NPEP Procedure Flowchart Template
NPEP Procedure Flowchart Template
NPEP Procedure Flowchart Template
This procedure is intended to facilitate the management of incidents involving potential exposure to HIV
infection in the non-occupational context, ensuring compliance with the:
Post-Exposure Prophylaxis after Non-Occupational and Occupational exposure to HIV: Australian
National Guidelines (Second edition), (2016)
The decision to initiate (or not) non-occupational post-exposure prophylaxis (NPEP) and the
baseline procedures required are guided by the flow charts in this document. The
Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) and the
Committee for these Guidelines strongly recommend that reference also be made to the
National Guidelines before any decision to initiate NPEP in ED
www.pep.guidelines.org.au
Establish eligibility for HIV NPEP using the risk assessment flowchart
and
pp. 6-8 of the Guidelines
Prior to prescribing NPEP, consult with the ED Staff Specialist and consider consultation with the
on-call Infectious Diseases Consultant or Sexual Health Physician particularly if the patient is:
pregnant or breast feeding
has significant medical co-morbidities, in particular compromised renal function
No NPEP
Yes
prescribed?
1
HIGH RISK EXPOSURE
Condomless receptive intercourse (anal or vaginal)i
Condomless insertive intercourse (anal or vaginal) i
Use of contaminated injecting equipment
i
Condomless means no condom used or condom slippage/breakage.
Notes: Condomless receptive oral intercourse with ejaculation MAY BE CONSIDERED as a high risk exposure
providing the source is known to be HIV-positive with a detectable HIV viral load and there is oral mucosal
disease or an open lesion in the mouth or throat.
Significant exposure of non-intact skin with blood, sperm or vaginal fluids MAY ALSO BE CONSIDERED as a
high risk exposure providing the source is known to be HIV positive with a detectable HIV viral load.
3
The patient presents within 72 hours of exposure
1 + 2 + 3 = NPEP