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    Aso (Antistreptolysin O) PDF

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    Ibrahim Siddig
    This document provides information about the ASO (Antistreptolysin O) test performed by the Chemistry department. The test detects antibodies to Streptolysin O to help diagnose current or past group A streptococcal infections or rheumatic fever. Specimens are sent to Mayo Medical Laboratories for testing. The turnaround time is 1-3 days and testing is performed daily Monday through Saturday. A blood sample is collected in an SST tube and centrifuged to separate serum for testing.

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    Aso (Antistreptolysin O) PDF

    Uploaded by

    Ibrahim Siddig
    203 views3 pages
    This document provides information about the ASO (Antistreptolysin O) test performed by the Chemistry department. The test detects antibodies to Streptolysin O to help diagnose current or past group A streptococcal infections or rheumatic fever. Specimens are sent to Mayo Medical Laboratories for testing. The turnaround time is 1-3 days and testing is performed daily Monday through Saturday. A blood sample is collected in an SST tube and centrifuged to separate serum for testing.

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    This document provides information about the ASO (Antistreptolysin O) test performed by the Chemistry department. The test detects antibodies to Streptolysin O to help diagnose current or past group A streptococcal infections or rheumatic fever. Specimens are sent to Mayo Medical Laboratories for testing. The turnaround time is 1-3 days and testing is performed daily Monday through Saturday. A blood sample is collected in an SST tube and centrifuged to separate serum for testing.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    203 views3 pages

    Aso (Antistreptolysin O) PDF

    Uploaded by

    Ibrahim Siddig
    This document provides information about the ASO (Antistreptolysin O) test performed by the Chemistry department. The test detects antibodies to Streptolysin O to help diagnose current or past group A streptococcal infections or rheumatic fever. Specimens are sent to Mayo Medical Laboratories for testing. The turnaround time is 1-3 days and testing is performed daily Monday through Saturday. A blood sample is collected in an SST tube and centrifuged to separate serum for testing.

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    of 3

    Lab Dept: Chemistry

    Test Name: ASO (ANTISTEPTOLYSIN O)

    General Information

    Lab Order Codes: ASOT

    Synonyms: Antistreptolysin-O (ASO) Quantitative

    CPT Codes: 86060 – Antistreptolysin O; titer

    Test Includes: Antistreptolysin O concentration reported in IU/mL. If anti-DNase B is


    also desired, see Streptococcal Antibodies

    Logistics

    Test Indications: Antistreptolysin O (ASO) titers are used to diagnose current versus past
    infections with group A streptococci. The test detects antibodies to
    Streptolysin O, one of the many streptococcal antigens. In addition, it
    may be used to help diagnose rheumatic fever.

    Lab Testing Sections: Chemistry - Sendouts

    Referred to: Mayo Medical Laboratories (MML Test: ASO)

    Phone Numbers: MIN Lab: 612-813-6280

    STP Lab: 651-220-6550

    Test Availability: Daily, 24 hours

    Turnaround Time: 1 – 3 days, testing performed Monday-Saturday

    Special Instructions: N/A

    Specimen

    Specimen Type: Blood

    Container: SST (Gold, marble or red) tube

    Draw Volume: 3 mL (Minimum: 1.5 mL) blood

    Processed Volume: 1 mL (Minimum: 0.5 mL) serum

    Collection: Routine venipuncture


    Special Processing: Lab Staff: Centrifuge specimen, remove serum aliquot into a plastic
    sample cup. Store at refrigerated temperatures.

    Patient Preparation: Fasting is preferred, but not required.

    Sample Rejection: Mislabeled or unlabeled; specimens other than serum; gross lipemia

    Interpretive

    Reference Range: Age: Range (IU/mL):

    <5 years: Less than or equal to 70 IU/mL

    5 – 17 years: Less than or equal to 640 IU/mL

    ≥18 years: Less than or equal to 530 IU/mL

    Interpretation: Elevated values are consistent with an antecedent


    infection by group A streptococci. Although the antistreptolysin O (ASO)
    test is quite reliable, performing the anti-DNase is justified because
    ASO response is not universal and elevated ASO titers are found in the
    sera of about 85% of individuals with rheumatic fever. ASO titers remain
    normal in about 15% of individuals with the disease. The same holds
    true for other streptococcal antibody tests. A significant portion of
    individuals with normal antibody titers for 1 test will have elevated
    antibody titers for another test. Thus, the percentage of false-negatives
    can be reduced by performing 2 or more antibody tests. Skin infections,
    in contrast to throat infections, are associated with a poor ASO
    response. Patients with acute glomerulonephritis following skin infection
    (post-impetigo) have an attenuated immune response to streptolysin O.
    For such patients, performance of an alternative streptococcal antibody
    test such as anti-DNase B is recommended.

    Critical Values: N/A

    Limitations: The use of the antistreptolysin O (ASO) for the diagnosis of an acute A
    streptococcal infection is rarely indicated, unless the patient has
    received antibiotics that would render the culture negative. There are a
    certain limitations to the use of the ASO test in these circumstances due
    to the delay and attenuation of the immune response following early
    antibiotic therapy.

    False-high titers may be obtained wit sera that are contaminated by


    certain bacterial organisms during shipment or storage and n patients
    with liver disease where the presence of high lipoprotein concentrations
    in the serum may mimic antibody activity.

    Methodology: Nephelometry

    References: Mayo Medical Laboratories November 2017


    Updates: 3/24/2014: Moved from an internal test to Mayo.
    12/8/2017: Updated collection container.

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