Distal Humeral Fractures-Current Concepts PDF
Distal Humeral Fractures-Current Concepts PDF
Distal Humeral Fractures-Current Concepts PDF
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The Open Orthopaedics Journal, 2017, 11, (Suppl-8, M3) 1353-1363 1353
DOI: 10.2174/1874325001711011353
REVIEW ARTICLE
Distal Humeral Fractures-Current Concepts
James C. Beazley, Njalalle Baraza*, Robert Jordan and Chetan S. Modi
University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, CV2 2DX, Coventry, UK
Received: March 25, 2017 Revised: July 17, 2017 Accepted: July 18, 2017
Abstract:
Background:
Distal humerus fractures constitute 2% of all fractures in the adult population. Although historically, these injuries have been treated
non-operatively, advances in implant design and surgical technique have led to improved outcomes following operative fixation.
Methods:
A literature search was performed and the authors’ personal experiences are reported.
Results:
This review has discussed the anatomy, classifications, treatment options and surgical techniques in relation to the management of
distal humeral fractures. In addition, we have discussed controversial areas including the choice of surgical approach, plate
orientation, transposition of the ulnar nerve and the role of elbow arthroplasty.
Conclusion:
Distal humeral fractures are complex injuries that require a careful planned approach, when considering surgical fixation, to restore
anatomy and achieve good functional outcomes.
Keywords: Distal humerus fracture, Fracture fixation, Open reduction internal fixation, Total elbow arthroplasty, Anatomy, Elbow.
1. INTRODUCTION
Distal humerus fractures constitute 2% of all fractures in the adult population [1]. The injuries are distributed in a
bi-modal fashion with the first peak being seen in the young resulting from high-energy trauma and the second peak
being seen in the elderly osteoporotic population [2]. Although relatively rare, the incidence of these fractures is rising
as Pavlanen et al. reported a 5 fold increase in distal humerus fractures between 1970 and 1998 [3]. Treatment is aimed
at restoring a functional elbow, which Morrey described as requiring 30 to 130 degree range of motion [4]. Loss of this
movement can severely affect activities of daily living and lead to a loss of independence in the elderly population [5].
Treatment of these injuries is challenging due to fracture comminution, poor bone quality and difficulty in restoring the
complex anatomy of the distal humerus.
Historically, these injuries have been treated non-operatively although most studies report this management to be
associated with significant functional impairment [2]. Evolution in implant design and surgical technique has led to
improved outcomes in operatively treated patients and has resulted in fixation being the current standard of care.
Operative fixation has been shown to give satisfactory results with long term follow up demonstrating good or excellent
outcome in 86% [6, 7]. In an elderly population, internal fixation has been reported to result in better function than
those managed non-operatively [8]. The goals of surgical treatment are to restore articular congruity and bone alignment
*
Address correspondence to this author at the Department of Trauma and Orthopaedics, University Hospitals Coventry and Warwickshire NHS Trust,
Clifford Bridge Road, CV2 2DX, Coventry, UK, Tel: 02476965094; E-mail [email protected]
whilst providing rigid, stable fixation that enables early active motion [9, 10]. Currently controversy exists over several
issues of operative management including the optimal surgical approach, plate orientation, management of the ulnar
nerve and the role of elbow arthroplasty. This review will cover the anatomy and classification of distal humerus
fractures, investigations and the treatment options for distal humerus fractures including discussion surrounding these
controversial areas.
Fig. (1). Distal humerus triangle. Triangle formed by medial column (red), lateral column (blue) and articular surface (green).
4. NON-OPERATIVE TREATMENT
Non-operative treatment involves temporary splintage for pain relief followed by gentle mobilisation. This approach
has been associated with poor outcomes. Nauth et al. demonstrated that in elderly patients, those treated non-operatively
were almost three times more likely to have an unacceptable result than those treated operatively (RR=2.8 95% CI
1.78-4.4) [13]. Non-operative management is consequently reserved for undisplaced fractures and for patients with
dementia or those unable to tolerate anaesthesia. Recently Aitken et al. reported that non-operative treatment could give
a modest functional result in low demand patients whilst avoiding the substantial surgical risks [14].
