution focusing mouse aperture (25 pinhole / aperture)
- M3 High resolution focusing rat aperture (25 pinhole / aperture)
- M3 High sensitivity focusing mouse aperture (36 pinhole / aperture)
- M3 High sensitivity focusing rat aperture (25 pinhole / aperture)

Optional collimators (for larger animals)

- Parallel hole low energy ultra high resolution (LEUHR) collimator
- Parallel hole low energy high resolution (LEHR) collimator
- Parallel hole low-energy general purpose (LEGP) collimator
MIP image of whole body
- Parallel hole medium-energy general purpose (MEGP) collimator helical rat scan.
- Parallel hole high-energy general purpose (HEGP) collimator 60 MBq 99mTc MDP, 60 min p.i.
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MRI subsystem

High imaging performance

The compact, high-performance magnet system is developed
by the pioneer in the field of permanent magnet MRI systems
– Aspect Imaging. The filed strength is optimized to perform
fast (sesconds to minutes) routine studies with high resolution
(routinely up to 100 μm) soft tissue contrast. The magnetic
field homogeneity, critical to provide uniform contrast, is
remarkably high with a maximal of 5 ppm throughout the
Field of View in addition to the 450mT/m gradient strength.

Easy-to-use workflow
The MRI system’s ease of use is matched with its powerful
imaging capabilities, making it simple to correlate functional GRE-SP (TE/TR- 3.8/30, FOV = 64, 256*256*48, Flip Angle-25º, NEX-2,
res. 250µm, Acq. Time 12 min) with contrast agent
PET data with anatomical morphology. In addition the Images courtesy of Prof. G. Allan Johnson Center for In Vivo
subsystem is unusually quiet as its whisper gradients generate microscopy- Duke University
less than 20 dB of noise.

Cost effective operation Available solenoid RF coils:

The compact cryogen free design of the system guarantees - 35 mm for whole body mouse
low running costs with a small footprint. The zero fringe field - 60 mm for whole body rat
allows for safe operation with no need for additional magnetic - mouse head coil – optional
shielding in the room and is virtually maintenance free. - rat head coils – optional

Rat Brain MR imaged using

a Fast Spin Echo sequence
TR=3500 ms, 256*256, reso 195
um TE=83 ms, 12 min

Several 2D and 3D pulse sequences

- 3D Localiser - Angiography with contrast agent by Gradient Echo
- Quick sagittal Localiser for ultrafast anatomical reference sequence
- Spin Echo (SE) 2D and 3D - T1-map creation by IR-GRE SNAPSHOT (series of quick
- Fast Spin Echo (FSE) 2D and 3D IR-GRE sequences);
- Gradient echo 3D (GRE) - Several multi-Field of view sequences with up to 240
- Inversion Recovery – Spin and Gradient Echo (IR-SE, mm extended axial FOV
IR-GRE) - Echo Planar Imaging (EPI) (planned release 2014 Q2)
- Dynamic Contrast Enhancement (DCE) with 1 second - Fat-suppression with IR FSE (STIR) (planned release
temporal resolution by GRE SNAPSHOT (series of quick GRE 2014 Q2)
sequences –for kinetic studies); - Easy-to-use environment available for sequence
- Apparent Diffusion Coefficient (ADC) map creation by development 11
Diffusion Weighted Imaging (DWI) sequences;
 CT subsystem

To complement the nanoScan® SPECT’s exceptional qualities Mediso designed unique combination of low dose, high
resolution and high speed CT with real time reconstruction to further improve the throughput of the system.

The large bore size of the CT allows even larger rodents to be examined such as rabbits or small monkeys.

Advantages of the CT subsystems

Available in different configurations to further tailor the system
to the researchers needs. For detailed information please contact
your local sales representative.

- Large bore size

- Variable zoom (up to x 7.6 magnification)
- Real time CT reconstruction
- Low animal dose
- Fast speed (whole body mouse 36 sec)
- Large bore transaxial field of view (up to 12 cm)

High Resolution Reconstruction of Mouse Head 20 µm voxel size 70 kV 750 mA 720

projections, 3.5 minute scanning time

Mouse Lung CT imaging 50 µm

voxel size 50 kV 750 mA 720
projections/FOV, 4.4 minute
scanning time

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nanoScan® Family - integrated SPECT based systems

T1-Weighted MRI SPECT

Mouse Thyroid 27 MBq 99mTc

Mouse kidney excretion of 99mTc-Exendin-4 peptide c57bl6 mice using 99mTc-Exendin-4

Exendin kit radiopharmaceutical kindly provided by Prof. Wang, Peking University

300 MBq of 99mTc-HMPAO,

Ultra High Resolution Parallel
Collimator SPECT imaging
of Rhesus monkey brain
perfusion

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 Animal handling – MultiCellTM

Integrated vital function monitoring is included in the base system which consist of respiratory, cardiac and temperature
feedback during preparation and acquisition.

