PSOMAT Psychotherapy With Patients With Psychosomatic Disorders

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The document discusses psychosomatic disorders from a holistic perspective, considering psychological, social, biological and other factors. It also discusses different types and etiology of psychosomatic disorders as well as therapeutic approaches.

A psychosomatic disorder refers to a condition where psychological factors affect physical health and symptoms. It does not refer to a specific discipline but a way of thinking about interactions between the mind and body in relation to health and disease.

Some examples of psychosomatic etiology discussed include psychological patterns related to thyroid disease, effects of anxiety on physiology, and influence of events at the psychological level on bodily processes like gastric motility.

Psychotherapy

with Patients with


Psychosomatic Disorders

GEORGE C. CURTIS
e-Book 2015 International Psychotherapy Institute

From The Theory and Practice of Psychotherapy With Specific Disorders by Max Hammer, Ph.D.

Copyright 1972 by Max Hammer, Ph.D.

All Rights Reserved

Created in the United States of America


Table of Contents

TYPES OF PSYCHOSOMATIC DISORDERS

PSYCHOSOMATIC ETIOLOGY

THERAPEUTIC CONSIDERATIONS

REFERENCES

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Psychotherapy with Patients with Psychosomatic Disorders

In approaching the treatment of psychosomatic disorders it is first

necessary to consider what a psychosomatic disorder is. This is by no means


simple. The expression psychosomatic does not refer to a discipline, a field

of study nor a medical subspecialty, but to a point of viewa way of thinking

about any process which involves the total human organism. This way of

thinking is synthetic and tries to apply all available information and methods
which might be useful, whether from psychodynamics, sociology,

anthropology, pathology, pharmacology, genetics, physiology, immunology,

medicine, surgery or related fields. In practice however, the elements for


synthesis vary not only with the problem under consideration but also with

the capacities and experience of the synthesizer. The term psychosomatic

has been criticized on the grounds that it implies a mind-body dichotomy


rather than unity of mind and body. In the present writers opinion, the term

and the viewpoint to which it refers are forerunners of a general systems


approach to health and disease.

One of the cardinal principles both in psychosomatics and in general

systems theory is that events within a system or level of description

psychological, social, anatomical, physiological and so forthmust be studied

by methods appropriate to that level and described in the language of that


level. Only after this has been done may events from two or more levels be

The Theory and Practice of Psychotherapy with Specific Disorders 5


correlated. Thus if we wish to study physiological changes in anxiety we
cannot use physiological data to infer the presence of anxiety; if we do, our

reasoning will be circular. If we wish to study psychodynamic patterns in

thyroid disease, we cannot use psychodynamic data to infer the presence of


thyroid disease nor medical data to infer the presence of psychodynamic

patterns. These statements may seem truisms, but their principles are

ignored with surprising frequency.

The term psychosomatic is also used in a more limited sense to refer

to a causal sequence from above downwardthat is, in which events at the

psychological-psychodynamic level appear to influence events at some lower

order of complexity, such as gastric motility or cardiovascular dynamics. This

usage is in contrast with the term somatopsychic which implies the


opposite causal sequence, such as the effect of brain damage on mental

function or psychological reactions to physical disease. Psychosomatic events

have somatopsychic feedback and vice versa, so that in a strict sense there are
no purely psychosomatic or somatopsychic sequences. Nevertheless the

distinction is convenient and necessary for ordering certain types of


observations.

When the term disorder is added to the term psychosomatic, one

ordinarily means clinical conditions in which psychosomatic causal


sequences are inferred. Some idea of the diversity of these conditions may be

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conveyed by the following classification, which should be considered as
illustrative rather than definitive.

TYPES OF PSYCHOSOMATIC DISORDERS

Somatic Complaints of a Purely Ideational Nature

These are symptoms which express ideas and do not depend on

physical changes in the areas complained of. Needless to say, the ideas may
be, and often are, unconscious.

Somatic Delusions and Hallucinations

Although the idea expressed by these symptoms is conscious, it can and


usually does stand in the place of other ideas and feelings which are not

conscious. A patient may complain that he has pain and heaviness in his chest

because his heart has turned to stone or he has nausea and indigestion
because he is rotten inside. If the patient is grossly psychotic, the nature of

the complaint is quickly recognized. If his cognitive functions are relatively


intact and he has only an isolated somatic delusion, then its true nature is

easily missed. Being aware that people may think him crazy, he consults a
general physician complaining only of chest pain or indigestion. On finding

nothing wrong, the physician reassures him that his complaint is due to

nerves, and the patient seeks elsewhere for someone to soften his heart of

The Theory and Practice of Psychotherapy with Specific Disorders 7


stone or to remove the rottenness inside. The examples chosen happen to be
ones which convey feelings of self-accusation, but this type of body

language may be used as well to express ideas related to other impulses and

feelings. This type of complaint must, of course, be distinguished from

delusional explanations erected on organically based symptoms, as for

example pains of angina pectoris1 interpreted as messages from heaven.

Obsessions About the Body

Somatic obsessions also express in body language ideas related to

unconscious wishes. However, the patient recognizes them as irrational, even

if this recognition does not bring relief of anxiety. As in the case of delusions,
the consciously expressed idea stands instead of unconscious ones.

Hypochondriasis

This term is used loosely to refer to multiple bodily complaints which


do not depend on physically based sensations. They are usually obsessional,

delusional or a mixture of the two.

Conversion Reactions (Hysteria)

Like somatic delusions and obsessions, conversion reactions also

express in body language ideas related to unconscious wishes. Instead of

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appearing in conscious thought they appear involuntarily in charade or
pantomime in which the players are organ systems. In the early days of

psychoanalysis all psychosomatic disorders were assumed to be conversion

reactions, even those with marked tissue damage; ones blood pressure,

ulcers, bleeding from the bowel, etcetera, were all assumed to be symbolic

expressions of unconscious ideas. Following World War II, there was a


widespread reaction against this view. Many students of psychosomatics then

felt that unconscious ideas could be expressed only by the sensory and

voluntary motor symptoms and that the diagnosis of conversion reaction or


hysteria should be confined to symptoms in these systems. Despite explicit

statements of this sort, a number of symptoms involving involuntary systems

continued to be recognized as hysterical, such as vomiting and false

pregnancy (including cessation of menstruation). The earlier view was never


completely supplanted, and Sperling, for example, continued to regard

ulcerative colitis as a pregenital conversion in which bleeding from the bowel


symbolizes a traumatic separation in the form of an abortion.

