Researchers from TU Darmstadt, TU Dresden, Hewlett Packard Enterprise (HPE), and Intel have developed advanced applications that combine HPC simulations with AI techniques using the open-source computational fluid dynamics solver OpenFOAM and the HPE-led SmartSim AI/ML library. These applications show promise for improving the accuracy and capabilities of traditional scientific and engineering modelling with data-driven techniques. These types of techniques can lead to accelerated scientific discovery and engineering prototyping by allowing researchers to run larger or more complex simulations on modern computational resources.