Course of Illness:: Classification

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DENGUE FEVER

• An acute febrile mosquito-borne tropical disease caused by the


dengue virus.
• Vector: female Aedes Aegypti.
EPIDEMIOLOGY:
 Case of dengue in the Philippines as of 2012: 80,742. (DOH)
Pathophysiology:

Classification:

Course of illness:

Classification:
 History/PE
o Take note the date of onset of fever/illness.
o Warning signs
o Mental status
o Tourniquet test
 Laboratory:
o CBC
o UA
o AST, ALT
o Chest x ray
o If with bleeding: PT, APTT.

Management:
Dengue Fever without Danger Signs

General measures:
-Bed Rest
-Suficient fluid intake
-Paracetamol as needed

o Patient with stable hematocrit can be sent home, advise for


return to hospital of with development of warning sign.
o Monitor regularly for signs of progressing disease, improving WBC
count, deverference, warning signs until out of critical phase

Dengue Fever with Danger Signs

Adequate hydration:

o Encourage OFI if tolerated


o If not, start IVF
o Initial 5-7 ml/kg/hr for 1-2 hours
o Reduce to 3-5 ml/kh/hr for 2-4 hrs
o Reduce further to 2-3 ml/kg/hr or less based on clinical
response.

 If HCT remains the same or rises minimally, continue with 2-3


Course of illness: ml/kg/hr for another 2-4 hours

LLOYD F. ALIAS
#Matatag 2016
 If worsening of vitals and rapidly rising Hct, increase rate to 5-10
ml/kg/hr, for 1-2 hrs

 Reduce IVF gradually until adequate UO and/or fluid intake or Hct


decreases below baseline.
DIFFRENTIAL DIAGNOSIS
Monitoring:
• Malaria - Malaria is caused by a parasite that is passed from one
o Baseline Hct then every 6-12 hrs human to another by the bite of infected Anopheles mosquitoes.
o Serum glucose and other tests for organ function
Points to support Points to against
Severe Dengue
 Endemic in the  Remittent fever
o Initial resuscitation: crystalloids at 5-10 ml.kg.hr for 1 hour Region  No Chills
o If with improvement: May reduce IVF to 5-7 ml/kg/hr for 1-2  Fever  No seizures
 Headaches
hours, 3-5 ml/kg/hr for 2-4 hrs and then reduced further
 Nausea and vomiting
depending on hemodynamic status. IVF maintained over 24 to 48
 Body weakness
hours.
o If unstable: Recheck Hct after initial IV bolus
o If Hct still high(>50 %), give a second bolus of crystalloid solution
or 10-20 ml/kg/hr for 1 hour (if with improvement, reduce rate to • Typhoid Fever - also known as enteric fever, is a potentially fatal
7-10 ml/kg/hr) multisystemic illness caused primarily by Salmonella enterica.
o If Hct decreases, may indicate bleeding and need to crossmatch
and tranfuse blood. Points to support Points to against

Management of Hypotensive Shock:  Fever  (-) Rose spots


 Headache  Remittent fever
o Resuscutation with crystalloid or colloid at 20 ml/kg bolus for 15  Malaise  (-) Diarrhea
minutes  Abdominal pain and  (-)
o If(+) improvement, give IVF: 10 ml/kg/hr for 1 hours then reduce tenderness Hematochezia
gradually  Thrombocytopenia
o If still unstable: check Hct, assess need for further fluid
resuscitationn.
• Letospirosis - Leptospirosis is a disease caused by bacteria
PROGNOSIS:
(Leptospira interrogans) that produce a wide range of symptoms
• Death has occurred in 40–50% of patients with shock, but with
adequate intensive care deaths should occur in <1% of cases Points to support Points to against

CRITERIA FOR DISCHARGING INPATIENTS • Fever


• Head ached
• Absence of fever for at least 3 days without use of antipyretics or • Body weakness
Cryotherapy • Loss of appetite
• Return of appetite • Abdominal pain
• Visible clinical improvement • Vomiting
• Good urine output •
• Stable hematocrit •
• No respiratory distress from pleural effusion or ascites
• Platelet count of more than 100,000 per mm3

PREVENTION

DOH program: 4S

o Search and destroy


o Seek early consultation
o Self protection
o Say no to indiscriminate fogging

IMMUNIZATION

LLOYD F. ALIAS
#Matatag 2016

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