Sample Preparation Collaborative Articles

What are the advantages and disadvantages of using automated LLE systems versus manual LLE methods?

Learn the advantages and disadvantages of using automated LLE systems versus manual LLE methods for sample preparation in analytical chemistry.

Sample Preparation

What are the main advantages of using SPE over liquid-liquid extraction (LLE)?

2 contributions 5 months ago

Learn what solid phase extraction (SPE) is, how it works, and why it is more efficient, selective, and environmentally friendly than liquid-liquid extraction (LLE).

Sample Preparation

What are the best practices for sample homogenization and filtration?

4 contributions 5 months ago

Learn how to homogenize and filter biological samples for optimal extraction quality and safety evaluation.

Sample Preparation

How do you select the appropriate membrane size and type for buffer exchange and diafiltration?

4 contributions

Learn how to use buffer exchange and diafiltration methods for sample preparation. Find out how to select the optimal membrane size and type for your application.

Sample Preparation

How do you troubleshoot concentration and desalting issues in your workflow?

1 contribution

Learn how to troubleshoot common issues that can affect your sample quality and quantity during concentration and desalting processes, and how to optimize your…

Sample Preparation

How do you ensure sample representativeness and homogeneity in sample preparation?

2 contributions

Learn how to ensure sample representativeness and homogeneity in sample preparation for different sample types. Follow these best practices and tips for reliable…

Sample Preparation

What are the best practices and tips for RNA sample preparation in a high-throughput setting?

1 contribution

Learn the best practices and tips for RNA sample preparation in a high-throughput setting, covering sample collection, homogenization, extraction, purification, and…

Sample Preparation

How do you ensure the quality and reproducibility of LLE results?

4 contributions 5 months ago

Learn how to optimize your liquid-liquid extraction procedure and ensure reliable and reproducible sample preparation for various applications.

Sample Preparation

How do you reduce sample variability and bias in biomarker studies?

0 contributions

Learn how to choose the right sample type and size, follow standardized protocols and best practices, and apply statistical methods and tools to reduce sample…

Sample Preparation

How do you troubleshoot sample preparation issues in multiplex PCR?

0 contributions

Learn how to troubleshoot primer design, template quality, and reaction optimization issues in multiplex PCR for molecular diagnostics and quality control.

Sample Preparation

How do you optimize the selectivity of solid phase extraction (SPE)?

0 contributions

Learn how to optimize the selectivity of solid phase extraction (SPE) by choosing the right sorbent type, size, shape, amount, bed depth, mode of interaction, pH…

Sample Preparation

How do you reduce the solvent consumption and waste generation in extraction processes?

1 contribution

Learn how to reduce the solvent consumption and waste generation in your extraction processes with these practical tips on solvent selection, optimization…

Sample Preparation

What are the best methods to reduce matrix effects in bioanalytical sensors?

0 contributions

Learn about sample preparation, sensor design, and signal processing methods to reduce matrix effects and improve sensor performance and accuracy.

Sample Preparation

How do you choose the right PCR primers and probes?

0 contributions

Learn how to design, test, and optimize PCR primers and probes for your target DNA sequence and PCR type in this sample preparation guide.

Sample Preparation

How do you integrate concentration and desalting steps with other sample preparation techniques?

0 contributions

Learn how to overcome the challenges and improve the quality and stability of your sample by integrating concentration and desalting steps with other sample…

Sample Preparation

How do you validate the recovery and reproducibility of microwave-assisted extraction methods?

0 contributions

Learn how to validate the recovery and reproducibility of microwave-assisted extraction methods for various analytes and matrices in six easy steps.

Sample Preparation

How do you monitor and control the temperature and pressure in pressurized liquid extraction?

0 contributions

Learn how to monitor and control the temperature and pressure of the extraction solvent in pressurized liquid extraction (PLE) for optimal results.

Sample Preparation

What are the challenges and opportunities of using green extraction techniques?

0 contributions

Learn what are green extraction techniques, why they are beneficial for sample preparation, what are their challenges and opportunities, how to choose a suitable…

Sample Preparation

How do you keep up with the latest developments and innovations in microwave-assisted extraction?

0 contributions

Learn about online platforms, journals, publications, and conferences that focus on microwave-assisted extraction (MAE) and sample preparation in this article.

Sample Preparation

What are the key factors to consider when scaling up protein purification protocols?

0 contributions

Learn about the key factors to consider when scaling up protein purification protocols, such as expression system, purification method, buffer conditions, protein…

Sample Preparation

How do you deal with emulsion formation and stability in liquid-liquid extraction?

0 contributions

Learn how to deal with emulsion formation and stability in liquid-liquid extraction, and how to avoid or minimize them in your sample preparation.

Sample Preparation

How do you troubleshoot and overcome background noise and contamination issues in your sample preparation?

0 contributions

Learn how to identify, minimize, and overcome background noise and contamination issues in your sample preparation, especially when using enrichment and depletion…

Sample Preparation

How do you keep up with the latest developments and innovations in sample preparation for extraction?

2 contributions

Learn what extraction efficiency and yield are, how to measure them, and how to improve them with different sample preparation techniques.

Sample Preparation

What are the main safety precautions and challenges when performing microwave-assisted extraction?

0 contributions

Learn the main aspects of MAE protocols and procedures, and how to overcome the potential difficulties of this fast and efficient extraction technique.

Sample Preparation

How do you scale up LLE methods for large-volume or complex samples?

0 contributions

Learn how to scale up liquid-liquid extraction methods for sample preparation in analytical chemistry. Find out the best practices for solvent selection, phase…

Sample Preparation

How do you evaluate the efficiency and quality of cell disruption?

0 contributions

Learn about the common techniques and parameters for cell disruption in sample preparation, and how to measure their efficiency and quality.

Sample Preparation

What are the latest trends and innovations in homogenization and lysis buffer development and research?

0 contributions

Learn how to choose the right buffer for homogenizing and lysing your samples. Discover factors to consider and latest innovations in buffer design.

Sample Preparation