Continuous digital temperature control: Integrated head positioning:

by closed circuit airflow integrated into the wall of the chamber for precise and reproducible animal positioning 4D/5D
– avoiding the side effect of the open airflow (dehydration of imaging accessories: dockable connections for ECG and
the eyes, contamination by pathogens etc.) respiratory gating

Embedded anesthetic gas connection: Pathogen-free construction:

for any isoflurane system through dockable connection to the for immuno-compromised animals
mouse/rat nose cone via closed circuit tubes integrated into the
wall of the chamber
One-click connection imaging cells:
for easy and fast connection of mouse/rat imaging cells
to any of the nanoScan® scanners or to the dual bed
Release docking station

button

Automatic
attachment

anesthesia gas absorption by nose cone

inhalation through tooth bar

head positioning by ear bars

temperature control by integrated hot-air channels

respiratory gating by breath sensor

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 Available MultiCellTM imaging chambers

SPECT/MRI and SPECT/CT

Imaging chamber for 1 Mouse Imaging chamber for Rat - medium Imaging chamber for Mouse - large
Inner space: 29 x 290 mm Inner space: 52 x 400 mm Inner space: 36 x 290 mm
Outer dimensions: 33 x 460 mm Outer dimensions: 56 x 540 mm Outer dimensions: 40 x 460 mm
Up to 35 g Up to 350 g Up to 80 g

SPECT/CT
Imaging chamber for 2 Mice Imaging chamber for Rat - Large Imaging chamber for Rat - XXL
Inner space: 2 x 28 x 260 mm Inner space: 70 x 440 mm Inner space: 102 x 510 mm
Outer dimensions: 64 x 470 mm Outer dimensions: 75 x 580 mm Outer dimensions: 110 x 650 mm
Up to 2x 35 g Up to 600 g Up to 1.5 kg

Imaging chamber for 3 Mice Imaging chamber for Rabbit

Inner space: 3 x 27 x 200 mm Inner space: 150 x 600 mm
Outer dimensions: 75 x 580 mm Outer dimensions: 160 x 760 mm
Up to 3x 30 g Up to 6.5 kg

SPECT/MRI
Imaging chamber with Imaging chamber with
embedded Mouse head coil embedded Rat head coil
Inner space: 40 x 180 mm Inner space: 54 x 300 mm
Outer dimensions: 56 x 480 mm Outer dimensions: 60 x 540 mm
Up to 80 g Up to 500 g

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 Optional animal handling accessories
PrepaCell™ Preparation station
- Two docking possibilities
- Closed, temperature controlled system (up-tight container) with transparent
removable cover
- Vital monitoring functions
- Embedded anaesthetic gas connection: for any isoflurane system through
dockable connection to the mouse/rat nose cone via closed circuit tubes
integrated into the wall of the chamber
- Integrated head positioning: for ultra-precise and reproducible stereotactic
animal positioning
- Fully compatible with all nanoScan® Family systems

Mediso Gating Package (Respiratory/ECG)

Respiratory and ECG cycles are monitored in real-time to synchronize image acquisition eliminating image blur caused by
respiratory and/or cardiac motion.

ECG trigger module:

- Trigger detection: threshold

- Exclusion of abnormal cardiac cycles based on histogram of R-R interval
- Number of time bins (phases) within a cardiac cycle: up to 16

Respiratory trigger module

- Trigger detection: threshold

- Exclusion of abnormal cardiac cycles based on histogram

Additional gating signals:

- 2 independent TTL input channel for external triggering

MultiCell™ adapter for third party imaging systems

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Customized adapter is available for third party imaging systems including high field MRI (up to 11T)
Operating hardware & room layout

Acquisition room Researcher’s room

nanoScan® SPECT/MRI Electronic Cabinet Acquisition workstation Post-Processing workstation

Room requirements
- Minimum room size: 12 m2
- Weight: 1880 / 830 kg
- Size (W x D x H): 1136 x 2177 x 1550 mm / 1345 x 1757 x 1678 mm
- No additional RF shielding required
- Single phase operation 115 / 230 V
- Power consumption 2300 W / 1700 W
- No cryogen or water cooling required
- Ordinary air conditioning is sufficient
- Ethernet connection for remote servicing

(parameretrs refer to SPECT/MRI and SPECT/CT respectively)

Rack
Only for MRI based systems

nanoScan® SPECT/MRI or SPECT/CT

optional
3000 mm

Acquisition/processing workstation
17
4000 mm
 Software solutions
Nucline™ all modality acquisition software
Nucline™ is an easy to use and intuitive interface for high throughput workflow across all the nanoScan® Family systems -
there is no need to learn different software solutions. In a 21CFR Part 11 compliant data management environment predefined
and customizable acquisition protocols makes the experiments daily routine.

