Soal Seleksi Impsq Tahap 1

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SOAL SELEKSI IMPSQ TAHAP 1 (SANJAYA HALIM)

Renal

1. Inulin has the highest renal clearance (F)


2. Hypoparathyroidism causes a decrease in renal ca2+ clearance (F)
3. Spironolactone will be decreased k+ secretion in the distal tubule (T)
4. Increased filtraction fraction would increase the reabsorbtion of isoosmotic fluid in the
proximal tubule (T)
5. TBW is composed of 60% in obese person, while ICF is 40% and ECF is 20% (F)
6. 25 (OH)2D are converted into 1,25 (OH)2D in mesangial cell of the nephron and are
metabolite active of Vitamin D (F)
7. Atrial Natriuretic Protein (ANP), causes vasodilatation of afferents arteriole, and
vasoconstriction of efferent arteriole (T)
8. RBF is 25% of the cardiac output (T)
9. RBF is directly inproportional to the pressure difference between the renal artery and vein (F)
10. Infusion of isotonicl NaCl is also called isoosmotic volume expansion (T)

Cardio

1. PR interval in ecg represent of ventricular filling (T)


2. Phase 3 in cardiac action potential is also known as Plateau phase (F)
3. During phase 1 there is upstroke of action potential generated by the sudden influx of Na+ (T)
4. Capillary sistem has the highest resistance in the cardiovascular system (F)
5. Brain receive the highest ammount of cardiac output (F)
6. Negative dromotropic decrease the conduction velocity through AV Nodes (T)
7. Cardiac muscle consist of special fiber of which consist skeletal muscle profile, but can
contract involuntary (T)
8. Pre-load is end diastolic volume which is related to Right Arterial Pressure (T)
9. Second heard sound (S2) is produced by Mitral Valve (F)
10. Symphatetic stimulation has a chronotropic effect on SA node, which can increase the heart
rate (T)

Respiratory

1. Tidal Volume of lung in normal health person is approximately 700ml (F)


2. Lung Vital Capacity is the sum of Tidal Volume, IRV, and ERV (T)
3. Transmural pressure is alveolar pressure minus intrapleural pressure, and maintaned negative
during inspiration (T)
4. COPD is an obstructive Lung disease, and Lung Fibrosis is a restrictive Lung disease (T)
5. COPD is characterized by decreased in lung compliance, while Lung Fibrosis is characterized
by increased in lung compliance (F)
6. N2O transport is perfusion limited, and CO transport is diffusion limited (T)
7. Transport of O2 during normal condition is diffusion limited (F)
8. Increased in 2,3 DPG will cause a shift to the left in Hemoglobin-O2 dissociation curve (F)
9. Ventilation is higher at the apex of the lung (F)
10. Inspiration impulse is generated by Ventral Respiratory Group in the Reticular Formation (F)

Repro

1. 5a Reductase inhibitors can block the activation of testosterone into DHT, which can be used
as a therapy for Benign Prostatic Hyperplasia (BPH) (T)
2. LH surge is responsible for the ovulation during the Luteal Phase (F)
3. 17B-Estradiol is the estrogen produced by Theca Cells (F)
4. Differentiation of penis, scrotum and prostate is the results of Testosterone in the peripheral
tissue (F)
5. Morning Sickness during the first trimester of pregnancy is a side effect of HCG (T)
6. The major placental estrogen is estriol (T)
7. During menstruation, the endometrium is sloughed because the abrupt withdrawal of estrogen
and progesterone (T)
8. Day 0-14 in menstrual cycle is also known as Luteal Phase (F)
9. Male have the XY sex chromosome, which during embryonal development the testis will
secrete anti-mullerian hormone (T)
10. Menstrual cycle are controlled by only negative feedback mechanism (F)

Acid-Base

1. Na+ and H2O are mostly reabsorbed at the Distal Tubule of the Renal (F)
2. Starling forces in the peritubular capillary capillary blood flow govern how much of isosmotic
fluid will be reabsorbed (T)
3.CO2 is also known as volatile acid (T)
4. Phospate is major extracellular buffer (F)
5. HCO3 is major extracellular buffer (T)
6. Kussmaul breathing (Hyperventilation) is a respiratory compensation for metabolic acidosis
(T)
7. The normal value of serum anion gap is 20 mEq/L (F)
8. Vomiting is one of the cause of metabolic alkalosis (T)
9. Diarrhea can cause GI loss of HCO3, which can lead to metabolic acidosis (T)
10. High altitude can stimulate medulla respiratory center, which can lead to respiratory alkalosis
(T)

ESSAY

1. Is there a proportionate relationship between heart rate and cardiac output?

(At high tachycardia, the decreased diastolic filling time tends to reduce stroke volume, and so
the cardiac output does not increase linearly with increase in frequency of heart beat.)

2. What is the physiological benefit of the response of the pulmonary blood vessels to local
hypoxia?
(Hypoxic pulmonary vasoconstriction helps to compensate for V/Q mismatching.)

3. How is the differential tubular reabsorption of sodium along the nephron linked to renal
control of water balance?

(The proximal tubule reabsorbs water iso-osmotically following diverse sodium-solute transport.
The reabsorption of sodium at the ascending loop of Henle contributes to the generation of
hyperosmotic interstitium, essential for water reab- sorption during negative water balance.)

4. How does arterial blood PCO2 affect the renal tubular acid secretion?

(Increased arterial PCO2 will increase tubular secretion of hydrogen ions in the kidneys.)

5. What Principal Placental Hormones Help to Ensure the Health of the Fetus and Mother?

(The placenta secretes human chorionic gonadotropin (hCG), placental growth hormones,
progesterone, estrogen and corticotrophin-releasing hormone (CRH) during gestation. The fetal
adrenal glands participate in the synthesis of the major placental estrogen, estriol.)

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