More recently, Engel and Engel and Schmale have marshalled


substantial evidence that the conversion mechanism may underlie a wide

variety of involuntary symptoms. They further maintain that tissue damage

may occur as a complication of conversion reactions, although the damage

itself is not the conversion reaction and does not have primary psychological
meaning. Through the process of secondary symbolization the damage may,

The Theory and Practice of Psychotherapy with Specific Disorders 9


of course, still acquire psychological meaning after it has developed.

Medical Consequences of the Patients Behavior

This is a heterogeneous group of disorders, some of which excite the


interest of psychosomatic workers and some of which do not. As a rule

interest in the damage caused by suicide attempts, hepatic cirrhosis2


following alcoholism or illnesses aggravated by heavy smoking is not

regarded as psychosomatic interest. Interest in obesity, on the other hand, is

regarded as psychosomatic interest. Most cases of obesity are caused by


eating more calories than are consumed by bodily activity. The mystery lies in

the reason for the dissociation between physiological need for food and

eating. It is generally recognized that neurotic and psychotic conflicts may


contribute to any of these behaviors, but there is no agreement as to whether

similar psychodynamic constellations underlie similar external behaviors.

Behavior which is not necessarily neurotic may also have medical

consequences, as for example, the eating of diets high in cholesterol which

seem to contribute to the development of coronary artery disease.

Psychophysiological Symptoms

In this category belong symptoms such as perspiration and pounding of


the heart in anxiety attacks, constipation and anorexia in depression, aching

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muscles and joints resulting from chronic muscular tension, spastic colon,
emotional diarrhea, upset stomach due to emotional tension and so forth. The

complaints involve physical processes at the site of the symptoms. The heart

does usually beat more forcefully and rapidly during anxiety attacks. The
various digestive disturbances are related to changes in the function of the

gastrointestinal tract, and chronic muscular tension can be demonstrated by

electrical measurements. Though inappropriate to the situation, the

symptoms do not exceed the limits of normal physiological function, do not


involve structural damage to the tissues and usually subside with the

emotional state of which they are a part. It has not so far been possible to

make rigid connections between specific symptoms and specific types of


emotion, though some loose correlations, such as those mentioned above, do

seem to exist. One or more symptoms may appear in the absence of, or

instead of, more overt emotional displays. Such symptoms are often called

affect equivalents. It may be difficult to know whether one is dealing with a


normal but inappropriate affect equivalent or with a conversion in an

involuntary system, and there may indeed be no sharp separation. Physicians


other than psychiatrists often refer to symptoms in this category as

functional symptoms, indicating that they are generated by physiological


functions and that there is no identifiable disease.

Psychophysiological symptoms are produced by autonomic nervous

system discharges to heart, lungs, digestive glands, the adrenal medulla and

The Theory and Practice of Psychotherapy with Specific Disorders 11


the digestive tract or by motor nerve discharges into skeletal muscles.

Physiological discharges in emotional states are not limited to the autonomic

and voluntary muscle systems but include the endocrine glands as well. The

biological effects of neuroendocrine secretions are so profound as to affect


the function of virtually every cell and tissue in the body. However, it is

doubtful whether the secretion of hormones during emotional discharges

gives rise to consciously perceived symptoms.

Psychic fatigue is a more complex symptom. Apparently it may be due in

part to the added work imposed on cardiovascular and muscular systems by


nervous discharge. Another contributing factor may be sleep loss. On the

other hand the sensation of fatigue may disappear suddenly with a change of

mood, suggesting that it also involves central perception and interpretation.

Psychic Aggravation of Existing Chronic Disease

It is sometimes unclear whether a particular disorder belongs in this

category or the following onePsychosomatic Diseaseswhich have


psychic components in their etiology. Where psychic factors are involved in

initial causation, they are usually also involved in subsequent aggravation.

However, the reverse need not be true. Psychic aggravation may be striking

and obvious in cases where psychic involvement in initial causation is more


difficult to establish.

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Cardiovascular diseases are among those in which psychic aggravation

is clearest. Congestive heart failure or cardiac decompensation is an excellent

example. Persons whose hearts have been damaged in such a way as to

diminish permanently the working capacity of the heart are said to have

diminished cardiac reserve. By various combinations of medication, diet and

limitation of physical exertion, it is usually possible to keep the demands

upon the heart within its capacity to meet them. So long as this is the case, the
heart disease is said to be compensated. A compensated system

decompensates when the hearts work capacity is reduced further or when

fresh demands are placed upon and exceed its capacity. One of the most

common types of fresh demand is an emotional upset, the physiological


effects of which are similar to those of physical exertion. The symptoms of

cardiac decompensation are similar regardless of the cause and include

breathlessness, accumulation of fluid in the lungs and tissues, and a shortage


of oxygen in the tissues. Hospitalization, oxygen and additional medication

are often necessary in order to reestablish a state of compensation. In a study

of twenty-five consecutive hospital admissions for congestive heart failure


(cardiac decompensation) Chambers and Reiser found that emotional stress

was a major precipitating factor in 76 percent.

Another type of mismatch between supply and demand can occur when

the coronary arteries, which carry the blood supply to heart muscles, are
diseased. In the absence of physical or emotional stress, the diseased vessels

The Theory and Practice of Psychotherapy with Specific Disorders 13


are often able to meet the heart muscles demands for the delivery of blood,

yet fail to meet the increased demands imposed by added emotional stress. In
this way emotional stress may precipitate attacks of angina pectoris3or even
ful-blown myocardial infardtions.4

In patients so disposed, emotional stress may also precipitate attacks of


irregular heartbeat, apparently mediated by emotional effects on the

autonomic nervous system. The heart is less efficient when beating

irregularly and this in turn may precipitate an attack of congestive heart

failure if cardiac reserve is already reduced by disease. The writer once had

the opportunity to observe a dramatic example of this in which a woman

suffered from obesity and severe rheumatic heart disease.5 Her disease was
adequately compensated until a rejection by her family precipitated an attack

of auricular fibrillation, one type of irregular heartbeat and congestive heart


failure. A successful physician-patient relationship was never established. The

auricular fibrillation and congestive heart failure proved refractory to

medical treatment and the patient eventually died. She did not reveal the

emotional rejection to her physicians, who learned of it through other sources

shortly before her death.

The emotional state can and frequently does alter the insulin

requirements of diabetics to such an extent that a previously well-regulated

patient is precipitated into an episode of diabetic6 acidosis7 or coma. The

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other common precipitants of acidosis are infections, failure to take insulin
and departures from the diet.

