Osteoporosis. Laboratory Findings and Pathophysiology.

Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 5

LABORATORY AND DIAGNOSTIC PROCEDURES

Hematologic Studies
NORMAL VALUES

RESULTS

Hemoglobin
Hematocrit

120-160 g/L
0.37-0.47 vol.fr

N
N

Red Blood Cell Count

4.2-5.4 x 1012/L

4.5-11.0 x 109/L

9.6 x 109/L

50-70%
50-70%
2-5%
20-40%
3-9%

N
N
N
N
N

60 %
50 %
3%
30 %
7%

Adequate.

N
N
N
N

91.0 f
28.8 pg
31.5g/dl
12.9

White Blood Cell


Count
Neutrophil
Segmenter
Stab
Lymphocyte
Monocyte

125 g/l
0.37 vol/fr
4.28 x

1012 /L

150-450x 10

Platelet Count

/L
74-100f
25.4-34.6pg
31-37g/L
11-16%

MCV
MCHC
MCH
RDW

SIGNIFICANC
E
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.
Normal.

Blood Chemistry
NORMAL VALUES
Sodium
Potassium
Calcium
Phosphorous

135 148 mmol/Li


3.8 5.5 mmol/Li
2.12 2.52 mmol/Li
2.4 - 4.1 mg/dL

RESULTS
N
N
N
N

142.8 mmol/Li
4.60 mmol/Li
2.36 mmol/Li
2.8 mg/dL

SIGNIFICANCE
Normal.
Normal.
Normal.
Normal.

Bone Scan

DXA
(hip)

NORMAL VALUES

RESULTS

Not more than


1.0 SD

(-) 2.5

SIGNIFICANCE
Indicative of osteoporosis based on
WHO Criteria.

significant role in regulating calcium uptake and release and in regulating


osteoblastic activity.
Osteoporosis
The bone mineral density is assessed and interpreted as follows according to
the World Health Organization (WHO):
CATEGORY

t-SCORE

Normal

Not more than 1.0 standard deviation below the young


adult mean

Osteopenia

Between 1.0 2.5 SD below the mean

Osteoporosis

More than 2.5 SD below the young adult mean

Severe or
Established

More than 2.5 SD below the young adult mean with a


fracture

gradual collapse of the vertebra


back pain and decrease in height

susceptibility to fractures

det

Figure 1. Pathophysiology of Osteoporosis

You might also like