Partial Mole or Complete Mole: Pathophysiology of Molar Pregnancy

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PATHOPHYSIOLOGY OF MOLAR PREGNANCY

Partial mole or complete Low intake of proteins and vitamin A, Asian heritage,
s Women older than 35 years/ younger than 25years,
mole
blood type-A married to blood type-O

Rhogam
Chronic villi degenerates and become filled with fluid

Prophylactic
No vasculature in chorionic villi course

Suction
Early death & absorption of embryo Absence of FHT curettage
or D & C

Uterus expands faster


Trophoblastic proliferation Abdominal pain
than normal

High secretion of hCG High progesterone low estrogen High chorionic thyrotropin

Marked nausea & Decreased contraction Hyperthyroidism


Amenorrhea
vomiting

medroxyprogesterone Enlarged thyroid


Multiple theca lutein Separation of vesicles from
cysts in the ovaries uterine wall gland; tachycardia

LEGEND
Vaginal bleeding &
Ovarian pain Fluid replacement Management
discharge of vesicles
Mechanism
analgesics methyldopa and labetalol
Signs and
symptoms
Risk Factors
Pallor Preeclampsia

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