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    Sin A Rest Syrup Tablets

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    ryblackhawk
    SINAREST is a combination drug containing paracetamol, pseudoephedrine, chlorpheniramine, caffeine (in tablets), sodium citrate and menthol (in syrup) for relief of nasal congestion, allergic symptoms, sinus pain and headache. It is available as tablets, syrup and drops. The tablets contain paracetamol, pseudoephedrine, chlorpheniramine and caffeine. The syrup contains paracetamol, pseudoephedrine, chlorpheniramine, sodium citrate and menthol. The drops contain paracetamol, pseudoephedrine and chlorpheniramine. It is generally well tolerated but some individuals may experience side effects like tachycardia, pal

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    Sin A Rest Syrup Tablets

    Uploaded by

    ryblackhawk
    101 views3 pages
    SINAREST is a combination drug containing paracetamol, pseudoephedrine, chlorpheniramine, caffeine (in tablets), sodium citrate and menthol (in syrup) for relief of nasal congestion, allergic symptoms, sinus pain and headache. It is available as tablets, syrup and drops. The tablets contain paracetamol, pseudoephedrine, chlorpheniramine and caffeine. The syrup contains paracetamol, pseudoephedrine, chlorpheniramine, sodium citrate and menthol. The drops contain paracetamol, pseudoephedrine and chlorpheniramine. It is generally well tolerated but some individuals may experience side effects like tachycardia, pal

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    Sin a Rest Syrup Tablets

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    SINAREST is a combination drug containing paracetamol, pseudoephedrine, chlorpheniramine, caffeine (in tablets), sodium citrate and menthol (in syrup) for relief of nasal congestion, allergic symptoms, sinus pain and headache. It is available as tablets, syrup and drops. The tablets contain paracetamol, pseudoephedrine, chlorpheniramine and caffeine. The syrup contains paracetamol, pseudoephedrine, chlorpheniramine, sodium citrate and menthol. The drops contain paracetamol, pseudoephedrine and chlorpheniramine. It is generally well tolerated but some individuals may experience side effects like tachycardia, pal

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    101 views3 pages

    Sin A Rest Syrup Tablets

    Uploaded by

    ryblackhawk
    SINAREST is a combination drug containing paracetamol, pseudoephedrine, chlorpheniramine, caffeine (in tablets), sodium citrate and menthol (in syrup) for relief of nasal congestion, allergic symptoms, sinus pain and headache. It is available as tablets, syrup and drops. The tablets contain paracetamol, pseudoephedrine, chlorpheniramine and caffeine. The syrup contains paracetamol, pseudoephedrine, chlorpheniramine, sodium citrate and menthol. The drops contain paracetamol, pseudoephedrine and chlorpheniramine. It is generally well tolerated but some individuals may experience side effects like tachycardia, pal

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    SINAREST

    Composition
    Each SINAREST Tablet contains:
    Paracetamol 500 mg
    Pseudoephedrine hydrochloride 60 mg
    Chlorpheniramine maleate 2 mg
    Caffeine (anhydrous) 30 mg

    Each 5 ml of SINAREST Syrup contains:


    Paracetamol 125 mg
    Pseudoephedrine hydrochloride 30 mg
    Chlorpheniramine maleate 2 mg
    Sodium Citrate 60 mg
    Menthol 1 mg

    Each ml of SINAREST Drops contains:


    Paracetamol 125 mg
    Pseudoephedrine hydrochloride 15 mg
    Chlorpheniramine maleate 1 mg

    Pharmacology
    SINAREST contains a clinically proven analgesic-antipyretic Paracetamol with
    decongestant Pseudoephedrine and an antihistamine Chlorpheniramine.
    Paracetamol produces analgesia by elevation of the pain threshold and
    antipyretic effect through action on the hypothalamic heat-regulating center.
    Paracetamol is equal to aspirin in analgesic and antipyretic effectiveness, and it
    is unlikely to produce many of the side effects associated with aspirin and
    aspirin-containing products.

    Chlorpheniramine in SINAREST provides prompt relief of itchy-watery eyes,


    runny nose, sneezing, itching of the nose or throat due to respiratory allergies.

    SINAREST contains, in addition to the above ingredients, a decongestant,


    Pseudoephedrine, which is a sympathomimetic amine. It provides prompt relief
    of nasal and sinus congestion.

    Caffeine in SINAREST Tablets enhances the analgesic activity of Paracetamol


    and serves to reduce incidence of sedation due to Chlorpheniramine.

    The Sodium citrate in SINAREST Syrup liquefies mucus and helps


    expectoration whereas Menthol has a cooling and soothing effect.

    The pharmacokinetics of this combination is well matched and synergetic. All the
    drugs are well absorbed orally.
    Indications
    SINAREST is indicated for:
     Relief of nasal and sinus congestion.
     Relief of allergic symptoms of the nose or throat due to upper respiratory
    tract allergies.
     Relief of sinus pain and headache.
     Adjunct with antibacterials in sinusitis, tonsillitis and otitis media.
     Post-operative after tonsillectomy.

    Contraindications
    The use of SINAREST is contraindicated in patients with hypersensitivity to any
    of the ingredients of the formulation.

    SINAREST is contraindicated in patients with severe hypertension.

    Precautions
    In case a hypersensitivity reaction occurs which is rare, SINAREST should be
    discontinued.

    SINAREST contains Paracetamol therefore should not be used in conjunction


    with other Paracetamol containing products.

    SINAREST should be used with caution in patients with renal or hepatic


    dysfunction, diabetes mellitus, hyperthyroidism, cardiovascular problems,
    epilepsy and closed angle glaucoma.

    It is advisable not to drive or operate machinery when on treatment with


    SINAREST.

    Drug Interactions
    Clinically significant drug interactions may occur on concomitant administration
    of SINAREST with monoamine oxidase inhibitors, tricyclic antidepressants, -
    adrenergic agents, methyldopa, reserpine and veratrum alkaloids.

    Adverse Reactions
    SINAREST is generally well tolerated and adverse events are rare.
    Hypersensitive individuals may display ephedrine-like reactions such as
    tachycardia, palpitations, headache, dizziness and nausea. Use of
    sympathomimetics has been associated with fear, anxiety, restlessness, tremor,
    weakness, dysuria, insomnia, hallucinations and convulsions. Chlorpheniramine
    in SINAREST may cause sedation.
    Dosage & Administration
    The usual recommended dose of SINAREST Tablets in adults is 1-2 tablets tid
    or qid.

    The usual recommended dose of SINAREST Syrup in children is 1-2


    teaspoonful (5-10 ml) tid or qid.

    The usual recommended dose of SINAREST Drops in infants is as follows:


    1-6 months : 0.2 ml tid or qid.
    7-12 months : 0.2-0.4 ml tid or qid.
    1-2 years : 0.4-0.8 ml tid or qid.

    Presentation
    SINAREST Tablet is available in a blister of 10 tablets.
    SINAREST Syrup is available in bottles of 60 ml and 100 ml with a measuring
    cup.
    SINAREST Drops is available in a bottle of 15 ml with a calibrated dropper.

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