OUR LADY OF FATIMA UNIVERSITY NAME: YANO, YOKO MAE D.

SECTION: 1S GROUP # 3
College of Nursing COURSE: BSN 3Y1-1S DATE: 02/10/2020
SCHEDULE: THURS,FRI,SAT (7-10 AM)

DRUG STUDY Diagnosis: PERICARDITS Patient’s Initials: M.J

DRUG TO DRUG NURSING

MEDICATION ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS
INTERACTION CONSIDERATION

Generic Name Pharmacodynamics  Documented BCG vaccine live -

Antiarrhythmic action: It is used to treat: hypersentivity; ceftriaxone decreases  Induration after IM  10-g pharmacy bulk
Ceftriaxone Digoxin-induced heart-  Acute bacterial hyperbilirubinemic effects of BCG vaccine live injection package should not be
rate slowing in patients Otitis media neonates, particularly those by pharmacodyamic  Eosinophilia used for direct infusion.
without heart failure is  Intra-abdominal who are premature; antagonism.  Thrombocytosis
negligible and stems infections neonates <28days if they  Diarrhea  Immune-mediated
Brand Name mainly from vagal  Pelvic receive calcium-containing Calcium acetate - do not  Elevated hepatic hemolytic anemia
(cholinergic) and Inflammatory IV products. use ANY calcium transaminases reported; if patient

MCALIM2020
Rocephin sympatholytic effects on Disease  Intravenous administration containing solutions in  Leukopenia develops anemia while
the SA node; however,  Prosthetic joint of ceftriaxone solutions combination with IV  Rash on ceftriaxone, stop
Classification with toxic doses, heart- Infection containing lidocaine ceftriaxone; risk of  Increased blood urea antibiotic until etiology
rate slowing results from  Meningitis  Lidocaine contraindications potentially fatal particulate nitrogen (BUN) determined; severe
Cephalosporins direct depression of SA  Acute if lidocaine solution used as precipitation in lungs,  Induration at IV site hemolytic anemia,
node automaticity. uncomplicated solvent with ceftriaxone for kidneys. Separate  Pain including fatalities,
pyelonephritis intramuscular injection. administration by at least reported in both adults
Inotropic action: The  Uncomplicated 48hrs. and children.
Dosage & Frequency effect of digoxin on the gonococcal
myocardium is dose infections Calcium carbonate - do  May increase INR,
1g IV q12h related and involves both  Skin and soft not use ANY calcium especially in
direct and indirect necrotizing containing solutions in nutritionally deficient
mechanisms infection combination with IV patients, hepatic or
 Severe acute ceftriaxone; risk of renal disease or
Pharmacokinetics bacterial potentially fatal particulate prolonged treatment.
Stock Dose Absorption: With tablet rhinosinusitis precipitation in lungs,
or elixir, 60% to 85% of kidneys. Separate  Dosage must be
1 to 2g IV qd dose is absorbed. With administration by at least adjusted in severe renal
capsule form, 48hrs. insufficiency
bioavailability increases
Calcium Chloride -  Superinfections and
Distribution: Distributed contraindicated in neonates promotion of
widely in body tissues. if they require treatment nonsusceptible
Highest levels occur in the with calcium containing IV organisms may occur
heart, kidneys, intestine, solutions, including with prolonged use or
stomach, liver, and continous calcium repeated therapy.
skeletal muscle; lowest containing infusions such
levels are in the plasma as parenteral nutrition  Use with caution in
and brain. Digoxin crosses because of the risk of patients with history of
both the blood-brain precipitation of ceftriaxone GI disease, especially
barrier and the placental and calcium. colitis.
barrier; fetal and maternal.
Calcium citrate - do not  Use with caution in
Metabolism: In most use ANY calcium breast-feeding women;
patients, a small amount of containing solutions in drug may displace
digoxin apparently is combination with IV bilirubin from albumin-
metabolized in the liver ceftriaxone; risk of binding sites,
and gut by bacteria. potentially fatal particulate increasing risk of
precipitation in lungs, kernicterus.
kidneys. Separate
Excretion: Most of dose administration by at least  Abnormal gallbladder
is excreted by the kidneys 48hrs. sonograms reported,
as unchanged drug. possibly the result of

MCALIM2020
Calcium gluconate - do ceftriaxone-calcium
not use ANY calcium precipitates;
containing solutions in discontinue if signs or
combination with IV symptoms of
ceftriaxone; risk of gallbladder disease
potentially fatal particulate occur.
precipitation in lungs,
kidneys. Separate  Use with caution in
administration by at least patients with history of
48hrs. GI disease.

Typhoid vaccine live -

ceftriaxone decreases
effects of typhoid vaccine
live by pharmacodynamic
antagonism.

MCALIM2020