Distal Humeral Fractures The Open Orthopaedics Journal, 2017, Volume 11 1355
required to reconstruct articular fragments. Two plates are utilised with the less comminuted column selected first and
secured with a pre-contoured locking plate before the second column is then fixed with a further pre-contoured plate.
Different length plates are chosen to avoid a stress riser at the end of the plates and risk of a peri-prosthetic fracture. An
example case of operative fixation is demonstrated in Figs. (2 and 3). At our centre typical post-operative management
protocol includes; a back slab for one to two weeks to protect the wound, passive mobilisation from two weeks then
active after six weeks.
Table 1. Technical objectives described O’Driscoll [11].
Sr.No Objective
1 Every screw should pass through a plate
2 Each screw should engage a fragment on the opposite side that is also fixed to a plate.
3 As many screws as possible should be placed in the distal fragments.
4 Each screw should be as long as possible.
5 Each screw should engage as many articular fragments as possible.
The screws should lock together by interdigitation within the distal fragment, thereby creating a fixed-angle architecture that provides
6
stability to the entire distal humerus.
7 Plates should be applied such that compression is achieved at the supracondylar level for both columns.
8 Plates used must be strong enough and stiff enough to resist breaking or bending before union occurs at the supracondylar level.
Despite the evolution of surgical techniques, operative fixation has been associated with dissatisfaction in 15% of
patients and complication rates of up to 35% [27, 28]. Known factors that affect outcome include fracture comminution,
reduction accuracy, fixation stability and quality of postoperative rehabilitation [29]. Complications can include
hardware failure, fracture, non-union, malunion, heterotopic ossification, elbow stiffness and ulnar neuropathy [30 -
33]. An example of a peri-prosthetic fracture is illustrated in Fig. (4).
Fig. (4). Example of peri-prosthetic fracture following a mechanical fall one year after fixation of distal humerus.
The incidence of heterotopic ossification (HO) following fixation of distal humerus fractures varies widely and is
reported to be between 0 and 21% [34]. Risk factors for HO include head injury, delay in operative intervention, and
surgery prior to definitive fixation. To date there is no level 1 evidence examining the role of HO prophylaxis in the
management of distal humerus fractures treated with ORIF. Nauth et al. pooled the results of 6 studies examining the
incidence of HO in 259 patients undergoing fixation of distal humeral fractures utilising modern fixation techniques and
not treated with HO prophylaxis [13]. They found an 8.6% rate of symptomatic HO. Two recent case series have both
reported HO rates of 3% in 67 patients with distal humerus fractures treated with HO prophylaxis, but did report a non-
union rate of 6% [22, 35]. At our institution we do not routinely give HO prophylaxis unless risk factors are present.
Three-quarters of malunion or non-union cases are caused by inadequate initial fracture fixation suggesting that
optimal stable fixation is difficult to achieve [36]. Elderly patients are particular at risk of fixation failure [37, 38] and
John et al. reported 26% of over 80 year old’s were dissatisfied with the outcome following surgery [39]. This has led to
the introduction of total elbow arthroplasty in certain patients but this remains a controversial area.
6. ELBOW ARTHROPLASTY
Total elbow arthroplasty (TEA) is becoming recognised as a safe and effective alternative to operative fixation in
the treatment of comminuted intra-articular distal humerus fractures in the elderly patient [22]. This is reflected in the
number of TEAs performed annually for distal humeral fractures, which has increased 2.6 fold between 2002 to 2012
[34]. An example of a case managed with TEA is illustrated in Figs. (5 and 6). TEA has limited longevity due to aseptic
loosening, an example of which is illustrated in Fig. (7), therefore TEA is only recommended in patients with sedentary
lifestyles [40] who can comply with the post-operative rehabilitation regime [22]. TEA patients will have lifelong
restrictions placed upon them with limited weight bearing to decrease risk of premature wear or subsequent revision
[41]. Prasad et al. [42] analysed the survival of TEA in fracture patients and showed that only 53% had implant survival
of more than 10 years and 89.5% of patients demonstrated loosening of their prostheses at this stage.