Psychosomatic Diseases

In this category belong a number of physical disease entities, usually

with pathological tissue changes and always with functioning in some organ

system which is not only inappropriate but abnormal. In addition to the

impact of emotional factors upon the course of the illness once it is


established, there are further reasons to believe that emotional factors also

play a significant role in producing the illness. It would seem reasonable to

suppose that a period of functional disorder in an organ or system might

precede the onset of a psychosomatic disease. This has been shown to be true

of ulcerative colitis8 in which the onset of structural bowel changes is usually


preceded by years of functional bowel disturbances. As another example,

peptic ulcer9 is often preceded by acid indigestion. It is frequently difficult


to establish clinically the point at which one becomes the other. The onset of

essential hypertension10 is frequently preceded by labile blood pressure.


However, psychophysiological symptoms do not necessarily lead to

psychosomatic disease.

There is no rigorously established list of diseases which are and are not

psychosomatic. In several, however, psychic etiological factors have been

The Theory and Practice of Psychotherapy with Specific Disorders 15


noted as especially prominent and are traditionally regarded as
psychosomatic. These include peptic ulcer,11 ulcerative colitis,12 essential
hypertension,13 thyrotoxicosis,14 migraine headaches,15 rheumatoid
arthritis16 and various allergic manifestations such as bronchial asthma, hay
fever, urticaria (hives) and eczema. There are also some grounds for

considering diabetes mellitus,17 pernicious anemia,18 coronary artery disease


and malignant lymphomas19 as partly psychogenic in etiology. The
appropriateness of dividing diseases into psychosomatic and non-

psychosomatic categories has been challenged and evidence introduced that

psychic factors may play a role in the development of any illness. It should be

understood, however, that at the present time only a very small minority of

workers consider any illness with pathological tissue changes to be purely


psychogenic. The majority hold that psychic and physical factors interact to

produce the disease.

PSYCHOSOMATIC ETIOLOGY

It is paradoxical that almost no one has serious doubts that


psychophysiological complaints and psychosomatic diseases exist, yet there is

very little agreement as to how they are brought about. Of the various

theories of psychosomatic etiology, none has had sufficiently rigorous and


extensive validation to warrant final acceptance or rejection. The obstacles to

accomplishing these tasks are the familiar ones in psychiatric research:

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complexity of the psychological data, confusion as to which psychic trait or

traits should be related to which illness or biological process, insufficient

precision and resolving power of the psychological methodology and

difficulty of obtaining adequate sampling of patients or adequate control of


contaminating variables.

One of the common themes running through all psychosomatic theory is

the issue of specificity versus non-specificity. Specificity implies that a specific

type of psychic event or process is related to a specific type of somatic event.

It has been suggested, for example, that compulsive personality goes with
ulcerative colitis20 ; that the emotion of anger is related to the secretion of the
noradrenalin, and fear or anxiety to the secretion of adrenaline; that intense

oral needs are related to the secretion of pepsinogen; that depressive illness

is related to depletion of brain catecholamines; and so forth. Non-specificity


implies that the quantity of psychic stress is related to the quantity of

physiological disturbance, but that the type or quality of one is unrelated to


the type or quality of the other. Most theories of non-specificity are not stated

in such extreme terms but tend in this direction. The following theories to be
discussed, and a number of others not considered here, combine specificity

and non-specificity in a variety of ways.

Pavlov

The Theory and Practice of Psychotherapy with Specific Disorders 17


Pavlov was highly critical of psychological concepts, which he regarded

as unscientific. Nevertheless his work provided one of the first

demonstrations, in the modern scientific sense, that psychosomatic processes

are possible. In the course of research on the physiology of digestion he

discovered the conditioned reflex, demonstrating that a stimulus which

became a signal of food could produce physiological effects similar to those of

food itself. The secretion of saliva and gastric juices which he studied were
end results of parasympathetic nervous activity. Pavlov was mainly

interested in these responses as a method for studying the physiology of the

cerebral cortex, of the making and breaking of temporary connections

between stimuli, and of their facilitation and inhibition. He left to others the
main tasks of studying the peripheral effects of conditioned responses. The

specificity of his theory was higha specific stimulus, related to a specific

response, in an individual with a specific set of previous experiences.

Cannon

Cannons work was crucial in providing a comprehensive view of the


autonomic or involuntary nervous system with its two divisions, the

sympathetic and the parasympathetic. He suggested that the activity levels in

all branches of the sympathetic system rise and fall together, while the

activities of the different parasympathetic branches vary independently of


each other. This was expressed by the analogy of a piano in which the keys

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represented different branches of the parasympathetic system and the loud-

soft pedal represented the sympathetic system. The parasympathetic system

promoted functions of reparation and reproduction such as digestion,

defecation, urination and copulation; it also inhibited functions promoted by


the sympathetic system. The sympathetic system discharged en masse during

fear and rage, making preparation for and supporting the metabolic

requirements of muscular exertion, fight and flight; these included


acceleration of the heart rate, shifting of blood from viscera to muscles,

mobilizing sugar into the bloodstream, accelerating the clotting of blood and

inhibiting most of the functions which are enhanced by the parasympathetic

system. Subsequent developments have supported most of his views but with

important exceptions. The sympathetic system has proved much more plastic

and flexible than he imagined, thus allowing it to participate with the


parasympathetic and endocrine systems in producing a great variety of

centrally programmed arrangements of cardiovascular, digestive and


metabolic function, both in preparation for anticipated events and in

response to current requirements. Consequently, the physiological changes in


fear and rage are much less stereotyped than he suggested.

One of the most striking departures from Cannons all-or-none view of


sympathetic function is Millers finding that autonomically mediated

functions may be modified by instrumental learning. By appropriate

contingencies of reward and punishment, rats whose skeletal muscle

The Theory and Practice of Psychotherapy with Specific Disorders 19


responses had been paralyzed by curare were trained to raise or lower their

blood pressure, to increase or decrease intestinal motility or to modify blood

vessel tone unilaterally in one or the other ear. While the role of these

mechanisms in psychosomatic etiology is unclear, their discovery opens many


possibilities which were previously unsuspected and which may be of very

high importance.

Cannons influence on psychosomatic theory was enormous, especially

since the autonomic nervous system was in his time the only known pathway

by which the brain might influence involuntary body functions. For many
years it was known that the endocrine glands regulated important metabolic

and reproductive functions and that the pituitary gland regulated the other

endocrine glands. Only relatively recently was it recognized that the brain is
an important regulator of the pituitary.

Cannons theories were nonspecific psychologically. Fear, rage,

resentment, tension, pain or anxiety, or almost any emotional disequilibrium


might provoke a fight-flight physiological pattern. Physiologically they were

highly specific.

