Drug Study: Acetadote, Mucomyst Mucolytics

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DRUG STUDY

GENERIC NAME: Acetylcysteine


Brand name: Acetadote, Mucomyst
Drug Classification: Mucolytics

DOSAGE, ROUTE, SIDE EFFECTS and


FREQUENCY (prescribed and INDICATION MECHANISM OF ADVERSE REACTIONS
recommended) ACTION (by system)
Prescribed: Adjunctive therapy for CNS: fever, drowsiness
800 mg abnormal viscid or CV: chest tightness,
thickened mucus tachycardia, edema,
Available forms: secretions in patients flushing
IV injection: 200mg/ml with pneumonia, EENT: rhinorrhea,
Solution: 10%, 20% bronchitis, pharyngitis
bronchiectasis, Respiratory:
complications of bronchospasm, cough,
thoracic surgery or CV dyspnea
surgery Skin: clamminess,
diaphoresis, urticarial
Other: Anaphylactiod
reaction

NURSING RESPONSIBILITIES
CONTRAINDICATION/S (at least 10)
Contraindicated with patients • Monitor cough type and frequency
hypersensitive to drug • Ingestion of more than 150mg/kg of acetaminophen may cause
hepatotoxicity. Measure acetaminophen level 4hours after ingestion to
Use cautiously in elderly or debilitated determine risk of hepatotoxicity
patients with severe respiratory
• Obtain baseline AST, ALT, bilirubin, PT, BUN, creatinine, glucose and
insufficiency
electrolyte levels
• Facial erythema may occur within 30 minutes to 60 minutes of start of
IV infusion and usually resolves without stopping infusion
• When acetaminophen level is below toxic level according to
nomogram, stop therapy
• The vial stopper does not contain natural rubber latex, dry natural
rubber or blends of natural rubber
• Warn patient that drug may have a foul taste or smell that may be
distressing
• For maximum effect, instruct patient to cough or clear his airway
before aerosol administration
• Don’t confuse acetylcysteine with acetylcholine

Patient’s Name / Room No.

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