The integrated gantry with common coordinates gives the opportunity to seamlessly co-register images and allowing for
accurate image quantification. Furthermore list mode data collection provides wide range of flexibility in data analysis
according to the requirements of the experiment.

Acquistion Room Researcher’s room

Multimodality Acquistion and Multimodality Post-Reconstruction
Processing Workstation and Post-Processing Workstation

Nucline™ PC InterView™ PC
Windows-based system, user interface for: Windows-based system, user interface for:
-- Controlling the acquistions and gantry -- SPECT and CT Post-Reconstruction
Max. 50 m
movements -- Image Post-Processing
-- SPECT and CT Post-Reconstruction -- Dicom server
-- Image Post-Processing

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Post-processing by InterView™ FUSION software
InterView™ FUSION is a multi-modal application,
developed by Mediso, is an essential part of
system. The application provides a wide range of
functionalities to evaluate PET, SPECT, CT and MRI
preclinical data. 2D single, orthogonal and tiled,
as well as 3D MIP and Volume Rendering viewers
represents fast and flexible visualization techniques
built on GPU acceleration. Viewers provide dual,
triple and quadruple fusion to accurately compare
and enhance multi-modal single and follow-up
studies. Dynamic SPECT images together with CT can
be fused, and SPECT images can be studied over time

Image processing and

quantification by VivoQuant™
software
VivoQuant™ is an image viewing, processing and
analysis software suite from inviCRO, LLC. VivoQuant™
supports data from both nuclear medicine and
magnetic resonance imaging systems and supports
advanced co-registration, viewing, processing and
quantification of data with plug-in modules dedicated
to neurology and oncology applications address the
challenging bottlenecks imaging laboratories face in
day-to-day operations.

Image analysis and kinetic modeling by PMOD

Pharmacokinetic analysis is an essential task of SPECT
imaging. Translational research and neuroscience rely
more and more on non-invasive, in-vivo measurements
of pharmacokinetic parameters. PMOD modeling
tool gives an easy and intuitive access to the wealth
of developed methods to any nanoScan® user. Blood
and time-activity data of tissue regions can easily
be imported into the modeling tool. More than 40
model configurations are available to be fitted to the
data. All results can readily be exported for statistical
analysis.

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Conformance Statement
Quality management system operated by Mediso complies with Council Directive 93/42/EEC Annex II.
Product design, development, production and services comply with EN ISO 13485 and EN ISO 14971.
Safety labels are attached to appropriate places on equipment and appear in all operation manuals.
The supplied software complies with DICOM standard.
The technical information provided here is not a detailed specification.
For details and up to date information please contact your local distributor or Mediso.

Trademarks:
nanoScan® is registered trademark of MEDISO.
NuclineTM, InterViewTM FUSION, Tera-TomoTM 3D PET, MultiCellTM, PrepaCellTM are trademarks of MEDISO.
Powered by the ASPECT IMAGING M2™ Compact MRI Technology (trademark of Aspect Imaging)
coreTM i7 is trademark of Intel.
Windows® is registered trademark of Microsoft.
VivoQuantTM is registered trade mark of InviCRO LLC.
CUDATM is trademark of NVIDIA.
This product was partially established by the support of the National Development Agency of Hungary using funds of the Research
and Technology Fund (code: TeraTomo).

MEDISO Medical Imaging Systems MEDISO USA

E-mail: [email protected] E-mail: [email protected]
Web: www.mediso.com Web: www.medisousa.com

MEDISO GmbH MEDISO Pacific PTY LTD.

E-mail: [email protected] E-mail: [email protected]
Web: www.mediso.de Web: www.medisopacific.com

MEDISO Polska Sp. z o.o

E-mail: [email protected]
Web: www.mediso.pl

MEDISO reserves the right to change data without notice © MEDISO 2016. Printed in Hungary NSCSM 08/16