Selye

Selye proposed the concepts of stress and the general adaptation

syndrome, after Cannon had made major contributions but before the role of

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the brain in pituitary regulation was recognized. His concepts were based on
the finding that a wide variety of injurious stimuliincluding but not limited

to toxins, burns, severe cold and mechanical injuryprovoked the release of

ACTH from the pituitary which in turn stimulated the release of corticoid

hormones from the adrenal cortex. Adrenal hormones influence a wide


variety of metabolic functions as well as biological defense reactions such as

inflammation and antibody production; without adrenal hormones it is

impossible to adapt to environmental changes and shifts in metabolic


demands. Any stimulus which provoked ACTH release was defined as a

stressor. Emotional distress was also found to provoke ACTH release and

thereby emotional stimuli were placed in a class with biologically injurious

ones. Selye recognized the psychosomatic implications of this concept and


proposed that a number of the traditionally termed psychosomatic illnesses

be called diseases of adaptation. He further suggested that they might be

caused by a disordered stress response in which there was an imbalance


between adrenal cortical hormones and somatatropic hormone.

Selyes theory, like Cannons, was psychologically nonspecific but highly


specific physiologically. Later work has confirmed and extended his finding

that emotional stimuli can provoke ACTH release. However, the stereotyped

regularity of ACTH release by emotional stimuli predicted by Selyes theory


has yet to be demonstrated. The suggestion that mild endocrine influences
due to psychic factors might contribute to physical illness remains plausible

The Theory and Practice of Psychotherapy with Specific Disorders 21


but unproved. The element of preparation for anticipated events, which

figured so highly in Pavlovs and Cannons ideas, was absent from Selyes.

However, it has since become clear that the pituitary-adrenal axis does make

anticipatory responses.

Alexander

As mentioned previously, Alexander was instrumental in


deemphasizing the role of conversion reactions in systems which are

normally involuntary and hence in the production of organic disease. From

experiences of his own and his followers in psychoanalyzing patients with

psychosomatic diseases, he concluded that a specific nuclear unconscious


conflict is characteristic of patients with each disease, that the conflict

originated in early childhood and, in most cases, long antedated the onset of
the disease. The physiological by-products of unconscious strivings

associated with the conflict caused chronic hyperactivity in the appropriate


organ system and eventually led to a breakdown of normal structure and

function in it. For example, peptic ulcer21 patients were thought to have
especially intense but repressed passive oral and oral aggressive strivings

which were defended against by reaction formations resulting in overt

behavior of ambition, hard work, self-reliance and super-independence.


Because discharge of the repressed oral longings was blocked, they set up

chronic substitute discharges in the parasympathetic innervations of the

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stomach similar to the preparations for feeding which Pavlov had

demonstrated. Essential hypertension22 was thought to be associated with

anxiety over repressed hostile competitive striving. The inhibited hostility


resulted in a substitution of chronic sympathetic nervous discharge along the

lines of the fight-flight reaction of Cannon. This in turn produced generalized

vasoconstriction, the release of adrenaline and elevation of the blood


pressure. Other formulations were proposed for migraine,23
hyperthyroidism,24 asthma, rheumatoid arthritis and ulcerative colitis.25 In

most of the formulations, pregenital and especially dependent and oral

conflicts were prominent. It was recognized that not every patient with the

appropriate conflict had the corresponding disease. Consequently, Alexander


postulated a somatic X factor which was also specific for each disease. Both

the conflict and the X factor were necessary to produce the disease, but

neither alone was sufficient. These hypotheses entailed high specificity at


both psychological and biological levels.

The psycho-analytic observations of Alexander and his followers have

proved hard to replicate and generalize. One difficulty is the sheer labor

involved in psychoanalyzing enough patients with each disease and

systematizing the material to provide an adequate and representative sample.


Another is the fact that those patients who can and will undergo

psychoanalysis already constitute a skewed sample. Yet another is that the

conflicts may not be so discreet and separable as they seem. For example,

The Theory and Practice of Psychotherapy with Specific Disorders 23


persons who inhibit their oral strivings in one sphere of life may express

them in another, and many persons can be shown to have more than one of

the postulated conflicts. Smaller scale clinical studies have not uniformly

supported the findings. In one, for example, ulcer patients were found to
express their oral and dependent strivings quite freely and openly.

On the other hand, the gastric hypersecretion of hydrochloric acid and

gastric hyper-motility due to nervous factors are characteristic of peptic ulcer

patients. Hyper-salivation has also been reported, and it has been possible to

induce gastrointestinal ulcerations by chronic stimulation of the


hypothalamus in animals.

Hypersecretion of pepsinogen is also characteristic of ulcer patients


before, during and after the development of the disease. Pepsinogen is

secreted by the cells of the gastric mucosa and then enters the blood.

Hypersecretion of pepsinogen, therefore, has several features suggestive of a

somatic X factor for peptic ulcer and provided the basis for one of the few
successful predictive studies of psychosomatic illnesses. Serum pepsinogen

was measured in 2073 Army inductees, and a sample of those with the

highest levels were selected as a group with high probability of developing


ulcers during the stress of basic training. A sample with low values were

selected as low probability subjects. The two groups of subjects were then
given a battery of psychological tests, a medical questionnaire and a complete

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radiologic examination of the upper gastrointestinal tract. At the initial
examination, a significantly greater number of ulcers was found in the high

pepsinogen group, and this group also developed a significantly greater

number of ulcers during the course of basic training. On the basis of a


prediction that evidences of orality, depression, dependence, anxiety over

expressing hostility and needs to please and placate in the psychological test

protocols would be characteristic of the high pepsinogen group, it was

possible to identify correctly 71 percent of the highs and 51 percent of the


lows. Especially strong psychological characteristics of the high pepsinogen

group were found in those who had or would develop ulcers. Other evidence

indicating that one may be a hyper-secreter from birth led Mirsky to suggest
that hypersecretion of pepsinogen may reflect a biological trait which

contributes to the development of strong oral needs and predisposes to the

development of peptic ulcers in situations of stress. Engel suggested that the

other psychosomatic illness may have analogous psychobiological


predisposing constellations and proposed the term somatopsychic-

psychosomatic disorder.

Schur

Schur finds all the claims of psychological specificity unconvincing and

argues that psychosomatic disorders tend to develop when defensive

equilibria breakdown and regression occurs. The particular kind of

The Theory and Practice of Psychotherapy with Specific Disorders 25


regression producing psychosomatic disorders is regression to primitive

modes of ego functioning with resomatization of the channels for expression

of primitive affect.

