The m.11778G>A variant of the MT-ND4 gene causes Leber hereditary optic neuropathy (LHON), and the gene therapy lenadogene nolparvovec has shown sustained bilateral improvement in visual acuity and quality of life for up to 5 years in patients. https://ja.ma/41Jiviy
JAMA Ophthalmology
Book and Periodical Publishing
Chicago, Illinois 11,258 followers
A member of the JAMA Network, which includes JAMA, 11 specialty journals, and JAMA Network Open.
About us
JAMA Ophthalmology is published online weekly, every Thursday, and in 12 print/online issues a year. The journal receives more than 4.6 million annual article views and downloads. Without any author fees, all research articles are made free access online 12 months after publication on the website. In addition, the online version is freely available or nearly so to institutions in developing countries through the World Health Organization's HINARI program. JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. The journal’s acceptance rate is 15%. The median time to first decision is 3 days, and 36 days with review. The Journal Impact Factor is 8.1, one of the highest ranking among ophthalmology journals. All articles are published online first. Neil M. Bressler, MD, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, is the editor in chief.
- Website
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https://jamanetwork.com/journals/jamaophthalmology
External link for JAMA Ophthalmology
- Industry
- Book and Periodical Publishing
- Company size
- 5,001-10,000 employees
- Headquarters
- Chicago, Illinois
- Founded
- 1869
- Specialties
- Ophthalmology
Updates
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Despite the effectiveness of early treatment for diabetic retinopathy (DR) in preventing severe vision loss, the annual monitoring rate among US adults with diabetes remains below target. https://ja.ma/3Dmb0nN
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A 4-year-old child presented with a 3-day history of worsening redness, pain, and swelling over the left lower eyelid and nose. What would you do next? https://ja.ma/4f9Ttw5
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Biallelic pathogenic variants in UBAP1L were identified in six probands with retinal dystrophies, establishing UBAP1L as a disease gene for inherited retinal diseases in humans. https://ja.ma/4gkSUR9
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A deep learning algorithm accurately discriminated between potentially blinding but treatable arteritic anterior ischemic optic neuropathy from non-ischemic anterior ischemic optic neuropathy. https://ja.ma/4f68gbo
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Most viewed in the last 7 days from JAMA Ophthalmology: Compared with initiation of a dipeptidyl peptidase 4 inhibitor, empagliflozin initiation was not associated with incident nonproliferative diabetic retinopathy (DR). https://ja.ma/3Zss2ry
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A 75-year-old woman with a history of essential thrombocythemia presented with 3 months of progressively enlarging right upper eyelid lesions. Examination revealed a thickened eyelid margin, madarosis, and erythema with some tenderness to palpation but an otherwise normal ocular examination. What would you do next? https://ja.ma/4gxaRfF
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This case report describes an outer retinal abnormality associated with taking a RET inhibitor during a clinical trial in a 52-year-old patient with right lung adenocarcinoma and a RET gene fusion. https://ja.ma/3VBPEJs
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Most viewed in the last 7 days from JAMA Ophthalmology: Compared with initiation of a dipeptidyl peptidase 4 inhibitor, empagliflozin initiation was not associated with incident nonproliferative diabetic retinopathy (DR). https://ja.ma/4fn6SB3
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In young adults with type 1 diabetes, hyperglycemia remains the dominant risk factor for diabetic retinopathy, but overweight, obesity, and hypertension also significantly increase the risk. https://ja.ma/49vomtK
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