1358 The Open Orthopaedics Journal, 2017, Volume 11 Beazley et al.
Fig. (5). Comminuted distal humerus fracture (AO type C3) in an elderly patient undergoing TEA.
Fig. (6). Comminuted distal humerus fracture (AO type C3) in an elderly patient undergoing TEA.
McKee et al. compared operative fixation with TEA in a prospective, randomized, multicenter study for 40 patients
presenting with comminuted, displaced, intra-articular fractures of the distal humerus (OTA/AO type C) in patients over
the age of 65 years [33]. The study reported better Mayo Elbow Performance Score in the total elbow arthroplasty
group at 6 months (86 vs 68, P = .003), 12 months (88 vs 72, P = .007), and 2 years (86 vs 73, P = .015). A significant
difference favoring DASH score was reported at 6 months but at no further time point. Additionally there was a 25%
rate of intra-operative conversion to TEA in the ORIF group because of extensive comminution and an inability to
achieve stable fixation. Reoperation rates for TEA (3/25 [12%]) and ORIF (4/15 [27%]) were not statistically different
(P = 0.2). The authors concluded that TEA is a preferred alternative to fixation in elderly patients with complex distal
humeral fractures that are not amenable to stable fixation [33]. In a recent systematic review comparing TEA to ORIF
for the treatment of distal humeral fractures in the elderly, Githens et. al. pooled the results of 27 papers including 563
patients and found no significant difference between groups with respect to functional outcome or complications rates
[41]. Currently this area and the treatment of choice for these patients remain unclear.
Hemiarthroplasty is an alternative option and has the theoretical advantage of reducing the polyethylene wear and
being a more durable implant [43, 44]. However for implantation the patient must have an intact or reconstructable
radial head, coronoid, medial and lateral columns and functional collateral ligaments [45]. The implant requires fewer
restrictions on the patients’ activities and so may be a feasible option for slightly younger patients. Good outcomes have
been demonstrated in small case series with medium term follow up [45, 46], although reported complication rates are
comparable to that of TEA [42].
7. ULNAR NERVE
The ulnar nerve should be identified and protected throughout the surgical procedure. Controversy surrounds the
benefit of routine ulna nerve transposition following fixation; transposition theoretically lets the ulnar nerve lie in a
fresh bed but given the need to dissect further the nerve may become devascularised [47]. Chen et al. performed a
retrospective review analysing the results of 89 patients undergoing ORIF for distal humerus fractures who underwent
either a decompression alone or combined with transposition. The authors reported a significantly increased rate of ulna
neuritis post-operatively in the transposition group vs. the non-transposition group (33% vs 9% p = 0.0003) and
concluded there was no clear benefit to ulna nerve transposition [48]. For patient with pre-operative ulnar nerve
symptoms then transposition has been reported to improve recovery of symptoms (p <0.05) [49]. At our institution we
do not routinely transpose the nerve unless significant subluxation of the nerve exists on flexion following
reconstruction.
54]. The fracture is fixed with anterior to posterior headless variable pitch screws; these implants have been shown to be
superior to either Kirschner wires or cancellous screws [62]. In the presence of metaphyseal comminution, a lateral
plate may be applied. The LCL is then repaired if incompetent. Patients are placed in a back slab for two weeks to
protect the wound and are then fully mobilised.
CONCLUSION
Distal humerus fractures are a challenging but rewarding group of injuries to manage. Advances in plate design and
surgical technique have improved the outcome for patients undergoing internal fixation, which is the current standard
treatment. However the procedure can be challenging and has a high rate of complications. Total elbow arthroplasty has
been advocated as a treatment option especially for elderly patients or those with unreconstructable distal humerus
fractures.
CONFLICT OF INTEREST
The authors declare no conflict of interest, financial or otherwise.
ACKNOWLEDGEMENTS
Declared none.
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