Wolff

Wolff pointed out that biological threats provoke various automatic

biological protective patterns. Among these were the protective pattern of


offense involving eating, which is one of the infants earliest aggressive

patterns. This pattern included gastric hyper-function, increased blood flow

and salivation. Another pattern was the ejection-riddance reaction involving

the large bowel, the stomach and duodenum. This included vomiting and
diarrhea, which are nonspecific reactions of the infant to noxious agents even

when the gastrointestinal tract is not invoked. Another was the holding fast
reaction of skeletal muscles and large bowel. This was characterized by

constipation with tense, aching muscles and joints. Another was the
protective reaction of nose and airways with vasodilation, hypersecretion,

contraction of smooth muscle and occlusion of airways.

According to Wolff these patterns tend to be evoked in predisposed

individuals by nonspecific threats and to persist into adulthood in fragmented

form. Prolonged and persistent use of a pattern tends to irritate the systems
involved and predispose them to disease. The predisposition to a particular

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pattern when threatened was considered to be geneticdue to stock
factorsand to be analogous to the running pattern in the horse, the

hoarding pattern of the squirrel or the retriever pattern of the dog.

Engel

On the basis of an extensive study of ulcerative colitis26 patients Engel


concluede that the disease tends to have its onset in the relationship, but only

if the subject reacts with feelings of helplessness and hopelessness. Later

work by Engel and various of his colleagues led to similar conclusions with

respect to malignant lymphomas,27 medical disease in general and


psychiatric illness. These findings also formed the basis for another of the few
successful psychosomatic predictive studies. Women entering the hospital for

biopsies of the uterine cervix were interviewed for evidence of object loss,

helplessness and hopelessness. The prediction was borne out that this state

would tend to identify those women whose cervical lesions would prove to be

malignant. The state has been termed the giving upgiven up complex and

is regarded as neither necessary nor sufficient for the development of disease


but as contributory.

As noted previously, Engels more recent theoretical interests have

turned to a more specific mechanismthe role of conversion in the

production of disease. Case material has been presented showing that a

The Theory and Practice of Psychotherapy with Specific Disorders 27


sensory conversion may evoke appropriate biological protective patterns
similar to those described by Wolff. Engel describes a female patient who as a

child had been struck along with her mother by a hit-and-run driver on a

deserted street in the dead of winter. The child had been thrown into a snow
pile and not discovered for some time. As an adult, the resurgence of

ambivalent feelings toward her mother was associated with conversion

attacks in which she not only experienced a sensation of cold but had shaking

chills, chattering teeth and blanching of her hands and feet, which became
cold to the touch.

A conversion may also produce complications, as when a sensation of

breathlessness leads to over-breathing, which then results in respiratory

alkalosis.28 The associated tetany29 and sensations of tingling about the


mouth are due to alkalosis and not part of the conversion. Engel describes

other cases in which fantasies of punishment for sexual transgression had

determined the site of skin eruptions. A soldier developed an urticarial

eruption (hives) with a linear distribution which might have been produced

by a whipping on the back of his legs, thighs and buttocks. As a boy in a very

strict orphanage, he had been whipped for peeking in the windows of the

girls dormitory. The urticarial eruption developed about an hour after he had
been apprehended loitering on the grounds of the nurses dormitory on the

military post. An enlisted man, he had hoped to see one of the nurses whom
he wanted to date. The officer who apprehended him reprimanded him

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severely and ordered him to his barracks.

Another patient, a young woman, developed an eczematoid skin


eruption around her neck where it was touched by the chain of a metal

crucifix which was given her at the time of her confirmation. She was

apprehensive about her confession, unsure whether she had sinned and felt
ashamed and unclean when the crucifix was placed around her neck. Later

eruptions occurred at the site of other metals contacting her skin if

associations of sexual guilt were aroused.

To account for the development of these lesions, Engel depends heavily

on experiments by Chapman, Goodell and Wolff. It had been known that the

pain, tenderness and inflammation following injury to the skin is enhanced


and sustained by antidromic (reverse direction) feedback activity along the

same nerve fibers which carry the nociceptive impulses. Chemical substances

(neurokinin, substance p) are released at the nerve terminals in the skin

which facilitate the local inflammatory response, lower the threshold for pain
and influence clotting mechanisms. The demonstration by Chapman et al. that

the same feedback system can be activated by hypnotic suggestion of injury to

the skin suggested to Engel that a similar mechanism might have operated in
the cases where conversion had determined the site of skin eruptions. In

these cases, skin eruptions would be complications of the conversion and not
the conversion itself, just as tetany30 is not a conversion but a complication of

The Theory and Practice of Psychotherapy with Specific Disorders 29


hyper-ventilation. Engel suggests that similar processes might also produce
pathological lesions in other systems.

In applying this line of thinking, it is necessary to distinguish between

primary and secondary symbolization. Primary symbolization is the type

described by Engel, in which a fantasy is elaborated about a body part or

system before a pathological process develops in the tissue. Secondary


symbolization means the erection of fantasies about a pathological process

after it develops.

Comment

The view of the present writer is that claims of similar conflicts, similar

instinctual makeup, similar ego structure or similar personality makeup in

patients with similar symptoms are unconvincing. The common emphasis on


oral, dependent and pregenital mechanisms have developed in an era when

psychoanalysts are becoming increasingly aware of these impulses in all


areas of psychic development and in all symptom complexes including
classical hysterical, phobic and obsessive-compulsive neuroses. While their

role is being so extensively reevaluated, it seems premature to assign them

some special role in psychosomatics. The position of Schur would seem the

soundestnamely, that there is nothing psychologically specific about


psychosomatic illness, that it simply tends to be precipitated by psychological

www.freepsychotherapybooks.org 30
regression and the breakdown of defenses. Furthermore, Engel would seem
to be entirely correct in observing that regression, disruption of defenses and

the giving upgiven up complex are most likely to occur when key object

relationships are threatened. The physiological pathways have yet to be


clarified in detail but almost certainly must involve combinations of

autonomic and neuroendocrine reactions together with local biological

defense reactions as outlined by Wolff and Engel.

THERAPEUTIC CONSIDERATIONS

With such a diverse group of disorders, there can hardly be a unitary

therapeutic approach determined by the fact that a psychosomatic disorder

exists. On the contrary, psychosomatic disorders present the entire gamut of

therapeutic problemsfrom grossly psychotic patients to healthy


neurotics. Hence they call for the entire repertoire of psychotherapeutic

approachesfrom supportive through classical psychoanalysis. The use of

behavior, group and family therapies has not been reported extensively in

these cases but undoubtedly each will eventually find its place in the
treatment of psychosomatic patients. Millers demonstration of operant

conditioning of discreet autonomic reactions is especially suggestive that

conditioning therapies might be effective in the treatment of some


psychosomatic symptoms.

The Theory and Practice of Psychotherapy with Specific Disorders 31


Despite the diversity of psychosomatic disorders and of the

psychotherapeutic approaches to them, there are two central ideas of high

importance, around which any type of therapeutic approach can be organized.

They are (a) that the onset and exacerbations of both somatic and psychiatric

illnesses tend to occur in the setting of a real, fantasied or threatened

disruption of a key object relationship, which is accompanied by disruption of

defensive and adaptive patterns, psychological regression and feelings of


helplessness and hopelessness and (b) that physical illness per se tends to

induce psychological regression; this tendency sums with any other

regressive trends which the patient may bring with him to his illness.

The utility of the concept of the key relationship lies in its non-

specificity, its simplicity and its central importance in all psychic function.

None of the more complicated specificity hypotheses have been so well

documented and none are so readily verifiable in ones everyday clinical


work. Needless to say, this concept does not substitute for a full formulation

of the psychodynamics of an individual patient; it does, however, provide a


nodal point around which a more complete formulation may be organized.

Furthermore this concept does not preclude any of the more specific

formulations which might eventually be validated as characteristic of certain


disorders. In fact if any such formulation should be valid, the key relationship

concept provides a path for arriving at it. The fact that a threat to such a
relationship disrupts defenses, induces regression and precipitates illness is

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already evidence that the relationship is invested with neurotic or psychotic

intensity derived from an object of early childhood, usually the mother. In fact

the current relationship involved in precipitating the illness is not

infrequently with the mother herself. In young adults the threat to the key
relationship is also likely to be rejection by a spouse or lover. In later life the

death or illness of a spouse is frequently the key precipitant of illnesses; in

this age range the maturation, separation or rebellion of offspring is also


often important.

It is not unusual to observe an acute rupture of a relationship, emotional


collapse and the first attack of a chronic medical illness all occurring within

hours. More frequent, however, is the onset of illness in a setting of gradual

deterioration of a relationship and gradual failure of coping mechanisms.

The psychological forces activated by physical illness have been simply

and profoundly described by Lederer. During the process of falling illthe

transition from health to illnessthe central experiences are pain,


discomfort, loss of strength and abilities, and anxiety. In addition to the

realistic fears about ones comfort and well-being, there are unconscious

anxieties, including fear of regression and passivity, fantasies that illness is a


punishment for transgressions and shame that ones weaknesses may be

exposed. At this stage one of the most potent provokers of anxiety is facing
the unknown. The nature of the illness and its implications are likely to be

The Theory and Practice of Psychotherapy with Specific Disorders 33


unknown. Diagnostic equipment and procedures are often unintelligible and
mysterious. The language spoken by physicians, nurses and technicians is

strange. Particularly devastating at this time are signs of apprehension,

uncertainty or vacillation on the part of the physician. The lack of knowledge


is well designed to draw out fantasies from the patients unconscious. The

particular patients ways of dealing with anxiety and regressive urges are

likely to be activated. These may range from denial of illness, delay in seeking

treatment, aggressiveness and provocativeness to passivity, clinging and


compliance.

Those who can tolerate the necessary degree of regression and

dependence enter a stage of accepted illness. This is characterized by

egocentricity, preoccupation with body functions, constriction of interests


and a regressed dependent relationship with doctors and nurses which bears

the stamp of whatever the patients particular relationship had been with his

parental objects in early childhood. The same caretaking persons are likely to
be seen as omnipotent and idealized by one patient and as callous and

malevolent by another. Jealousy of a nurses or doctors attention may extend


to lengths entirely out of keeping with the patients personality when well.

Romantic heterosexual fantasies are fairly frequent. If defenses against the


necessary degree of regression and dependence are too elaborate, there may

be no stage of accepted illness and no secure emotional relationships with the

medical team. This interferes with the treatment regimen and with the

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effectiveness of any treatment which he does receive. Such was undoubtedly

the case with the patient, cited earlier, in whom powerful medication was

ineffective against her auricular fibrillation and congestive heart failure.

Convalescence, the transition from accepted illness into relative health

and responsibility, is analogous to adolescence and often runs a similar


course. Doctors and nurses begin to lose their idealized qualities and may

appear somewhat depreciated, like the parents of an adolescent. Patients who

clung to the dependency on their parents may exhibit reluctance to give up

the role of sick person and the dependence to which it entitles them. This can
manifest itself in many ways such as reluctance to stop taking medicine,

reluctance to resume activity appropriate to the improved state of health or

actual recurrence of symptoms in the setting of discharge from the hospital.


The hanging on reaction tends to be intensified by long periods of

hospitalization. Thomas Manns novel The Magic Mountain deals with such a

reaction in a patient hospitalized for tuberculosis. On the other hand, patients


who broke away from their families abruptly and prematurely during

adolescence are likely to follow the same pattern with their physicians during

convalescence. Patients who separated from their parents gradually but

smoothly and progressively during adolescence are likely to have a smooth


and uneventful convalescence. The more psychosomatic the disorder, the

more likely are complications in the progression of the psychological stages of

the illness and the more likely are these complications to feed back upon the

The Theory and Practice of Psychotherapy with Specific Disorders 35


medical course of the illness.

During the stage of acute illness one faces a patient whose outbreak of
symptoms was probably precipitated by the loss of an important source of

dependent gratification, whether recognized or not, followed by disruption of

defenses, regression, helplessness and hopelessness. The illness itself will


have induced further regression. The situation is ripe for the development of

rapid and intense transference relationships. Many perceptive nonpsychiatric

physicians are very aware of these matters and handle them skillfully. Others

are totally oblivious and hence unaware of the enormous effect of their
behavior upon the course of the illness. During the acute phase of the illness,

the psychological task is to effect some temporary restitution of the

threatened object relationship, partially by replacing it with the naturally


developing transference relationship to the physician and, if practical, by

facilitating repair of the rupture with the key person. Uncovering

psychotherapy during this phase is often impractical, but proper attention to


developing good patient-physician rapport will usually facilitate the

outpouring of a great deal of material which otherwise would be heavily

defended. This readiness, even eagerness, of acutely ill patients to share

heavily charged material has been noted repeatedly. Listening to this material
and gently encouraging its revelation helps to cement the therapeutic

relationship necessary for recovery. Several years ago, Margolin advocated a

very exaggerated form of inducing this early attachment by means of

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anaclitic therapy. In this approach the physician assumed a totally giving

and totally omnipotent role toward the patient, remaining available to him at

any and all times, feeding him, stroking and massaging painful areas and

attending to all minor details of physical care. This procedure was often life-
saving but is very taxing for medical personnel to keep up for any length of

time. Equally good results can usually be obtained less dramatically by merely

being aware of the patients likes, dislikes, dependent needs and conveying
this awareness to him along with a sense of personal interest. It cannot be

emphasized strongly enough that the success or failure of this relationship

can and does spell the difference between effectiveness and ineffectiveness of

very powerful drugs or even surgical operations. If the psychotherapist enters

the case at this point, one of his major services may be to help restore a

deteriorating relationship between patient, ward personnel and physician-in-


charge.

Beyond the acute phase of illness the problems to be considered are


whether psychotherapy offers the hope of sufficient emotional maturation to

free the patient from the more neurotic aspects of his dependence on key

objects and his vulnerability to the threat of separation. In arriving at this

decision, his ego strengths, capacity for relationships and capacity for insight
will be weighed in the usual manner. Also to be considered are the questions

whether the vulnerability of his ego and his diseased organ systems can

withstand the moderate but unavoidable degrees of frustration inherent in

The Theory and Practice of Psychotherapy with Specific Disorders 37


insight giving techniques. The alternative is to establish and maintain a

supportive relationship either with the general physician or the

psychotherapist which may have to be maintained almost indefinitely, though

with dilution during times of well-being and intensification during times of


difficulty. The effectiveness of ostensibly medical visits scheduled mainly for

psychological reasons is incomprehensible to many general physicians until

they see it for themselves.

Whatever techniques are chosen, care must be taken that the general

physician keep up his contact with the patient at a sufficient level to minimize
feelings of rejection and abandonment by him during the transition period

when the psychotherapeutic relationship is being built. Once the patient is

established in psychotherapy, the problems of transference,


countertransference, resistance, hostility and dependency differ in no

characteristic way from the therapeutic problems with other patients.

However, the vulnerability of the organ systems to separation and threats of


separation must be borne in mind. During vacations and other interruptions

one must anticipate the possibility not only of anxiety, depression and

hostility but also of gastrointestinal bleeding, asthmatic attacks or whatever

the particular somatic vulnerability happens to be. Even though the therapy
seems to have gone well, additional exacerbations may occur around the time

of termination. A gradual stepwise termination with a gradually decreasing

frequency of visits is probably desirable. It is often best not to terminate

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officially at all but to act as though one assumes that the patient will call

periodically for appointments.

Our prognostic abilities for psychosomatic patients are even less than

for neurotic and psychotic patients. In general the presence of schizophrenia,

serious ego impairment, secondary gain from illness and intense strivings
toward passivity and helplessness tend to signal a poor prognosis in

psychosomatic disorders as well as in psychiatric ones. Other traits which

may be characterized generally as maturity and ego strength tend to indicate

a favorable prognosis in both the psychic and somatic spheres. With


successful psychotherapy and substantial maturation of the personality, even

fairly severely diseased organ systems may return to normal structure and

function, provided there had been no irreversible tissue damage prior to


therapy. The psychotherapist, however, should not entertain the illusion that

the vulnerability of the organ system has been removed. His contribution has

been to reduce the impact of emotional stress on this vulnerability.


Unfortunately, life provides no security against object loss or further

psychological stress. Hence the therapist must be prepared for exacerbations

and should work to prevent unrealistic illusions either in himself or in his

patient. This is not to deny that the gains through psychotherapy may spell
the difference between a productive life and invalidism, but the removal of

the organ vulnerability is probably a remaining task for biological research.

The Theory and Practice of Psychotherapy with Specific Disorders 39


Notes

1 Pain, usually in the mid-chest or left arm, occurring when diseased but still functioning coronary
arteries are temporarily unable to supply enough blood to the heart muscle to meet its
requirements. Pain is usually precipitated by exertion, emotion, a heavy meal or
exposure to cold or rarefied air and relieved by eliminating the precipitating factor or by
drugs which enlarge the lumen of the coronary artery.

2 Gradual progressive destruction of liver tissue in severe chronic alcoholism. Death eventually results
if the process is not arrested.

3 Pain, usually in the mid-chest or left arm, occurring when diseased but still functioning coronary
arteries are temporarily unable to supply enough blood to the heart muscle to meet its
requirements. Pain is usually precipitated by exertion, emotion, a heavy meal or
exposure to cold or rarefied air and relieved by eliminating the precipitating factor or by
drugs which enlarge the lumen of the coronary artery.

4 Irreversible blocking of a coronary artery so that a portion of the heart muscle is permanently
deprived of its blood supply. Symptoms of pain and breathlessness resemble the
symptoms of angina pectoris but are usually more severe and are not reversed by drugs
or by removing a precipitating factor. The affected area of heart muscle dies and is
replaced by scar tissue. During the acute stage of the illness the patients survival may be
in doubt.

5 Damage to heart valves which is sometimes an aftermath of rheumatic fever. If the damage is severe
enough, diminished cardiac reserve results, and the patient becomes subject to episodes
of cardiac decompensation or congestive heart failure.

6 In diabetes mellitus a deficiency of insulin secretion by the pancreas is the central feature of the
disease, but many other factors are involved. The naturally occurring disease is often
much more severe than that caused by total removal of the pancreas. There may possibly
be several types of diabetes mellitus. Diabetes insipidus is an entirely different disorder.

7 An abnormally acid condition of the blood resulting from the accumulation of improperly
metabolized materials. This occurs when insulin requirements exceed the insulin dose
by too much for too long. Coma results when the condition is severe, and death will then
follow if treatment is not prompt and vigorous.

www.freepsychotherapybooks.org 40
8 A generalized disease of unknown cause. Some of the outstanding symptoms are fever and bloody
diarrhea or sometimes constipation. Ulcers form in the inner lining and muscular walls
of the large intestine (colon) and may become secondarily infected by bacteria which
inhabit the bowel. The disease is usually chronic and episodic, often leading to extensive
scar formation in the large intestine. Occasionally the course is rapid and progressive,
resulting in death.

9 A disease of unknown cause involving the lower stomach or upper duodenum. Outstanding
symptoms in uncomplicated cases include burning and cramping in the mid or upper
abdominal area, usually when the stomach is empty. Some relief is often afforded by the
intake of milk or mild anti-acids. In the affected area a single craterlike ulcer erodes the
inner lining of the stomach or duodenum and into the muscular wall. Motility and acid
secretion by the stomach and duodenum are usually increased.

10 Abnormally elevated blood pressure (hypertension) in the absence of any known cause, such as
impaired kidney function or hormone-secreting tumors. If prolonged and severe, the
complications may include overworking of the heart or damage to the blood vessels of
brain, heart or kidney.

11 A disease of unknown cause involving the lower stomach or upper duodenum. Outstanding
symptoms in uncomplicated cases include burning and cramping in the mid or upper
abdominal area, usually when the stomach is empty. Some relief is often afforded by the
intake of milk or mild anti-acids. In the affected area a single craterlike ulcer erodes the
inner lining of the stomach or duodenum and into the muscular wall. Motility and acid
secretion by the stomach and duodenum are usually increased.

12 A generalized disease of unknown cause. Some of the outstanding symptoms are fever and bloody
diarrhea or sometimes constipation. Ulcers form in the inner lining and muscular walls
of the large intestine (colon) and may become secondarily infected by bacteria which
inhabit the bowel. The disease is usually chronic and episodic, often leading to extensive
scar formation in the large intestine. Occasionally the course is rapid and progressive,
resulting in death.

13 Abnormally elevated blood pressure (hypertension) in the absence of any known cause, such as
impaired kidney function or hormone-secreting tumors. If prolonged and severe, the
complications may include overworking of the heart or damage to the blood vessels of
brain, heart or kidney.

The Theory and Practice of Psychotherapy with Specific Disorders 41


14 Also called Graves disease, Basedows disease and hyperthyroidism. Its cause is unknown. The
central feature of the disorder is overproduction of thyroid hormones which are
responsible for many of the symptoms, which include enlargement of the thyroid gland
(goiter), general acceleration of the metabolic rate, intolerance to warm temperatures,
restlessness, rapid heartbeat, perspiration and sometimes protrusion of the eyeballs.
Rather similar symptoms may be produced by hormone secreting tumors of the thyroid,
but the mechanism of these disorders is different.

15 Episodic headaches, usually severe, throbbing and confined to one side of the head. They are often
preceded by various visual phenomena and followed by nausea and vomiting. The pre-
headache phenomena are associated with constriction and the headache with dilation of
cranial arteries. During the headache, the tissues surrounding cranial arteries on the
involved side are swollen and tender.

16 A disease of unknown cause which is usually chronic and recurring. Its outstanding feature is
inflammation of the lining membranes of various joints which causes pain, swelling and
redness over the area. In the advanced stages there may be destruction of joint cartilage,
scar tissue formation and fusion of joints.

17 In diabetes mellitus a deficiency of insulin secretion by the pancreas is the central feature of the
disease, but many other factors are involved. The naturally occurring disease is often
much more severe than that caused by total removal of the pancreas. There may possibly
be several types of diabetes mellitus. Diabetes insipidus is an entirely different disorder.

18 Anemia due to deficiency of vitamin B12. It results from failure of the stomach to secrete enough of
a material which enables the intestine to absorb dietary vitamin B12.

19 A collective term referring to various malignant disorders involving spleen, lymph nodes and other
lymphatic and related tissues. These disorders include Hodgkins disease, lymphatic
leukemia and lympho sarcomas.

20 A generalized disease of unknown cause. Some of the outstanding symptoms are fever and bloody
diarrhea or sometimes constipation. Ulcers form in the inner lining and muscular walls
of the large intestine (colon) and may become secondarily infected by bacteria which
inhabit the bowel. The disease is usually chronic and episodic, often leading to extensive
scar formation in the large intestine. Occasionally the course is rapid and progressive,
resulting in death.

www.freepsychotherapybooks.org 42
21 A disease of unknown cause involving the lower stomach or upper duodenum. Outstanding
symptoms in uncomplicated cases include burning and cramping in the mid or upper
abdominal area, usually when the stomach is empty. Some relief is often afforded by the
intake of milk or mild anti-acids. In the affected area a single craterlike ulcer erodes the
inner lining of the stomach or duodenum and into the muscular wall. Motility and acid
secretion by the stomach and duodenum are usually increased.

22 Abnormally elevated blood pressure (hypertension) in the absence of any known cause, such as
impaired kidney function or hormone-secreting tumors. If prolonged and severe, the
complications may include overworking of the heart or damage to the blood vessels of
brain, heart or kidney.

23 Episodic headaches, usually severe, throbbing and confined to one side of the head. They are often
preceded by various visual phenomena and followed by nausea and vomiting. The pre-
headache phenomena are associated with constriction and the headache with dilation of
cranial arteries. During the headache, the tissues surrounding cranial arteries on the
involved side are swollen and tender.

24 Also called Graves disease, Basedows disease and hyperthyroidism. Its cause is unknown. The
central feature of the disorder is overproduction of thyroid hormones which are
responsible for many of the symptoms, which include enlargement of the thyroid gland
(goiter), general acceleration of the metabolic rate, intolerance to warm temperatures,
restlessness, rapid heartbeat, perspiration and sometimes protrusion of the eyeballs.
Rather similar symptoms may be produced by hormone secreting tumors of the thyroid,
but the mechanism of these disorders is different.

25 A generalized disease of unknown cause. Some of the outstanding symptoms are fever and bloody
diarrhea or sometimes constipation. Ulcers form in the inner lining and muscular walls
of the large intestine (colon) and may become secondarily infected by bacteria which
inhabit the bowel. The disease is usually chronic and episodic, often leading to extensive
scar formation in the large intestine. Occasionally the course is rapid and progressive,
resulting in death.

26 A generalized disease of unknown cause. Some of the outstanding symptoms are fever and bloody
diarrhea or sometimes constipation. Ulcers form in the inner lining and muscular walls
of the large intestine (colon) and may become secondarily infected by bacteria which
inhabit the bowel. The disease is usually chronic and episodic, often leading to extensive

The Theory and Practice of Psychotherapy with Specific Disorders 43


scar formation in the large intestine. Occasionally the course is rapid and progressive,
resulting in death.

27 A collective term referring to various malignant disorders involving spleen, lymph nodes and other
lymphatic and related tissues. These disorders include Hodgkins disease, lymphatic
leukemia and lympho sarcomas.

28 Alkalosis (the opposite of acidosis) refers to any state in which the blood is abnormally alkaline. In
respiratory alkalosis the primary cause is over-breathing, which drives the carbon
dioxide level in the blood (and thereby the carbonic acid level also) to abnormally low
levels. In alkaline blood the solubility of calcium compounds (and hence the serum
calcium concentration) is reduced. This causes a condition known as tetany.

29 A syndrome which includes extension of the extremities with a characteristic flexion of the ankles
and wrists known as carpopedal spasm. There is also twitching of the extremities and
sensations of tingling about the mouth. The cause is low serum calcium concentration.

30 A syndrome which includes extension of the extremities with a characteristic flexion of the ankles
and wrists known as carpopedal spasm. There is also twitching of the extremities and
sensations of tingling about the mouth. The cause is low serum calcium concentration.

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